E-cadherin promotor methylation and mutation are inversely related to motility capacity of breast cancer cells

Breast Cancer Research and Treatment

Volumn 136, Issue 2, 2012, Pages 365-377

  Van Horssen, Remco ^a,b   Hollestelle, Antoinette ^c   Rens, Joost A P Rens ^a   Eggermont, Alexander M M ^a,d   Schutte, Mieke ^c,e   Hagen, Timo L M Ten ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^d INSTITUT GUSTAVE ROUSSY   (France)

^e Lorentz Center   (Netherlands)

Author keywords

Cell migration; E cadherin; Mutation; Promotor hypermethylation

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBRONECTIN; UVOMORULIN;

ARTICLE; BARRIER MIGRATION ASSAY; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL ASSAY; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL STRAIN BT549; CELL STRAIN CAMA 1; CELL STRAIN MCF 7; CELL STRAIN MDA MB 231; CELL STRAIN MPE600; CELL STRAIN SK BR 3; CELL STRAIN SUM159PT; CELL STRAIN SUM52PE; CELL STRAIN T47D; COMPARATIVE STUDY; CONTROLLED STUDY; DNA METHYLATION; GENE INACTIVATION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; METASTASIS; MICROSCOPY; PRIORITY JOURNAL; PROMOTER REGION; TIME LAPSE IMAGING; TUMOR SUPPRESSOR GENE; TUMOR SUPPRESSOR GENE E CADHERIN;

BREAST NEOPLASMS; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; DNA METHYLATION; FEMALE; HUMANS; MCF-7 CELLS; MUTATION; PROMOTER REGIONS, GENETIC;

EID: 84868208585     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-012-2261-8     Document Type: Article

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