The development of depression-like behavior is consolidated by IL-6-induced activation of locus coeruleus neurons and IL-1β-induced elevated leptin levels in mice

Psychopharmacology

Volumn 233, Issue 9, 2016, Pages 1725-1737

  Kurosawa, Natsuki ^a   Shimizu, Koh ^a   Seki, Kenjiro ^a  

^a OHU UNIVERSITY   (Japan)

Author keywords

Cytokine hypothesis; Depression; Intracerebroventricular administration; Leptin; Noradrenaline; Phenylephrine; Prazosin

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEPTIN; LIPOPOLYSACCHARIDE; PHENYLEPHRINE; PRAZOSIN; PROTEIN C FOS; RECOMBINANT LEPTIN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE 3 MONOOXYGENASE; INTERLEUKIN-6, MOUSE; TUMOR NECROSIS FACTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; CONTROLLED STUDY; CYTOKINE BLOOD LEVEL; DEPRESSION; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FORCED SWIM TEST; HORMONE BLOOD LEVEL; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; LEPTIN BLOOD LEVEL; LOCUS CERULEUS; MALE; MOUSE; NERVE CELL STIMULATION; NONHUMAN; NORADRENERGIC NERVE CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SUCROSE PREFERENCE TEST; TAIL SUSPENSION TEST; ANHEDONIA; ANIMAL; ANIMAL BEHAVIOR; DRUG EFFECTS; IMMOBILIZATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; NERVE CELL; PSYCHOLOGY; SWIMMING;

ANHEDONIA; ANIMALS; BEHAVIOR, ANIMAL; DEPRESSION; HINDLIMB SUSPENSION; INJECTIONS, INTRAVENTRICULAR; INTERLEUKIN-1BETA; INTERLEUKIN-6; LEPTIN; LOCUS COERULEUS; MALE; MICE; NEURONS; RECEPTORS, ADRENERGIC, ALPHA-1; SWIMMING; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84942065724     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-015-4084-x     Document Type: Article

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