Epstein-Barr virus LMP2A reduces hyperactivation induced by LMP1 to restore normal B cell phenotype in transgenic mice

PLoS Pathogens

Volumn 8, Issue 4, 2012, Pages

  Vrazo, Alexandra C ^a   Chauchard, Maria ^a   Raab Traub, Nancy ^b   Longnecker, Richard ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LATENT MEMBRANE PROTEIN 1; LATENT MEMBRANE PROTEIN 2A; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG; VIRUS PROTEIN; EBV ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN BARR VIRUS; EBV-ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN-BARR VIRUS; MATRIX PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL MATURATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPSTEIN BARR VIRUS; FLOW CYTOMETRY; IMMUNOBLOTTING; IN VITRO STUDY; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PHENOTYPE; PLASMA CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; GENE REARRANGEMENT; GENETICS; GERMINAL CENTER; IMMUNOLOGICAL MEMORY; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE; VIROLOGY; VIRUS CELL TRANSFORMATION; VIRUS LATENCY;

ANIMALIA; HUMAN HERPESVIRUS 4; MUS; MUS MUSCULUS;

ANIMALS; B-LYMPHOCYTES; CELL TRANSFORMATION, VIRAL; GERMINAL CENTER; HERPESVIRUS 4, HUMAN; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOLOGIC MEMORY; MICE; MICE, TRANSGENIC; PHENOTYPE; TNF RECEPTOR-ASSOCIATED FACTOR 2; VIRAL MATRIX PROTEINS; VIRUS LATENCY;

EID: 84861203600     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002662     Document Type: Article

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