Hapivirins and diprovirins: Novel θ-defensin analogs with potent activity against influenza A virus

Journal of Immunology

Volumn 188, Issue 6, 2012, Pages 2759-2768

  Doss, Mona ^a   Ruchala, Piotr ^b   Tecle, Tesfaldet ^a   Gantz, Donald ^a   Verma, Anamika ^a   Hartshorn, Alex ^a   Crouch, Erika C ^c   Luong, Hai ^b,d   Micewicz, Ewa D ^b   Lehrer, Robert I ^b   Hartshorn, Kevan L ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ASTELLAS PHARMA GLOBAL DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; DEFENSIN; DIPROVIRIN DERIVATIVE; HAPIVIRIN DERIVATIVE; NEW DRUG; SURFACTANT PROTEIN D; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HYDROPHOBICITY; INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; MACROPHAGE; NEUTROPHIL; NONHUMAN; PEPTIDE ANALYSIS; PHAGOCYTOSIS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; VIRUS NEUTRALIZATION; VIRUS STRAIN;

AMINO ACID SEQUENCE; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CHEMISTRY TECHNIQUES, SYNTHETIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEFENSINS; DOGS; HUMANS; INFLUENZA A VIRUS; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR SEQUENCE DATA; MONOCYTES; NEUTROPHILS; PEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84857815824     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101335     Document Type: Article

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