메뉴 건너뛰기




Volumn 109, Issue 6, 2015, Pages 1202-1213

Oligomerization of a Glucagon-like Peptide 1 Analog: Bridging Experiment and Simulations

Author keywords

[No Author keywords available]

Indexed keywords

LIRAGLUTIDE; SOLVENT; WATER;

EID: 84941805635     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2015.07.051     Document Type: Article
Times cited : (42)

References (50)
  • 1
    • 84883256420 scopus 로고    scopus 로고
    • Future directions for peptide therapeutics development
    • A.A. Kaspar, and J.M. Reichert Future directions for peptide therapeutics development Drug Discov. Today 18 2013 807 817
    • (2013) Drug Discov. Today , vol.18 , pp. 807-817
    • Kaspar, A.A.1    Reichert, J.M.2
  • 2
    • 84883564684 scopus 로고    scopus 로고
    • Self-assembling peptides improve the stability of glucagon-like peptide-1 by forming a stable and sustained complex
    • Y. Li, and M. Shao M. Gong Self-assembling peptides improve the stability of glucagon-like peptide-1 by forming a stable and sustained complex Mol. Pharm. 10 2013 3356 3365
    • (2013) Mol. Pharm. , vol.10 , pp. 3356-3365
    • Li, Y.1    Shao, M.2    Gong, M.3
  • 3
    • 0037181507 scopus 로고    scopus 로고
    • NMR studies of the aggregation of glucagon-like peptide-1: Formation of a symmetric helical dimer
    • X. Chang, and D. Keller J.J. Led NMR studies of the aggregation of glucagon-like peptide-1: formation of a symmetric helical dimer FEBS Lett. 515 2002 165 170
    • (2002) FEBS Lett. , vol.515 , pp. 165-170
    • Chang, X.1    Keller, D.2    Led, J.J.3
  • 4
    • 84862274737 scopus 로고    scopus 로고
    • Physiology and emerging biochemistry of the glucagon-like peptide-1 receptor
    • F.S. Willard, and K.W. Sloop Physiology and emerging biochemistry of the glucagon-like peptide-1 receptor Exp. Diabetes Res. 2012 2012 470851
    • (2012) Exp. Diabetes Res. , vol.2012 , pp. 470851
    • Willard, F.S.1    Sloop, K.W.2
  • 5
    • 84922129559 scopus 로고    scopus 로고
    • Liraglutide, a once-daily human GLP-1 analogue
    • M.A. Nauck Liraglutide, a once-daily human GLP-1 analogue Br. J. Diabetes Vasc. Dis. 8 2008 S26 S33
    • (2008) Br. J. Diabetes Vasc. Dis. , vol.8 , pp. S26-S33
    • Nauck, M.A.1
  • 6
    • 35448986920 scopus 로고    scopus 로고
    • Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1
    • H.-J. Jang, and Z. Kokrashvili J.M. Egan Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1 Proc. Natl. Acad. Sci. USA 104 2007 15069 15074
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 15069-15074
    • Jang, H.-J.1    Kokrashvili, Z.2    Egan, J.M.3
  • 7
    • 84862262750 scopus 로고    scopus 로고
    • Diet, friend or foe of enteroendocrine cells: How it interacts with enteroendocrine cells
    • S. Moran-Ramos, A.R. Tovar, and N. Torres Diet, friend or foe of enteroendocrine cells: how it interacts with enteroendocrine cells Adv. Nutr. Int. Rev. J. 3 2012 8 20
    • (2012) Adv. Nutr. Int. Rev. J. , vol.3 , pp. 8-20
    • Moran-Ramos, S.1    Tovar, A.R.2    Torres, N.3
  • 8
    • 84859136126 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 secretion by direct stimulation of L cells with luminal sugar vs non-nutritive sweetener
    • K. Sakurai, and E.Y. Lee T. Miki Glucagon-like peptide-1 secretion by direct stimulation of L cells with luminal sugar vs non-nutritive sweetener J. Diabetes Investig. 3 2012 156 163
    • (2012) J. Diabetes Investig. , vol.3 , pp. 156-163
    • Sakurai, K.1    Lee, E.Y.2    Miki, T.3
  • 9
    • 33847617011 scopus 로고    scopus 로고
    • Mechanisms of action of glucagon-like peptide 1 in the pancreas
    • M.E. Doyle, and J.M. Egan Mechanisms of action of glucagon-like peptide 1 in the pancreas Pharmacol. Ther. 113 2007 546 593
    • (2007) Pharmacol. Ther. , vol.113 , pp. 546-593
    • Doyle, M.E.1    Egan, J.M.2
  • 10
    • 84890547453 scopus 로고    scopus 로고
    • The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications
    • S. Madsbad The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications Diabetes Obes. Metab. 16 2014 9 21
    • (2014) Diabetes Obes. Metab. , vol.16 , pp. 9-21
    • Madsbad, S.1
  • 11
    • 84908377065 scopus 로고    scopus 로고
    • Neuroprotective and anti-apoptotic effects of liraglutide in the rat brain following focal cerebral ischemia
    • S. Briyal, S. Shah, and A. Gulati Neuroprotective and anti-apoptotic effects of liraglutide in the rat brain following focal cerebral ischemia Neuroscience 281C 2014 269 281
    • (2014) Neuroscience , vol.281 C , pp. 269-281
    • Briyal, S.1    Shah, S.2    Gulati, A.3
  • 12
    • 84897881837 scopus 로고    scopus 로고
    • The nature, significance, and glucagon-like peptide-1 analog treatment of brain insulin resistance in Alzheimer's disease
    • K. Talbot, and H.Y. Wang The nature, significance, and glucagon-like peptide-1 analog treatment of brain insulin resistance in Alzheimer's disease Alzheimers Dement. 10 Suppl 1 2014 S12 S25
    • (2014) Alzheimers Dement. , vol.10 , Issue.1 , pp. S12-S25
    • Talbot, K.1    Wang, H.Y.2
  • 13
    • 84870586474 scopus 로고    scopus 로고
    • Neuroprotective actions of glucagon-like peptide-1 in differentiated human neuroprogenitor cells
    • K. Velmurugan, and R. Bouchard S. Pugazhenthi Neuroprotective actions of glucagon-like peptide-1 in differentiated human neuroprogenitor cells J. Neurochem. 123 2012 919 931
    • (2012) J. Neurochem. , vol.123 , pp. 919-931
    • Velmurugan, K.1    Bouchard, R.2    Pugazhenthi, S.3
  • 14
    • 84928017886 scopus 로고    scopus 로고
    • Protective effect of rhGLP-1 (7-36) on brain ischemia/reperfusion damage in diabetic rats
    • L. Zhao, and J. Xu Y. Fang Protective effect of rhGLP-1 (7-36) on brain ischemia/reperfusion damage in diabetic rats Brain Res. 1602 2015 153 159
    • (2015) Brain Res. , vol.1602 , pp. 153-159
    • Zhao, L.1    Xu, J.2    Fang, Y.3
  • 15
    • 84886592674 scopus 로고    scopus 로고
    • Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease
    • P.L. McClean, and C. Hölscher Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease Neuropharmacology 76 Pt A 2014 57 67
    • (2014) Neuropharmacology , vol.76 , pp. 57-67
    • McClean, P.L.1    Hölscher, C.2
  • 16
    • 4344675057 scopus 로고    scopus 로고
    • Therapeutic strategies based on glucagon-like peptide 1
    • C.F. Deacon Therapeutic strategies based on glucagon-like peptide 1 Diabetes 53 2004 2181 2189
    • (2004) Diabetes , vol.53 , pp. 2181-2189
    • Deacon, C.F.1
  • 17
    • 84903727223 scopus 로고    scopus 로고
    • Incretins: Their physiology and application in the treatment of diabetes mellitus
    • H.M. Tasyurek, and H.A. Altunbas S. Sanlioglu Incretins: their physiology and application in the treatment of diabetes mellitus Diabetes Metab. Res. Rev. 30 2014 354 371
    • (2014) Diabetes Metab. Res. Rev. , vol.30 , pp. 354-371
    • Tasyurek, H.M.1    Altunbas, H.A.2    Sanlioglu, S.3
  • 18
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • D.J. Drucker, and M.A. Nauck The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes Lancet 368 2006 1696 1705
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 19
    • 0027157849 scopus 로고
    • Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable
    • C. Orskov, A. Wettergren, and J.J. Holst Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable Diabetes 42 1993 658 661
    • (1993) Diabetes , vol.42 , pp. 658-661
    • Orskov, C.1    Wettergren, A.2    Holst, J.J.3
  • 20
    • 84901593760 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: Differences and similarities
    • A. Lund, F.K. Knop, and T. Vilsbøll Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: differences and similarities Eur. J. Intern. Med. 25 2014 407 414
    • (2014) Eur. J. Intern. Med. , vol.25 , pp. 407-414
    • Lund, A.1    Knop, F.K.2    Vilsbøll, T.3
  • 21
    • 0033988408 scopus 로고    scopus 로고
    • GLP-1-analogues resistant to degradation by dipeptidyl-peptidase IV in vitro
    • B. Gallwitz, and T. Ropeter W.E. Schmidt GLP-1-analogues resistant to degradation by dipeptidyl-peptidase IV in vitro Regul. Pept. 86 2000 103 111
    • (2000) Regul. Pept. , vol.86 , pp. 103-111
    • Gallwitz, B.1    Ropeter, T.2    Schmidt, W.E.3
  • 22
    • 79952291919 scopus 로고    scopus 로고
    • GLP-1 for type 2 diabetes
    • B. Ahrén GLP-1 for type 2 diabetes Exp. Cell Res. 317 2011 1239 1245
    • (2011) Exp. Cell Res. , vol.317 , pp. 1239-1245
    • Ahrén, B.1
  • 23
    • 84929206792 scopus 로고    scopus 로고
    • Liraglutide and obesity: A review of the data so far
    • E.E. Ladenheim Liraglutide and obesity: a review of the data so far Drug Des. Devel. Ther. 9 2015 1867 1875
    • (2015) Drug Des. Devel. Ther. , vol.9 , pp. 1867-1875
    • Ladenheim, E.E.1
  • 24
    • 84858978818 scopus 로고    scopus 로고
    • Protein misfolded oligomers: Experimental approaches, mechanism of formation, and structure-toxicity relationships
    • F. Bemporad, and F. Chiti Protein misfolded oligomers: experimental approaches, mechanism of formation, and structure-toxicity relationships Chem. Biol. 19 2012 315 327
    • (2012) Chem. Biol. , vol.19 , pp. 315-327
    • Bemporad, F.1    Chiti, F.2
  • 25
    • 57649232757 scopus 로고    scopus 로고
    • Molecular, pharmacological and clinical aspects of liraglutide, a once-daily human GLP-1 analogue
    • D. Russell-Jones Molecular, pharmacological and clinical aspects of liraglutide, a once-daily human GLP-1 analogue Mol. Cell. Endocrinol. 297 2009 137 140
    • (2009) Mol. Cell. Endocrinol. , vol.297 , pp. 137-140
    • Russell-Jones, D.1
  • 26
    • 0034108646 scopus 로고    scopus 로고
    • Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
    • L.B. Knudsen, and P.F. Nielsen H. Agersø Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration J. Med. Chem. 43 2000 1664 1669
    • (2000) J. Med. Chem. , vol.43 , pp. 1664-1669
    • Knudsen, L.B.1    Nielsen, P.F.2    Agersø, H.3
  • 27
    • 84895164679 scopus 로고    scopus 로고
    • Molecular mechanisms underlying physiological and receptor pleiotropic effects mediated by GLP-1R activation
    • K. Pabreja, and M.A. Mohd S.G.B. Furness Molecular mechanisms underlying physiological and receptor pleiotropic effects mediated by GLP-1R activation Br. J. Pharmacol. 171 2014 1114 1128
    • (2014) Br. J. Pharmacol. , vol.171 , pp. 1114-1128
    • Pabreja, K.1    Mohd, M.A.2    Furness, S.G.B.3
  • 28
    • 57649231326 scopus 로고    scopus 로고
    • The molecular basis for the delayed absorption of the once-daily Human GLP-1 analogue, liraglutide
    • D.B. Steensgaard, and J.K. Thomsen L.B. Knudsen The molecular basis for the delayed absorption of the once-daily Human GLP-1 analogue, liraglutide Diabetes 57 Suppl 1 2008 A164
    • (2008) Diabetes , vol.57 , Issue.1 , pp. A164
    • Steensgaard, D.B.1    Thomsen, J.K.2    Knudsen, L.B.3
  • 29
    • 84922189568 scopus 로고    scopus 로고
    • Transformation of oligomers of lipidated peptide induced by change in pH
    • Y. Wang, and A. Lomakin G.B. Benedek Transformation of oligomers of lipidated peptide induced by change in pH Mol. Pharm. 12 2015 411 419
    • (2015) Mol. Pharm. , vol.12 , pp. 411-419
    • Wang, Y.1    Lomakin, A.2    Benedek, G.B.3
  • 30
    • 84907720838 scopus 로고    scopus 로고
    • Acylation of Glucagon-like peptide-2: Interaction with lipid membranes and in vitro intestinal permeability
    • S. Trier, and L. Linderoth U.L. Rahbek Acylation of Glucagon-like peptide-2: interaction with lipid membranes and in vitro intestinal permeability PLoS One 9 2014 e109939
    • (2014) PLoS One , vol.9 , pp. e109939
    • Trier, S.1    Linderoth, L.2    Rahbek, U.L.3
  • 31
    • 0008739778 scopus 로고    scopus 로고
    • Structure and folding of glucagon-like peptide-1-(7-36)-amide in aqueous trifluoroethanol studied by NMR spectroscopy
    • X. Chang, and D. Keller J.J. Led Structure and folding of glucagon-like peptide-1-(7-36)-amide in aqueous trifluoroethanol studied by NMR spectroscopy Magn. Reson. Chem. 39 2001 477 483
    • (2001) Magn. Reson. Chem. , vol.39 , pp. 477-483
    • Chang, X.1    Keller, D.2    Led, J.J.3
  • 32
    • 84941804032 scopus 로고    scopus 로고
    • RxList
    • Victoza. Accessed July 5, 2015.
    • RxList, The Internet Drug Index. 2015. Victoza. http://www.rxlist.com/victoza-drug.htm. Accessed July 5, 2015.
    • (2015) The Internet Drug Index
  • 33
    • 27144505097 scopus 로고    scopus 로고
    • Protein identification and analysis tools in the ExPASy server
    • Humana Press New York
    • E. Gasteiger, and C. Hoogland A. Bairoch Protein identification and analysis tools in the ExPASy server The Proteomics Protocols Handbook 2005 Humana Press New York 571 607
    • (2005) The Proteomics Protocols Handbook , pp. 571-607
    • Gasteiger, E.1    Hoogland, C.2    Bairoch, A.3
  • 34
    • 0043122944 scopus 로고    scopus 로고
    • ExPASy: The proteomics server for in-depth protein knowledge and analysis
    • E. Gasteiger, and A. Gattiker A. Bairoch ExPASy: the proteomics server for in-depth protein knowledge and analysis Nucleic Acids Res. 31 2003 3784 3788
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3784-3788
    • Gasteiger, E.1    Gattiker, A.2    Bairoch, A.3
  • 35
    • 84874739967 scopus 로고    scopus 로고
    • The yellow mini-hutch for SAXS experiments at MAX IV Laboratory
    • A. Labrador, and Y. Cerenius T. Plivelic The yellow mini-hutch for SAXS experiments at MAX IV Laboratory J. Phys. Conf. Ser. 425 2013 72019
    • (2013) J. Phys. Conf. Ser. , vol.425 , pp. 72019
    • Labrador, A.1    Cerenius, Y.2    Plivelic, T.3
  • 36
    • 0141484613 scopus 로고    scopus 로고
    • PRIMUS: A Windows PC-based system for small-angle scattering data analysis
    • P.V. Konarev, and V.V. Volkov D.I. Svergun PRIMUS: a Windows PC-based system for small-angle scattering data analysis J. Appl. Cryst. 36 2003 1277 1282
    • (2003) J. Appl. Cryst. , vol.36 , pp. 1277-1282
    • Konarev, P.V.1    Volkov, V.V.2    Svergun, D.I.3
  • 37
    • 84859782518 scopus 로고    scopus 로고
    • New developments in the ATSAS program package for small-angle scattering data analysis
    • M.V. Petoukhov, and D. Franke D.I. Svergun New developments in the ATSAS program package for small-angle scattering data analysis J. Appl. Cryst. 45 2012 342 350
    • (2012) J. Appl. Cryst. , vol.45 , pp. 342-350
    • Petoukhov, M.V.1    Franke, D.2    Svergun, D.I.3
  • 38
    • 0026244044 scopus 로고
    • GNOM. A program package for small-angle scattering data processing
    • A.V. Semenyuk, and D.I. Svergun GNOM. A program package for small-angle scattering data processing J. Appl. Cryst. 24 1991 537 540
    • (1991) J. Appl. Cryst. , vol.24 , pp. 537-540
    • Semenyuk, A.V.1    Svergun, D.I.2
  • 39
    • 0017751668 scopus 로고
    • The Protein Data Bank. A computer-based archival file for macromolecular structures
    • F.C. Bernstein, and T.F. Koetzle M. Tasumi The Protein Data Bank. A computer-based archival file for macromolecular structures Eur. J. Biochem. 80 1977 319 324
    • (1977) Eur. J. Biochem. , vol.80 , pp. 319-324
    • Bernstein, F.C.1    Koetzle, T.F.2    Tasumi, M.3
  • 41
    • 0004016501 scopus 로고
    • Comparison of simple potential functions for simulating liquid water
    • W.L. Jorgensen, and J. Chandrasekhar M.L. Klein Comparison of simple potential functions for simulating liquid water J. Chem. Phys. 79 1983 926
    • (1983) J. Chem. Phys. , vol.79 , pp. 926
    • Jorgensen, W.L.1    Chandrasekhar, J.2    Klein, M.L.3
  • 43
    • 0041784950 scopus 로고    scopus 로고
    • All-atom empirical potential for molecular modeling and dynamics studies of proteins
    • A.D. MacKerell, and D. Bashford M. Karplus All-atom empirical potential for molecular modeling and dynamics studies of proteins J. Phys. Chem. B 102 1998 3586 3616
    • (1998) J. Phys. Chem. B , vol.102 , pp. 3586-3616
    • MacKerell, A.D.1    Bashford, D.2    Karplus, M.3
  • 44
    • 79957583778 scopus 로고    scopus 로고
    • Secretory phospholipase A2 activity toward diverse substrates
    • J.J. Madsen, and L. Linderoth G.H. Peters Secretory phospholipase A2 activity toward diverse substrates J. Phys. Chem. B 115 2011 6853 6861
    • (2011) J. Phys. Chem. B , vol.115 , pp. 6853-6861
    • Madsen, J.J.1    Linderoth, L.2    Peters, G.H.3
  • 46
    • 0029185933 scopus 로고
    • CRYSOL - A program to evaluate x-ray solution scattering of biological macromolecules from atomic coordinates
    • D. Svergun, C. Barberato, and M.H. Koch CRYSOL - a program to evaluate x-ray solution scattering of biological macromolecules from atomic coordinates J. Appl. Cryst. 28 1995 768 773
    • (1995) J. Appl. Cryst. , vol.28 , pp. 768-773
    • Svergun, D.1    Barberato, C.2    Koch, M.H.3
  • 47
    • 34248397195 scopus 로고    scopus 로고
    • Accuracy of molecular mass determination of proteins in solution by small-angle x-ray scattering
    • E. Mylonas, and D.I. Svergun Accuracy of molecular mass determination of proteins in solution by small-angle x-ray scattering J. Appl. Cryst. 40 2007 s245 s249
    • (2007) J. Appl. Cryst. , vol.40 , pp. s245-s249
    • Mylonas, E.1    Svergun, D.I.2
  • 48
    • 33846823909 scopus 로고
    • Particle mesh Ewald: An N log(N) method for Ewald sums in large systems
    • T. Darden, D. York, and L. Pedersen Particle mesh Ewald: an N log(N) method for Ewald sums in large systems J. Chem. Phys. 98 1993 10089 10092
    • (1993) J. Chem. Phys. , vol.98 , pp. 10089-10092
    • Darden, T.1    York, D.2    Pedersen, L.3
  • 50
    • 36449007836 scopus 로고
    • Constant-pressure molecular-dynamics simulation - The Langevin piston method
    • S.E. Feller, and Y. Zhang B.R. Brooks Constant-pressure molecular-dynamics simulation - the Langevin piston method J. Chem. Phys. 103 1995 4613 4621
    • (1995) J. Chem. Phys. , vol.103 , pp. 4613-4621
    • Feller, S.E.1    Zhang, Y.2    Brooks, B.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.