Deficiency in aryl hydrocarbon receptor (AHR) expression throughout aging alters gene expression profiles in murine long-term hematopoietic stem cells

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Bennett, John A ^a   Singh, Kameshwar P ^a   Unnisa, Zeenath ^a   Welle, Stephen L ^a   Gasiewicz, Thomas A ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; PLATELET DERIVED GROWTH FACTOR D; SMOOTHENED PROTEIN; AHR PROTEIN, MOUSE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; TRANSCRIPTOME;

ADULT; AGING; ANIMAL CELL; ARTICLE; BINDING SITE; CELL ACTIVITY; CELL FUNCTION; CELL RENEWAL; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL; INTRACELLULAR SIGNALING; MOUSE; MYELOPROLIFERATIVE DISORDER; NONHUMAN; PATHOGENESIS; PDGF D GENE; PROTEIN DEPLETION; PROTEIN EXPRESSION; SMO GENE; UPREGULATION; WDFY1 GENE; ZBTB37 GENE; ZFP382 GENE; ANIMAL; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENE SILENCING; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHENOTYPE; REPRODUCIBILITY; SIGNAL TRANSDUCTION;

AGING; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CLUSTER ANALYSIS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GENE REGULATORY NETWORKS; HEMATOPOIETIC STEM CELLS; MICE; MICE, KNOCKOUT; PHENOTYPE; RECEPTORS, ARYL HYDROCARBON; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; TRANSCRIPTOME;

EID: 84941651158     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0133791     Document Type: Article

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