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Volumn 72, Issue 4, 1996, Pages 989-997

Activation of serotonergic and noradrenergic neurotransmission in the rat hippocampus after peripheral administration of bacterial endotoxin: Involvement of the cyclo-oxygenase pathway

Author keywords

Behavior; In vivo microdialysis; Indomethacin; Lipopolysaccharide; Preoptic area; Prostaglandins

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ARACHIDONIC ACID; INDOMETACIN; LIPOPOLYSACCHARIDE; NORADRENALIN; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; SEROTONIN; 4 HYDROXY 3 METHOXYPHENYLETHYLENE GLYCOL; 5 HYDROXYINDOLEACETIC ACID; ENDOTOXIN; PROSTAGLANDIN;

EID: 0029666463     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(95)00604-4     Document Type: Article
Times cited : (82)

References (49)
  • 1
    • 0026462431 scopus 로고
    • Brain interleukin-1 gene expression induced by peripheral lipopolysaccharide administration
    • Ban E., Haour F. and Lenstra R. (1992) Brain interleukin-1 gene expression induced by peripheral lipopolysaccharide administration. Cytokine 4, 48-54.
    • (1992) Cytokine , vol.4 , pp. 48-54
    • Ban, E.1    Haour, F.2    Lenstra, R.3
  • 2
    • 0026547085 scopus 로고
    • Immune-neuroendocrine circuits: Integrative role of cytokines
    • Besedovsky H. O. and Del Rey A. (1992) Immune-neuroendocrine circuits: integrative role of cytokines. Front. Neuroendocr. 13, 61-94.
    • (1992) Front. Neuroendocr. , vol.13 , pp. 61-94
    • Besedovsky, H.O.1    Del Rey, A.2
  • 3
    • 0028041236 scopus 로고
    • Systemic interleukin-1 induces early and late patterns of c-fos mRNA expression in brain
    • Brady L. S., Lynn A. B., Herkenham M. and Gottesfeld Z. (1994) Systemic interleukin-1 induces early and late patterns of c-fos mRNA expression in brain. J. Neurosci. 14, 4951-4964.
    • (1994) J. Neurosci. , vol.14 , pp. 4951-4964
    • Brady, L.S.1    Lynn, A.B.2    Herkenham, M.3    Gottesfeld, Z.4
  • 4
    • 0000187530 scopus 로고
    • Behavioural effects of cytokines
    • (eds Rothwell N. and Dantzer R.), Pergamon Press, Oxford
    • Dantzer R., Bluthe R. M., Kent S. and Kelley K. W. (1992) Behavioural effects of cytokines. In Interleukin-1 in the Brain (eds Rothwell N. and Dantzer R.), pp. 135-150. Pergamon Press, Oxford.
    • (1992) Interleukin-1 in the Brain , pp. 135-150
    • Dantzer, R.1    Bluthe, R.M.2    Kent, S.3    Kelley, K.W.4
  • 5
    • 0026763167 scopus 로고
    • Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: Comparison with interleukin-1
    • Dunn A. J. (1992) Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: comparison with interleukin-1. J. Pharmac. exp. Ther. 261, 964-969.
    • (1992) J. Pharmac. Exp. Ther. , vol.261 , pp. 964-969
    • Dunn, A.J.1
  • 6
    • 0026446814 scopus 로고
    • The role of interleukin-1 and tumour necrosis factor α in the neurochemical and neuroendocrine responses to endotoxin
    • Dunn A. J. (1992) The role of interleukin-1 and tumour necrosis factor α in the neurochemical and neuroendocrine responses to endotoxin. Brain Res. Bull. 29, 807-812.
    • (1992) Brain Res. Bull. , vol.29 , pp. 807-812
    • Dunn, A.J.1
  • 7
    • 0027333502 scopus 로고
    • Induction of Fos-like immunoreactivity in the rat brain following Pasteurella multocida endotoxin administration
    • Elmquist J. K., Ackermann M. R., Register K. B., Rimler R. B., Ross L. R. and Jacobson C. D. (1993) Induction of Fos-like immunoreactivity in the rat brain following Pasteurella multocida endotoxin administration. Endocrinology 133, 3054-3057.
    • (1993) Endocrinology , vol.133 , pp. 3054-3057
    • Elmquist, J.K.1    Ackermann, M.R.2    Register, K.B.3    Rimler, R.B.4    Ross, L.R.5    Jacobson, C.D.6
  • 8
    • 0028125574 scopus 로고
    • A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons
    • Ericsson A., Kovács K. J. and Sawchenko P. E. (1994) A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons. J. Neurosci. 14, 897-913.
    • (1994) J. Neurosci. , vol.14 , pp. 897-913
    • Ericsson, A.1    Kovács, K.J.2    Sawchenko, P.E.3
  • 10
    • 0020555603 scopus 로고
    • The nucleus locus coeruleus: New evidence of anatomical and physiological specificity
    • Foote S. L., Bloom F. E. and Aston-Jones G. (1983) The nucleus locus coeruleus: new evidence of anatomical and physiological specificity. Physiol. Rev. 63, 844-914.
    • (1983) Physiol. Rev. , vol.63 , pp. 844-914
    • Foote, S.L.1    Bloom, F.E.2    Aston-Jones, G.3
  • 11
    • 0006023253 scopus 로고
    • Interleukin-1β activation of the central nervous system
    • (eds Rothwell N. and Dantzer R.), Pergamon Press, Oxford
    • Gottschall P. E., Komaki G. and Arimura A. (1992) Interleukin-1β activation of the central nervous system. In Interleukin-1 in the Brain (eds Rothwell N. and Dantzer R.), pp. 27-49. Pergamon Press, Oxford.
    • (1992) Interleukin-1 in the Brain , pp. 27-49
    • Gottschall, P.E.1    Komaki, G.2    Arimura, A.3
  • 12
    • 0024159821 scopus 로고
    • Biological basis of the behavior of sick animals
    • Hart B. L. (1988) Biological basis of the behavior of sick animals. Neurosci. Biobehav. Rev. 12, 123-137.
    • (1988) Neurosci. Biobehav. Rev. , vol.12 , pp. 123-137
    • Hart, B.L.1
  • 13
    • 0026515597 scopus 로고
    • Structure and function of the brain serotonin system
    • Jacobs B. L. and Azmitia E. C. (1992) Structure and function of the brain serotonin system. Physiol. Rev. 72, 165-229.
    • (1992) Physiol. Rev. , vol.72 , pp. 165-229
    • Jacobs, B.L.1    Azmitia, E.C.2
  • 14
    • 0024340439 scopus 로고
    • Hippocampal noradrenaline and serotonin release over 24 hours as measured by the dialysis technique in freely moving rats: Correlation to behavioral activity state, effect of handling and tail-pinch
    • Kalén P., Rosegren E., Lindvall O. and Björklund A. (1989) Hippocampal noradrenaline and serotonin release over 24 hours as measured by the dialysis technique in freely moving rats: correlation to behavioral activity state, effect of handling and tail-pinch. Eur. J. Neurosci. 1, 181-188.
    • (1989) Eur. J. Neurosci. , vol.1 , pp. 181-188
    • Kalén, P.1    Rosegren, E.2    Lindvall, O.3    Björklund, A.4
  • 15
    • 0027456714 scopus 로고
    • Role of nitric oxide in interleukin 2-induced corticotropin-releasing factor release from incubated hypothalami
    • Karanth S., Lyson K. and McCann S. M. (1993) Role of nitric oxide in interleukin 2-induced corticotropin-releasing factor release from incubated hypothalami. Proc. natn. Acad. Sci. U.S.A. 90, 3383-3387.
    • (1993) Proc. Natn. Acad. Sci. U.S.A. , vol.90 , pp. 3383-3387
    • Karanth, S.1    Lyson, K.2    McCann, S.M.3
  • 16
    • 0023921318 scopus 로고
    • Adrenocorticotropin release induced by recombinant human interleukin-1 in rats: Possible involvement of prostaglandin
    • Katsuura G., Gottschall P. E., Dahl R. R. and Arimura A. (1988) Adrenocorticotropin release induced by recombinant human interleukin-1 in rats: possible involvement of prostaglandin. Endocrinology 122, 1773-1779.
    • (1988) Endocrinology , vol.122 , pp. 1773-1779
    • Katsuura, G.1    Gottschall, P.E.2    Dahl, R.R.3    Arimura, A.4
  • 18
    • 0025960495 scopus 로고
    • Fever: Role of pyrogens and cryogens
    • Kluger M. J. (1991) Fever: role of pyrogens and cryogens. Physiol. Rev. 71, 93-127.
    • (1991) Physiol. Rev. , vol.71 , pp. 93-127
    • Kluger, M.J.1
  • 19
    • 0020000298 scopus 로고
    • The phenomenon of the acute phase response
    • Kushner I. (1982) The phenomenon of the acute phase response. Ann. N. Y. Acad. Sci. 389, 39-48.
    • (1982) Ann. N. Y. Acad. Sci. , vol.389 , pp. 39-48
    • Kushner, I.1
  • 20
    • 0028813430 scopus 로고
    • Endotoxin administration stimulates cerebral catecholamine release in freely moving rats as assessed by microdialysis
    • Lavicky J. and Dunn A. J. (1995) Endotoxin administration stimulates cerebral catecholamine release in freely moving rats as assessed by microdialysis. J. Neurosci. Res. 40, 407-413.
    • (1995) J. Neurosci. Res. , vol.40 , pp. 407-413
    • Lavicky, J.1    Dunn, A.J.2
  • 21
    • 0028092812 scopus 로고
    • Local administration of recombinant human interleukin-1β in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature
    • Linthorst A. C. E., Flachskamm C., Holsboer F. and Reul J. M. H. M. (1994) Local administration of recombinant human interleukin-1β in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature. Endocrinology 135, 520-532.
    • (1994) Endocrinology , vol.135 , pp. 520-532
    • Linthorst, A.C.E.1    Flachskamm, C.2    Holsboer, F.3    Reul, J.M.H.M.4
  • 22
    • 0028886115 scopus 로고
    • Intraperitoneal administration of bacterial endotoxin enhances noradrenergic neurotransmission in the rat preoptic area: Relationship with body temperature and hypothalamic-pituitary-adrenocortical axis activity
    • Linthorst A. C. E., Flachskamm C., Holsboer F. and Reul J. M. H. M. (1995) Intraperitoneal administration of bacterial endotoxin enhances noradrenergic neurotransmission in the rat preoptic area: relationship with body temperature and hypothalamic-pituitary-adrenocortical axis activity. Eur. J. Neurosci. 7, 2418-2430.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 2418-2430
    • Linthorst, A.C.E.1    Flachskamm, C.2    Holsboer, F.3    Reul, J.M.H.M.4
  • 23
    • 0028968980 scopus 로고
    • Effect of bacterial endotoxin and interleukin-1β on hippocampal serotonergic neurotransmission, behavioral activity, and free corticosterone levels: An in vivo microdialysis study
    • Linthorst A. C. E., Flachskamm C., Müller-Preuss P., Holsboer F. and Reul J. M. H. M. (1995) Effect of bacterial endotoxin and interleukin-1β on hippocampal serotonergic neurotransmission, behavioral activity, and free corticosterone levels: an in vivo microdialysis study. J. Neurosci. 15, 2920-2934.
    • (1995) J. Neurosci. , vol.15 , pp. 2920-2934
    • Linthorst, A.C.E.1    Flachskamm, C.2    Müller-Preuss, P.3    Holsboer, F.4    Reul, J.M.H.M.5
  • 24
    • 0028904546 scopus 로고
    • Modulation of norepinephrine release by serotonergic receptors in the rat hippocampus as measured by in vivo microdialysis
    • Matsumoto M., Yoshioka M., Togashi H., Tochihara M., Ikeda T. and Saito H. (1995) Modulation of norepinephrine release by serotonergic receptors in the rat hippocampus as measured by in vivo microdialysis. J. Pharmac. exp. Ther. 272, 1044-1051.
    • (1995) J. Pharmac. Exp. Ther. , vol.272 , pp. 1044-1051
    • Matsumoto, M.1    Yoshioka, M.2    Togashi, H.3    Tochihara, M.4    Ikeda, T.5    Saito, H.6
  • 25
    • 0025305846 scopus 로고
    • Increased biogenic amine release in mouse hypothalamus following immunological challenge: Antagonism by indomethacin
    • Mefford I. N. and Heyes M. P. (1990) Increased biogenic amine release in mouse hypothalamus following immunological challenge: antagonism by indomethacin. J. Neuroimmun. 27, 55-61.
    • (1990) J. Neuroimmun. , vol.27 , pp. 55-61
    • Mefford, I.N.1    Heyes, M.P.2
  • 26
    • 0028365824 scopus 로고
    • Expression of inducible nitric oxide synthase by neurones following exposure to endotoxin and cytokine
    • Minc-Golomb D., Tsafraty I. and Schwartz J. P. (1994) Expression of inducible nitric oxide synthase by neurones following exposure to endotoxin and cytokine. Br. J. Pharmac. 112, 720-722.
    • (1994) Br. J. Pharmac. , vol.112 , pp. 720-722
    • Minc-Golomb, D.1    Tsafraty, I.2    Schwartz, J.P.3
  • 27
    • 0027189927 scopus 로고
    • Systemic administration of interleukin-1 stimulates norepinephrine release in the paraventricular nucleus
    • MohanKumar P. S. and Quadri S. K. (1993) Systemic administration of interleukin-1 stimulates norepinephrine release in the paraventricular nucleus. Life Sci. 52, 1961-1967.
    • (1993) Life Sci. , vol.52 , pp. 1961-1967
    • Mohankumar, P.S.1    Quadri, S.K.2
  • 29
    • 0028335911 scopus 로고
    • Effects of long-term alpha-2 adrenergic antagonists and electroconvulsive treatments on the alpha-2 adrenoceptors modulating serotonin neurotransmission
    • Mongeau R., De Montigny C. and Blier P. (1994) Effects of long-term alpha-2 adrenergic antagonists and electroconvulsive treatments on the alpha-2 adrenoceptors modulating serotonin neurotransmission. J. Pharmac. exp. Ther. 269, 1152-1159.
    • (1994) J. Pharmac. Exp. Ther. , vol.269 , pp. 1152-1159
    • Mongeau, R.1    De Montigny, C.2    Blier, P.3
  • 30
    • 0024501798 scopus 로고
    • Possible involvement of prostaglandin E in development of ACTH response in rats induced by human recombinant interleukin-1
    • Morimoto A., Murakami N., Nakamori T., Sakata Y. and Watanabe T. (1989) Possible involvement of prostaglandin E in development of ACTH response in rats induced by human recombinant interleukin-1. J. Physiol., Lond. 411, 245-256.
    • (1989) J. Physiol., Lond. , vol.411 , pp. 245-256
    • Morimoto, A.1    Murakami, N.2    Nakamori, T.3    Sakata, Y.4    Watanabe, T.5
  • 31
    • 0028089288 scopus 로고
    • 2 stimulates cardiovascular function in anesthetized rats
    • 2 stimulates cardiovascular function in anesthetized rats. J. auton. nerv. Syst. 46, 199-205.
    • (1994) J. Auton. Nerv. Syst. , vol.46 , pp. 199-205
    • Osborne, P.G.1    Kurosawa, M.2
  • 32
    • 0028921409 scopus 로고
    • Stress-induced norepinephrine release in the hypothalamic paraventricular nucleus and pituitary-adrenocortical and sympathoadrenal activity: In vivo microdialysis study
    • Pacak K., Palkovits M., Kopin I. J. and Goldstein D. S. (1995) Stress-induced norepinephrine release in the hypothalamic paraventricular nucleus and pituitary-adrenocortical and sympathoadrenal activity: in vivo microdialysis study. Front. Neuroendocr. 16, 89-150.
    • (1995) Front. Neuroendocr. , vol.16 , pp. 89-150
    • Pacak, K.1    Palkovits, M.2    Kopin, I.J.3    Goldstein, D.S.4
  • 34
    • 0028314343 scopus 로고
    • Induction of interleukin-1 in various brain regions after peripheral and central injections of lipopolysaccharide
    • Quan N., Sundar S. K. and Weiss J. M. (1994) Induction of interleukin-1 in various brain regions after peripheral and central injections of lipopolysaccharide. J. Neuroimmun. 49, 125-134.
    • (1994) J. Neuroimmun. , vol.49 , pp. 125-134
    • Quan, N.1    Sundar, S.K.2    Weiss, J.M.3
  • 35
    • 0028111418 scopus 로고
    • IL-2 induces vasopressin release from the hypothalamus and the amygdala: Role of nitric oxide-mediated signaling
    • Raber J. and Bloom F. E. (1994) IL-2 induces vasopressin release from the hypothalamus and the amygdala: role of nitric oxide-mediated signaling. J. Neurosci. 14, 6187-6195.
    • (1994) J. Neurosci. , vol.14 , pp. 6187-6195
    • Raber, J.1    Bloom, F.E.2
  • 36
    • 0025818355 scopus 로고
    • Interleukin-1β decreases acetylcholine measured by microdialysis in the hippocampus of freely moving rats
    • Rada P., Mark G. P., Vitek M. P., Mangano R. M., Blume A. J., Beer B. and Hoebel B. G. (1991) Interleukin-1β decreases acetylcholine measured by microdialysis in the hippocampus of freely moving rats. Brain Res. 550, 287-290.
    • (1991) Brain Res. , vol.550 , pp. 287-290
    • Rada, P.1    Mark, G.P.2    Vitek, M.P.3    Mangano, R.M.4    Blume, A.J.5    Beer, B.6    Hoebel, B.G.7
  • 37
    • 0028278727 scopus 로고
    • In the rat, endogenous nitric oxide modulates the response of the hypothalamic-pituitary-adrenal axis to interleukin-1β, vasopressin, and oxytocin
    • Rivier C. and Shen G. H. (1994) In the rat, endogenous nitric oxide modulates the response of the hypothalamic-pituitary-adrenal axis to interleukin-1β, vasopressin, and oxytocin. J. Neurosci. 14, 1985-1993.
    • (1994) J. Neurosci. , vol.14 , pp. 1985-1993
    • Rivier, C.1    Shen, G.H.2
  • 38
    • 0026076534 scopus 로고
    • Functions and mechanisms of interleukin 1 in the brain
    • Rothwell N. J. (1991) Functions and mechanisms of interleukin 1 in the brain. Trends pharmac. Sci. 12, 430-436.
    • (1991) Trends Pharmac. Sci. , vol.12 , pp. 430-436
    • Rothwell, N.J.1
  • 39
    • 0028979741 scopus 로고
    • Anatomic patterns of fos immunostaining in rat brain following systemic endotoxin administration
    • Sagar S. M., Price K. J., Kasting N. W. and Sharp F. R. (1995) Anatomic patterns of fos immunostaining in rat brain following systemic endotoxin administration. Brain Res. Bull. 36, 381-392.
    • (1995) Brain Res. Bull. , vol.36 , pp. 381-392
    • Sagar, S.M.1    Price, K.J.2    Kasting, N.W.3    Sharp, F.R.4
  • 40
    • 0027970546 scopus 로고
    • Gene expression and function of interleukin 1, interleukin 6 and tumour necrosis factor in the brain
    • Schöbitz B., De Kloet E. R. and Holsboer F. (1994) Gene expression and function of interleukin 1, interleukin 6 and tumour necrosis factor in the brain. Prog. Neurobiol. 44, 397-432.
    • (1994) Prog. Neurobiol. , vol.44 , pp. 397-432
    • Schöbitz, B.1    De Kloet, E.R.2    Holsboer, F.3
  • 41
    • 0027176336 scopus 로고
    • Interleukin-1β augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus
    • Shintani F., Kanba S., Nakaki T., Nibuya M., Kinoshita N., Suzuki E., Yagi G., Kato R. and Asai M. (1993) Interleukin-1β augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus. J. Neurosci. 13, 3574-3581.
    • (1993) J. Neurosci. , vol.13 , pp. 3574-3581
    • Shintani, F.1    Kanba, S.2    Nakaki, T.3    Nibuya, M.4    Kinoshita, N.5    Suzuki, E.6    Yagi, G.7    Kato, R.8    Asai, M.9
  • 42
    • 0002561669 scopus 로고
    • The hypothalamus
    • (eds Björklund A., Hökfelt T. and Swanson L. W.), Elsevier Science, Amsterdam
    • Swanson L. W. (1987) The hypothalamus. In Handbook of Chemical Neuroanatomy. Vol. 5: Integrated Systems of the CNS (eds Björklund A., Hökfelt T. and Swanson L. W.), Part I, pp. 1-124. Elsevier Science, Amsterdam.
    • (1987) Handbook of Chemical Neuroanatomy. Vol. 5: Integrated Systems of the CNS , vol.5 , Issue.PART I , pp. 1-124
    • Swanson, L.W.1
  • 43
    • 0000066209 scopus 로고
    • The limbic region. I: The septohippocampal system
    • (eds Björklund A., Hökfelt T. and Swanson L. W.), Elsevier Science, Amsterdam
    • Swanson L. W., Köhler C. and Björklund A. (1987) The limbic region. I: The septohippocampal system. In Handbook of Chemical Neuroanatomy. Vol. 5: Integrated Systems of the CNS (eds Björklund A., Hökfelt T. and Swanson L. W.), Part I, pp. 125-277. Elsevier Science, Amsterdam.
    • (1987) Handbook of Chemical Neuroanatomy. Vol. 5: Integrated Systems of the CNS , vol.5 , Issue.PART I , pp. 125-277
    • Swanson, L.W.1    Köhler, C.2    Björklund, A.3
  • 44
    • 0027520773 scopus 로고
    • Reciprocal modulation of interleukin-1β (IL-1-β) and IL-1 receptors by lipopolysaccharide (endotoxin) treatment in the mouse brain-endocrine-immune axis
    • Takao T., Culp S. G. and De Souza E. B. (1993) Reciprocal modulation of interleukin-1β (IL-1-β) and IL-1 receptors by lipopolysaccharide (endotoxin) treatment in the mouse brain-endocrine-immune axis. Endocrinology 132, 1497-1504.
    • (1993) Endocrinology , vol.132 , pp. 1497-1504
    • Takao, T.1    Culp, S.G.2    De Souza, E.B.3
  • 45
    • 0028953739 scopus 로고
    • Endotoxin-induced appearance of immunoreactive interleukin-1β in ramified microglia in rat brain: A light and electron microscopic study
    • Van Dam A.-M., Bauer J., Tilders F. J. H. and Berkenbosch F. (1995) Endotoxin-induced appearance of immunoreactive interleukin-1β in ramified microglia in rat brain: a light and electron microscopic study. Neuroscience 65, 815-826.
    • (1995) Neuroscience , vol.65 , pp. 815-826
    • Van Dam, A.-M.1    Bauer, J.2    Tilders, F.J.H.3    Berkenbosch, F.4
  • 46
    • 0027260474 scopus 로고
    • Differential induction of c-Fos immunoreactivity in hypothalamus and brain stem nuclei following central and peripheral administration of endotoxin
    • Wan W., Janz L., Vriend C. Y., Sorensen C. M., Greenberg A. H. and Nance D. M. (1993) Differential induction of c-Fos immunoreactivity in hypothalamus and brain stem nuclei following central and peripheral administration of endotoxin. Brain Res. Bull. 32, 581-587.
    • (1993) Brain Res. Bull. , vol.32 , pp. 581-587
    • Wan, W.1    Janz, L.2    Vriend, C.Y.3    Sorensen, C.M.4    Greenberg, A.H.5    Nance, D.M.6
  • 47
    • 0025300455 scopus 로고
    • ACTH response induced by interleukin-1 is mediated by CRF secretion stimulated by hypothalamic PGE
    • Watanabe T., Morimoto A., Sakata Y. and Murakami N. (1990) ACTH response induced by interleukin-1 is mediated by CRF secretion stimulated by hypothalamic PGE. Experientia 46, 481-484.
    • (1990) Experientia , vol.46 , pp. 481-484
    • Watanabe, T.1    Morimoto, A.2    Sakata, Y.3    Murakami, N.4
  • 48
    • 0025790173 scopus 로고
    • Extracellular serotonin levels change with behavioral state but not with pyrogen-induced hyperthermia
    • Wilkinson L. O., Auerbach S. B. and Jacobs B. L. (1991) Extracellular serotonin levels change with behavioral state but not with pyrogen-induced hyperthermia. J. Neurosci. 11, 2732-2741.
    • (1991) J. Neurosci. , vol.11 , pp. 2732-2741
    • Wilkinson, L.O.1    Auerbach, S.B.2    Jacobs, B.L.3


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