Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas

Endocrine-Related Cancer

Volumn 22, Issue 5, 2015, Pages 735-744

  Akerström, Tobias ^a   Willenberg, Holger Sven ^b   Cupisti, Kenko ^c   Ip, Julian ^d   Backman, Samuel ^a   Moser, Ana ^e   Maharjan, Rajani ^a   Robinson, Bruce ^d   Iwen, K Alexander ^e   Dralle, Henning ^f   Volpe, Cristina D ^g   Bäckdahl, Martin ^g   Botling, Johan ^a   Stalberg, Peter ^a   Westin, Gunnar ^a   Walz, Martin K ^h   Lehnert, Hendrik ^e   Sidhu, Stan ^d   Zedenius, Jan ^g   Björklund, Peyman ^a   Hellman, Per ^a   more..

^a UPPSALA UNIVERSITY   (Sweden)

^b ROSTOCK UNIVERSITY MEDICAL CENTER   (Germany)

^c UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^d UNIVERSITY OF SYDNEY   (Australia)

^e UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^f MARTIN LUTHER UNIVERSITÄT HALLE WITTENBERG   (Germany)

^g KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^h KLINIKEN ESSEN MITTE   (Germany)

Author keywords

Aldosterone producing adenoma; ATP1A1; CACNA1D; KCNJ5; Primary aldosteronism

Indexed keywords

ALDOSTERONE; ALDOSTERONE SYNTHASE; CALCIUM ION; MESSENGER RNA; TRANSCRIPTOME; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ATP1A1 PROTEIN, HUMAN; ATP2B3 PROTEIN, HUMAN; CACNA1D PROTEIN, HUMAN; CALCIUM CHANNEL L TYPE; PLASMA MEMBRANE CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; TUMOR MARKER;

ADULT; AGE; ALDOSTERONE BLOOD LEVEL; ARTICLE; ATP1A1 GENE; ATP2B3 GENE; CACNA1D GENE; CALCIUM CELL LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; GENE; HUMAN; IMMUNOHISTOCHEMISTRY; KCNJ5 GENE; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; MUTATIONAL ANALYSIS; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIMARY HYPERALDOSTERONISM; PRINCIPAL COMPONENT ANALYSIS; SOMATIC MUTATION; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; TUMOR VOLUME; UPREGULATION; ADRENAL CORTEX ADENOMA; ADRENAL CORTEX TUMOR; AGED; CANCER STAGING; ENZYME IMMUNOASSAY; FOLLOW UP; GENE EXPRESSION PROFILING; GENETICS; HYPERALDOSTERONISM; METABOLISM; MIDDLE AGED; MUTATION; PATHOLOGY; PROGNOSIS; VERY ELDERLY;

ADRENAL CORTEX NEOPLASMS; ADRENOCORTICAL ADENOMA; ADULT; AGED; AGED, 80 AND OVER; ALDOSTERONE; BIOMARKERS, TUMOR; CALCIUM CHANNELS, L-TYPE; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION PROFILING; HUMANS; HYPERALDOSTERONISM; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; MUTATION; NEOPLASM STAGING; PHENOTYPE; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; POLYMERASE CHAIN REACTION; PROGNOSIS; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84942083490     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1530/ERC-15-0321     Document Type: Article

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