-
2
-
-
84883028739
-
Stereotactic ablative radiotherapy in the UK: current status and developments
-
Jain P., Baker A., Distefano G., et al. Stereotactic ablative radiotherapy in the UK: current status and developments. Br. J. Radiol 2013, 86:20130331.
-
(2013)
Br. J. Radiol
, vol.86
-
-
Jain, P.1
Baker, A.2
Distefano, G.3
-
3
-
-
84859843601
-
Outcomes of stereotactic ablative radiotherapy in patients with potentially operable stage I non-small cell lung cancer
-
Lagerwaard F.J., Verstegen N.E., Haasbeek C.J., et al. Outcomes of stereotactic ablative radiotherapy in patients with potentially operable stage I non-small cell lung cancer. Int. J. Radiat. Oncol. Biol. Phys 2012, 83:348-353.
-
(2012)
Int. J. Radiat. Oncol. Biol. Phys
, vol.83
, pp. 348-353
-
-
Lagerwaard, F.J.1
Verstegen, N.E.2
Haasbeek, C.J.3
-
4
-
-
81855203431
-
Stereotactic body radiotherapy (SBRT) for operable stage I non-small-cell lung cancer: can SBRT be comparable to surgery?
-
Onishi H., Shirato H., Nagata Y., et al. Stereotactic body radiotherapy (SBRT) for operable stage I non-small-cell lung cancer: can SBRT be comparable to surgery?. Int. J. Radiat. Oncol. Biol. Phys 2011, 81:1352-1358.
-
(2011)
Int. J. Radiat. Oncol. Biol. Phys
, vol.81
, pp. 1352-1358
-
-
Onishi, H.1
Shirato, H.2
Nagata, Y.3
-
5
-
-
84871828017
-
Stereotactic body radiotherapy for oligometastases
-
Tree A.C., Khoo V.S., Eeles R.A., et al. Stereotactic body radiotherapy for oligometastases. Lancet Oncol 2013, 14:e28-e37.
-
(2013)
Lancet Oncol
, vol.14
, pp. e28-e37
-
-
Tree, A.C.1
Khoo, V.S.2
Eeles, R.A.3
-
6
-
-
84856376628
-
Curative treatment of Stage I non-small-cell lung cancer in patients with severe COPD: stereotactic radiotherapy outcomes and systematic review
-
Palma D., Lagerwaard F., Rodrigues G., et al. Curative treatment of Stage I non-small-cell lung cancer in patients with severe COPD: stereotactic radiotherapy outcomes and systematic review. Int. J. Radiat. Oncol. Biol. Phys 2012, 82:1149-1156.
-
(2012)
Int. J. Radiat. Oncol. Biol. Phys
, vol.82
, pp. 1149-1156
-
-
Palma, D.1
Lagerwaard, F.2
Rodrigues, G.3
-
8
-
-
84872034205
-
Regional normal lung tissue density changes in patients treated with stereotactic body radiation therapy for lung tumors
-
Diot Q., Kavanagh B., Schefter T., et al. Regional normal lung tissue density changes in patients treated with stereotactic body radiation therapy for lung tumors. Int. J. Radiat. Oncol. Biol. Phys 2012, 84:1024-1030.
-
(2012)
Int. J. Radiat. Oncol. Biol. Phys
, vol.84
, pp. 1024-1030
-
-
Diot, Q.1
Kavanagh, B.2
Schefter, T.3
-
10
-
-
84865552100
-
Immuno-oncology: understanding the function and dysfunction of the immune system in cancer
-
Finn O.J. Immuno-oncology: understanding the function and dysfunction of the immune system in cancer. Ann. Oncol 2012, 23(Suppl. 8):viii6-viii9.
-
(2012)
Ann. Oncol
, vol.23
, pp. viii6-viii9
-
-
Finn, O.J.1
-
11
-
-
84859414476
-
The antitumor immunity of ipilimumab: (T-cell) memories to last a lifetime?
-
Postow M.A., Callahan M.K., Wolchok J.D. The antitumor immunity of ipilimumab: (T-cell) memories to last a lifetime?. Clin. Cancer Res 2012, 18:1821-1823.
-
(2012)
Clin. Cancer Res
, vol.18
, pp. 1821-1823
-
-
Postow, M.A.1
Callahan, M.K.2
Wolchok, J.D.3
-
12
-
-
64649084383
-
Radiation-induced bystander signalling in cancer therapy
-
Prise K.M., O'Sullivan J.M. Radiation-induced bystander signalling in cancer therapy. Nat. Rev. Cancer 2009, 9:351-360.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 351-360
-
-
Prise, K.M.1
O'Sullivan, J.M.2
-
13
-
-
84912535002
-
Non-targeted radiation effects in vivo: a critical glance of the future in radiobiology
-
Hatzi V.I., Laskaratou D.A., Mavragani I.V., et al. Non-targeted radiation effects in vivo: a critical glance of the future in radiobiology. Cancer Lett 2015, 356(1):34-42.
-
(2015)
Cancer Lett
, vol.356
, Issue.1
, pp. 34-42
-
-
Hatzi, V.I.1
Laskaratou, D.A.2
Mavragani, I.V.3
-
14
-
-
84857815877
-
Immunologic correlates of the abscopal effect in a patient with melanoma
-
Postow M.A., Callahan M.K., Barker C.A., et al. Immunologic correlates of the abscopal effect in a patient with melanoma. N. Engl. J. Med 2012, 366:925-931.
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 925-931
-
-
Postow, M.A.1
Callahan, M.K.2
Barker, C.A.3
-
15
-
-
85003053854
-
An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer
-
Golden E.B., Demaria S., Schiff P.B., et al. An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer. Cancer Immunology Research 2013, 1:365-372.
-
(2013)
Cancer Immunology Research
, vol.1
, pp. 365-372
-
-
Golden, E.B.1
Demaria, S.2
Schiff, P.B.3
-
16
-
-
84877581852
-
Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas
-
Zeng J., See A.P., Phallen J., et al. Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. Int. J. Radiat. Oncol. Biol. Phys 2013, 86:343-349.
-
(2013)
Int. J. Radiat. Oncol. Biol. Phys
, vol.86
, pp. 343-349
-
-
Zeng, J.1
See, A.P.2
Phallen, J.3
-
17
-
-
84893876109
-
Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice
-
Deng L., Liang H., Burnette B., et al. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J. Clin. Invest 2014, 124:687-695.
-
(2014)
J. Clin. Invest
, vol.124
, pp. 687-695
-
-
Deng, L.1
Liang, H.2
Burnette, B.3
-
18
-
-
0013071190
-
Whole body irradiation; radiobiology or medicine?
-
Mole R.H. Whole body irradiation; radiobiology or medicine?. Br. J. Radiol 1953, 26:234-241.
-
(1953)
Br. J. Radiol
, vol.26
, pp. 234-241
-
-
Mole, R.H.1
-
19
-
-
84902517894
-
Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death
-
Golden E.B., Frances D., Pellicciotta I., et al. Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death. OncoImmunology 2014, 3:e28518.
-
(2014)
OncoImmunology
, vol.3
-
-
Golden, E.B.1
Frances, D.2
Pellicciotta, I.3
-
20
-
-
84919475471
-
Radiation and inflammation
-
Schaue D., Micewicz E.D., Ratikan J.A., Xie M.W., Cheng G., McBride W.H. Radiation and inflammation. Semin. Radiat. Oncol 2015, 25(1):4-10.
-
(2015)
Semin. Radiat. Oncol
, vol.25
, Issue.1
, pp. 4-10
-
-
Schaue, D.1
Micewicz, E.D.2
Ratikan, J.A.3
Xie, M.W.4
Cheng, G.5
McBride, W.H.6
-
21
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T., Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011, 34(5):637-650.
-
(2011)
Immunity
, vol.34
, Issue.5
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
22
-
-
84887025705
-
Is there an oligometastatic state in non-small cell lung cancer? A systematic review of the literature
-
Ashworth A., Rodrigues G., Boldt G., Palma D. Is there an oligometastatic state in non-small cell lung cancer? A systematic review of the literature. Lung Cancer 2013, 82(2):197-203.
-
(2013)
Lung Cancer
, vol.82
, Issue.2
, pp. 197-203
-
-
Ashworth, A.1
Rodrigues, G.2
Boldt, G.3
Palma, D.4
-
24
-
-
50949098639
-
A rationale for the targeted treatment of oligometastases with radiotherapy
-
Macdermed D.M., Weichselbaum R.R., Salama J.K. A rationale for the targeted treatment of oligometastases with radiotherapy. J. Surg. Oncol 2008, 98:202-206.
-
(2008)
J. Surg. Oncol
, vol.98
, pp. 202-206
-
-
Macdermed, D.M.1
Weichselbaum, R.R.2
Salama, J.K.3
-
25
-
-
79953059789
-
Natural innate and adaptive immunity to cancer
-
Vesely M.D., Kershaw M.H., Schreiber R.D., Smyth M.J. Natural innate and adaptive immunity to cancer. Annu. Rev. Immunol 2011, 29:235-271.
-
(2011)
Annu. Rev. Immunol
, vol.29
, pp. 235-271
-
-
Vesely, M.D.1
Kershaw, M.H.2
Schreiber, R.D.3
Smyth, M.J.4
-
27
-
-
84861152022
-
Analysis of spontaneous tumor-specific CD4 T-cell immunity in lung cancer using promiscuous HLA-DR telomerase-derived epitopes: potential synergistic effect with chemotherapy response
-
Godet Y., Fabre E., Dosset M., et al. Analysis of spontaneous tumor-specific CD4 T-cell immunity in lung cancer using promiscuous HLA-DR telomerase-derived epitopes: potential synergistic effect with chemotherapy response. Clin. Cancer Res 2012, 18:2943-2953.
-
(2012)
Clin. Cancer Res
, vol.18
, pp. 2943-2953
-
-
Godet, Y.1
Fabre, E.2
Dosset, M.3
-
28
-
-
79952281183
-
Tumor immunosurveillance in human cancers
-
Mlecnik B., Bindea G., Pages F., Galon J. Tumor immunosurveillance in human cancers. Cancer Metastasis Rev 2011, 30:5-12.
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 5-12
-
-
Mlecnik, B.1
Bindea, G.2
Pages, F.3
Galon, J.4
-
29
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
Galon J., Costes A., Sanchez-Cabo F., et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006, 313:1960-1964.
-
(2006)
Science
, vol.313
, pp. 1960-1964
-
-
Galon, J.1
Costes, A.2
Sanchez-Cabo, F.3
-
30
-
-
4143141823
-
The immunobiology of cancer immunosurveillance and immunoediting
-
Dunn G.P., Old L.J., Schreiber R.D. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004, 21:137-148.
-
(2004)
Immunity
, vol.21
, pp. 137-148
-
-
Dunn, G.P.1
Old, L.J.2
Schreiber, R.D.3
-
31
-
-
84863594742
-
Cellular constituents of immune escape within the tumor microenvironment
-
Kerkar S.P., Restifo N.P. Cellular constituents of immune escape within the tumor microenvironment. Cancer Res 2012, 72:3125-3130.
-
(2012)
Cancer Res
, vol.72
, pp. 3125-3130
-
-
Kerkar, S.P.1
Restifo, N.P.2
-
32
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
33
-
-
34347395733
-
Trastuzumab - mechanism of action and use in clinical practice
-
Hudis C.A. Trastuzumab - mechanism of action and use in clinical practice. NEJM 2007, 357:39-51.
-
(2007)
NEJM
, vol.357
, pp. 39-51
-
-
Hudis, C.A.1
-
35
-
-
84880278490
-
High-dose interleukin-2: is it still indicated for melanoma and RCC in an era of targeted therapies?
-
Amin A., White R.L. High-dose interleukin-2: is it still indicated for melanoma and RCC in an era of targeted therapies?. Oncology (Williston Park) 2013, 27:680-691.
-
(2013)
Oncology (Williston Park)
, vol.27
, pp. 680-691
-
-
Amin, A.1
White, R.L.2
-
37
-
-
84869819029
-
A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma
-
Benson D.M., Hofmeister C.C., Padmanabhan S., et al. A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma. Blood 2012, 120:4324-4333.
-
(2012)
Blood
, vol.120
, pp. 4324-4333
-
-
Benson, D.M.1
Hofmeister, C.C.2
Padmanabhan, S.3
-
38
-
-
84903816506
-
Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer
-
Prendergast G.C., Smith C., Thomas S., et al. Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer. Cancer Immunol. Immunother 2014, 63:721-735.
-
(2014)
Cancer Immunol. Immunother
, vol.63
, pp. 721-735
-
-
Prendergast, G.C.1
Smith, C.2
Thomas, S.3
-
39
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff P.W., Higano C.S., Shore N.D., et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. NEJM 2010, 363:411-422.
-
(2010)
NEJM
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
40
-
-
84880730418
-
Selection of immunostimulant AS15 for active immunization with MAGE-A3 protein: results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma
-
Kruit W.H., Suciu S., Dreno B., et al. Selection of immunostimulant AS15 for active immunization with MAGE-A3 protein: results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma. J. Clin. Oncol 2013, 31:2413-2420.
-
(2013)
J. Clin. Oncol
, vol.31
, pp. 2413-2420
-
-
Kruit, W.H.1
Suciu, S.2
Dreno, B.3
-
41
-
-
84884586196
-
Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides - preclinical and clinical data
-
Vazquez A.M., Hernandez A.M., Macias A., et al. Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides - preclinical and clinical data. Front. Oncol 2012, 2:150.
-
(2012)
Front. Oncol
, vol.2
, pp. 150
-
-
Vazquez, A.M.1
Hernandez, A.M.2
Macias, A.3
-
42
-
-
48549091423
-
Allogeneic melanoma vaccine expressing alphaGal epitopes induces antitumor immunity to autologous antigens in mice without signs of toxicity
-
Rossi G.R., Mautino M.R., Awwad D.Z., et al. Allogeneic melanoma vaccine expressing alphaGal epitopes induces antitumor immunity to autologous antigens in mice without signs of toxicity. J. Immunother 2008, 31:545-554.
-
(2008)
J. Immunother
, vol.31
, pp. 545-554
-
-
Rossi, G.R.1
Mautino, M.R.2
Awwad, D.Z.3
-
43
-
-
84902137525
-
Targeting CD137 enhances the efficacy of cetuximab
-
Kohrt H.E., Colevas A.D., Houot R., et al. Targeting CD137 enhances the efficacy of cetuximab. J. Clin. Invest 2014, 124:2668-2682.
-
(2014)
J. Clin. Invest
, vol.124
, pp. 2668-2682
-
-
Kohrt, H.E.1
Colevas, A.D.2
Houot, R.3
-
44
-
-
84886945383
-
To respond or not to respond to CD40 agonism: that is the prediction
-
Shi X., Dornan D. To respond or not to respond to CD40 agonism: that is the prediction. Oncoimmunology 2012, 1:83-85.
-
(2012)
Oncoimmunology
, vol.1
, pp. 83-85
-
-
Shi, X.1
Dornan, D.2
-
45
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi F.S., O'Day S.J., McDermott D.F., et al. Improved survival with ipilimumab in patients with metastatic melanoma. NEJM 2010, 363:711-723.
-
(2010)
NEJM
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
46
-
-
84863115998
-
Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape
-
Woo S.R., Turnis M.E., Goldberg M.V., et al. Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res 2012, 72:917-927.
-
(2012)
Cancer Res
, vol.72
, pp. 917-927
-
-
Woo, S.R.1
Turnis, M.E.2
Goldberg, M.V.3
-
48
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian S.L., Hodi F.S., Brahmer J.R., et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med 2012, 366:2443-2454.
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
49
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer J.R., Tykodi S.S., Chow L.Q.M., et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. NEJM 2012, 366:2455-2465.
-
(2012)
NEJM
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.M.3
-
50
-
-
84908354848
-
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
-
Robert C., Ribas A., Wolchok J.D., et al. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet 2014, 384:1109-1117.
-
(2014)
Lancet
, vol.384
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
-
51
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
Robert C., Long G.V., Brady B., et al. Nivolumab in previously untreated melanoma without BRAF mutation. N. Engl. J. Med 2014, 372:320-330.
-
(2014)
N. Engl. J. Med
, vol.372
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
-
52
-
-
84906483079
-
Trial watch: oncolytic viruses for cancer therapy
-
Pol J., Bloy N., Obrist F., et al. Trial watch: oncolytic viruses for cancer therapy. Oncoimmunology 2014, 3:e28694.
-
(2014)
Oncoimmunology
, vol.3
-
-
Pol, J.1
Bloy, N.2
Obrist, F.3
-
53
-
-
84867313947
-
IFN-alpha in the treatment of melanoma
-
Tarhini A.A., Gogas H., Kirkwood J.M. IFN-alpha in the treatment of melanoma. J. Immunol 2012, 189:3789-3793.
-
(2012)
J. Immunol
, vol.189
, pp. 3789-3793
-
-
Tarhini, A.A.1
Gogas, H.2
Kirkwood, J.M.3
-
54
-
-
79957709717
-
Vaccines for the treatment of non-small cell lung cancer: investigational approaches and clinical experience
-
Mellstedt H., Vansteenkiste J., Thatcher N. Vaccines for the treatment of non-small cell lung cancer: investigational approaches and clinical experience. Lung Cancer 2011, 73:11-17.
-
(2011)
Lung Cancer
, vol.73
, pp. 11-17
-
-
Mellstedt, H.1
Vansteenkiste, J.2
Thatcher, N.3
-
55
-
-
84880755387
-
Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results
-
Vansteenkiste J., Zielinski M., Linder A., et al. Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results. J. Clin. Oncol 2013, 31:2396-2403.
-
(2013)
J. Clin. Oncol
, vol.31
, pp. 2396-2403
-
-
Vansteenkiste, J.1
Zielinski, M.2
Linder, A.3
-
56
-
-
84941875037
-
FDA backs continued study of belagenpumatucel-L for subgroups of patients based on data from phase III STOP trial
-
ESMO FDA backs continued study of belagenpumatucel-L for subgroups of patients based on data from phase III STOP trial. ESMO 2003, http://www.esmo.org/Conferences/Past-Conferences/European-Cancer-Congress-2013/News/Belagenpumatucel-L-Therapeutic-Tumour-Cell-Vaccine-for-Non-Small-Cell-Lung-Cancer.
-
(2003)
ESMO
-
-
-
57
-
-
67651231046
-
Immunotherapy: vaccine trials in melanoma - time for reflection
-
Eggermont A.M. Immunotherapy: vaccine trials in melanoma - time for reflection. Nat. Rev. Clin. Oncol 2009, 6:256-258.
-
(2009)
Nat. Rev. Clin. Oncol
, vol.6
, pp. 256-258
-
-
Eggermont, A.M.1
-
58
-
-
84886698315
-
Innate and adaptive immune cells in the tumor microenvironment
-
Gajewski T.F., Schreiber H., Fu Y.-X. Innate and adaptive immune cells in the tumor microenvironment. Nat. Immunol 2013, 14:1014-1022.
-
(2013)
Nat. Immunol
, vol.14
, pp. 1014-1022
-
-
Gajewski, T.F.1
Schreiber, H.2
Fu, Y.-X.3
-
59
-
-
84883863501
-
Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells
-
Spranger S., Spaapen R.M., Zha Y., et al. Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells. Sci Transl Med 2013, 5:200ra116.
-
(2013)
Sci Transl Med
, vol.5
, pp. 200-116
-
-
Spranger, S.1
Spaapen, R.M.2
Zha, Y.3
-
60
-
-
0036669785
-
The interaction properties of costimulatory molecules revisited
-
Collins A.V., Brodie D.W., Gilbert R.J.C., et al. The interaction properties of costimulatory molecules revisited. Immunity 2002, 17:201-210.
-
(2002)
Immunity
, vol.17
, pp. 201-210
-
-
Collins, A.V.1
Brodie, D.W.2
Gilbert, R.J.C.3
-
61
-
-
0032538819
-
Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells
-
Chen W., Jin W., Wahl S.M. Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells. J. Exp. Med 1998, 188:1849-1857.
-
(1998)
J. Exp. Med
, vol.188
, pp. 1849-1857
-
-
Chen, W.1
Jin, W.2
Wahl, S.M.3
-
62
-
-
23844529169
-
Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes
-
Wang J., Yoshida T., Nakaki F., et al. Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:11823-11828.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 11823-11828
-
-
Wang, J.1
Yoshida, T.2
Nakaki, F.3
-
63
-
-
84859158384
-
Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
-
Topalian S.L., Drake C.G., Pardoll D.M. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr. Opin. Immunol 2012, 24:207-212.
-
(2012)
Curr. Opin. Immunol
, vol.24
, pp. 207-212
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
64
-
-
84898843963
-
Protein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma
-
Zhang Y., Wang L., Li Y., et al. Protein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma. OncoTargets Ther 2014, 7:567-573.
-
(2014)
OncoTargets Ther
, vol.7
, pp. 567-573
-
-
Zhang, Y.1
Wang, L.2
Li, Y.3
-
65
-
-
84924902841
-
Immunologic checkpoints in cancer therapy: focus on the programmed death-1 (PD-1) receptor pathway
-
Momtaz P., Postow M.A. Immunologic checkpoints in cancer therapy: focus on the programmed death-1 (PD-1) receptor pathway. Pharmgenomics Pers. Med 2014, 7:357-365.
-
(2014)
Pharmgenomics Pers. Med
, vol.7
, pp. 357-365
-
-
Momtaz, P.1
Postow, M.A.2
-
66
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst R.S., Soria J.C., Kowanetz M., et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 2014, 515:563-567.
-
(2014)
Nature
, vol.515
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
-
67
-
-
49649114804
-
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R., Rotem-Yehudar R., Slama G., et al. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin. Cancer Res 2008, 14:3044-3051.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
-
68
-
-
84880911204
-
Abscopal [corrected] effects after conventional and stereotactic lung irradiation of non-small-cell lung cancer
-
Siva S., Callahan J., MacManus M.P., et al. Abscopal [corrected] effects after conventional and stereotactic lung irradiation of non-small-cell lung cancer. J. Thorac. Oncol 2013, 8:e71-e72.
-
(2013)
J. Thorac. Oncol
, vol.8
, pp. e71-e72
-
-
Siva, S.1
Callahan, J.2
MacManus, M.P.3
-
69
-
-
0017365178
-
Lymphangiographic demonstration of the abscopal effect in patients with malignant lymphomas
-
Antoniades J., Brady L.W., Lightfoot D.A. Lymphangiographic demonstration of the abscopal effect in patients with malignant lymphomas. Int. J. Radiat. Oncol. Biol. Phys 1977, 2:141-147.
-
(1977)
Int. J. Radiat. Oncol. Biol. Phys
, vol.2
, pp. 141-147
-
-
Antoniades, J.1
Brady, L.W.2
Lightfoot, D.A.3
-
70
-
-
7344232177
-
Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis
-
Ohba K., Omagari K., Nakamura T., et al. Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis. Gut 1998, 43:575-577.
-
(1998)
Gut
, vol.43
, pp. 575-577
-
-
Ohba, K.1
Omagari, K.2
Nakamura, T.3
-
71
-
-
0015598767
-
Abscopal effect of radiation in papillary adenocarcinoma
-
Ehlers G., Fridman M. Abscopal effect of radiation in papillary adenocarcinoma. Br. J. Radiol 1973, 46:220-222.
-
(1973)
Br. J. Radiol
, vol.46
, pp. 220-222
-
-
Ehlers, G.1
Fridman, M.2
-
72
-
-
84872202826
-
The abscopal effect associated with a systemic anti-melanoma immune response
-
Stamell E.F., Wolchok J.D., Gnjatic S., et al. The abscopal effect associated with a systemic anti-melanoma immune response. Int. J. Radiat. Oncol. Biol. Phys 2013, 85:293-295.
-
(2013)
Int. J. Radiat. Oncol. Biol. Phys
, vol.85
, pp. 293-295
-
-
Stamell, E.F.1
Wolchok, J.D.2
Gnjatic, S.3
-
73
-
-
1242315588
-
Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated
-
Demaria S., Ng B., Devitt M.L., et al. Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated. Int. J. Radiat. Oncol. Biol. Phys 2004, 58:862-870.
-
(2004)
Int. J. Radiat. Oncol. Biol. Phys
, vol.58
, pp. 862-870
-
-
Demaria, S.1
Ng, B.2
Devitt, M.L.3
-
74
-
-
67649359533
-
Systemic effects of local radiotherapy
-
Formenti S.C., Demaria S. Systemic effects of local radiotherapy. Lancet Oncol 2009, 10:718-726.
-
(2009)
Lancet Oncol
, vol.10
, pp. 718-726
-
-
Formenti, S.C.1
Demaria, S.2
-
75
-
-
21344435507
-
New insights on cell death from radiation exposure
-
Prise K.M., Schettino G., Folkard M., Held K.D. New insights on cell death from radiation exposure. Lancet Oncol 2005, 6:520-528.
-
(2005)
Lancet Oncol
, vol.6
, pp. 520-528
-
-
Prise, K.M.1
Schettino, G.2
Folkard, M.3
Held, K.D.4
-
76
-
-
77954641944
-
Radiation-induced cell death mechanisms
-
Eriksson D., Stigbrand T. Radiation-induced cell death mechanisms. Tumor Biol 2010, 31:363-372.
-
(2010)
Tumor Biol
, vol.31
, pp. 363-372
-
-
Eriksson, D.1
Stigbrand, T.2
-
77
-
-
79961098043
-
Radiation-induced bystander effects: what are they, and how relevant are they to human radiation exposures?
-
Blyth B.J., Sykes P.J. Radiation-induced bystander effects: what are they, and how relevant are they to human radiation exposures?. Radiat. Res 2011, 176:139-157.
-
(2011)
Radiat. Res
, vol.176
, pp. 139-157
-
-
Blyth, B.J.1
Sykes, P.J.2
-
78
-
-
79952702204
-
Out-of-field cell survival following exposure to intensity-modulated radiation fields
-
Butterworth K.T., McGarry C.K., Trainor C., et al. Out-of-field cell survival following exposure to intensity-modulated radiation fields. Int. J. Radiat. Oncol. Biol. Phys 2011, 79:1516-1522.
-
(2011)
Int. J. Radiat. Oncol. Biol. Phys
, vol.79
, pp. 1516-1522
-
-
Butterworth, K.T.1
McGarry, C.K.2
Trainor, C.3
-
79
-
-
84888301693
-
Implications of intercellular signaling for radiation therapy: a theoretical dose-planning study
-
McMahon S.J., McGarry C.K., Butterworth K.T., et al. Implications of intercellular signaling for radiation therapy: a theoretical dose-planning study. Int. J. Radiat. Oncol. Biol. Phys 2013, 87:1148-1154.
-
(2013)
Int. J. Radiat. Oncol. Biol. Phys
, vol.87
, pp. 1148-1154
-
-
McMahon, S.J.1
McGarry, C.K.2
Butterworth, K.T.3
-
80
-
-
36849031260
-
Sensors of ionizing radiation effects on the immunological microenvironment of cancer
-
Demaria S., Formenti S.C. Sensors of ionizing radiation effects on the immunological microenvironment of cancer. Int. J. Radiat. Biol 2007, 83:819-825.
-
(2007)
Int. J. Radiat. Biol
, vol.83
, pp. 819-825
-
-
Demaria, S.1
Formenti, S.C.2
-
81
-
-
84912524142
-
Contribution of the immune system to bystander and non-targeted effects of ionizing radiation
-
Rodel F., Frey B., Multhoff G., Gaipl U. Contribution of the immune system to bystander and non-targeted effects of ionizing radiation. Cancer Lett 2015, 356:105-113.
-
(2015)
Cancer Lett
, vol.356
, pp. 105-113
-
-
Rodel, F.1
Frey, B.2
Multhoff, G.3
Gaipl, U.4
-
82
-
-
45449090985
-
Radiation-induced IFN-γ production within the tumor microenvironment influences antitumor immunity
-
Lugade A.A., Sorensen E.W., Gerber S.A., et al. Radiation-induced IFN-γ production within the tumor microenvironment influences antitumor immunity. J. Immunol 2008, 180:3132-3139.
-
(2008)
J. Immunol
, vol.180
, pp. 3132-3139
-
-
Lugade, A.A.1
Sorensen, E.W.2
Gerber, S.A.3
-
83
-
-
20444406500
-
Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor
-
Lugade A.A., Moran J.P., Gerber S.A., et al. Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. J. Immunol 2005, 174:7516-7523.
-
(2005)
J. Immunol
, vol.174
, pp. 7516-7523
-
-
Lugade, A.A.1
Moran, J.P.2
Gerber, S.A.3
-
84
-
-
77950256166
-
Up-regulation of the pro-inflammatory chemokine CXCL16 is a common response of tumor cells to ionizing radiation
-
Matsumura S., Demaria S. Up-regulation of the pro-inflammatory chemokine CXCL16 is a common response of tumor cells to ionizing radiation. Radiat. Res 2010, 173:418-425.
-
(2010)
Radiat. Res
, vol.173
, pp. 418-425
-
-
Matsumura, S.1
Demaria, S.2
-
85
-
-
84878252530
-
In the field: exploiting the untapped potential of immunogenic modulation by radiation in combination with immunotherapy for the treatment of cancer
-
Kwilas A.R., Donahue R.N., Bernstein M.B., Hodge J.W. In the field: exploiting the untapped potential of immunogenic modulation by radiation in combination with immunotherapy for the treatment of cancer. Front. Oncol 2012, 2:104.
-
(2012)
Front. Oncol
, vol.2
, pp. 104
-
-
Kwilas, A.R.1
Donahue, R.N.2
Bernstein, M.B.3
Hodge, J.W.4
-
86
-
-
84873027802
-
Radiation survivors: understanding and exploiting the phenotype following fractionated radiation therapy
-
Makinde A.Y., John-Aryankalayil M., Palayoor S.T., et al. Radiation survivors: understanding and exploiting the phenotype following fractionated radiation therapy. Mol. Cancer Res 2013, 11:5-12.
-
(2013)
Mol. Cancer Res
, vol.11
, pp. 5-12
-
-
Makinde, A.Y.1
John-Aryankalayil, M.2
Palayoor, S.T.3
-
87
-
-
0035988623
-
Immune modulation by ionizing radiation and its implications for cancer immunotherapy
-
Friedman E.J. Immune modulation by ionizing radiation and its implications for cancer immunotherapy. Curr. Pharm. Des 2002, 8:1765-1780.
-
(2002)
Curr. Pharm. Des
, vol.8
, pp. 1765-1780
-
-
Friedman, E.J.1
-
88
-
-
33646006734
-
Signals from within: the DNA-damage-induced NF-[kappa]B response
-
Janssens S., Tschopp J. Signals from within: the DNA-damage-induced NF-[kappa]B response. Cell Death Differ 2006, 13:773-784.
-
(2006)
Cell Death Differ
, vol.13
, pp. 773-784
-
-
Janssens, S.1
Tschopp, J.2
-
89
-
-
84857542033
-
Sub-lethal irradiation of human colorectal tumor cells imparts enhanced and sustained susceptibility to multiple death receptor signaling pathways
-
Ifeadi V., Garnett-Benson C. Sub-lethal irradiation of human colorectal tumor cells imparts enhanced and sustained susceptibility to multiple death receptor signaling pathways. PLoS ONE 2012, 7:e31762.
-
(2012)
PLoS ONE
, vol.7
-
-
Ifeadi, V.1
Garnett-Benson, C.2
-
90
-
-
84875039618
-
Combining radiotherapy and cancer immunotherapy: a paradigm shift
-
Formenti S.C., Demaria S. Combining radiotherapy and cancer immunotherapy: a paradigm shift. J. Natl. Cancer Inst 2013, 105:256-265.
-
(2013)
J. Natl. Cancer Inst
, vol.105
, pp. 256-265
-
-
Formenti, S.C.1
Demaria, S.2
-
91
-
-
14744275172
-
Combination of conformal radiotherapy and intratumoral injection of adoptive dendritic cell immunotherapy in refractory hepatoma
-
Chi K.-H., Liu S.-J., Li C.-P., et al. Combination of conformal radiotherapy and intratumoral injection of adoptive dendritic cell immunotherapy in refractory hepatoma. J. Immunother 2005, 28:129-135.
-
(2005)
J. Immunother
, vol.28
, pp. 129-135
-
-
Chi, K.-H.1
Liu, S.-J.2
Li, C.-P.3
-
92
-
-
84919489297
-
Immune-maximizing (IMAX) therapy for cancer: combination of dendritic cell vaccine and intensity-modulated radiation
-
Shibamoto Y., Okamoto M., Kobayashi M., et al. Immune-maximizing (IMAX) therapy for cancer: combination of dendritic cell vaccine and intensity-modulated radiation. Mol. Clin. Oncol 2013, 1:649-654.
-
(2013)
Mol. Clin. Oncol
, vol.1
, pp. 649-654
-
-
Shibamoto, Y.1
Okamoto, M.2
Kobayashi, M.3
-
93
-
-
20944441967
-
Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer
-
Gulley J.L., Arlen P.M., Bastian A., et al. Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer. Clin. Cancer Res 2005, 11:3353-3362.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 3353-3362
-
-
Gulley, J.L.1
Arlen, P.M.2
Bastian, A.3
-
94
-
-
52649182085
-
Safety and immunologic response of a viral vaccine to prostate-specific antigen in combination with radiation therapy when metronomic-dose interleukin 2 is used as an adjuvant
-
Lechleider R.J., Arlen P.M., Tsang K.Y., et al. Safety and immunologic response of a viral vaccine to prostate-specific antigen in combination with radiation therapy when metronomic-dose interleukin 2 is used as an adjuvant. Clin. Cancer Res 2008, 14:5284-5291.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 5284-5291
-
-
Lechleider, R.J.1
Arlen, P.M.2
Tsang, K.Y.3
-
95
-
-
84899915577
-
Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients
-
Iinuma H., Fukushima R., Inaba T., et al. Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients. J. Transl. Med 2014, 12:84.
-
(2014)
J. Transl. Med
, vol.12
, pp. 84
-
-
Iinuma, H.1
Fukushima, R.2
Inaba, T.3
-
97
-
-
65349097349
-
Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells
-
Chamoto K., Takeshima T., Wakita D., et al. Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells. Cancer Sci 2009, 100:934-939.
-
(2009)
Cancer Sci
, vol.100
, pp. 934-939
-
-
Chamoto, K.1
Takeshima, T.2
Wakita, D.3
-
98
-
-
84908060936
-
Phase Ib study evaluating a self-adjuvanted mRNA cancer vaccine (RNActive(R)) combined with local radiation as consolidation and maintenance treatment for patients with stage IV non-small cell lung cancer
-
Sebastian M., Papachristofilou A., Weiss C., et al. Phase Ib study evaluating a self-adjuvanted mRNA cancer vaccine (RNActive(R)) combined with local radiation as consolidation and maintenance treatment for patients with stage IV non-small cell lung cancer. BMC Cancer 2014, 14:748.
-
(2014)
BMC Cancer
, vol.14
, pp. 748
-
-
Sebastian, M.1
Papachristofilou, A.2
Weiss, C.3
-
99
-
-
84919494209
-
Current clinical trials testing combinations of immunotherapy and radiation
-
Crittenden M., Kohrt H., Levy R., et al. Current clinical trials testing combinations of immunotherapy and radiation. Semin. Radiat. Oncol 2015, 25(1):54-64.
-
(2015)
Semin. Radiat. Oncol
, vol.25
, Issue.1
, pp. 54-64
-
-
Crittenden, M.1
Kohrt, H.2
Levy, R.3
-
102
-
-
84887561907
-
Low-dose irradiation programs macrophage differentiation to an iNOS(+)/M1 phenotype that orchestrates effective T cell immunotherapy
-
Klug F., Prakash H., Huber P.E., et al. Low-dose irradiation programs macrophage differentiation to an iNOS(+)/M1 phenotype that orchestrates effective T cell immunotherapy. Cancer Cell 2013, 24:589-602.
-
(2013)
Cancer Cell
, vol.24
, pp. 589-602
-
-
Klug, F.1
Prakash, H.2
Huber, P.E.3
-
103
-
-
69949085196
-
Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody
-
Dewan M.Z., Galloway A.E., Kawashima N., et al. Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody. Clin. Cancer Res 2009, 15:5379-5388.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 5379-5388
-
-
Dewan, M.Z.1
Galloway, A.E.2
Kawashima, N.3
-
104
-
-
84883787417
-
Immunologically augmented cancer treatment using modern radiotherapy
-
Durante M., Reppingen N., Held K.D. Immunologically augmented cancer treatment using modern radiotherapy. Trends Mol. Med 2013, 19:565-582.
-
(2013)
Trends Mol. Med
, vol.19
, pp. 565-582
-
-
Durante, M.1
Reppingen, N.2
Held, K.D.3
|