메뉴 건너뛰기




Volumn 6, Issue , 2015, Pages 421-425

Treatment of sunitinib-induced hypertension in solid tumor by nitric oxide donors

Author keywords

Hypertension; Nitric oxide; Renal cell carcinoma; Sunitinib; Tyrosine kinase inhibitors; Vascular endothelial growth factor

Indexed keywords

ENDOTHELIN 1; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SUNITINIB; VASCULOTROPIN; ANTIHYPERTENSIVE AGENT; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; PYRROLE DERIVATIVE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

EID: 84941945951     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2015.09.007     Document Type: Article
Times cited : (24)

References (40)
  • 1
    • 33846164111 scopus 로고    scopus 로고
    • Renal-cell carcinoma-molecular pathways and therapies
    • Brugarolas J. Renal-cell carcinoma-molecular pathways and therapies. N. Engl. J. Med. 2007, 356(2):185-187.
    • (2007) N. Engl. J. Med. , vol.356 , Issue.2 , pp. 185-187
    • Brugarolas, J.1
  • 2
    • 52049106205 scopus 로고    scopus 로고
    • The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway
    • Roodhart J.M., Langenberg M.H., Witteveen E., Voest E.E. The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway. Curr. Clin. Pharmacol. 2008, 3(2):132-143.
    • (2008) Curr. Clin. Pharmacol. , vol.3 , Issue.2 , pp. 132-143
    • Roodhart, J.M.1    Langenberg, M.H.2    Witteveen, E.3    Voest, E.E.4
  • 3
    • 57349138859 scopus 로고    scopus 로고
    • Hypertension and proteinuria: a class-effect of antiangiogenic therapies
    • Launay-Vacher V., Deray G. Hypertension and proteinuria: a class-effect of antiangiogenic therapies. Anticancer Drugs 2009, 20(1):81-82.
    • (2009) Anticancer Drugs , vol.20 , Issue.1 , pp. 81-82
    • Launay-Vacher, V.1    Deray, G.2
  • 4
    • 84874556222 scopus 로고    scopus 로고
    • Malignant hypertension in patients treated with vascular endothelial growth factor inhibitors
    • Caro J., Morales E., Gutierrez E., Ruilope L.M., Praga M. Malignant hypertension in patients treated with vascular endothelial growth factor inhibitors. J. Clin. Hypertens. (Greenwich) 2013, 15(3):215-216.
    • (2013) J. Clin. Hypertens. (Greenwich) , vol.15 , Issue.3 , pp. 215-216
    • Caro, J.1    Morales, E.2    Gutierrez, E.3    Ruilope, L.M.4    Praga, M.5
  • 6
    • 0030022917 scopus 로고    scopus 로고
    • Effects of vascular endothelial growth factor on hemodynamics and cardiac performance
    • Yang R., Thomas G.R., Bunting S., Ko A., Ferrara N., Keyt B., et al. Effects of vascular endothelial growth factor on hemodynamics and cardiac performance. J. Cardiovasc. Pharmacol. 1996, 27(6):838-844.
    • (1996) J. Cardiovasc. Pharmacol. , vol.27 , Issue.6 , pp. 838-844
    • Yang, R.1    Thomas, G.R.2    Bunting, S.3    Ko, A.4    Ferrara, N.5    Keyt, B.6
  • 7
    • 50349101200 scopus 로고    scopus 로고
    • Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor
    • Steeghs N., Gelderblom H., Roodt J.O., Christensen O., Rajagopalan P., Hovens M., et al. Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor. Clin. Cancer Res. 2008, 14(11):3470-3476.
    • (2008) Clin. Cancer Res. , vol.14 , Issue.11 , pp. 3470-3476
    • Steeghs, N.1    Gelderblom, H.2    Roodt, J.O.3    Christensen, O.4    Rajagopalan, P.5    Hovens, M.6
  • 8
    • 84858701414 scopus 로고    scopus 로고
    • Sunitinib: the first to arrive at first-line metastatic renal cell carcinoma
    • Vázquez S., León L., Fernández O., Lázaro M., Grande E., Aparicio L. Sunitinib: the first to arrive at first-line metastatic renal cell carcinoma. Adv. Ther. 2012, 29(3):202-217.
    • (2012) Adv. Ther. , vol.29 , Issue.3 , pp. 202-217
    • Vázquez, S.1    León, L.2    Fernández, O.3    Lázaro, M.4    Grande, E.5    Aparicio, L.6
  • 10
    • 68949145218 scopus 로고    scopus 로고
    • Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
    • Motzer R.J., Hutson T.E., Tomczak P., Michaelson M.D., Bukowski R.M., Oudard S., et al. Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J. Clin. Oncol. 2009, 27(22):3584-3590.
    • (2009) J. Clin. Oncol. , vol.27 , Issue.22 , pp. 3584-3590
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3    Michaelson, M.D.4    Bukowski, R.M.5    Oudard, S.6
  • 11
    • 67651201656 scopus 로고    scopus 로고
    • Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial
    • Gore M.E., Szczylik C., Porta C., Bracarda S., Bjarnason G.A., Oudard S., et al. Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial. Lancet Oncol. 2009, 10(8):757-763.
    • (2009) Lancet Oncol. , vol.10 , Issue.8 , pp. 757-763
    • Gore, M.E.1    Szczylik, C.2    Porta, C.3    Bracarda, S.4    Bjarnason, G.A.5    Oudard, S.6
  • 12
    • 0035130107 scopus 로고    scopus 로고
    • Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
    • Taraseviciene-Stewart L., Kasahara Y., Alger L., Hirth P., Mc Mahon G., Waltenberger J., et al. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J. 2001, 15(2):427-438.
    • (2001) FASEB J. , vol.15 , Issue.2 , pp. 427-438
    • Taraseviciene-Stewart, L.1    Kasahara, Y.2    Alger, L.3    Hirth, P.4    Mc Mahon, G.5    Waltenberger, J.6
  • 13
    • 0031471950 scopus 로고    scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor produces nitric oxide-dependent hypotension. Evidence for a maintenance role in quiescent adult endothelium
    • Horowitz J.R., Rivard A., van der Zee R., Hariawala M., Sheriff D.D., Esakof D.D., et al. Vascular endothelial growth factor/vascular permeability factor produces nitric oxide-dependent hypotension. Evidence for a maintenance role in quiescent adult endothelium. Arterioscler. Thromb. Vasc. Biol. 1997, 17(11):2793-2800.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , Issue.11 , pp. 2793-2800
    • Horowitz, J.R.1    Rivard, A.2    van der Zee, R.3    Hariawala, M.4    Sheriff, D.D.5    Esakof, D.D.6
  • 14
    • 58149098429 scopus 로고    scopus 로고
    • Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: systematic review and meta-analysis
    • Zhu X., Stergiopoulos K., Wu S. Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: systematic review and meta-analysis. Acta Oncol. 2009, 48(1):9-17.
    • (2009) Acta Oncol. , vol.48 , Issue.1 , pp. 9-17
    • Zhu, X.1    Stergiopoulos, K.2    Wu, S.3
  • 16
    • 0034961996 scopus 로고    scopus 로고
    • Physiological antagonism of endothelin-1 in human conductance and resistance coronary artery
    • Wiley K.E., Davenport A.P. Physiological antagonism of endothelin-1 in human conductance and resistance coronary artery. Br. J. Pharmacol. 2001, 133(4):568-574.
    • (2001) Br. J. Pharmacol. , vol.133 , Issue.4 , pp. 568-574
    • Wiley, K.E.1    Davenport, A.P.2
  • 17
    • 77957231200 scopus 로고    scopus 로고
    • Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels
    • Kappers M.H.W., van Esch J.H.M., Sluiter W., Sleijfer S., Danser A.H.J., van den Meiracker A.H. Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels. Hypertension 2010, 56(4):675-681.
    • (2010) Hypertension , vol.56 , Issue.4 , pp. 675-681
    • Kappers, M.H.W.1    van Esch, J.H.M.2    Sluiter, W.3    Sleijfer, S.4    Danser, A.H.J.5    van den Meiracker, A.H.6
  • 19
    • 84866594257 scopus 로고    scopus 로고
    • Polymorphisms in endothelial nitric oxide synthase (enos) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension
    • Eechoute K., van der Veldt A.A.M., Oosting S., Kappers M.H.W., Wessels J.A.M., Gelderblom H., et al. Polymorphisms in endothelial nitric oxide synthase (enos) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension. Clin. Pharmacol. Ther. 2012, 92(4):503-510.
    • (2012) Clin. Pharmacol. Ther. , vol.92 , Issue.4 , pp. 503-510
    • Eechoute, K.1    van der Veldt, A.A.M.2    Oosting, S.3    Kappers, M.H.W.4    Wessels, J.A.M.5    Gelderblom, H.6
  • 20
    • 0032504745 scopus 로고    scopus 로고
    • Fluid shear stress stimulates phosphorylation of akt in human endothelial cells: involvement in suppression of apoptosis
    • Dimmeler S., Assmus B., Hermann C., Haendeler J., Zeiher A.M. Fluid shear stress stimulates phosphorylation of akt in human endothelial cells: involvement in suppression of apoptosis. Circ. Res. 1998, 83(3):334-341.
    • (1998) Circ. Res. , vol.83 , Issue.3 , pp. 334-341
    • Dimmeler, S.1    Assmus, B.2    Hermann, C.3    Haendeler, J.4    Zeiher, A.M.5
  • 21
    • 63049088767 scopus 로고    scopus 로고
    • Renal effects of anti-angiogenesis therapy: update for the internist
    • Gurevich F., Perazella M.A. Renal effects of anti-angiogenesis therapy: update for the internist. Am. J. Med. 2009, 122(4):322-328.
    • (2009) Am. J. Med. , vol.122 , Issue.4 , pp. 322-328
    • Gurevich, F.1    Perazella, M.A.2
  • 22
    • 0030949484 scopus 로고    scopus 로고
    • Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure
    • Noon J.P., Walker B.R., Webb D.J., Shore A.C., Holton D.W., Edwards H.V., Watt G.C. Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure. J. Clin. Invest. 1997, 99(8):1873-1879.
    • (1997) J. Clin. Invest. , vol.99 , Issue.8 , pp. 1873-1879
    • Noon, J.P.1    Walker, B.R.2    Webb, D.J.3    Shore, A.C.4    Holton, D.W.5    Edwards, H.V.6    Watt, G.C.7
  • 23
    • 0031878495 scopus 로고    scopus 로고
    • Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression
    • Matsuura A., Yamochi W., Hirata K., Kawashima S., Yokoyama M. Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression. Hypertension 1998, 32(1):89-95.
    • (1998) Hypertension , vol.32 , Issue.1 , pp. 89-95
    • Matsuura, A.1    Yamochi, W.2    Hirata, K.3    Kawashima, S.4    Yokoyama, M.5
  • 24
    • 0037370325 scopus 로고    scopus 로고
    • Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
    • Eremina V., Sood M., Haigh J., Nagy A., Lajoie G., Ferrara N., et al. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J. Clin. Invest. 2003, 111(5):707-716.
    • (2003) J. Clin. Invest. , vol.111 , Issue.5 , pp. 707-716
    • Eremina, V.1    Sood, M.2    Haigh, J.3    Nagy, A.4    Lajoie, G.5    Ferrara, N.6
  • 25
    • 0023756850 scopus 로고
    • The discovery of nitric oxide as the endogenous nitrovasodilator
    • Moncada S., Palmer R.M., Higgs E.A. The discovery of nitric oxide as the endogenous nitrovasodilator. Hypertension 1988, 12(4):365-372.
    • (1988) Hypertension , vol.12 , Issue.4 , pp. 365-372
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 26
    • 0027752805 scopus 로고
    • The l-arginine-nitric oxide pathway
    • Moncada S., Higgs A. The l-arginine-nitric oxide pathway. N. Engl. J. Med. 1993, 329(27):2002-2012.
    • (1993) N. Engl. J. Med. , vol.329 , Issue.27 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 27
    • 0028863627 scopus 로고
    • Molecular mechanisms and therapeutic strategies related to nitric oxide
    • Moncada S., Higgs E.A. Molecular mechanisms and therapeutic strategies related to nitric oxide. FASEB J. 1995, 9(13):1319-1330.
    • (1995) FASEB J. , vol.9 , Issue.13 , pp. 1319-1330
    • Moncada, S.1    Higgs, E.A.2
  • 30
    • 0033916814 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase (inos) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate
    • Kibbe M.R., Li J., Nie S., Watkins S.C., Lizonova A., Kovesdi I., et al. Inducible nitric oxide synthase (inos) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate. J. Vasc. Surg. 2000, 31(6):1214-1228.
    • (2000) J. Vasc. Surg. , vol.31 , Issue.6 , pp. 1214-1228
    • Kibbe, M.R.1    Li, J.2    Nie, S.3    Watkins, S.C.4    Lizonova, A.5    Kovesdi, I.6
  • 31
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung D.W., Cachianes G., Kuang W.J., Goeddel D.V., Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989, 246(4935):1306-1309.
    • (1989) Science , vol.246 , Issue.4935 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 32
    • 0029021660 scopus 로고
    • Role of the flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong G.H., Rossant J., Gertsenstein M., Breitman M.L. Role of the flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 1995, 376(6535):66-70.
    • (1995) Nature , vol.376 , Issue.6535 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 33
    • 70349249625 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression
    • Facemire C.S., Nixon A.B., Griffiths R., Hurwitz H., Coffman T.M. Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression. Hypertension 2009, 54(3):652-658.
    • (2009) Hypertension , vol.54 , Issue.3 , pp. 652-658
    • Facemire, C.S.1    Nixon, A.B.2    Griffiths, R.3    Hurwitz, H.4    Coffman, T.M.5
  • 35
    • 34250350040 scopus 로고    scopus 로고
    • Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the european society of hypertension (ESH) and of the european society of cardiology (ESC)
    • Mancia G., De Backer G., Dominiczak A., Cifkova R., Fagard R., Germano G., et al. guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the european society of hypertension (ESH) and of the european society of cardiology (ESC). J. Hypertens. 2007 2007, 25(6):1105-1187.
    • (2007) J. Hypertens. 2007 , vol.25 , Issue.6 , pp. 1105-1187
    • Mancia, G.1    De Backer, G.2    Dominiczak, A.3    Cifkova, R.4    Fagard, R.5    Germano, G.6
  • 37
    • 77952881390 scopus 로고    scopus 로고
    • Management of sunitinib-related adverse events: an evidence- and expert-based consensus approach
    • Grünwald V., Kalanovic D., Merseburger A.S. Management of sunitinib-related adverse events: an evidence- and expert-based consensus approach. World J. Urol. 2010, 28(3):343-351.
    • (2010) World J. Urol. , vol.28 , Issue.3 , pp. 343-351
    • Grünwald, V.1    Kalanovic, D.2    Merseburger, A.S.3
  • 39
    • 84879507881 scopus 로고    scopus 로고
    • Therapeutic potential of nitric oxide donors in the prevention and treatment of angiogenesis-inhibitor-induced hypertension
    • Kruzliak P., Kovacova G., Pechanova O. Therapeutic potential of nitric oxide donors in the prevention and treatment of angiogenesis-inhibitor-induced hypertension. Angiogenesis 2013, 16(2):289-295.
    • (2013) Angiogenesis , vol.16 , Issue.2 , pp. 289-295
    • Kruzliak, P.1    Kovacova, G.2    Pechanova, O.3
  • 40
    • 84890455222 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibitor-induced hypertension: from pathophysiology to prevention and treatment based on long-acting nitric oxide donors
    • Kruzliak P., Novák J., Novák M. Vascular endothelial growth factor inhibitor-induced hypertension: from pathophysiology to prevention and treatment based on long-acting nitric oxide donors. Am. J. Hypertens. 2014, 27(1):3-13.
    • (2014) Am. J. Hypertens. , vol.27 , Issue.1 , pp. 3-13
    • Kruzliak, P.1    Novák, J.2    Novák, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.