A New Mouse Model for the Study of Human Breast Cancer Metastasis

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Iorns, Elizabeth ^a,c   Drews Elger, Katherine ^a   Ward, Toby M ^b   Dean, Sonja ^a   Clarke, Jennifer ^a   Berry, Deborah ^d   Ashry, Dorraya El ^a   Lippman, Marc ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b STANFORD CANCER INSTITUTE   (United States)

^c Science Exchange Inc   (United States)

^d GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST METASTASIS; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MDA MB 231 GENE; MDA MB 436 GENE; MOUSE; NONHUMAN; PRIMARY TUMOR; TUMOR GENE; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED NOD; MICE, SCID; NEOPLASM TRANSPLANTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TRANSCRIPTOME;

MUS;

EID: 84868295693     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047995     Document Type: Article

References (21)

1. Jemal A, Siegel R, Xu J, Ward E, (2010) Cancer statistics, 2010. CA Cancer J Clin 60: 277-300.
2. Nguyen DX, Bos PD, Massagué J, (2009) Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 9: 274-84.
3. Price JE, (1996) Metastasis from human breast cancer cell lines. Breast Cancer Res Treat 39: 93-102.
4. Francia G, Cruz-Munoz W, Man S, Xu P, Kerbel RS, (2011) Mouse models of advanced spontaneous metastasis for experimental therapeutics. Nat Rev Cancer 11: 135-41.
5. Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, et al. (2005) Genes that mediate breast cancer metastasis to lung. Nature 436: 518-24.
6. Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, et al. (2003) A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3: 537-49.
7. Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, et al. (2005) Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol 174: 6477-89.
8. Lee TH, Seng S, Sekine M, Hinton C, Fu Y, et al. (2007) Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med 4: e186.
9. Lasfargues EY, Coutinho WG, Redfield ES, (1978) Isolation of two human tumor epithelial cell lines from solid breast carcinomas. J Natl Cancer Inst 61: 967-78.
10. Bayliss J, Hilger A, Vishnu P, Diehl K, El-Ashry D, (2007) Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response. Clin Cancer Res 13: 7029-36.
11. Kuperwasser C, Dessain S, Bierbaum BE, Garnet D, Sperandio K, et al. (2005) A mouse model of human breast cancer metastasis to human bone. Cancer Res 65: 6130-8.
12. Prensner JR, Chinnaiyan AM, (2011) The emergence of lncRNAs in cancer biology. Cancer Discov 1: 391-407.
13. Carvalho I, Milanezi F, Martins A, Reis RM, Schmitt F, (2005) Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression. Breast Cancer Res 7: R788-95.
14. Seymour L, Dajee D, Bezwoda WR, (1993) Tissue platelet derived-growth factor (PDGF) predicts for shortened survival and treatment failure in advanced breast cancer. Breast Cancer Res Treat 26: 247-52.
15. Seymour L, Bezwoda WR, (1994) Positive immunostaining for platelet derived growth factor (PDGF) is an adverse prognostic factor in patients with advanced breast cancer. Breast Cancer Res Treat 32: 229-33.
16. Cao R, Björndahl MA, Religa P, Clasper S, Garvin S, et al. (2004) PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis. Cancer Cell 6: 333-45.
17. Wang F, Yang YZ, Shi CZ, Zhang P, Moyer MP, et al. (2012) UHRF1 Promotes Cell Growth and Metastasis Through Repression of p16(ink4a) in Colorectal Cancer. Ann Surg Oncol 19: 2753-62.
18. Li XL, Xu JH, Nie JH, Fan SJ, (2012) Exogenous expression of UHRF1 promotes proliferation and metastasis of breast cancer cells. Oncol Rep 28: 375-83.
19. Driouch K, Lidereau R, (2000) Molecular analyses of human breast cancer metastasis: genetic markers of progression. Breast Cancer Res 2: P7.01.
20. Fang WB, Jokar I, Chytil A, Moses HL, Abel T, et al. (2011) Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression. Clin Exp Metastasis 28: 351-66.
21. Chiu KH, Chang YH, Wu YS, Lee SH, Liao PC, (2011) Quantitative secretome analysis reveals that COL6A1 is a metastasis-associated protein using stacking gel-aided purification combined with iTRAQ labeling. J Proteome Res 10: 1110-25.