Arginine-rich histones have strong antiviral activity for influenza A viruses

Innate Immunity

Volumn 21, Issue 7, 2015, Pages 736-745

  Hoeksema, Marloes ^a,b   Tripathi, Shweta ^a   White, Mitchell ^a   Qi, Li ^c   Taubenberger, Jeffery ^c   Van Eijk, Martin ^b   Haagsman, Henk ^b   Hartshorn, Kevan L ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UTRECHT UNIVERSITY   (Netherlands)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

antimicrobial peptide; Histones; influenza; innate immunity; pandemic

Indexed keywords

ARGININE; HISTONE; HISTONE H2A; HISTONE H2B; HISTONE H4; SIALIDASE; VIRUS RNA; ANTIVIRUS AGENT; PROTEIN BINDING;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL LYSATE; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; INFLUENZA A VIRUS (H1N1); INFLUENZA A VIRUS (H3N2); LIGHT ABSORPTION; NONHUMAN; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SUPERNATANT; TRANSMISSION ELECTRON MICROSCOPY; VIRUS PARTICLE; VIRUS REPLICATION; CELL LINE; GENETICS; HUMAN; IMMUNOLOGY; INFLUENZA; INFLUENZA A VIRUS; INNATE IMMUNITY; METABOLISM; PHYSIOLOGY; VIROLOGY; VIRUS ENTRY;

ANTIVIRAL AGENTS; ARGININE; CELL LINE; EPITHELIAL CELLS; HISTONES; HUMANS; IMMUNITY, INNATE; INFLUENZA A VIRUS; INFLUENZA, HUMAN; PROTEIN BINDING; VIRUS INTERNALIZATION; VIRUS REPLICATION;

EID: 84942114244     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425915593794     Document Type: Article

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