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Volumn 58, Issue 1, 2013, Pages 77-87

Zinc supplementation modifies tight junctions and alters barrier function of CACO-2 human intestinal epithelial layers

Author keywords

CACO 2; Claudin; Claudins; Differentiation; Metallothionein; Nutrition; Paracellular; Tight junction; Zinc

Indexed keywords

CLAUDIN 2; CLAUDIN 7; OCCLUDIN; TRICELLULIN; ZINC;

EID: 84873143217     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2328-8     Document Type: Article
Times cited : (85)

References (41)
  • 1
    • 46149097697 scopus 로고    scopus 로고
    • Zinc
    • Bowman BA, Russell RM, eds. Washington, D.C.: ILSI Press
    • Cousins RJ, Zinc. In: Bowman BA, Russell RM, eds. Present Knowledge in Nutrition, vol 1. Washington, D.C.: ILSI Press; 2006:445-457.
    • (2006) Present Knowledge in Nutrition , vol.1 , pp. 445-457
    • Cousins, R.J.1
  • 3
    • 77951536164 scopus 로고    scopus 로고
    • Impact of the discovery of human zinc deficiency on health
    • 20150599 1:CAS:528:DC%2BC3cXhtVWmt70%3D
    • Prasad AS. Impact of the discovery of human zinc deficiency on health. J Am Coll Nutr. 2009;28:257-265.
    • (2009) J Am Coll Nutr , vol.28 , pp. 257-265
    • Prasad, A.S.1
  • 4
    • 0038670770 scopus 로고    scopus 로고
    • Zinc-altered immune function
    • 12730441 1:CAS:528:DC%2BD3sXjs1Oqsr8%3D
    • Ibs KH, Rink L. Zinc-altered immune function. J Nutr. 2003;133:1452S-1456S.
    • (2003) J Nutr , vol.133
    • Ibs, K.H.1    Rink, L.2
  • 5
    • 7944222171 scopus 로고    scopus 로고
    • Zinc deficiency, DNA damage and cancer risk
    • 15542347 10.1016/j.jnutbio.2004.07.005 1:CAS:528:DC%2BD2cXpslGls7k%3D
    • Ho E. Zinc deficiency, DNA damage and cancer risk. J Nutr Biochem. 2004;15:572-578.
    • (2004) J Nutr Biochem , vol.15 , pp. 572-578
    • Ho, E.1
  • 6
    • 67249142645 scopus 로고    scopus 로고
    • Modification of tight junction structure and permeability by nutritional means
    • 19538294 10.1111/j.1749-6632.2009.04028.x 1:CAS:528:DC%2BD1MXot1Ghurg%3D
    • Mullin JM, Skrovanek SM, Valenzano MC. Modification of tight junction structure and permeability by nutritional means. Ann NY Acad Sci. 2009;1165:99-112.
    • (2009) Ann NY Acad Sci , vol.1165 , pp. 99-112
    • Mullin, J.M.1    Skrovanek, S.M.2    Valenzano, M.C.3
  • 7
    • 69849111327 scopus 로고    scopus 로고
    • Inflamed pouch mucosa possesses altered tight junctions indicating recurrence of inflammatory bowel disease
    • 19488769 10.1007/s00384-009-0737-8
    • Amasheh S, Dullat S, Fromm M, Schulzke JD, Buhr HJ, Kroesen AJ. Inflamed pouch mucosa possesses altered tight junctions indicating recurrence of inflammatory bowel disease. Int J Colorectal Dis. 2009;24:1149-1156.
    • (2009) Int J Colorectal Dis , vol.24 , pp. 1149-1156
    • Amasheh, S.1    Dullat, S.2    Fromm, M.3    Schulzke, J.D.4    Buhr, H.J.5    Kroesen, A.J.6
  • 8
    • 0019996563 scopus 로고
    • Intestinal permeability in children with Crohn's disease and coeliac disease
    • 10.1136/bmj.285.6334.20 1:STN:280:DyaL383gslKmsw%3D%3D
    • Pearson AD, Eastham EJ, Laker MF, Craft AW, Nelson R. Intestinal permeability in children with Crohn's disease and coeliac disease. Br Med J (Clin Res Ed). 1982;285:20-21.
    • (1982) Br Med J (Clin Res Ed) , vol.285 , pp. 20-21
    • Pearson, A.D.1    Eastham, E.J.2    Laker, M.F.3    Craft, A.W.4    Nelson, R.5
  • 9
    • 0034782709 scopus 로고    scopus 로고
    • Zinc supplementation tightens "leaky gut" in Crohn's disease
    • 11383597 10.1097/00054725-200105000-00003 1:STN:280: DC%2BD3MzhtVKktA%3D%3D
    • Sturniolo GC, Di Leo V, Ferronato A, D'Odorico A, D'Inca R. Zinc supplementation tightens "Leaky gut" in Crohn's disease. Inflamm Bowel Dis. 2001;7:94-98.
    • (2001) Inflamm Bowel Dis , vol.7 , pp. 94-98
    • Sturniolo, G.C.1    Di Leo, V.2    Ferronato, A.3    D'Odorico, A.4    D'Inca, R.5
  • 10
    • 33845415089 scopus 로고    scopus 로고
    • Zinc modulates cytokine-induced lung epithelial cell barrier permeability
    • 16844947 10.1152/ajplung.00207.2006 1:CAS:528:DC%2BD2sXjvFCk
    • Bao S, Knoell DL. Zinc modulates cytokine-induced lung epithelial cell barrier permeability. Am J Physiol Lung Cell Mol Physiol. 2006;291:L1132-L1141.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291
    • Bao, S.1    Knoell, D.L.2
  • 11
    • 0029797060 scopus 로고    scopus 로고
    • Intestinal paracellular permeability during malnutrition in guinea pigs: Effect of high dietary zinc
    • 8949647 10.1136/gut.39.3.416 1:CAS:528:DyaK28XntFekurc%3D
    • Rodriguez P, Darmon N, Chappuis P, et al. Intestinal paracellular permeability during malnutrition in guinea pigs: effect of high dietary zinc. Gut. 1996;39:416-422.
    • (1996) Gut , vol.39 , pp. 416-422
    • Rodriguez, P.1    Darmon, N.2    Chappuis, P.3    Candalh, C.4    Blaton, M.A.5    Bouchaud, C.6    Heyman, M.7
  • 12
    • 79957850694 scopus 로고    scopus 로고
    • Oral zinc for treating diarrhoea in children
    • Lazzerini M, Ronfani L. Oral zinc for treating diarrhoea in children. Sao Paulo Med J 2011;129:118-119.
    • (2011) Sao Paulo Med J , vol.129 , pp. 118-119
    • Lazzerini, M.1    Ronfani, L.2
  • 14
    • 0026755585 scopus 로고
    • Characterization of the enterocyte-like brush border cytoskeleton of the c2bbe clones of the human intestinal cell line, CACO-2
    • 1506435 1:CAS:528:DyaK38Xls1ymsb8%3D
    • Peterson MD, Mooseker MS. Characterization of the enterocyte-like brush border cytoskeleton of the c2bbe clones of the human intestinal cell line, CACO-2. J Cell Sci. 1992;102:581-600.
    • (1992) J Cell Sci , vol.102 , pp. 581-600
    • Peterson, M.D.1    Mooseker, M.S.2
  • 15
    • 38449084547 scopus 로고    scopus 로고
    • Determination of drug permeability and prediction of drug absorption in caco-2 monolayers
    • 17853866 10.1038/nprot.2007.303 1:CAS:528:DC%2BD2sXhtFagsb%2FN
    • Hubatsch I, Ragnarsson EG, Artursson P. Determination of drug permeability and prediction of drug absorption in caco-2 monolayers. Nat Protoc. 2007;2:2111-2119.
    • (2007) Nat Protoc , vol.2 , pp. 2111-2119
    • Hubatsch, I.1    Ragnarsson, E.G.2    Artursson, P.3
  • 16
    • 80053610604 scopus 로고    scopus 로고
    • Differentiation- and polarization-dependent zinc tolerance in CACO-2 cells
    • 21103883 10.1007/s00394-010-0146-3
    • Zemann N, Zemann A, Klein P, Elmadfa I, Huettinger M. Differentiation- and polarization-dependent zinc tolerance in CACO-2 cells. Eur J Nutr. 2010;50:379-386.
    • (2010) Eur J Nutr , vol.50 , pp. 379-386
    • Zemann, N.1    Zemann, A.2    Klein, P.3    Elmadfa, I.4    Huettinger, M.5
  • 17
    • 34548455766 scopus 로고    scopus 로고
    • Restriction of sulfur-containing amino acids alters claudin composition and improves tight junction barrier function
    • 17567720 10.1152/ajpregu.00072.2007 1:CAS:528:DC%2BD2sXhtVOqtrfF
    • Skrovanek S, Valenzano MC, Mullin JM. Restriction of sulfur-containing amino acids alters claudin composition and improves tight junction barrier function. Am J Physiol Regul Integr Comp Physiol. 2007;293:R1046-R1055.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293
    • Skrovanek, S.1    Valenzano, M.C.2    Mullin, J.M.3
  • 18
    • 0030994411 scopus 로고    scopus 로고
    • Different size limitations for increased transepithelial paracellular solute flux across phorbol ester and tumor necrosis factor-treated epithelial cell sheets
    • 9130471 10.1002/(SICI)1097-4652(199705)171:2<226: AID-JCP14>3.0. CO;2-B 1:CAS:528:DyaK2sXivVKjsb8%3D
    • Mullin JM, Marano CW, Laughlin KV, Nuciglio M, Stevenson BR, Soler P. Different size limitations for increased transepithelial paracellular solute flux across phorbol ester and tumor necrosis factor-treated epithelial cell sheets. J Cell Physiol. 1997;171:226-233.
    • (1997) J Cell Physiol , vol.171 , pp. 226-233
    • Mullin, J.M.1    Marano, C.W.2    Laughlin, K.V.3    Nuciglio, M.4    Stevenson, B.R.5    Soler, P.6
  • 19
    • 6544229829 scopus 로고
    • A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid
    • 13293190 1:CAS:528:DyaG28XktVyktQ%3D%3D
    • Burton K. A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J. 1956;62:315-323.
    • (1956) Biochem J , vol.62 , pp. 315-323
    • Burton, K.1
  • 20
    • 0022518347 scopus 로고
    • Basal-lateral transport and transcellular flux of methyl alpha-d-glucoside across LLC-PK1 renal epithelial cells
    • 3081050 10.1016/0167-4889(86)90237-5 1:CAS:528:DyaL28XhsVKjtL4%3D
    • Mullin JM, Fluk L, Kleinzeller A. Basal-lateral transport and transcellular flux of methyl alpha-d-glucoside across LLC-PK1 renal epithelial cells. Biochim Biophys Acta. 1986;885:233-239.
    • (1986) Biochim Biophys Acta , vol.885 , pp. 233-239
    • Mullin, J.M.1    Fluk, L.2    Kleinzeller, A.3
  • 21
    • 0022966713 scopus 로고
    • Reassembly of the occluding junctions in a renal cell line with characteristics of proximal tubular cells
    • 3789160 1:STN:280:DyaL2s%2FntlOktw%3D%3D
    • Rabito CA. Reassembly of the occluding junctions in a renal cell line with characteristics of proximal tubular cells. Am J Physiol. 1986;251:F978-F987.
    • (1986) Am J Physiol , vol.251
    • Rabito, C.A.1
  • 22
    • 51049095119 scopus 로고    scopus 로고
    • Zinc deficiency induces membrane barrier damage and increases neutrophil transmigration in CACO-2 cells
    • 18716167 1:CAS:528:DC%2BD1cXhtVylurvM
    • Finamore A, Massimi M, Conti Devirgiliis L, Mengheri E. Zinc deficiency induces membrane barrier damage and increases neutrophil transmigration in CACO-2 cells. J Nutr. 2008;138:1664-1670.
    • (2008) J Nutr , vol.138 , pp. 1664-1670
    • Finamore, A.1    Massimi, M.2    Conti Devirgiliis, L.3    Mengheri, E.4
  • 25
    • 70350088307 scopus 로고    scopus 로고
    • Supplemental zinc reduced intestinal permeability by enhancing occludin and zonula occludens protein-1 (ZO-1) expression in weaning piglets
    • 19267955 10.1017/S0007114509289033 1:CAS:528:DC%2BD1MXht1Squ7rL
    • Zhang B, Guo Y. Supplemental zinc reduced intestinal permeability by enhancing occludin and zonula occludens protein-1 (ZO-1) expression in weaning piglets. Br J Nutr. 2009;102:687-693.
    • (2009) Br J Nutr , vol.102 , pp. 687-693
    • Zhang, B.1    Guo, Y.2
  • 26
    • 0036014842 scopus 로고    scopus 로고
    • Effect of zinc supplementation on intestinal permeability in experimental colitis
    • 12032492 10.1067/mlc.2002.123624 1:CAS:528:DC%2BD38XltVSqs78%3D
    • Sturniolo GC, Fries W, Mazzon E, Di Leo V, Barollo M, D'Inca R. Effect of zinc supplementation on intestinal permeability in experimental colitis. J Lab Clin Med. 2002;139:311-315.
    • (2002) J Lab Clin Med , vol.139 , pp. 311-315
    • Sturniolo, G.C.1    Fries, W.2    Mazzon, E.3    Di Leo, V.4    Barollo, M.5    D'Inca, R.6
  • 27
    • 70350702664 scopus 로고    scopus 로고
    • Intracellular zinc stores protect the intestinal epithelium from ochratoxin a toxicity
    • 19720134 10.1016/j.tiv.2009.08.012 1:CAS:528:DC%2BD1MXhsVajtb7O
    • Ranaldi G, Caprini V, Sambuy Y, Perozzi G, Murgia C. Intracellular zinc stores protect the intestinal epithelium from ochratoxin a toxicity. Toxicol in Vitro. 2009;23:1516-1521.
    • (2009) Toxicol in Vitro , vol.23 , pp. 1516-1521
    • Ranaldi, G.1    Caprini, V.2    Sambuy, Y.3    Perozzi, G.4    Murgia, C.5
  • 28
    • 0344306527 scopus 로고    scopus 로고
    • Zinc oxide protects cultured enterocytes from the damage induced by escherichia coli
    • 14652351 1:CAS:528:DC%2BD3sXpslGmtLs%3D
    • Roselli M, Finamore A, Garaguso I, Britti MS, Mengheri E. Zinc oxide protects cultured enterocytes from the damage induced by escherichia coli. J Nutr. 2003;133:4077-4082.
    • (2003) J Nutr , vol.133 , pp. 4077-4082
    • Roselli, M.1    Finamore, A.2    Garaguso, I.3    Britti, M.S.4    Mengheri, E.5
  • 29
    • 84856592136 scopus 로고    scopus 로고
    • Editorial augmenting epithelial barrier function
    • 10.2174/1875044301205010010
    • Mullin JM. Editorial: Augmenting epithelial barrier function. J Epithelial Biol Pharmacol. 2012;5:10-12.
    • (2012) J Epithelial Biol Pharmacol , vol.5 , pp. 10-12
    • Mullin, J.M.1
  • 30
    • 44149116211 scopus 로고    scopus 로고
    • Cooperation of metallothionein and zinc transporters for regulating zinc homeostasis in human intestinal caco-2 cells
    • 19083439 10.1016/j.nutres.2008.02.011 1:CAS:528:DC%2BD1cXms1Wktr0%3D
    • Shen H, Qin H, Guo J. Cooperation of metallothionein and zinc transporters for regulating zinc homeostasis in human intestinal caco-2 cells. Nutr Res. 2008;28:406-413.
    • (2008) Nutr Res , vol.28 , pp. 406-413
    • Shen, H.1    Qin, H.2    Guo, J.3
  • 31
    • 77953139645 scopus 로고    scopus 로고
    • Effects of zinc exposure on zinc transporter expression in human intestinal cells of varying maturity
    • 20479680 10.1097/MPG.0b013e3181d98e85 1:CAS:528:DC%2BC3cXmsFCjsrg%3D
    • Jou MY, Philipps AF, Kelleher SL, Lonnerdal B. Effects of zinc exposure on zinc transporter expression in human intestinal cells of varying maturity. J Pediatr Gastroenterol Nutr. 2010;50:587-595.
    • (2010) J Pediatr Gastroenterol Nutr , vol.50 , pp. 587-595
    • Jou, M.Y.1    Philipps, A.F.2    Kelleher, S.L.3    Lonnerdal, B.4
  • 32
    • 70350002060 scopus 로고    scopus 로고
    • The claudins
    • 19706201 10.1186/gb-2009-10-8-235
    • Lal-Nag M, Morin PJ. The claudins. Genome Biol. 2009;10:235.
    • (2009) Genome Biol , vol.10 , pp. 235
    • Lal-Nag, M.1    Morin, P.J.2
  • 33
    • 14744270867 scopus 로고    scopus 로고
    • Differential expression of claudin-2 along the human intestine: Implication of gata-4 in the maintenance of claudin-2 in differentiating cells
    • 15389642 10.1002/jcp.20189 1:CAS:528:DC%2BD2MXit1SqtLo%3D
    • Escaffit F, Boudreau F, Beaulieu JF. Differential expression of claudin-2 along the human intestine: implication of gata-4 in the maintenance of claudin-2 in differentiating cells. J Cell Physiol. 2005;203:15-26.
    • (2005) J Cell Physiol , vol.203 , pp. 15-26
    • Escaffit, F.1    Boudreau, F.2    Beaulieu, J.F.3
  • 35
    • 33645963995 scopus 로고    scopus 로고
    • Claudins and epithelial paracellular transport
    • 16460278 10.1146/annurev.physiol.68.040104.131404
    • Van Itallie CM, Anderson JM. Claudins and epithelial paracellular transport. Annu Rev Physiol. 2006;68:403-429.
    • (2006) Annu Rev Physiol , vol.68 , pp. 403-429
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 36
    • 21644461890 scopus 로고    scopus 로고
    • + conductance in LLC-PK1 cells
    • 15928046 10.1242/jcs.02406 1:CAS:528:DC%2BD2MXmtF2ntb8%3D
    • + conductance in LLC-PK1 cells. J Cell Sci. 2005;118:2683-2693.
    • (2005) J Cell Sci , vol.118 , pp. 2683-2693
    • Alexandre, M.D.1    Lu, Q.2    Chen, Y.H.3
  • 37
    • 0025061063 scopus 로고
    • Effects of phlorizin and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia
    • 2105653 1:CAS:528:DyaK3cXhtFKnsLY%3D
    • Atisook K, Carlson S, Madara JL. Effects of phlorizin and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia. Am J Physiol. 1990;258:C77-C85.
    • (1990) Am J Physiol , vol.258
    • Atisook, K.1    Carlson, S.2    Madara, J.L.3
  • 38
    • 0029167043 scopus 로고
    • Regulation of tight-junction permeability during nutrient absorption across the intestinal epithelium
    • 8527224 10.1146/annurev.nu.15.070195.000343 1:CAS:528:DyaK2MXntVCjsr4%3D
    • Ballard ST, Hunter JH, Taylor AE. Regulation of tight-junction permeability during nutrient absorption across the intestinal epithelium. Annu Rev Nutr. 1995;15:35-55.
    • (1995) Annu Rev Nutr , vol.15 , pp. 35-55
    • Ballard, S.T.1    Hunter, J.H.2    Taylor, A.E.3
  • 39
    • 0025637226 scopus 로고
    • Use of the paracellular way for the intestinal absorption of sugars
    • 2129176 1:CAS:528:DyaK3MXmsFalsb4%3D
    • Gato-Pecina JJ, Ponz F. Use of the paracellular way for the intestinal absorption of sugars. Rev Esp Fisiol. 1990;46:343-352.
    • (1990) Rev Esp Fisiol , vol.46 , pp. 343-352
    • Gato-Pecina, J.J.1    Ponz, F.2
  • 40
    • 0027763397 scopus 로고
    • Luminal nutrients alter tight-junction permeability in the rat jejunum: An in vivo perfusion model
    • 7511482 10.1139/y93-125 1:CAS:528:DyaK2cXhtVaqt7Y%3D
    • Sadowski DC, Meddings JB. Luminal nutrients alter tight-junction permeability in the rat jejunum: an in vivo perfusion model. Can J Physiol Pharmacol. 1993;71:835-839.
    • (1993) Can J Physiol Pharmacol , vol.71 , pp. 835-839
    • Sadowski, D.C.1    Meddings, J.B.2
  • 41
    • 78649975651 scopus 로고    scopus 로고
    • Epithelial barrier resistance is increased by the divalent cation zinc in cultured MDCKII epithelial monolayers
    • Carr G, Wright JA, Simmons NL. Epithelial barrier resistance is increased by the divalent cation zinc in cultured MDCKII epithelial monolayers. J Membr Biol 2010;237:115-123.
    • (2010) J Membr Biol , vol.237 , pp. 115-123
    • Carr, G.1    Wright, J.A.2    Simmons, N.L.3


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