PEITC inhibits human brain glioblastoma GBM 8401 cell migration and invasion through the inhibition of uPA, Rho A, and Ras with inhibition of MMP-2, -7 and -9 gene expression

Oncology Reports

Volumn 34, Issue 5, 2015, Pages 2489-2496

  Chou, Yu Cheng ^a,b,c,d   Chang, Meng Ya ^b   Wang, Mei Jen ^b,g   Yu, Fu Shun ^e   Liu, Hsin Chung ^e   Harnod, Tomor ^b   Hung, Chih Huang ^b   Lee, Hsu Tung ^a,c   Chung, Jing Gung ^e,f  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

^f ASIA UNIVERSITY   (Taiwan)

^g BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

Glioblastoma; Invasion; Matrix metalloproteinases; Migration; PEITC

Indexed keywords

COLLAGENASE 3; GELATINASE A; GELATINASE B; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MATRILYSIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHENETHYL ISOTHIOCYANATE; RAS PROTEIN; RHO KINASE; SOS PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; TEMOZOLOMIDE; UROKINASE; ANTINEOPLASTIC AGENT; ISOTHIOCYANIC ACID DERIVATIVE; MMP2 PROTEIN, HUMAN; MMP7 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL INVASION; CELL MIGRATION; CELL MIGRATION ASSAY; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG DETERMINATION; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; ENZYME REPRESSION; GBM 8401 CELL LINE; GENE EXPRESSION REGULATION; GENE REPRESSION; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; MIGRATION INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; BRAIN NEOPLASMS; CELL MOTION; CELL SURVIVAL; DRUG EFFECTS; DRUG SCREENING; ENZYMOLOGY; GENE EXPRESSION; GENETICS; GLIOBLASTOMA; METABOLISM; PATHOLOGY; TUMOR CELL LINE; TUMOR INVASION;

ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME REPRESSION; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; ISOTHIOCYANATES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 7; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; RAS PROTEINS; RHOA GTP-BINDING PROTEIN; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84941958209     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.4260     Document Type: Article

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