Synergistic anticancer effects of combined γ-tocotrienol and oridonin treatment is associated with the induction of autophagy

Molecular and Cellular Biochemistry

Volumn 408, Issue 1-2, 2015, Pages 123-137

  Tiwari, Roshan V ^a   Parajuli, Parash ^a   Sylvester, Paul W ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

Author keywords

Autophagy; Beclin 1; Breast cancer; Cathepsin D; LAMP 1; Tocotrienol

Indexed keywords

3 METHYLADENINE; ANTINEOPLASTIC AGENT; AUTOPHAGY PROTEIN 12; AUTOPHAGY PROTEIN 3; AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; BAFILOMYCIN A1; BECLIN 1; CASPASE 3; CATHEPSIN D; GAMMA TOCOTRIENOL; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; ORIDONIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; BIOLOGICAL MARKER; CHROMAN DERIVATIVE; KAURANE DERIVATIVE; PLASTOCHROMANOL 8;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BREAST ADENOCARCINOMA; BREAST CANCER CELL LINE; BREAST EPITHELIUM CELL; CANCER INHIBITION; CELL GROWTH; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; DOSE RESPONSE; DRUG POTENTIATION; FEMALE; IC50; INTRACELLULAR SIGNALING; LOW DRUG DOSE; LYSOSOME; MITOGENESIS; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; ANALOGS AND DERIVATIVES; ANIMAL; BREAST NEOPLASMS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AUTOPHAGY; BIOMARKERS; BREAST NEOPLASMS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHROMANS; DITERPENES, KAURANE; DRUG SYNERGISM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; MICE; VITAMIN E;

EID: 84941994889     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2488-x     Document Type: Article

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