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Volumn 10, Issue 7, 2015, Pages

Remodeling of tight junctions and enhancement of barrier integrity of the CACO-2 intestinal epithelial cell layer by micronutrients

Author keywords

[No Author keywords available]

Indexed keywords

BERBERINE; BUTYRIC ACID; CLAUDIN 2; CLAUDIN 5; CLAUDIN 7; INDOLE; MANNITOL; QUERCETIN; TIGHT JUNCTION PROTEIN; TRACE ELEMENT; ZINC; BUTYRIC ACID DERIVATIVE; CLAUDIN;

EID: 84941985215     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0133926     Document Type: Article
Times cited : (102)

References (46)
  • 2
    • 84873088762 scopus 로고    scopus 로고
    • Tight junction-related human diseases
    • Sawada N (2013) Tight junction-related human diseases. Pathol Int 63: 1-12. doi: 10. 1111/pin. 12021
    • (2013) Pathol Int , vol.63 , pp. 1-12
    • Sawada, N.1
  • 3
    • 70449466824 scopus 로고    scopus 로고
    • The tight junction in inflammatory disease: Communication breakdown
    • Edelblum KL, Turner JR (2009) The tight junction in inflammatory disease: communication breakdown. Curr Opin Pharmacol 9: 715-720. doi: 10. 1016/j. coph. 2009. 06. 022
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 715-720
    • Edelblum, K.L.1    Turner, J.R.2
  • 5
    • 70449505391 scopus 로고    scopus 로고
    • Therapeutic options to modulate barrier defects in inflammatory bowel disease
    • Hering NA, Schulzke JD (2009) Therapeutic options to modulate barrier defects in inflammatory bowel disease. Dig Dis 27: 450-454. doi: 10. 1159/000233283
    • (2009) Dig Dis , vol.27 , pp. 450-454
    • Hering, N.A.1    Schulzke, J.D.2
  • 6
    • 79955518664 scopus 로고    scopus 로고
    • Regulation of tight junction permeability by intestinal bacteria and dietary components
    • Ulluwishewa D, Anderson RC, McNabb WC, Moughan PJ, Wells JM, Roy N. C. (2011) Regulation of tight junction permeability by intestinal bacteria and dietary components. J Nutr 141: 769-776. doi: 10. 3945/jn. 110. 135657
    • (2011) J Nutr , vol.141 , pp. 769-776
    • Ulluwishewa, D.1    Anderson, R.C.2    McNabb, W.C.3    Moughan, P.J.4    Wells, J.M.5    Roy, N.C.6
  • 7
    • 63249098521 scopus 로고    scopus 로고
    • Tight junctions as targets of infectious agents
    • Guttman JA, Finlay BB (2009) Tight junctions as targets of infectious agents. Biochim Biophys Acta 4: 832-841.
    • (2009) Biochim Biophys Acta , vol.4 , pp. 832-841
    • Guttman, J.A.1    Finlay, B.B.2
  • 8
    • 84893584653 scopus 로고    scopus 로고
    • Enhancement of tight junctional barrier function by micronutrients: Compound-specific effects on permeability and claudin composition
    • Mercado J, Valenzano MC, Jeffers C, Sedlak J, Cugliari MK, Papanikolaou E. , et al. (2013) Enhancement of tight junctional barrier function by micronutrients: compound-specific effects on permeability and claudin composition. PLoS ONE 8: 2013.
    • (2013) PLoS ONE 2013 , vol.8
    • Mercado, J.1    Valenzano, M.C.2    Jeffers, C.3    Sedlak, J.4    Cugliari, M.K.5    Papanikolaou, E.6
  • 9
    • 0030836745 scopus 로고    scopus 로고
    • Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea-A community-based, double-blind controlled trial
    • Sazawal S, Black RE, Bhan MK, Jalla S, Sinha A, Bhandari N. . (1997) Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea-A community-based, double-blind, controlled trial. Am J Clin Nutr 66: 413-418.
    • (1997) Am J Clin Nutr , vol.66 , pp. 413-418
    • Sazawal, S.1    Black, R.E.2    Bhan, M.K.3    Jalla, S.4    Sinha, A.5    Bhandari, N.6
  • 10
    • 51049095119 scopus 로고    scopus 로고
    • Zinc deficiency induces membrane barrier damage and increases neutrophil transmigration in Caco-2 cells
    • Finamore A, Massimi M, Conti Devirgiliis L, Mengheri E (2008) Zinc deficiency induces membrane barrier damage and increases neutrophil transmigration in Caco-2 cells. J Nutr 138: 1664-1670.
    • (2008) J Nutr , vol.138 , pp. 1664-1670
    • Finamore, A.1    Massimi, M.2    Conti Devirgiliis, L.3    Mengheri, E.4
  • 11
    • 84873143217 scopus 로고    scopus 로고
    • Zinc supplementation modifies tight junctions and alters barrier function of CACO-2 human intestinal epithelial layers
    • Wang X, Valenzano MC, Mercado JM, Zurbach EP, Mullin JM (2013) Zinc supplementation modifies tight junctions and alters barrier function of CACO-2 human intestinal epithelial layers. Dig Dis Sci 58: 77-87. doi: 10. 1007/s10620-012-2328-8
    • (2013) Dig Dis Sci , vol.58 , pp. 77-87
    • Wang, X.1    Valenzano, M.C.2    Mercado, J.M.3    Zurbach, E.P.4    Mullin, J.M.5
  • 12
    • 70350088307 scopus 로고    scopus 로고
    • Supplemental zinc reduced intestinal permeability by enhancing occludin and zonula occludens protein-1 (ZO-1 expression in weaning piglets
    • Zhang B, Guo Y (2009) Supplemental zinc reduced intestinal permeability by enhancing occludin and zonula occludens protein-1 (ZO-1) expression in weaning piglets. Br J Nutr 102: 687-693. doi: 10. 1017/S0007114509289033
    • (2009) Br J Nutr , vol.102 , pp. 687-693
    • Zhang, B.1    Guo, Y.2
  • 13
    • 0029797060 scopus 로고    scopus 로고
    • Intestinal paracellular permeability during malnutrition in Guinea pigs: Effect of high dietary zinc
    • Rodriguez P, Darmon N, Chappuis P, Candalh C, Blaton MA, Bouchaud C. , et al. . (1996) Intestinal paracellular permeability during malnutrition in guinea pigs: effect of high dietary zinc. Gut 39: 416-422.
    • (1996) Gut , vol.39 , pp. 416-422
    • Rodriguez, P.1    Darmon, N.2    Chappuis, P.3    Candalh, C.4    Blaton, M.A.5    Bouchaud, C.6
  • 14
  • 16
    • 69549114504 scopus 로고    scopus 로고
    • Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-Activated protein kinase in Caco-2 cell monolayers
    • Peng L, Li ZR, Green RS, Holzman IR, Lin J (2009) Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-Activated protein kinase in Caco-2 cell monolayers. J Nutr 139: 1619-1625. doi: 10. 3945/jn. 109. 104638
    • (2009) J Nutr , vol.139 , pp. 1619-1625
    • Peng, L.1    Li, Z.R.2    Green, R.S.3    Holzman, I.R.4    Lin, J.5
  • 17
    • 84871629387 scopus 로고    scopus 로고
    • Butyrate enhances intestinal epithelial barrier function via up-regulation of tight junction protein Claudin-1 transcription
    • Wang HB, Wang PY, Wang X, Wan YL, Liu YC (2012) Butyrate enhances intestinal epithelial barrier function via up-regulation of tight junction protein Claudin-1 transcription. Dig Dis Sci 57: 3126-3135. doi: 10. 1007/s10620-012-2259-4
    • (2012) Dig Dis Sci , vol.57 , pp. 3126-3135
    • Wang, H.B.1    Wang, P.Y.2    Wang, X.3    Wan, Y.L.4    Liu, Y.C.5
  • 19
    • 76249101130 scopus 로고    scopus 로고
    • The bacterial signal indole increases epithelialcell tight-junction resistance and attenuates indicators of inflammation
    • Bansal T, Alaniz RC, Wood TK, Jayaraman A (2009) The bacterial signal indole increases epithelialcell tight-junction resistance and attenuates indicators of inflammation. Proc Natl Acad Sci U S A 107: 228-233. doi: 10. 1073/pnas. 0906112107
    • (2009) Proc Natl Acad Sci U S A , vol.107 , pp. 228-233
    • Bansal, T.1    Alaniz, R.C.2    Wood, T.K.3    Jayaraman, A.4
  • 20
    • 80054111810 scopus 로고    scopus 로고
    • Fermentation in the human large intestine: Its physiologic consequences and the potential contribution of prebiotics
    • Macfarlane GT, Macfarlane S (2011) Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics. J Clin Gastroenterol 2011.
    • (2011) J Clin Gastroenterol. 2011
    • Macfarlane, G.T.1    Macfarlane, S.2
  • 21
    • 0018297290 scopus 로고
    • Microbial metabolites of tryptophan in the intestinal tract with special reference to skatole
    • Yokoyama MT, Carlson JR (1979) Microbial metabolites of tryptophan in the intestinal tract with special reference to skatole. Am J Clin Nutr 32: 173-178
    • (1979) Am J Clin Nutr , vol.32 , pp. 173-178
    • Yokoyama, M.T.1    Carlson, J.R.2
  • 22
    • 34547115000 scopus 로고    scopus 로고
    • The effect of nicotine in vitro on the integrity of tight junctions in Caco-2 cell monolayers
    • McGilligan VE, Wallace JM, Heavey PM, Ridley DL, Rowland IR (2007) The effect of nicotine in vitro on the integrity of tight junctions in Caco-2 cell monolayers. Food Chem Toxicol 45: 1593-1598.
    • (2007) Food Chem Toxicol , vol.45 , pp. 1593-1598
    • McGilligan, V.E.1    Wallace, J.M.2    Heavey, P.M.3    Ridley, D.L.4    Rowland, I.R.5
  • 23
    • 78649730159 scopus 로고    scopus 로고
    • TNFalpha-induced and berberine-Antagonized tight junction barrier impairment via tyrosine kinase Akt and NFkappaB signaling
    • Amasheh M, Fromm A, Krug SM, Amasheh S, Andres S, Zeitz M. , et al. (2010) TNFalpha-induced and berberine-Antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFkappaB signaling. J Cell Sci 123: 4145-4155. doi: 10. 1242/jcs. 070896
    • (2010) J Cell Sci , vol.123 , pp. 4145-4155
    • Amasheh, M.1    Fromm, A.2    Krug, S.M.3    Amasheh, S.4    Andres, S.5    Zeitz, M.6
  • 24
    • 67349272274 scopus 로고    scopus 로고
    • The effect of berberine in vitro on tight junctions in human Caco-2 intestinal epithelial cells
    • Gu L, Li N, Li Q, Zhang Q, Wang C, Zhu W. , et al. (2009) The effect of berberine in vitro on tight junctions in human Caco-2 intestinal epithelial cells. Fitoterapia 80: 241-248. doi: 10. 1016/j. fitote. 2009. 02. 005
    • (2009) Fitoterapia , vol.80 , pp. 241-248
    • Gu, L.1    Li, N.2    Li, Q.3    Zhang, Q.4    Wang, C.5    Zhu, W.6
  • 25
    • 65349095529 scopus 로고    scopus 로고
    • Quercetin enhances intestinal barrier function through the assembly of zonula [corrected] occludens-2, occludin, and claudin-1 and the expression of claudin-4 in Caco-2 cells
    • Suzuki T, Hara H (2009) Quercetin enhances intestinal barrier function through the assembly of zonula [corrected] occludens-2, occludin, and claudin-1 and the expression of claudin-4 in Caco-2 cells. J Nutr 139: 965-974. doi: 10. 3945/jn. 108. 100867
    • (2009) J Nutr , vol.139 , pp. 965-974
    • Suzuki, T.1    Hara, H.2
  • 26
    • 44449100218 scopus 로고    scopus 로고
    • Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells
    • Amasheh M, Schlichter S, Amasheh S, Mankertz J, Zeitz M, Fromm M. ,et al. (2008) Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells. J Nutr 138: 1067-1073.
    • (2008) J Nutr , vol.138 , pp. 1067-1073
    • Amasheh, M.1    Schlichter, S.2    Amasheh, S.3    Mankertz, J.4    Zeitz, M.5    Fromm, M.6
  • 27
    • 77956284923 scopus 로고    scopus 로고
    • Protective effect of quercetin on hydrogen peroxide-induced tight junction disruption
    • Chuenkitiyanon S, Pengsuparp T, Jianmongkol S (2010) Protective effect of quercetin on hydrogen peroxide-induced tight junction disruption. Int J Toxicol 29: 418-424. doi: 10. 1177/1091581810366487
    • (2010) Int J Toxicol , vol.29 , pp. 418-424
    • Chuenkitiyanon, S.1    Pengsuparp, T.2    Jianmongkol, S.3
  • 28
    • 0021490671 scopus 로고
    • Epithelial properties of human colonic carcinoma cell line Caco-2 electrical parameters
    • Grasset E, Pinto M, Dussaulx E, Zweibaum A, Desjeux JF (1984) Epithelial properties of human colonic carcinoma cell line Caco-2: electrical parameters. Am J Physiol 247: C260-267.
    • (1984) Am J Physiol , vol.247 , pp. C260-267
    • Grasset, E.1    Pinto, M.2    Dussaulx, E.3    Zweibaum, A.4    Desjeux, J.F.5
  • 29
    • 0026755585 scopus 로고
    • Characterization of the enterocyte-like brush border cytoskeleton of the C2BBe clones of the human intestinal cell line Caco-2
    • Peterson MD, Mooseker MS (1992) Characterization of the enterocyte-like brush border cytoskeleton of the C2BBe clones of the human intestinal cell line, Caco-2. J Cell Sci 102: 581-600.
    • (1992) J Cell Sci , vol.102 , pp. 581-600
    • Peterson, M.D.1    Mooseker, M.S.2
  • 30
    • 0024593744 scopus 로고
    • Characterization of the human colon carcinoma cell line (Caco-2 as a model system for intestinal epithelial permeability
    • Hidalgo IJ, Raub TJ, Borchardt RT (1989) Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96: 736-749.
    • (1989) Gastroenterology , vol.96 , pp. 736-749
    • Hidalgo, I.J.1    Raub, T.J.2    Borchardt, R.T.3
  • 31
    • 0034011377 scopus 로고    scopus 로고
    • Divergent phenotypic patterns and commitment to apoptosis of Caco-2 cells during spontaneous and butyrate-induced differentiation
    • Mariadason JM, Rickard KL, Barkla DH, Augenlicht LH, Gibson PR (2000) Divergent phenotypic patterns and commitment to apoptosis of Caco-2 cells during spontaneous and butyrate-induced differentiation. J Cell Physiol 183: 347-354.
    • (2000) J Cell Physiol , vol.183 , pp. 347-354
    • Mariadason, J.M.1    Rickard, K.L.2    Barkla, D.H.3    Augenlicht, L.H.4    Gibson, P.R.5
  • 32
    • 84882715057 scopus 로고    scopus 로고
    • Butyrate promotes the recovering of intestinal wound healing through its positive effect on the tight junctions
    • Ma X, Fan PX, Li LS, Qiao SY, Zhang GL, Li D. F. (2012) Butyrate promotes the recovering of intestinal wound healing through its positive effect on the tight junctions. J Anim Sci 4: 266-268.
    • (2012) J Anim Sci , vol.4 , pp. 266-268
    • Ma, X.1    Fan, P.X.2    Li, L.S.3    Qiao, S.Y.4    Zhang, G.L.5    Li, D.F.6
  • 33
    • 0036533679 scopus 로고    scopus 로고
    • Proteome analysis of butyratetreated human colon cancer cells (HT-29
    • Tan S, Seow TK, Liang RC, Koh S, Lee CP, Chung M. C. , et al. (2002) Proteome analysis of butyratetreated human colon cancer cells (HT-29). Int J Cancer 98: 523-531.
    • (2002) Int J Cancer , vol.98 , pp. 523-531
    • Tan, S.1    Seow, T.K.2    Liang, R.C.3    Koh, S.4    Lee, C.P.5    Chung, M.C.6
  • 34
    • 0035977063 scopus 로고    scopus 로고
    • Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity
    • Yin L, Laevsky G, Giardina C (2001) Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. J Biol Chem 276: 44641-44646.
    • (2001) J Biol Chem , vol.276 , pp. 44641-44646
    • Yin, L.1    Laevsky, G.2    Giardina, C.3
  • 35
    • 20444493613 scopus 로고    scopus 로고
    • Short-chain fatty acids alter tight junction permeability in intestinal monolayer cells via lipoxygenase activation
    • Ohata A, Usami M, Miyoshi M (2005) Short-chain fatty acids alter tight junction permeability in intestinal monolayer cells via lipoxygenase activation. Nutrition 21: 838-847.
    • (2005) Nutrition , vol.21 , pp. 838-847
    • Ohata, A.1    Usami, M.2    Miyoshi, M.3
  • 37
    • 84888398825 scopus 로고    scopus 로고
    • Short-chain fatty acids activate AMP-Activated protein kinase and ameliorate ethanol-induced intestinal barrier dysfunction in Caco-2 cell monolayers
    • Elamin EE, Masclee AA, Dekker J, Pieters HJ, Jonkers DM (2013) Short-chain fatty acids activate AMP-Activated protein kinase and ameliorate ethanol-induced intestinal barrier dysfunction in Caco-2 cell monolayers. J Nutr 143: 1872-1881. doi: 10. 3945/jn. 113. 179549
    • (2013) J Nutr , vol.143 , pp. 1872-1881
    • Elamin, E.E.1    Masclee, A.A.2    Dekker, J.3    Pieters, H.J.4    Jonkers, D.M.5
  • 38
    • 49649105797 scopus 로고    scopus 로고
    • Butyrate protects Caco-2 cells from Campylobacter jejuni invasion and translocation
    • Van Deun K, Pasmans F, Van Immerseel F, Ducatelle R, Haesebrouck F (2008) Butyrate protects Caco-2 cells from Campylobacter jejuni invasion and translocation. Br J Nutr 100: 480-484. doi: 10. 1017/S0007114508921693
    • (2008) Br J Nutr , vol.100 , pp. 480-484
    • Van Deun, K.1    Pasmans, F.2    Van Immerseel, F.3    Ducatelle, R.4    Haesebrouck, F.5
  • 39
    • 84894263389 scopus 로고    scopus 로고
    • Commensal bacteria-dependent indole production enhances epithelial barrier function in the colon
    • Shimada Y, Kinoshita M, Harada K, Mizutani M, Masahata K, Kayama H. , et al. (2013) Commensal bacteria-dependent indole production enhances epithelial barrier function in the colon. PLoS ONE 8: 2013.
    • (2013) PLoS ONE 2013 , vol.8
    • Shimada, Y.1    Kinoshita, M.2    Harada, K.3    Mizutani, M.4    Masahata, K.5    Kayama, H.6
  • 41
    • 84878664357 scopus 로고    scopus 로고
    • Polyphenols protect the epithelial barrier function of Caco-2 cells exposed to indomethacin through the modulation of occludin and zonula occludens-1 expression
    • Carrasco-Pozo C, Morales P, Gotteland M (2013) Polyphenols protect the epithelial barrier function of Caco-2 cells exposed to indomethacin through the modulation of occludin and zonula occludens-1 expression. J Agric Food Chem 61: 5291-5297. doi: 10. 1021/jf400150p
    • (2013) J Agric Food Chem , vol.61 , pp. 5291-5297
    • Carrasco-Pozo, C.1    Morales, P.2    Gotteland, M.3
  • 42
    • 84877077406 scopus 로고    scopus 로고
    • Amelioration of IFN-gamma and TNF-Alpha-induced intestinal epithelial barrier dysfunction by berberine via suppression of MLCK-MLC phosphorylation signaling pathway
    • Cao M, Wang P, Sun C, He W, Wang F (2013) Amelioration of IFN-gamma and TNF-Alpha-induced intestinal epithelial barrier dysfunction by berberine via suppression of MLCK-MLC phosphorylation signaling pathway. PLoS ONE 8: 2013.
    • (2013) PLoS ONE 2013 , vol.8
    • Cao, M.1    Wang, P.2    Sun, C.3    He, W.4    Wang, F.5
  • 43
    • 77951208947 scopus 로고    scopus 로고
    • Berberine attenuates pro-inflammatory cytokineinduced tight junction disruption in an in vitro model of intestinal epithelial cells
    • Li N, Gu L, Qu L, Gong J, Li Q, Zhu W. , et al. (2010) Berberine attenuates pro-inflammatory cytokineinduced tight junction disruption in an in vitro model of intestinal epithelial cells. Eur J Pharm Sci 40: 1-8. doi: 10. 1016/j. ejps. 2010. 02. 001
    • (2010) Eur J Pharm Sci , vol.40 , pp. 1-8
    • Li, N.1    Gu, L.2    Qu, L.3    Gong, J.4    Li, Q.5    Zhu, W.6
  • 44
    • 84859605336 scopus 로고    scopus 로고
    • Mechanisms of action of zinc on rat intestinal epithelial electrogenic ion secretion: Insights into its antidiarrhoeal actions
    • Bzik VA, Medani M, Baird AW, Winter DC, Brayden DJ (2012) Mechanisms of action of zinc on rat intestinal epithelial electrogenic ion secretion: insights into its antidiarrhoeal actions. J Pharm Pharmacol 64: 644-653. doi: 10. 1111/j. 2042-7158. 2011. 01441. x
    • (2012) J Pharm Pharmacol , vol.64 , pp. 644-653
    • Bzik, V.A.1    Medani, M.2    Baird, A.W.3    Winter, D.C.4    Brayden, D.J.5
  • 45
    • 78649975651 scopus 로고    scopus 로고
    • Epithelial barrier resistance is increased by the divalent cation zinc in cultured MDCKII epithelial monolayers
    • Carr G, Wright JA, Simmons NL (2010) Epithelial barrier resistance is increased by the divalent cation zinc in cultured MDCKII epithelial monolayers. J Membr Biol 237: 115-123. doi: 10. 1007/s00232-010-9312-z
    • (2010) J Membr Biol , vol.237 , pp. 115-123
    • Carr, G.1    Wright, J.A.2    Simmons, N.L.3
  • 46
    • 0033571047 scopus 로고    scopus 로고
    • Manner of interaction of heterogeneous claudin species within and between tight junction strands
    • Furuse M, Sasaki H, Tsukita S (1999) Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol 147: 891-903.
    • (1999) J Cell Biol , vol.147 , pp. 891-903
    • Furuse, M.1    Sasaki, H.2    Tsukita, S.3


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