P2X7 receptor as predictor gene for glioma radiosensitivity and median survival

International Journal of Biochemistry and Cell Biology

Volumn 68, Issue , 2015, Pages 92-100

  Gehring, Marina P ^a   Kipper, Franciele ^b   Nicoletti, Natália F ^a   Sperotto, Nathalia D ^a   Zanin, Rafael ^a   Tamajusuku, Alessandra S K ^b   Flores, Debora G ^c   Meurer, Luise ^c   Roesler, Rafael ^b,c,d   Filho, Aroldo B ^a   Lenz, Guido ^b   Campos, Maria M ^a   Morrone, Fernanda B ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^d National Institute for Translational Medicine   (Brazil)

Author keywords

ATP; Glioma; Median survival; P2X7 receptor; Radiotherapy

Indexed keywords

ADENOSINE TRIPHOSPHATE; ETHIDIUM BROMIDE; LIPOCORTIN 5; PURINERGIC P2X7 RECEPTOR; ETHIDIUM; P2XR RECEPTOR, HUMAN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; GAMMA RADIATION; GENE; GLIOMA; GLIOMA CELL LINE; HUMAN; HUMAN CELL; IN VIVO STUDY; IRRADIATION; MOUSE; NONHUMAN; PREDICTOR VARIABLE; RADIOSENSITIVITY; SURVIVAL RATE; TREATMENT RESPONSE; TUMOR VOLUME; ANIMAL; BRAIN TUMOR; C57BL MOUSE; CANCER TRANSPLANTATION; CELL DEATH; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; GLIA; GLIOBLASTOMA; MALE; METABOLISM; MORTALITY; PATHOLOGY; RADIATION TOLERANCE; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANNEXIN A5; BRAIN NEOPLASMS; CELL DEATH; CELL LINE, TUMOR; ETHIDIUM; GAMMA RAYS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLIOBLASTOMA; HUMANS; MALE; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; NEUROGLIA; RADIATION TOLERANCE; RECEPTORS, PURINERGIC P2X7; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS;

EID: 84941945360     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2015.09.001     Document Type: Article

References (49)

1. E. Adinolfi, M. Cirillo, R. Woltersdorf, S. Falzoni, P. Chiozzi, P. Pellegatti, and et al. Trophic activity of a naturally occurring truncated isoform of the P2X7 receptor FASEB J. 24 2010 3393 3404
2. E. Adinolfi, L. Raffaghello, A.L. Giuliani, L. Cavazzini, M. Capece, P. Chiozzi, and et al. Expression of P2X7 receptor increases in vivo tumor growth Cancer Res. 72 2012 2957 2969
3. C. Bassi, S.S. Mello, R.S. Cardoso, P.D. Godoy, A.L. Fachin, C.M. Junta, and et al. Transcriptional changes in U343 MG-a glioblastoma cell line exposed to ionizing radiation Hum. Exp. Toxicol. 27 2008 919 929
4. S. Bian, X. Sun, A. Bai, C. Zhang, L. Li, K. Enjyoji, and et al. P2X7 integrates PI3K/AKT and AMPK-PRAS40-mTOR signaling pathways to mediate tumor cell death PLOS ONE 8 2013 e60184
5. L. Boldrini, M. Giordano, G. Ali, F. Melfi, G. Romano, M. Lucchi, and et al. P2X7 mRNA expression in non-small cell lung cancer: microRNA regulation and prognostic value Oncol. Lett. 9 2015 449 453
6. E. Braganhol, F.B. Morrone, A. Bernardi, D. Huppes, L. Meurer, M.I. Edelweiss, and et al. Selective NTPDase2 expression modulates in vivo rat glioma growth Cancer Sci. 100 2009 1434 1442
7. G. Burnstock, and F. Di Virgilio Purinergic signalling and cancer Purinergic Signal. 2013
8. S.R. Chandana, S. Movva, M. Arora, and T. Singh Primary brain tumors in adults Am. Fam. Physician 77 2008 1423 1430
9. J. Cote, V. Bovenzi, M. Savard, C. Dubuc, A. Fortier, W. Neugebauer, and et al. Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin B1 receptor agonist in a glioma rat model PLoS ONE 7 2012 e37485
10. S. Daido, A. Yamamoto, K. Fujiwara, R. Sawaya, S. Kondo, and Y. Kondo Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy Cancer Res. 65 2005 4368 4375
11. F. Di Virgilio Purines, purinergic receptors, and cancer Cancer Res. 72 2012 5441 5447
12. F. Di Virgilio, D. Ferrari, and E. Adinolfi P2X(7): a growth-promoting receptor-implications for cancer Purinergic Signal. 5 2009 251 256
13. J. Fang, X. Chen, L. Zhang, J. Chen, Y. Liang, X. Li, and et al. P2X7R suppression promotes glioma growth through epidermal growth factor receptor signal pathway Int. J. Biochem. Cell Biol. 45 2013 1109 1120
14. J.L. Fisher, J.A. Schwartzbaum, M. Wrensch, and J.L. Wiemels Epidemiology of brain tumors Neurol. Clin. 25 2007 867 890 vii
15. W. Fu, T. McCormick, X. Qi, L. Luo, L. Zhou, X. Li, and et al. Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice BMC Cancer 9 2009 114
16. F.B. Furnari, T. Fenton, R.M. Bachoo, A. Mukasa, J.M. Stommel, A. Stegh, and et al. Malignant astrocytic glioma: genetics, biology, and paths to treatment Genes Dev. 21 2007 2683 2710
17. L. Galluzzi, O. Kepp, and G. Kroemer Immunogenic cell death in radiation therapy Oncoimmunology 2 2013 e26536
18. M.P. Gehring, T.C. Pereira, R.F. Zanin, M.C. Borges, A. Braga Filho, A.M. Battastini, and et al. P2X7 receptor activation leads to increased cell death in a radiosensitive human glioma cell line Purinergic Signal. 8 2012 729 739
19. F. Ghiringhelli, L. Apetoh, A. Tesniere, L. Aymeric, Y. Ma, C. Ortiz, and et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors Nat. Med. 15 2009 1170 1178
20. B.S. Hoppe, R.B. Jensen, and C.U. Kirchgessner Complementation of the radiosensitive M059J cell line Radiat. Res. 153 2000 125 130
21. B. Jelassi, A. Chantome, F. Alcaraz-Perez, A. Baroja-Mazo, M.L. Cayuela, P. Pelegrin, and et al. P2X(7) receptor activation enhances SK3 channels- and cystein cathepsin-dependent cancer cells invasiveness Oncogene 30 2011 2108 2122
22. G. Kroemer, L. Galluzzi, O. Kepp, and L. Zitvogel Immunogenic cell death in cancer therapy Annu. Rev. Immunol. 31 2013 51 72
23. T. Lindgren, T. Stigbrand, K. Riklund, L. Johansson, and D. Eriksson Gene expression profiling in MOLT-4 cells during gamma-radiation-induced apoptosis Tumour Biol. 33 2012 689 700
24. H. Ma, L. Rao, H.L. Wang, Z.W. Mao, R.H. Lei, Z.Y. Yang, and et al. Transcriptome analysis of glioma cells for the dynamic response to gamma-irradiation and dual regulation of apoptosis genes: a new insight into radiotherapy for glioblastomas Cell Death Dis. 4 2013 e895
25. Y. Ma, S. Adjemian, S.R. Mattarollo, T. Yamazaki, L. Aymeric, H. Yang, and et al. Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells Immunity 38 2013 729 741
26. D. Mathieu, and D. Fortin The role of chemotherapy in the treatment of malignant astrocytomas Can. J. Neurol. Sci. 33 2006 127 140
27. F.B. Morrone, M.C. Jacques-Silva, A.P. Horn, A. Bernardi, G. Schwartsmann, R. Rodnight, and et al. Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines J. Neurooncol. 64 2003 211 218
28. F.B. Morrone, D.L. Oliveira, P. Gamermann, J. Stella, S. Wofchuk, M.R. Wink, and et al. In vivo glioblastoma growth is reduced by apyrase activity in a rat glioma model BMC Cancer 6 2006 226
29. E.W. Newcomb, Y. Lukyanov, N. Kawashima, M. Alonso-Basanta, S.C. Wang, M. Liu, and et al. Radiotherapy enhances antitumor effect of anti-CD137 therapy in a mouse Glioma model Radiat. Res. 173 2010 426 432
30. C. Nieder, M.P. Mehta, and R. Jalali Combined radio- and chemotherapy of brain tumours in adult patients Clin. Oncol. (R. Coll. Radiol.) 21 2009 515 524
31. Y. Ohshima, M. Tsukimoto, T. Takenouchi, H. Harada, A. Suzuki, M. Sato, and et al. gamma-Irradiation induces P2X(7) receptor-dependent ATP release from B16 melanoma cells Biochim. Biophys. Acta 1800 2010 40 46
32. Y. Qiu, W.H. Li, H.Q. Zhang, Y. Liu, X.X. Tian, and W.G. Fang P2X7 mediates ATP-driven invasiveness in prostate cancer cells PLOS ONE 9 2014 e114371
33. F. Rassendren, G.N. Buell, C. Virginio, G. Collo, R.A. North, and A. Surprenant The permeabilizing ATP receptor, P2X7. Cloning and expression of a human cDNA J. Biol. Chem. 272 1997 5482 5486
34. N. Riteau, P. Gasse, L. Fauconnier, A. Gombault, M. Couegnat, L. Fick, and et al. Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis Am. J. Respir. Crit. Care Med. 182 2010 774 783
35. S. Roger, and P. Pelegrin P2X7 receptor antagonism in the treatment of cancers Expert Opin. Investig. Drugs 20 2011 875 880
36. D.A. Smirnov, L. Brady, K. Halasa, M. Morley, S. Solomon, and V.G. Cheung Genetic variation in radiation-induced cell death Genome Res. 22 2012 332 339
37. A. Surprenant, F. Rassendren, E. Kawashima, R.A. North, and G. Buell The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7) Science 272 1996 735 738
38. T. Szatmari, K. Lumniczky, S. Desaknai, S. Trajcevski, E.J. Hidvegi, H. Hamada, and et al. Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy Cancer Sci. 97 2006 546 553
39. A.S. Tamajusuku, E.S. Villodre, R. Paulus, R. Coutinho-Silva, A.M. Battasstini, M.R. Wink, and et al. Characterization of ATP-induced cell death in the GL261 mouse glioma J. Cell. Biochem. 109 2010 983 991
40. L. Ulmann, H. Hirbec, and F. Rassendren P2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory pain EMBO J. 29 2010 2290 2300
41. E.G. Van Meir, C.G. Hadjipanayis, A.D. Norden, H.K. Shu, P.Y. Wen, and J.J. Olson Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma CA Cancer J. Clin. 60 2010 166 193
42. S. Vinchon-Petit, D. Jarnet, E. Jadaud, L. Feuvret, E. Garcion, and P. Menei External irradiation models for intracranial 9L glioma studies J. Exp. Clin. Cancer Res. 29 2010 142
43. P. Virsik-Kopp, M. Rave-Frank, H. Hofman-Huther, and H. Schmidberger Role of DNA-PK in the process of aberration formation as studied in irradiated human glioblastoma cell lines M059K and M059J Int. J. Radiat. Biol. 79 2003 61 68
44. Q. Wang, L. Wang, Y.H. Feng, X. Li, R. Zeng, and G.I. Gorodeski P2X7 receptor-mediated apoptosis of human cervical epithelial cells Am. J. Physiol.: Cell Physiol. 287 2004 1349C 1358C
45. S. Wang, Y. Chen, B. Lal, E. Ford, E. Tryggestad, M. Armour, and et al. Evaluation of radiation necrosis and malignant glioma in rat models using diffusion tensor MR imaging J. Neurooncol. 107 2012 51 60
46. N. White, and G. Burnstock P2 receptors and cancer Trends Pharmacol. Sci. 27 2006 211 217
47. N. White, P.E. Butler, and G. Burnstock Human melanomas express functional P2 X(7) receptors Cell Tissue Res. 321 2005 411 418
48. J. Xia, X. Yu, L. Tang, G. Li, and T. He P2X7 receptor stimulates breast cancer cell invasion and migration via the AKT pathway Oncol. Rep. 34 2015 103 110
49. I. Yang, N.G. Huh, Z.A. Smith, S.J. Han, and A.T. Parsa Distinguishing glioma recurrence from treatment effect after radiochemotherapy and immunotherapy Neurosurg. Clin. North Am. 21 2010 181 186