메뉴 건너뛰기




Volumn 123, Issue 6, 2012, Pages 919-931

Neuroprotective actions of Glucagon-like peptide-1 in differentiated human neuroprogenitor cells

Author keywords

Alzheimer's disease; apoptosis; CREB; glucagon like peptide 1; human neuroprogenitor cells; signal transduction

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; CASPASE 6; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; NEUROTROPHIN; RETINOIC ACID;

EID: 84870586474     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12036     Document Type: Article
Times cited : (34)

References (48)
  • 1
    • 69549138878 scopus 로고    scopus 로고
    • Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease
    • Abbas T., Faivre E., and, Holscher C., (2009) Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease. Behav. Brain Res. 205, 265-271.
    • (2009) Behav. Brain Res. , vol.205 , pp. 265-271
    • Abbas, T.1    Faivre, E.2    Holscher, C.3
  • 3
    • 73349116624 scopus 로고    scopus 로고
    • New therapeutic horizons: Mapping the future of glycemic control with incretin-based therapy
    • Campbell R. K., and, Miller S.,. (2009) New therapeutic horizons: mapping the future of glycemic control with incretin-based therapy. Diabetes Educ. 35, 731-747.
    • (2009) Diabetes Educ. , vol.35 , pp. 731-747
    • Campbell, R.K.1    Miller, S.2
  • 4
    • 77950476810 scopus 로고    scopus 로고
    • Conditional deletion of Stat3 promotes neurogenesis and inhibits astrogliogenesis in neural stem cells
    • Cao F., Hata R., Zhu P., Nakashiro K., and, Sakanaka M., (2010) Conditional deletion of Stat3 promotes neurogenesis and inhibits astrogliogenesis in neural stem cells. Biochem. Biophys. Res. Commun. 394, 843-847.
    • (2010) Biochem. Biophys. Res. Commun. , vol.394 , pp. 843-847
    • Cao, F.1    Hata, R.2    Zhu, P.3    Nakashiro, K.4    Sakanaka, M.5
  • 5
    • 58149389397 scopus 로고    scopus 로고
    • HDAC4 regulates neuronal survival in normal and diseased retinas
    • Chen B., and, Cepko C. L., (2009) HDAC4 regulates neuronal survival in normal and diseased retinas. Science 323, 256-259.
    • (2009) Science , vol.323 , pp. 256-259
    • Chen, B.1    Cepko, C.L.2
  • 6
    • 84859360922 scopus 로고    scopus 로고
    • The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: A new role for mesolimbic GLP-1 receptors
    • Dickson S. L., Shirazi R. H., Hansson C., Bergquist F., Nissbrandt H., and, Skibicka K. P., (2012) The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1 receptors. J. Neurosci. 32, 4812-4820.
    • (2012) J. Neurosci. , vol.32 , pp. 4812-4820
    • Dickson, S.L.1    Shirazi, R.H.2    Hansson, C.3    Bergquist, F.4    Nissbrandt, H.5    Skibicka, K.P.6
  • 7
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • Drucker D. J., (2006) The biology of incretin hormones. Cell Metab. 3, 153-165.
    • (2006) Cell Metab. , vol.3 , pp. 153-165
    • Drucker, D.J.1
  • 8
    • 0028108923 scopus 로고
    • CREB: A mediator of long-term memory from mollusks to mammals
    • Frank D. A., and, Greenberg M. E., (1994) CREB: a mediator of long-term memory from mollusks to mammals. Cell 79, 5-8.
    • (1994) Cell , vol.79 , pp. 5-8
    • Frank, D.A.1    Greenberg, M.E.2
  • 9
    • 82755176046 scopus 로고    scopus 로고
    • Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice
    • Gengler S., McClean P. L., McCurtin R., Gault V. A., and, Holscher C., (2010) Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice. Neurobiol. Aging 265-276.
    • (2010) Neurobiol. Aging , pp. 265-276
    • Gengler, S.1    McClean, P.L.2    McCurtin, R.3    Gault, V.A.4    Holscher, C.5
  • 10
    • 0345305844 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons
    • Gilman C. P., Perry T., Furukawa K., Grieg N. H., Egan J. M., and, Mattson M. P., (2003) Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons. J. Neurochem. 87, 1137-1144.
    • (2003) J. Neurochem. , vol.87 , pp. 1137-1144
    • Gilman, C.P.1    Perry, T.2    Furukawa, K.3    Grieg, N.H.4    Egan, J.M.5    Mattson, M.P.6
  • 12
    • 79751479118 scopus 로고    scopus 로고
    • Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain
    • Hamilton A., Patterson S., Porter D., Gault V. A., and, Holscher C., (2011) Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain. J. Neurosci. Res. 89, 481-489.
    • (2011) J. Neurosci. Res. , vol.89 , pp. 481-489
    • Hamilton, A.1    Patterson, S.2    Porter, D.3    Gault, V.A.4    Holscher, C.5
  • 13
    • 77951058598 scopus 로고    scopus 로고
    • Linking type 2 diabetes and Alzheimer's disease
    • Han W., and, Li C., (2010) Linking type 2 diabetes and Alzheimer's disease. Proc. Natl Acad. Sci. USA 107, 6557-6558.
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 6557-6558
    • Han, W.1    Li, C.2
  • 14
    • 33749177143 scopus 로고    scopus 로고
    • A hundred years of Alzheimer's disease research
    • Hardy J., (2006) A hundred years of Alzheimer's disease research. Neuron 52, 3-13.
    • (2006) Neuron , vol.52 , pp. 3-13
    • Hardy, J.1
  • 15
    • 4644286910 scopus 로고    scopus 로고
    • Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease
    • Ho L., Qin W., Pompl P. N., et al,. (2004) Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease. FASEB J. 18, 902-904.
    • (2004) FASEB J. , vol.18 , pp. 902-904
    • Ho, L.1    Qin, W.2    Pompl, P.N.3
  • 16
    • 77954953382 scopus 로고    scopus 로고
    • New roles for insulin-like hormones in neuronal signalling and protection: New hopes for novel treatments of Alzheimer's disease?
    • Holscher C., and, Li L., (2010) New roles for insulin-like hormones in neuronal signalling and protection: new hopes for novel treatments of Alzheimer's disease? Neurobiol. Aging 31, 1495-1502.
    • (2010) Neurobiol. Aging , vol.31 , pp. 1495-1502
    • Holscher, C.1    Li, L.2
  • 18
    • 77955611520 scopus 로고    scopus 로고
    • Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: Diabetes, obesity, osteoporosis and Alzheimer's disease?
    • Irwin N., Gault V., and, Flatt P. R., (2010) Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: diabetes, obesity, osteoporosis and Alzheimer's disease? Expert Opin. Investig. Drugs 19, 1039-1048.
    • (2010) Expert Opin. Investig. Drugs , vol.19 , pp. 1039-1048
    • Irwin, N.1    Gault, V.2    Flatt, P.R.3
  • 21
    • 77953094551 scopus 로고    scopus 로고
    • Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells
    • Li Y., Tweedie D., Mattson M. P., Holloway H. W., and, Greig N. H., (2010) Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells. J. Neurochem. 113, 1621-1631.
    • (2010) J. Neurochem. , vol.113 , pp. 1621-1631
    • Li, Y.1    Tweedie, D.2    Mattson, M.P.3    Holloway, H.W.4    Greig, N.H.5
  • 22
    • 79955749452 scopus 로고    scopus 로고
    • The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease
    • McClean P. L., Parthsarathy V., Faivre E., and, Holscher C., (2011) The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease. J. Neurosci. 31, 6587-6594.
    • (2011) J. Neurosci. , vol.31 , pp. 6587-6594
    • McClean, P.L.1    Parthsarathy, V.2    Faivre, E.3    Holscher, C.4
  • 23
    • 57349190573 scopus 로고    scopus 로고
    • Regional and cellular distribution of ephrin-B1 in adult mouse brain
    • Migani P., Bartlett C., Dunlop S., Beazley L., and, Rodger J., (2009) Regional and cellular distribution of ephrin-B1 in adult mouse brain. Brain Res. 1247, 50-61.
    • (2009) Brain Res. , vol.1247 , pp. 50-61
    • Migani, P.1    Bartlett, C.2    Dunlop, S.3    Beazley, L.4    Rodger, J.5
  • 24
    • 0029966469 scopus 로고    scopus 로고
    • The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation
    • Nikolic M., Dudek H., Kwon Y. T., Ramos Y. F., and, Tsai L. H., (1996) The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev. 10, 816-825.
    • (1996) Genes Dev. , vol.10 , pp. 816-825
    • Nikolic, M.1    Dudek, H.2    Kwon, Y.T.3    Ramos, Y.F.4    Tsai, L.H.5
  • 25
    • 0032764016 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of dementia. The Rotterdam study
    • Ott A., Stolk R., Harskamp F. V., Pols H., Hoffman A., and, Breteler M., (1999) Diabetes mellitus and the risk of dementia. The Rotterdam study. Neurology 53, 1937-1942.
    • (1999) Neurology , vol.53 , pp. 1937-1942
    • Ott, A.1    Stolk, R.2    Harskamp, F.V.3    Pols, H.4    Hoffman, A.5    Breteler, M.6
  • 26
    • 79952442060 scopus 로고    scopus 로고
    • Neuroprotective therapeutics for Alzheimer's disease: Progress and prospects
    • Palmer A. M., (2011) Neuroprotective therapeutics for Alzheimer's disease: progress and prospects. Trends Pharmacol. Sci. 32, 141-147.
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 141-147
    • Palmer, A.M.1
  • 27
    • 0036966876 scopus 로고    scopus 로고
    • The glucagon-like peptides: A new genre in therapeutic targets for intervention in Alzheimer's disease
    • Perry T., and, Greig N. H., (2002) The glucagon-like peptides: a new genre in therapeutic targets for intervention in Alzheimer's disease. J. Alzheimers Dis. 4, 487-496.
    • (2002) J. Alzheimers Dis. , vol.4 , pp. 487-496
    • Perry, T.1    Greig, N.H.2
  • 28
    • 22144491473 scopus 로고    scopus 로고
    • Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease
    • Perry T., and, Greig N. H., (2005) Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease. Curr. Alzheimer Res. 2, 377-385.
    • (2005) Curr. Alzheimer Res. , vol.2 , pp. 377-385
    • Perry, T.1    Greig, N.H.2
  • 29
  • 30
    • 79952255488 scopus 로고    scopus 로고
    • Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene
    • Pruunsild P., Sepp M., Orav E., Koppel I., and, Timmusk T., (2011) Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene. J. Neurosci. 31, 3295-3308.
    • (2011) J. Neurosci. , vol.31 , pp. 3295-3308
    • Pruunsild, P.1    Sepp, M.2    Orav, E.3    Koppel, I.4    Timmusk, T.5
  • 31
    • 0033614021 scopus 로고    scopus 로고
    • Insulin-like growth factor I-mediated activation of the transcription factor cAMP response element-binding protein in PC12 cells. Involvement of p38 mitogen-activated protein kinase-mediated pathway
    • Pugazhenthi S., Boras T., O'Connor D., Meintzer M. K., Heidenreich K. A., and, Reusch J. E., (1999a) Insulin-like growth factor I-mediated activation of the transcription factor cAMP response element-binding protein in PC12 cells. Involvement of p38 mitogen-activated protein kinase-mediated pathway. J. Biol. Chem. 274, 2829-2837.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2829-2837
    • Pugazhenthi, S.1    Boras, T.2    O'Connor, D.3    Meintzer, M.K.4    Heidenreich, K.A.5    Reusch, J.E.6
  • 32
    • 0033600722 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element binding protein
    • Pugazhenthi S., Miller E., Sable C., Young P., Heidenreich K. A., Boxer L. M., and, Reusch J. E.-B., (1999b) Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element binding protein. J. Biol. Chem. 274, 27529-27535.
    • (1999) J. Biol. Chem. , vol.274 , pp. 27529-27535
    • Pugazhenthi, S.1    Miller, E.2    Sable, C.3    Young, P.4    Heidenreich, K.A.5    Boxer, L.M.6    Reusch, J.E.-B.7
  • 33
  • 36
    • 77957678974 scopus 로고    scopus 로고
    • Anti-inflammatory action of exendin-4 in human islets is enhanced by phosphodiesterase inhibitors: Potential therapeutic benefits in diabetic patients
    • Pugazhenthi U., Velmurugan K., Tran A., Mahaffey G., and, Pugazhenthi S., (2010) Anti-inflammatory action of exendin-4 in human islets is enhanced by phosphodiesterase inhibitors: potential therapeutic benefits in diabetic patients. Diabetologia 53, 2357-2368.
    • (2010) Diabetologia , vol.53 , pp. 2357-2368
    • Pugazhenthi, U.1    Velmurugan, K.2    Tran, A.3    Mahaffey, G.4    Pugazhenthi, S.5
  • 37
    • 80051791713 scopus 로고    scopus 로고
    • Downregulation of CREB expression in Alzheimer's brain and in Abeta-treated rat hippocampal neurons
    • Pugazhenthi S., Wang M., Pham S., Sze C. I., and, Eckman C. B., (2011a) Downregulation of CREB expression in Alzheimer's brain and in Abeta-treated rat hippocampal neurons. Mol. Neurodegener. 6, 60.
    • (2011) Mol. Neurodegener. , vol.6 , pp. 60
    • Pugazhenthi, S.1    Wang, M.2    Pham, S.3    Sze, C.I.4    Eckman, C.B.5
  • 41
    • 41149176407 scopus 로고    scopus 로고
    • Lack of pathology in a triple transgenic mouse model of Alzheimer's disease after overexpression of the anti-apoptotic protein Bcl-2
    • Rohn T. T., Vyas V., Hernandez-Estrada T., Nichol K. E., Christie L. A., and, Head E., (2008) Lack of pathology in a triple transgenic mouse model of Alzheimer's disease after overexpression of the anti-apoptotic protein Bcl-2. J. Neurosci. 28, 3051-3059.
    • (2008) J. Neurosci. , vol.28 , pp. 3051-3059
    • Rohn, T.T.1    Vyas, V.2    Hernandez-Estrada, T.3    Nichol, K.E.4    Christie, L.A.5    Head, E.6
  • 42
    • 0034830488 scopus 로고    scopus 로고
    • Caspases, apoptosis, and Alzheimer disease: Causation, correlation, and confusion
    • Roth K. A., (2001) Caspases, apoptosis, and Alzheimer disease: causation, correlation, and confusion. J. Neuropathol. Exp. Neurol. 60, 829-838.
    • (2001) J. Neuropathol. Exp. Neurol. , vol.60 , pp. 829-838
    • Roth, K.A.1
  • 43
    • 77954215576 scopus 로고    scopus 로고
    • An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies
    • Ryan D. A., Narrow W. C., Federoff H. J., and, Bowers W. J., (2010) An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies. J. Neurosci. Methods 190, 171-179.
    • (2010) J. Neurosci. Methods , vol.190 , pp. 171-179
    • Ryan, D.A.1    Narrow, W.C.2    Federoff, H.J.3    Bowers, W.J.4
  • 44
    • 34447128330 scopus 로고    scopus 로고
    • Dominant negative mutant forms of the cAMP response element binding protein induce apoptosis and decrease the anti-apoptotic action of growth factors in human islets
    • Sarkar S. A., Gunter J., Bouchard R., Reusch J. E., Wiseman A., Gill R. G., Hutton J. C., and, Pugazhenthi S., (2007) Dominant negative mutant forms of the cAMP response element binding protein induce apoptosis and decrease the anti-apoptotic action of growth factors in human islets. Diabetologia 50, 1649-1659.
    • (2007) Diabetologia , vol.50 , pp. 1649-1659
    • Sarkar, S.A.1    Gunter, J.2    Bouchard, R.3    Reusch, J.E.4    Wiseman, A.5    Gill, R.G.6    Hutton, J.C.7    Pugazhenthi, S.8
  • 46
    • 70449732132 scopus 로고    scopus 로고
    • Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus
    • Valente T., Gella A., Fernandez-Busquets X., Unzeta M., and, Durany N., (2010) Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus. Neurobiol. Dis. 37, 67-76.
    • (2010) Neurobiol. Dis. , vol.37 , pp. 67-76
    • Valente, T.1    Gella, A.2    Fernandez-Busquets, X.3    Unzeta, M.4    Durany, N.5
  • 48
    • 0033541589 scopus 로고    scopus 로고
    • Impaired phosphrylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimers type
    • Yamamoto-sasaki M., Ozawa H., Saito T., Rosler M., and, Riederer P., (1999) Impaired phosphrylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimers type. Brain Res. 824, 300-303.
    • (1999) Brain Res. , vol.824 , pp. 300-303
    • Yamamoto-Sasaki, M.1    Ozawa, H.2    Saito, T.3    Rosler, M.4    Riederer, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.