Screening for small-molecule modulators of long noncoding RNA-protein interactions using alphascreen

Journal of Biomolecular Screening

Volumn 20, Issue 9, 2015, Pages 1132-1141

  Pedram Fatemi, Roya ^a   Salah Uddin, Sultan ^a   Modarresi, Farzaneh ^a   Khoury, Nathalie ^a   Wahlestedt, Claes ^a   Faghihi, Mohammad Ali ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

AlphaScreen; brain derived neurotrophic factor (BDNF); brain derived neurotrophic factor antisense (BDNFAS); Enhancer of zeste homolog 2 (EZH2); epigenetic enzyme; hox transcript antisense RNA (HOTAIR); long noncoding RNA; natural antisense transcript; noncoding RNA; RNA protein interaction

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; COMPLEMENTARY RNA; ELLIPTICINE; HOX PROTEIN; LONG UNTRANSLATED RNA; TRANSCRIPTION FACTOR EZH2; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN; ELLIPTICINE DERIVATIVE; EZH2 PROTEIN, HUMAN; HOTAIR LONG UNTRANSLATED RNA, HUMAN; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN BINDING;

ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; FEASIBILITY STUDY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN RNA BINDING; TRANSCRIPTION REGULATION; UPREGULATION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HEK293 CELL LINE; PRECLINICAL STUDY; RNA INTERFERENCE;

BRAIN-DERIVED NEUROTROPHIC FACTOR; DRUG EVALUATION, PRECLINICAL; ELLIPTICINES; ENHANCER OF ZESTE HOMOLOG 2 PROTEIN; GENE EXPRESSION; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN BINDING; RNA INTERFERENCE; RNA, LONG NONCODING;

EID: 84942109693     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057115594187     Document Type: Article

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