메뉴 건너뛰기




Volumn 13, Issue 9, 2015, Pages 673-679

Proteomic analysis of hepatocellular carcinoma HepG2 cells treated with platycodin D

Author keywords

2 D DIGE; HepG2; Platycodin D; Proteome

Indexed keywords

40S RIBOSOMAL PROTEIN S12; ANTINEOPLASTIC AGENT; ATP SYNTHASE SUBUNIT D; BARRIER TO AUTOINTEGRATION FACTOR; CELL PROTEIN; COILED COIL DOMIAINING 40 PROTEIN; DELTA(3,5)DELTA(2,4)DIENOYL COA ISOMERASE; ENDOPLASMIC RETICULUM RESIDENT PROTEIN 29; GALECTIN 1; HEAT SHOCK PROTEIN 27; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H; KERATIN TYPE 1 CYTOSKELETAL 9 PROTEIN; KERATIN TYPE II CYTOSKETAL 1 PROTEIN; MYOSIN LIGHT POLYPEPTIDE 6; PLATYCODIN D; PROHIBITIN; PROLIFERATION ASSOCIATED PROTEIN 2G4; PROTEOME; RETICULOCALBIN 1; RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1; SAPONIN DERIVATIVE; SUCCINYL COA 3 KETOACID COENZYME A TRANSFERASE 1; TRITERPENOID; TROPOMYOSIN ALPHA 3 CHAIN PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN 175; PLANT EXTRACT; SAPONIN; TRITERPENE;

EID: 84942103341     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(15)30065-0     Document Type: Article
Times cited : (24)

References (36)
  • 1
    • 14644424029 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-kappaB activation in RAW 264.7 cells [J]
    • Ahn KS, Noh EJ, Zhao HL, et al. Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-kappaB activation in RAW 264.7 cells [J]. Life Sci 2005, 76(20):2315-2328.
    • (2005) Life Sci , vol.76 , Issue.20 , pp. 2315-2328
    • Ahn, K.S.1    Noh, E.J.2    Zhao, H.L.3
  • 2
    • 0034743436 scopus 로고    scopus 로고
    • Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum [J]
    • Kim YP, Lee EB, Kim SY, et al. Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum [J]. Planta Med 2001, 67(4):362-364.
    • (2001) Planta Med , vol.67 , Issue.4 , pp. 362-364
    • Kim, Y.P.1    Lee, E.B.2    Kim, S.Y.3
  • 3
    • 84864919614 scopus 로고    scopus 로고
    • Anti-atherosclerotic activity of platycodin D derived from roots of Platycodon grandiflorum in human endothelial cells [J]
    • Wu JT, Yang GW, Zhu WX, et al. Anti-atherosclerotic activity of platycodin D derived from roots of Platycodon grandiflorum in human endothelial cells [J]. Bio Pharm Bull 2012, 35(8):1216-1221.
    • (2012) Bio Pharm Bull , vol.35 , Issue.8 , pp. 1216-1221
    • Wu, J.T.1    Yang, G.W.2    Zhu, W.X.3
  • 4
    • 0036322011 scopus 로고    scopus 로고
    • Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice [J]
    • Han LK, Zheng YN, Xu BJ, et al. Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice [J]. J Nutr 2002, 132(8):2241-2245.
    • (2002) J Nutr , vol.132 , Issue.8 , pp. 2241-2245
    • Han, L.K.1    Zheng, Y.N.2    Xu, B.J.3
  • 5
    • 77953884088 scopus 로고    scopus 로고
    • Platycodin D inhibits adipogenesis of 3T3-L1 cells by modulating Kruppel-like factor 2 and peroxisome proliferator-activated receptor gamma [J]
    • Lee H, Kang R, Kim YS, et al. Platycodin D inhibits adipogenesis of 3T3-L1 cells by modulating Kruppel-like factor 2 and peroxisome proliferator-activated receptor gamma [J]. Phytother Res 2010, 24(Suppl 2):S161-S167.
    • (2010) Phytother Res , vol.24 , pp. S161-S167
    • Lee, H.1    Kang, R.2    Kim, Y.S.3
  • 6
    • 50949087401 scopus 로고    scopus 로고
    • Platycodin D2 is a potential less hemolytic saponin adjuvant eliciting Th1 and Th2 immune responses [J]
    • Xie Y, Deng W, Sun H, et al. Platycodin D2 is a potential less hemolytic saponin adjuvant eliciting Th1 and Th2 immune responses [J]. Int Immunopharmacol 2008, 8(8):1143-1150.
    • (2008) Int Immunopharmacol , vol.8 , Issue.8 , pp. 1143-1150
    • Xie, Y.1    Deng, W.2    Sun, H.3
  • 7
    • 0036748248 scopus 로고    scopus 로고
    • Antinociceptive mechanisms of platycodin D administered intracerebroventricularly in the mouse [J]
    • Choi SS, Han EJ, Lee TH, et al. Antinociceptive mechanisms of platycodin D administered intracerebroventricularly in the mouse [J]. Planta Med 2002, 68(9):794-798.
    • (2002) Planta Med , vol.68 , Issue.9 , pp. 794-798
    • Choi, S.S.1    Han, E.J.2    Lee, T.H.3
  • 8
    • 21344449760 scopus 로고    scopus 로고
    • Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines [J]
    • Kim YS, Kim JS, Choi SU, et al. Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines [J]. Planta Med 2005, 71(6):566-568.
    • (2005) Planta Med , vol.71 , Issue.6 , pp. 566-568
    • Kim, Y.S.1    Kim, J.S.2    Choi, S.U.3
  • 9
    • 43049141875 scopus 로고    scopus 로고
    • Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells [J]
    • Kim MO, Moon DO, Choi YH, et al. Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells [J]. Int J Cancer 2008, 122(12):2674-2681.
    • (2008) Int J Cancer , vol.122 , Issue.12 , pp. 2674-2681
    • Kim, M.O.1    Moon, D.O.2    Choi, Y.H.3
  • 10
    • 59249089850 scopus 로고    scopus 로고
    • Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells [J]
    • Shin DY, Kim GY, Li W, et al. Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells [J]. Biomed Pharmacother 2009, 63(2):86-94.
    • (2009) Biomed Pharmacother , vol.63 , Issue.2 , pp. 86-94
    • Shin, D.Y.1    Kim, G.Y.2    Li, W.3
  • 11
    • 78650216101 scopus 로고    scopus 로고
    • Antiproliferative effects of saponins from the roots of Platycodon grandiflorum on cultured human tumor cells [J]
    • Choi YH, Yoo DS, Cha MR, et al. Antiproliferative effects of saponins from the roots of Platycodon grandiflorum on cultured human tumor cells [J]. J Nat Prod 2010, 73(11):1863-1867.
    • (2010) J Nat Prod , vol.73 , Issue.11 , pp. 1863-1867
    • Choi, Y.H.1    Yoo, D.S.2    Cha, M.R.3
  • 12
    • 77957363800 scopus 로고    scopus 로고
    • Platycodin D induces apoptosis in MCF-7 human breast cancer cells [J]
    • Yu JS, Kim AK Platycodin D induces apoptosis in MCF-7 human breast cancer cells [J]. J Med Food 2010, 13(2):298-305.
    • (2010) J Med Food , vol.13 , Issue.2 , pp. 298-305
    • Yu, J.S.1    Kim, A.K.2
  • 13
    • 39149121841 scopus 로고    scopus 로고
    • Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells [J]
    • Kim MO, Moon DO, Choi YH, et al. Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells [J]. Cancer Lett 2008, 261(1):98-107.
    • (2008) Cancer Lett , vol.261 , Issue.1 , pp. 98-107
    • Kim, M.O.1    Moon, D.O.2    Choi, Y.H.3
  • 14
    • 84897011458 scopus 로고    scopus 로고
    • Platycodin D induces apoptosis, and inhibits adhesion, migration and invasion in HepG2 hepatocellular carcinoma cells [J]
    • Li T, Xu WS, Wu GS, et al. Platycodin D induces apoptosis, and inhibits adhesion, migration and invasion in HepG2 hepatocellular carcinoma cells [J]. Asian Pac J Cancer Prev 2014, 15(4):1745-1749.
    • (2014) Asian Pac J Cancer Prev , vol.15 , Issue.4 , pp. 1745-1749
    • Li, T.1    Xu, W.S.2    Wu, G.S.3
  • 15
    • 84903540897 scopus 로고    scopus 로고
    • Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells [J]
    • Tang ZH, Li T, Gao HW, et al. Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells [J]. Chin Med 2014, 9:16.
    • (2014) Chin Med , vol.9 , pp. 16
    • Tang, Z.H.1    Li, T.2    Gao, H.W.3
  • 16
    • 84872746194 scopus 로고    scopus 로고
    • Platycodin D induces anoikis and caspase-mediated apoptosis via p38 MAPK in AGS human gastric cancer cells [J]
    • Chun J, Joo EJ, Kang M, et al. Platycodin D induces anoikis and caspase-mediated apoptosis via p38 MAPK in AGS human gastric cancer cells [J]. J Cell Biochem 2013, 114(2):456-470.
    • (2013) J Cell Biochem , vol.114 , Issue.2 , pp. 456-470
    • Chun, J.1    Joo, E.J.2    Kang, M.3
  • 17
    • 84882297137 scopus 로고    scopus 로고
    • Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways [J]
    • Chun J, Kim YS Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways [J]. Chem Biol Interact 2013, 205(3):212-221.
    • (2013) Chem Biol Interact , vol.205 , Issue.3 , pp. 212-221
    • Chun, J.1    Kim, Y.S.2
  • 18
    • 84864587755 scopus 로고    scopus 로고
    • Platycodin D induces reactive oxygen species-mediated apoptosis signal-regulating kinase 1 activation and endoplasmic reticulum stress response in human breast cancer cells [J]
    • Yu JS, Kim AK Platycodin D induces reactive oxygen species-mediated apoptosis signal-regulating kinase 1 activation and endoplasmic reticulum stress response in human breast cancer cells [J]. J Med Food 2012, 15(8):691-699.
    • (2012) J Med Food , vol.15 , Issue.8 , pp. 691-699
    • Yu, J.S.1    Kim, A.K.2
  • 19
    • 84856035765 scopus 로고    scopus 로고
    • The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells [J]
    • Lu JJ, Chen SM, Zhang XW, et al. The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells [J]. Invest New Drugs 2011, 29(6):1276-1283.
    • (2011) Invest New Drugs , vol.29 , Issue.6 , pp. 1276-1283
    • Lu, J.J.1    Chen, S.M.2    Zhang, X.W.3
  • 20
    • 43849085358 scopus 로고    scopus 로고
    • Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network [J]
    • Yue QX, Cao ZW, Guan SH, et al. Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network [J]. Mol Cell Proteomics 2008, 7(5):949-961.
    • (2008) Mol Cell Proteomics , vol.7 , Issue.5 , pp. 949-961
    • Yue, Q.X.1    Cao, Z.W.2    Guan, S.H.3
  • 21
    • 0032563335 scopus 로고    scopus 로고
    • Oligomerization properties of ERp29, an endoplasmic reticulum stress protein [J]
    • Mkrtchian S, Baryshev M, Matvijenko O, et al. Oligomerization properties of ERp29, an endoplasmic reticulum stress protein [J]. FEBS Lett 1998, 431(3):322-326.
    • (1998) FEBS Lett , vol.431 , Issue.3 , pp. 322-326
    • Mkrtchian, S.1    Baryshev, M.2    Matvijenko, O.3
  • 22
    • 70350625338 scopus 로고    scopus 로고
    • Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal-epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells [J]
    • Bambang IF, Xu S, Zhou J, et al. Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal-epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells [J]. Lab Invest 2009, 89(11):1229-1242.
    • (2009) Lab Invest , vol.89 , Issue.11 , pp. 1229-1242
    • Bambang, I.F.1    Xu, S.2    Zhou, J.3
  • 23
    • 0034054236 scopus 로고    scopus 로고
    • Ectopic expression of the ErbB-3 binding protein ebp1 inhibits growth and induces differentiation of human breast cancer cell lines [J]
    • Lessor TJ, Yoo JY, Xia X, et al. Ectopic expression of the ErbB-3 binding protein ebp1 inhibits growth and induces differentiation of human breast cancer cell lines [J]. J Cell Physiol 2000, 183(3):321-329.
    • (2000) J Cell Physiol , vol.183 , Issue.3 , pp. 321-329
    • Lessor, T.J.1    Yoo, J.Y.2    Xia, X.3
  • 24
    • 79251519290 scopus 로고    scopus 로고
    • The ErbB3 binding protein EBP1 regulates ErbB2 protein levels and tamoxifen sensitivity in breast cancer cells [J]
    • Lu Y, Zhou H, Chen W, et al. The ErbB3 binding protein EBP1 regulates ErbB2 protein levels and tamoxifen sensitivity in breast cancer cells [J]. Breast Cancer Res Treat 2011, 126(1):27-36.
    • (2011) Breast Cancer Res Treat , vol.126 , Issue.1 , pp. 27-36
    • Lu, Y.1    Zhou, H.2    Chen, W.3
  • 25
    • 66849099679 scopus 로고    scopus 로고
    • Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication [J]
    • Rizwani W, Alexandrow M, Chellappan S Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication [J]. Cell Cycle 2009, 8(10):1621-1629.
    • (2009) Cell Cycle , vol.8 , Issue.10 , pp. 1621-1629
    • Rizwani, W.1    Alexandrow, M.2    Chellappan, S.3
  • 26
    • 81555217982 scopus 로고    scopus 로고
    • Involvement of prohibitin upregulation in abrin-triggered apoptosis [J]
    • Liu YH, Peck K, Lin JY Involvement of prohibitin upregulation in abrin-triggered apoptosis [J]. Evid Based Complement Alternat Med 2012, 2012:605154.
    • (2012) Evid Based Complement Alternat Med , vol.2012 , pp. 605154
    • Liu, Y.H.1    Peck, K.2    Lin, J.Y.3
  • 27
    • 84876004060 scopus 로고    scopus 로고
    • RPS12-specific shRNA inhibits the proliferation, migration of BGC823 gastric cancer cells with S100A4 as a downstream effector [J]
    • Chen D, Zhang R, Shen W, et al. RPS12-specific shRNA inhibits the proliferation, migration of BGC823 gastric cancer cells with S100A4 as a downstream effector [J]. Int J Oncol 2013, 42(5):1763-1769.
    • (2013) Int J Oncol , vol.42 , Issue.5 , pp. 1763-1769
    • Chen, D.1    Zhang, R.2    Shen, W.3
  • 28
    • 77957761380 scopus 로고    scopus 로고
    • Proteomic analysis of anti-tumor effects by tetrandrine treatment in HepG2 cells [J]
    • Cheng Z, Wang K, Wei J, et al. Proteomic analysis of anti-tumor effects by tetrandrine treatment in HepG2 cells [J]. Phytomedicine 2010, 17(13):1000-1005.
    • (2010) Phytomedicine , vol.17 , Issue.13 , pp. 1000-1005
    • Cheng, Z.1    Wang, K.2    Wei, J.3
  • 29
    • 0032545640 scopus 로고    scopus 로고
    • Modulation of galectin-1 content in human head and neck squamous carcinoma cells by sodium butyrate [J]
    • Gillenwater A, Xu XC, Estrov Y, et al. Modulation of galectin-1 content in human head and neck squamous carcinoma cells by sodium butyrate [J]. Int J Cancer 1998, 75(2):217-224.
    • (1998) Int J Cancer , vol.75 , Issue.2 , pp. 217-224
    • Gillenwater, A.1    Xu, X.C.2    Estrov, Y.3
  • 30
    • 84870695698 scopus 로고    scopus 로고
    • Galectin 1 expression is associated with tumor invasion and metastasis in stage IB to IIA cervical cancer [J]
    • Kim HJ, Do IG, Jeon HK, et al. Galectin 1 expression is associated with tumor invasion and metastasis in stage IB to IIA cervical cancer [J]. Hum Pathol 2013, 44(1):62-68.
    • (2013) Hum Pathol , vol.44 , Issue.1 , pp. 62-68
    • Kim, H.J.1    Do, I.G.2    Jeon, H.K.3
  • 31
    • 77958581453 scopus 로고    scopus 로고
    • Identification of up- and down-regulated proteins in gemcitabine-resistant pancreatic cancer cells using two-dimensional gel electrophoresis and mass spectrometry [J]
    • Kuramitsu Y, Taba K, Ryozawa S, et al. Identification of up- and down-regulated proteins in gemcitabine-resistant pancreatic cancer cells using two-dimensional gel electrophoresis and mass spectrometry [J]. Anticancer Res 2010, 30(9):3367-3372.
    • (2010) Anticancer Res , vol.30 , Issue.9 , pp. 3367-3372
    • Kuramitsu, Y.1    Taba, K.2    Ryozawa, S.3
  • 32
    • 83555163925 scopus 로고    scopus 로고
    • Characterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line [J]
    • Lu JJ, Chen SM, Ding J, et al. Characterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line [J]. Mol Cell Biochem 2012, 360(1-2):329-337.
    • (2012) Mol Cell Biochem , vol.360 , Issue.1-2 , pp. 329-337
    • Lu, J.J.1    Chen, S.M.2    Ding, J.3
  • 33
    • 33846821658 scopus 로고    scopus 로고
    • Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells [J]
    • Kamada M, So A, Muramaki M, et al. Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells [J]. Mol Cancer Ther 2007, 6(1):299-308.
    • (2007) Mol Cancer Ther , vol.6 , Issue.1 , pp. 299-308
    • Kamada, M.1    So, A.2    Muramaki, M.3
  • 34
    • 84878322096 scopus 로고    scopus 로고
    • Proteomic profiling reveals that resveratrol inhibits HSP27 expression and sensitizes breast cancer cells to doxorubicin therapy [J]
    • Diaz-Chavez J, Fonseca-Sanchez MA, Arechaga-Ocampo E, et al. Proteomic profiling reveals that resveratrol inhibits HSP27 expression and sensitizes breast cancer cells to doxorubicin therapy [J]. PLoS One 2013, 8(5):e64378.
    • (2013) PLoS One , vol.8 , Issue.5 , pp. e64378
    • Diaz-Chavez, J.1    Fonseca-Sanchez, M.A.2    Arechaga-Ocampo, E.3
  • 35
    • 84866305839 scopus 로고    scopus 로고
    • Inhibiting ERp29 expression enhances radiosensitivity in human nasopharyngeal carcinoma cell lines [J]
    • Qi L, Wu P, Zhang X, et al. Inhibiting ERp29 expression enhances radiosensitivity in human nasopharyngeal carcinoma cell lines [J]. Med Oncol 2012, 29(2):721-728.
    • (2012) Med Oncol , vol.29 , Issue.2 , pp. 721-728
    • Qi, L.1    Wu, P.2    Zhang, X.3
  • 36
    • 78149412690 scopus 로고    scopus 로고
    • Over-expression of ERp29 attenuates doxorubicin-induced cell apoptosis through up-regulation of Hsp27 in breast cancer cells [J]
    • Zhang D, Putti TC Over-expression of ERp29 attenuates doxorubicin-induced cell apoptosis through up-regulation of Hsp27 in breast cancer cells [J]. Exp Cell Res 2010, 316(20):3522-3531.
    • (2010) Exp Cell Res , vol.316 , Issue.20 , pp. 3522-3531
    • Zhang, D.1    Putti, T.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.