-
1
-
-
0029553183
-
An overview of epithelio-mesenchymal transformation
-
Hay ED. An overview of epithelio-mesenchymal transformation. Acta Anatomica 1995;154:8-20.
-
(1995)
Acta Anatomica
, vol.154
, pp. 8-20
-
-
Hay, E.D.1
-
2
-
-
12944260524
-
Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes
-
Savagner P, Kusewitt DF, Carver EA, Magnino F, Choi C, Gridley T, et al. Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes. J Cell Physiol 2005;202:858-66.
-
(2005)
J Cell Physiol
, vol.202
, pp. 858-866
-
-
Savagner, P.1
Kusewitt, D.F.2
Carver, E.A.3
Magnino, F.4
Choi, C.5
Gridley, T.6
-
3
-
-
47549102418
-
Epithelial mesenchymal transition traits in human breast cancer cell lines
-
Blick T, Widodo E, Hugo H, Waltham M, Lenburg ME, Neve RM, et al. Epithelial mesenchymal transition traits in human breast cancer cell lines. Clin Exp Metastasis 2008;25:629-42.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 629-642
-
-
Blick, T.1
Widodo, E.2
Hugo, H.3
Waltham, M.4
Lenburg, M.E.5
Neve, R.M.6
-
4
-
-
34547702484
-
Breast cancer progression: Controversies and consensus in the molecular mechanisms of metastasis and EMT
-
Cowin P, Welch DR. Breast cancer progression: controversies and consensus in the molecular mechanisms of metastasis and EMT. J Mammary Gland Biol Neoplasia 2007;12:99-102.
-
(2007)
J Mammary Gland Biol Neoplasia
, vol.12
, pp. 99-102
-
-
Cowin, P.1
Welch, D.R.2
-
5
-
-
84892820840
-
Histone deacetylase inhibitor entinostat reverses epithelial to mesenchymal transition of breast cancer cells by reversing the repression of E-cadherin
-
Shah P, Gau Y, Sabnis G. Histone deacetylase inhibitor entinostat reverses epithelial to mesenchymal transition of breast cancer cells by reversing the repression of E-cadherin. Breast Cancer Res Treat 2014;143:99-111.
-
(2014)
Breast Cancer Res Treat
, vol.143
, pp. 99-111
-
-
Shah, P.1
Gau, Y.2
Sabnis, G.3
-
6
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001;414:105-11.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
7
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 2003;100:3983-8.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
8
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008;133:704-15.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
-
9
-
-
51449085561
-
Generation of breast cancer stem cells through epithelial-mesenchymal transition
-
Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, Puisieux A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One 2008;3:e2888.
-
(2008)
PLoS One
, vol.3
-
-
Morel, A.P.1
Lievre, M.2
Thomas, C.3
Hinkal, G.4
Ansieau, S.5
Puisieux, A.6
-
10
-
-
84866324123
-
Cancer stem cells and epithelial-mesenchymal transition: Concepts and molecular links
-
Scheel C, Weinberg RA. Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links. Semin Cancer Biol 2012;22:396-403.
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 396-403
-
-
Scheel, C.1
Weinberg, R.A.2
-
11
-
-
84878523316
-
Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer
-
Bisso A, Faleschini M, Zampa F, Capaci V, De Santa J, Santarpia L, et al. Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer. Cell Cycle 2013;12:1679-87.
-
(2013)
Cell Cycle
, vol.12
, pp. 1679-1687
-
-
Bisso, A.1
Faleschini, M.2
Zampa, F.3
Capaci, V.4
De Santa, J.5
Santarpia, L.6
-
12
-
-
80053194900
-
miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase
-
Song L, Lin C, Wu Z, Gong H, Zeng Y, Wu J, et al. miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase. PLoS One 2011;6:e25454.
-
(2011)
PLoS One
, vol.6
-
-
Song, L.1
Lin, C.2
Wu, Z.3
Gong, H.4
Zeng, Y.5
Wu, J.6
-
13
-
-
84899897538
-
MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1
-
Ji D, Chen Z, Li M, Zhan T, Yao Y, Zhang Z, et al. MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1. Mol Cancer 2014;13:86.
-
(2014)
Mol Cancer
, vol.13
, pp. 86
-
-
Ji, D.1
Chen, Z.2
Li, M.3
Zhan, T.4
Yao, Y.5
Zhang, Z.6
-
14
-
-
68949170622
-
Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells
-
Ji J, Yamashita T, Budhu A, Forgues M, Jia HL, Li C, et al. Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells. Hepatology 2009;50:472-80.
-
(2009)
Hepatology
, vol.50
, pp. 472-480
-
-
Ji, J.1
Yamashita, T.2
Budhu, A.3
Forgues, M.4
Jia, H.L.5
Li, C.6
-
15
-
-
79953043006
-
Transforming growth factor-beta regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM
-
Wang Y, YuY, Tsuyada A, Ren X,WuX, Stubblefield K, et al. Transforming growth factor-beta regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM. Oncogene 2011;30:1470-80.
-
(2011)
Oncogene
, vol.30
, pp. 1470-1480
-
-
Wang, Y.1
Yu, Y.2
Tsuyada, A.3
Ren, X.4
Wu, X.5
Stubblefield, K.6
-
16
-
-
60549089850
-
Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen
-
Sabnis G, Schayowitz A, Goloubeva O, Macedo L, Brodie A. Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen. Cancer Res 2009;69:1416-28.
-
(2009)
Cancer Res
, vol.69
, pp. 1416-1428
-
-
Sabnis, G.1
Schayowitz, A.2
Goloubeva, O.3
Macedo, L.4
Brodie, A.5
-
17
-
-
79952237710
-
Functional activation of the estrogen receptor-alpha and aromatase by the HDAC inhibitor entinostat sensitizes ER-negative tumors to letrozole
-
Sabnis GJ, Goloubeva O, Chumsri S, Nguyen N, Sukumar S, Brodie AM. Functional activation of the estrogen receptor-alpha and aromatase by the HDAC inhibitor entinostat sensitizes ER-negative tumors to letrozole. Cancer Res 2011;71:1893-903.
-
(2011)
Cancer Res
, vol.71
, pp. 1893-1903
-
-
Sabnis, G.J.1
Goloubeva, O.2
Chumsri, S.3
Nguyen, N.4
Sukumar, S.5
Brodie, A.M.6
-
18
-
-
84890478151
-
HDAC inhibitor entinostat restores responsiveness of letrozole resistant MCF-7Ca xenografts to AIs through modulation of Her-2
-
Sabnis GJ, Goloubeva OG, Kazi AA, Shah P, Brodie AH. HDAC inhibitor entinostat restores responsiveness of letrozole resistant MCF-7Ca xenografts to AIs through modulation of Her-2. Mol Cancer Ther 2013;12:2804-16.
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 2804-2816
-
-
Sabnis, G.J.1
Goloubeva, O.G.2
Kazi, A.A.3
Shah, P.4
Brodie, A.H.5
-
19
-
-
77956302698
-
Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers
-
Deng S, Yang X, Lassus H, Liang S, Kaur S, Ye Q, et al. Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers. PLoS One 2010;5:e10277.
-
(2010)
PLoS One
, vol.5
-
-
Deng, S.1
Yang, X.2
Lassus, H.3
Liang, S.4
Kaur, S.5
Ye, Q.6
-
20
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007;1:555-67.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
Monville, F.4
Dutcher, J.5
Brown, M.6
-
21
-
-
67649884727
-
Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression
-
Morimoto K, Kim SJ, Tanei T, Shimazu K, Tanji Y, Taguchi T, et al. Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression. Cancer Sci 2009;100:1062-8.
-
(2009)
Cancer Sci
, vol.100
, pp. 1062-1068
-
-
Morimoto, K.1
Kim, S.J.2
Tanei, T.3
Shimazu, K.4
Tanji, Y.5
Taguchi, T.6
-
22
-
-
0036154828
-
The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells
-
Kim M, Turnquist H, Jackson J, Sgagias M, Yan Y, Gong M, et al. The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clin Cancer Res 2002;8:22-8.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 22-28
-
-
Kim, M.1
Turnquist, H.2
Jackson, J.3
Sgagias, M.4
Yan, Y.5
Gong, M.6
-
23
-
-
84858002750
-
Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance
-
Natarajan K, Xie Y, Baer MR, Ross DD. Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance. Biochem Pharmacol 2012;83:1084-103.
-
(2012)
Biochem Pharmacol
, vol.83
, pp. 1084-1103
-
-
Natarajan, K.1
Xie, Y.2
Baer, M.R.3
Ross, D.D.4
-
24
-
-
84055216937
-
Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence
-
Tran DD, Corsa CA, Biswas H, Aft RL, Longmore GD. Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence. Mol Cancer Res 2011;9:1644-57.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 1644-1657
-
-
Tran, D.D.1
Corsa, C.A.2
Biswas, H.3
Aft, R.L.4
Longmore, G.D.5
-
25
-
-
3142742249
-
Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro
-
Brown KA, Aakre ME, Gorska AE, Price JO, Eltom SE, Pietenpol JA, et al. Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro. Breast Cancer Res 2004;6:R215-31.
-
(2004)
Breast Cancer Res
, vol.6
, pp. R215-R231
-
-
Brown, K.A.1
Aakre, M.E.2
Gorska, A.E.3
Price, J.O.4
Eltom, S.E.5
Pietenpol, J.A.6
-
26
-
-
84873859029
-
TGF-beta upregulates miR-181a expression to promote breast cancer metastasis
-
Taylor MA, Sossey-Alaoui K, Thompson CL, Danielpour D, Schiemann WP. TGF-beta upregulates miR-181a expression to promote breast cancer metastasis. J Clin Invest 2013;123:150-63.
-
(2013)
J Clin Invest
, vol.123
, pp. 150-163
-
-
Taylor, M.A.1
Sossey-Alaoui, K.2
Thompson, C.L.3
Danielpour, D.4
Schiemann, W.P.5
-
27
-
-
84868295693
-
A new mouse model for the study of human breast cancer metastasis
-
Iorns E, Drews-Elger K, Ward TM, Dean S, Clarke J, Berry D, et al. A new mouse model for the study of human breast cancer metastasis. PLoS ONE 2012;7:e47995.
-
(2012)
PLoS ONE
, vol.7
-
-
Iorns, E.1
Drews-Elger, K.2
Ward, T.M.3
Dean, S.4
Clarke, J.5
Berry, D.6
-
28
-
-
77956178360
-
EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
-
Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 2010;29:4741-51.
-
(2010)
Oncogene
, vol.29
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
-
29
-
-
84868208585
-
E-cadherin promotor methylation and mutation are inversely related to motility capacity of breast cancer cells
-
van Horssen R, Hollestelle A, Rens JA, Eggermont AM, Schutte M, Ten Hagen TL. E-cadherin promotor methylation and mutation are inversely related to motility capacity of breast cancer cells. Breast Cancer Res Treat 2012;136:365-77.
-
(2012)
Breast Cancer Res Treat
, vol.136
, pp. 365-377
-
-
Van Horssen, R.1
Hollestelle, A.2
Rens, J.A.3
Eggermont, A.M.4
Schutte, M.5
Ten Hagen, T.L.6
-
30
-
-
33644780111
-
Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha
-
Kong X, Lin Z, Liang D, Fath D, Sang N, Caro J. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha. Mol Cell Biol 2006;26:2019-28.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2019-2028
-
-
Kong, X.1
Lin, Z.2
Liang, D.3
Fath, D.4
Sang, N.5
Caro, J.6
-
31
-
-
84860511076
-
Downregulation of hypoxia-related responses by novel antitumor histone deacetylase inhibitors in MDA-MB-231 breast cancer cells
-
Naldini A, Filippi I, Cini E, Rodriquez M, Carraro F, Taddei M. Downregulation of hypoxia-related responses by novel antitumor histone deacetylase inhibitors in MDA-MB-231 breast cancer cells. Anticancer Agents Med Chem 2012;12:407-13.
-
(2012)
Anticancer Agents Med Chem
, vol.12
, pp. 407-413
-
-
Naldini, A.1
Filippi, I.2
Cini, E.3
Rodriquez, M.4
Carraro, F.5
Taddei, M.6
-
32
-
-
84875204442
-
Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer
-
Giudice FS, Pinto DS Jr., Nor JE, Squarize CH, Castilho RM. Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer. PLoS One 2013;8:e58672.
-
(2013)
PLoS One
, vol.8
-
-
Giudice, F.S.1
Pinto, D.S.2
Nor, J.E.3
Squarize, C.H.4
Castilho, R.M.5
-
33
-
-
84867913331
-
Histone deacetylase inhibitors stimulate dedifferentiation of human breast cancer cells through WNT/beta-catenin signaling
-
Debeb BG, Lacerda L, Xu W, Larson R, Solley T, Atkinson R, et al. Histone deacetylase inhibitors stimulate dedifferentiation of human breast cancer cells through WNT/beta-catenin signaling. Stem Cells 2012;30:2366-77.
-
(2012)
Stem Cells
, vol.30
, pp. 2366-2377
-
-
Debeb, B.G.1
Lacerda, L.2
Xu, W.3
Larson, R.4
Solley, T.5
Atkinson, R.6
|