-
1
-
-
33847250395
-
Mouse and rat BDNF gene structure and expression revisited
-
Aid T., Kazantseva A., Piirsoo M., Palm K., and, Timmusk T., (2007) Mouse and rat BDNF gene structure and expression revisited. J. Neurosci. Res. 85, 525-535.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 525-535
-
-
Aid, T.1
Kazantseva, A.2
Piirsoo, M.3
Palm, K.4
Timmusk, T.5
-
2
-
-
46149100739
-
Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons
-
An J. J., Gharami K., Liao G.-Y., et al., (2008) Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell 134, 175-187.
-
(2008)
Cell
, vol.134
, pp. 175-187
-
-
An, J.J.1
Gharami, K.2
Liao, G.-Y.3
-
3
-
-
80053640722
-
Spatial segregation of BDNF transcripts enables BDNF to differentially shape distinct dendritic compartments
-
Baj G., Leone E., Chao M. V., and, Tongiorgi E., (2011) Spatial segregation of BDNF transcripts enables BDNF to differentially shape distinct dendritic compartments. Proc. Natl Acad. Sci. USA 108, 16813-16818.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 16813-16818
-
-
Baj, G.1
Leone, E.2
Chao, M.V.3
Tongiorgi, E.4
-
4
-
-
0033635904
-
Neurotrophins: Key regulators of cell fate and cell shape in the vertebrate nervous system
-
Bibel M., and, Barde Y. A., (2000) Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev. 14, 2919-2937.
-
(2000)
Genes Dev.
, vol.14
, pp. 2919-2937
-
-
Bibel, M.1
Barde, Y.A.2
-
5
-
-
5744233877
-
Brain-derived neurotrophic factor
-
Binder D. K., and, Scharfman H. E., (2004) Brain-derived neurotrophic factor. Growth Factors 22, 123-131.
-
(2004)
Growth Factors
, vol.22
, pp. 123-131
-
-
Binder, D.K.1
Scharfman, H.E.2
-
7
-
-
0030696750
-
Neurotrophin release by neurotrophins: Implications for activity-dependent neuronal plasticity
-
Canossa M., Griesbeck O., Berninger B., Campana G., Kolbeck R., and, Thoenen H., (1997) Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity. Proc. Natl Acad. Sci. USA 94, 13279-13286.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 13279-13286
-
-
Canossa, M.1
Griesbeck, O.2
Berninger, B.3
Campana, G.4
Kolbeck, R.5
Thoenen, H.6
-
8
-
-
21544461501
-
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway
-
Chen Z.-Y., Ieraci A., Teng H., Dall H., Meng C.-X., Herrera D. G., Nykjaer A., Hempstead B. L., and, Lee F. S., (2005) Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. J. Neurosci. 25, 6156-6166.
-
(2005)
J. Neurosci.
, vol.25
, pp. 6156-6166
-
-
Chen, Z.-Y.1
Ieraci, A.2
Teng, H.3
Dall, H.4
Meng, C.-X.5
Herrera, D.G.6
Nykjaer, A.7
Hempstead, B.L.8
Lee, F.S.9
-
9
-
-
70349482565
-
Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation
-
Chiaruttini C., Vicario A., Li Z., Baj G., Braiuca P., Wu Y., Lee F. S., Gardossi L., Baraban J. M., and, Tongiorgi E., (2009) Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation. Proc. Natl Acad. Sci. USA 106, 16481-16486.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 16481-16486
-
-
Chiaruttini, C.1
Vicario, A.2
Li, Z.3
Baj, G.4
Braiuca, P.5
Wu, Y.6
Lee, F.S.7
Gardossi, L.8
Baraban, J.M.9
Tongiorgi, E.10
-
10
-
-
0037462449
-
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
-
Egan M. F., Kojima M., Callicott J. H., et al., (2003) The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112, 257-269.
-
(2003)
Cell
, vol.112
, pp. 257-269
-
-
Egan, M.F.1
Kojima, M.2
Callicott, J.H.3
-
11
-
-
33847787591
-
Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and v in differentiated human neuroblastoma cells
-
Garzon D. J., and, Fahnestock M., (2007) Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells. J. Neurosci. 27, 2628-2635.
-
(2007)
J. Neurosci.
, vol.27
, pp. 2628-2635
-
-
Garzon, D.J.1
Fahnestock, M.2
-
12
-
-
0029939502
-
Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons
-
Goodman L. J., Valverde J., Lim F., Geschwind M. D., Federoff H. J., Geller A. I., and, Hefti F., (1996) Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons. Mol. Cell Neurosci. 7, 222-238.
-
(1996)
Mol. Cell Neurosci.
, vol.7
, pp. 222-238
-
-
Goodman, L.J.1
Valverde, J.2
Lim, F.3
Geschwind, M.D.4
Federoff, H.J.5
Geller, A.I.6
Hefti, F.7
-
13
-
-
33748937555
-
The surprising complexity of signal sequences
-
Hegde R. S., and, Bernstein H. D., (2006) The surprising complexity of signal sequences. Trends Biochem. Sci. 31, 563-571.
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 563-571
-
-
Hegde, R.S.1
Bernstein, H.D.2
-
14
-
-
0029845927
-
The regulated secretion and vectorial targeting of neurotrophins in neuroendocrine and epithelial cells
-
Heymach J. V., Krüttgen A., Suter U., and, Shooter E. M., (1996) The regulated secretion and vectorial targeting of neurotrophins in neuroendocrine and epithelial cells. J. Biol. Chem. 271, 25430-25437.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25430-25437
-
-
Heymach, J.V.1
Krüttgen, A.2
Suter, U.3
Shooter, E.M.4
-
15
-
-
65249155356
-
Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution
-
Jiang X., Zhou J., Mash D. C., Marini A. M., and, Lipsky R. H., (2009) Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution. Neuromolecular Med. 11, 1-12.
-
(2009)
Neuromolecular Med.
, vol.11
, pp. 1-12
-
-
Jiang, X.1
Zhou, J.2
Mash, D.C.3
Marini, A.M.4
Lipsky, R.H.5
-
16
-
-
13444292151
-
AAV-mediated hippocampal expression of short and long Homer 1 proteins differentially affect cognition and seizure activity in adult rats
-
Klugmann M., Symes C. W., Leichtlein C. B., Klaussner B. K., Dunning J., Fong D., Young D., and, During M. J., (2005) AAV-mediated hippocampal expression of short and long Homer 1 proteins differentially affect cognition and seizure activity in adult rats. Mol. Cell Neurosci. 28, 347-360.
-
(2005)
Mol. Cell Neurosci.
, vol.28
, pp. 347-360
-
-
Klugmann, M.1
Symes, C.W.2
Leichtlein, C.B.3
Klaussner, B.K.4
Dunning, J.5
Fong, D.6
Young, D.7
During, M.J.8
-
17
-
-
84883020198
-
Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors
-
Koppel I., and, Timmusk T., (2013) Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors. Neuropharmacology 75C, 106-115.
-
(2013)
Neuropharmacology
, vol.75 C
, pp. 106-115
-
-
Koppel, I.1
Timmusk, T.2
-
18
-
-
0022552131
-
Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
-
Kozak M., (1986) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44, 283-292.
-
(1986)
Cell
, vol.44
, pp. 283-292
-
-
Kozak, M.1
-
19
-
-
0035976524
-
Regulation of cell survival by secreted proneurotrophins
-
Lee R., Kermani P., Teng K. K., and, Hempstead B. L., (2001) Regulation of cell survival by secreted proneurotrophins. Science 294, 1945-1948.
-
(2001)
Science
, vol.294
, pp. 1945-1948
-
-
Lee, R.1
Kermani, P.2
Teng, K.K.3
Hempstead, B.L.4
-
20
-
-
67650450676
-
Mechanisms, locations, and kinetics of synaptic BDNF secretion: An update
-
Lessmann V., and, Brigadski T., (2009) Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update. Neurosci. Res. 65, 11-22.
-
(2009)
Neurosci. Res.
, vol.65
, pp. 11-22
-
-
Lessmann, V.1
Brigadski, T.2
-
21
-
-
0012315645
-
Neurotrophin secretion: Current facts and future prospects
-
Lessmann V., Gottmann K., and, Malcangio M., (2003) Neurotrophin secretion: current facts and future prospects. Prog. Neurobiol. 69, 341-374.
-
(2003)
Prog. Neurobiol.
, vol.69
, pp. 341-374
-
-
Lessmann, V.1
Gottmann, K.2
Malcangio, M.3
-
22
-
-
38649128208
-
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF
-
Matsumoto T., Rauskolb S., Polack M., Klose J., Kolbeck R., Korte M., and, Barde Y.-A., (2008) Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat. Neurosci. 11, 131-133.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 131-133
-
-
Matsumoto, T.1
Rauskolb, S.2
Polack, M.3
Klose, J.4
Kolbeck, R.5
Korte, M.6
Barde, Y.-A.7
-
23
-
-
0027359034
-
Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation
-
Metsis M., Timmusk T., Arenas E., and, Persson H., (1993) Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation. Proc. Natl Acad. Sci. USA 90, 8802-8806.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 8802-8806
-
-
Metsis, M.1
Timmusk, T.2
Arenas, E.3
Persson, H.4
-
24
-
-
84862728161
-
Vertebrate protein glycosylation: Diversity, synthesis and function
-
Moremen K. W., Tiemeyer M., and, Nairn A. V., (2012) Vertebrate protein glycosylation: diversity, synthesis and function. Nat. Rev. Mol. Cell Biol. 13, 448-462.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 448-462
-
-
Moremen, K.W.1
Tiemeyer, M.2
Nairn, A.V.3
-
25
-
-
0033559386
-
Differential sorting of nerve growth factor and brain-derived neurotrophic factor in hippocampal neurons
-
Mowla S. J., Pareek S., Farhadi H. F., Petrecca K., Fawcett J. P., Seidah N. G., Morris S. J., Sossin W. S., and, Murphy R. A., (1999) Differential sorting of nerve growth factor and brain-derived neurotrophic factor in hippocampal neurons. J. Neurosci. 19, 2069-2080.
-
(1999)
J. Neurosci.
, vol.19
, pp. 2069-2080
-
-
Mowla, S.J.1
Pareek, S.2
Farhadi, H.F.3
Petrecca, K.4
Fawcett, J.P.5
Seidah, N.G.6
Morris, S.J.7
Sossin, W.S.8
Murphy, R.A.9
-
26
-
-
0035918236
-
Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor
-
Mowla S. J., Farhadi H. F., Pareek S., Atwal J. K., Morris S. J., Seidah N. G., and, Murphy R. A., (2001) Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor. J. Biol. Chem. 276, 12660-12666.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12660-12666
-
-
Mowla, S.J.1
Farhadi, H.F.2
Pareek, S.3
Atwal, J.K.4
Morris, S.J.5
Seidah, N.G.6
Murphy, R.A.7
-
27
-
-
5644251587
-
Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity
-
Pang P. T., Teng H. K., Zaitsev E., Woo N. T., Sakata K., Zhen S., Teng K. K., Yung W.-H., Hempstead B. L., and, Lu B., (2004) Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science 306, 487-491.
-
(2004)
Science
, vol.306
, pp. 487-491
-
-
Pang, P.T.1
Teng, H.K.2
Zaitsev, E.3
Woo, N.T.4
Sakata, K.5
Zhen, S.6
Teng, K.K.7
Yung, W.-H.8
Hempstead, B.L.9
Lu, B.10
-
28
-
-
34547499702
-
Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters
-
Pruunsild P., Kazantseva A., Aid T., Palm K., and, Timmusk T., (2007) Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics 90, 397-406.
-
(2007)
Genomics
, vol.90
, pp. 397-406
-
-
Pruunsild, P.1
Kazantseva, A.2
Aid, T.3
Palm, K.4
Timmusk, T.5
-
29
-
-
79952255488
-
Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene
-
Pruunsild P., Sepp M., Orav E., Koppel I., and, Timmusk T., (2011) Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene. J. Neurosci. 31, 3295-3308.
-
(2011)
J. Neurosci.
, vol.31
, pp. 3295-3308
-
-
Pruunsild, P.1
Sepp, M.2
Orav, E.3
Koppel, I.4
Timmusk, T.5
-
30
-
-
0030660436
-
Eukaryotic protein secretion
-
Sakaguchi M., (1997) Eukaryotic protein secretion. Curr. Opin. Biotechnol. 8, 595-601.
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 595-601
-
-
Sakaguchi, M.1
-
31
-
-
0030050741
-
Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases
-
Seidah N. G., Benjannet S., Pareek S., Chrétien M., and, Murphy R. A., (1996) Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases. FEBS Lett. 379, 247-250.
-
(1996)
FEBS Lett.
, vol.379
, pp. 247-250
-
-
Seidah, N.G.1
Benjannet, S.2
Pareek, S.3
Chrétien, M.4
Murphy, R.A.5
-
32
-
-
0037183985
-
Involvement of an upstream stimulatory factor as well as cAMP-responsive element-binding protein in the activation of brain-derived neurotrophic factor gene promoter i
-
Tabuchi A., Sakaya H., Kisukeda T., Fushiki H., and, Tsuda M., (2002) Involvement of an upstream stimulatory factor as well as cAMP-responsive element-binding protein in the activation of brain-derived neurotrophic factor gene promoter I. J. Biol. Chem. 277, 35920-35931.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 35920-35931
-
-
Tabuchi, A.1
Sakaya, H.2
Kisukeda, T.3
Fushiki, H.4
Tsuda, M.5
-
33
-
-
65549095426
-
Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1
-
Tian F., Hu X.-Z., Wu X., Jiang H., Pan H., Marini A. M., and, Lipsky R. H., (2009) Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1. J. Neurochem. 109, 1375-1388.
-
(2009)
J. Neurochem.
, vol.109
, pp. 1375-1388
-
-
Tian, F.1
Hu, X.-Z.2
Wu, X.3
Jiang, H.4
Pan, H.5
Marini, A.M.6
Lipsky, R.H.7
-
34
-
-
0027402152
-
Multiple promoters direct tissue-specific expression of the rat BDNF gene
-
Timmusk T., Palm K., Metsis M., Reintam T., Paalme V., Saarma M., and, Persson H., (1993) Multiple promoters direct tissue-specific expression of the rat BDNF gene. Neuron 10, 475-489.
-
(1993)
Neuron
, vol.10
, pp. 475-489
-
-
Timmusk, T.1
Palm, K.2
Metsis, M.3
Reintam, T.4
Paalme, V.5
Saarma, M.6
Persson, H.7
-
35
-
-
84907495393
-
Pharmacological profile of brain-derived neurotrophic factor (BDNF) splice variant translation using a novel drug screening assay: A "quantitative code"
-
Vaghi V., Polacchini A., Baj G., Pinheiro V. L. M., Vicario A., and, Tongiorgi E., (2014) Pharmacological profile of brain-derived neurotrophic factor (BDNF) splice variant translation using a novel drug screening assay: a "quantitative code". J. Biol. Chem. 289, 27702-27713.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 27702-27713
-
-
Vaghi, V.1
Polacchini, A.2
Baj, G.3
Pinheiro, V.L.M.4
Vicario, A.5
Tongiorgi, E.6
-
36
-
-
84903128632
-
Neurotrophins: Transcription and translation
-
West A. E., Pruunsild P., and, Timmusk T., (2014) Neurotrophins: transcription and translation. Handb. Exp. Pharmacol. 220, 67-100.
-
(2014)
Handb. Exp. Pharmacol.
, vol.220
, pp. 67-100
-
-
West, A.E.1
Pruunsild, P.2
Timmusk, T.3
-
37
-
-
84886441051
-
Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice
-
Wetsel W. C., Rodriguiz R. M., Guillemot J., et al., (2013) Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice. Proc. Natl Acad. Sci. 110, 17362-17367.
-
(2013)
Proc. Natl Acad. Sci.
, vol.110
, pp. 17362-17367
-
-
Wetsel, W.C.1
Rodriguiz, R.M.2
Guillemot, J.3
-
38
-
-
58849092865
-
Neuronal release of proBDNF
-
Yang J., Siao C.-J., Nagappan G., et al., (2009) Neuronal release of proBDNF. Nat. Neurosci. 12, 113-115.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 113-115
-
-
Yang, J.1
Siao, C.-J.2
Nagappan, G.3
-
39
-
-
33846847943
-
Decoding NMDA receptor signaling: Identification of genomic programs specifying neuronal survival and death
-
Zhang S.-J., Steijaert M. N., Lau D., Schütz G., Delucinge-Vivier C., Descombes P., and, Bading H., (2007) Decoding NMDA receptor signaling: identification of genomic programs specifying neuronal survival and death. Neuron 53, 549-562.
-
(2007)
Neuron
, vol.53
, pp. 549-562
-
-
Zhang, S.-J.1
Steijaert, M.N.2
Lau, D.3
Schütz, G.4
Delucinge-Vivier, C.5
Descombes, P.6
Bading, H.7
|