Effects of vascular endothelial growth factor on hemodynamics and cardiac performance

Journal of Cardiovascular Pharmacology

Volumn 27, Issue 6, 1996, Pages 838-844

  Yang, Renhui ^a   Thomas, G Roger ^a   Bunting, Stuart ^a   Ko, Annie ^a   Ferrara, Napoleone ^a   Keyt, Bruce ^a   Ross, Jed ^a   Jin, Hongkui ^a  

^a GENENTECH INC   (United States)

Author keywords

Cardiac function; Growth factor; Hemodynamics; Nitric oxide; Vascular endothelial growth factor

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; RECOMBINANT VASCULOTROPIN; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DEPRESSOR RESPONSE; DOSE RESPONSE; HEART HEMODYNAMICS; HEART LEFT VENTRICLE DP-DT; HEART MUSCLE CONTRACTILITY; HEART OUTPUT; HEART STROKE VOLUME; HEMATOCRIT; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; TACHYCARDIA;

ANIMALS; CARDIOTONIC AGENTS; ENDOTHELIAL GROWTH FACTORS; HEART; HEMODYNAMIC PROCESSES; LYMPHOKINES; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0030022917     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199606000-00011     Document Type: Article

References (30)

1. Ferrara N, Henzel WJ. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 1989;161: 851-8.
2. Connolly DT, Heuvelman D, Nelson R, et al. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 1989;84:1470-8.
3. Connolly DT, Olander JV, Heuvelman D, et al. Human vascular permeability factor. Isolation from U937 cells. J Biol Chem 1989;264:20017-24.
4. Keck PJ, Hauser SD, Krivi G, et al. Vascular permeability factor, an endothelial mitogen related to PDGF. Science 1989;246:1309-12.
5. Tischer E, Mitchell R, Hartmen T, et al. The human gene for vascular endothelial growth factor: multiple protein forms are encoded through alternative exon splicing. J Biol Chem 1991;266:11947-54.
6. Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989;246:1306-9.
7. Houck KA, Ferrara N, Winer J, Cachianes G, Li B, Leung DW. The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol 1991;5: 1806-14.
8. Phillips HS, Hains J, Lenug DW, Ferrara N. Vascular endothelial growth factor is expressed in rat corpus luteum. Endocrinology 1990;127:965-8.
9. Breier G, Albrecht U, Sterrer S, Risau W. Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development 1992;114:521-32.
10. Jakeman LB, Winer J, Bennett GL, Altar CA, Ferrara N. Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues. J Clin Invest 1992;89:244-53.
11. de Vries C, Escobedo JA, Ueno H, Houck KA, Ferrara N, Williams LT. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 1992;255: 989-91.
12. Terman BI, Vermazen MD, Carrion ME, et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial growth factor. Biochem Biophys Res Commun 1992; 34:1578-86.
13. Quinn T, Peters KG, de Viries C, Ferrara N, Williams LT. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelial. Proc Natl Acad Sci USA 1993;90:7533-7.
14. Takeshita S, Zheng LP, Brogi E, et al. Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J Clin Invest 1994;93:662-70.
15. Banai S, Jaklitsch MT, Shou M, et al. Angiogenic-induced endothelial enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs. Circulation 1994;89:2183-9.
16. Ku DD, Zaleski JK, Liu S, Brock TA. Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries. Am J Physiol 1993;265 (Heart Circ Physiol 34):H585-92.
17. Ferrara N, Leung DW, Cachianes G, Winer J, Henzel WJ. Purification and cloning of vascular endothelial growth factor secreted by pituitary folliculostellate cells. Methods Enzymol 1991;198:391-404.
18. Pfeffer JM, Pfeffer MA, Braunwald E. Influence of chronic captopril therapy on the infarcted left ventricle of the rat. Circ Res 1985;57:84-95.
19. Buttrick P Perla C, Malhotra A, Geenen D, Lahorra M, Scheuer J. Effects of chronic dobutamine on cardiac mechanics and biochemistry after myocardial infarction. Am J Physiol 1991;260 (Hear Circ Physiol 29):H473-9.
20. Buttrick P Perla C, Malhotra A, Geenen D, Lahorra M, Scheuer J. Effects of chronic dobutamine on cardiac mechanics and biochemistry after myocardial infarction. Am J Physiol 1991;260 (Hear Circ Physiol 29):H473-9.
21. Yang RH, Bunting S, Gillett N, Clark RG, Jin H. Effects of growth hormone in rats with postinfarction left ventricular dysfunction. Cardiovasc Drugs Ther 1995;9:125-31.
22. Ferrara N, Houck K, Jakeman L, Leung DW. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocrinol Rev 1992;13:18-32.
23. Bikfalvi A, Sauzeau C, Moukadiri H, et al. Interaction of vasculotropin/vascular endothelial growth factor with human umbilical endothelial cells: binding, internalization, degradation, and biological effects. J Cell Physiol 1991;149: 50-9.
24. Gitay-Goren H, Soker S, Vlodasky I, Neufeld G. The binding of vascular endothelial growth factor to its receptors is dependent on cell surface associated heparin-like molecules. J Biol Chem 1992;267:6093-8.
25. Myoken Y, Kayada Y, Okamoto T, Kan M, Sato GH, Sato JD. Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites. Proc Natl Acad Sci USA 1991;88:5819-23.
26. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43:109-42.
27. Thomas GR, Thiemermann C, Walder C, Vane JR. The effects of endothelium-dependent vasodilators on cardiac output and their distribution in the anesthetized rat: a comparison with sodium nitroprusside. Br J Pharmacol 1988;95: 986-92.
28. Fouler H, Covell JW, Ross J. Effects of nitroprusside on venous return and central blood volume in absence and presence of acute heart failure. Circulation 1980;61:328-36.
29. Senger DR, Galli SJ, Dvorak AM, Peruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983;219:983-5.
30. Senger DR, Perruzzi CA, Feder J, Dvorak HF. A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines. Cancer Res 1986;46: 5629-32.