메뉴 건너뛰기




Volumn 27, Issue 10, 2015, Pages 579-587

Incorporating Genetic Biomarkers into Predictive Models of Normal Tissue Toxicity

Author keywords

GWAS; Normal tissue; Radiosensitivity; Radiotherapy; SNP

Indexed keywords

BIOLOGICAL MARKER; GENETIC MARKER;

EID: 84941315223     PISSN: 09366555     EISSN: 14332981     Source Type: Journal    
DOI: 10.1016/j.clon.2015.06.013     Document Type: Article
Times cited : (40)

References (85)
  • 1
    • 22444441668 scopus 로고    scopus 로고
    • Towards evidence-based guidelines for radiotherapy infrastructure and staffing needs in Europe: the ESTRO QUARTS project
    • Bentzen S.M., Heeren G., Cottier B., et al. Towards evidence-based guidelines for radiotherapy infrastructure and staffing needs in Europe: the ESTRO QUARTS project. Radiother Oncol 2005, 75(3):355-365.
    • (2005) Radiother Oncol , vol.75 , Issue.3 , pp. 355-365
    • Bentzen, S.M.1    Heeren, G.2    Cottier, B.3
  • 2
    • 84928696768 scopus 로고    scopus 로고
    • Trends in the lifetime risk of developing cancer in Great Britain: comparison of risk for those born from 1930 to 1960
    • Ahmad A.S., Ormiston-Smith N., Sasieni P.D. Trends in the lifetime risk of developing cancer in Great Britain: comparison of risk for those born from 1930 to 1960. Br J Cancer 2015 Mar 3, 112(5):943-947.
    • (2015) Br J Cancer , vol.112 , Issue.5 , pp. 943-947
    • Ahmad, A.S.1    Ormiston-Smith, N.2    Sasieni, P.D.3
  • 4
    • 84941321706 scopus 로고    scopus 로고
    • Cancer statistics report: incidence UK. [accessed 04.03.15].
    • Cancer Research UK. Cancer statistics report: incidence UK, 2014. Available at: [accessed 04.03.15]. http://publications.cancerresearchuk.org/downloads/Product/CS_REPORT_INCIDENCE.pdf.
    • (2014)
  • 5
    • 36849079824 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy: supportive data for prostate cancer
    • Cahlon O., Hunt M., Zelefsky M.J. Intensity-modulated radiation therapy: supportive data for prostate cancer. Semin Radiat Oncol 2008, 18(1):48-57.
    • (2008) Semin Radiat Oncol , vol.18 , Issue.1 , pp. 48-57
    • Cahlon, O.1    Hunt, M.2    Zelefsky, M.J.3
  • 6
    • 34548132406 scopus 로고    scopus 로고
    • Significant reduction of acute toxicity following pelvic irradiation with helical tomotherapy in patients with localized prostate cancer
    • Cozzarini C., Fiorino C., Di Muzio N., et al. Significant reduction of acute toxicity following pelvic irradiation with helical tomotherapy in patients with localized prostate cancer. Radiother Oncol 2007, 84(2):164-170.
    • (2007) Radiother Oncol , vol.84 , Issue.2 , pp. 164-170
    • Cozzarini, C.1    Fiorino, C.2    Di Muzio, N.3
  • 7
    • 84897400934 scopus 로고    scopus 로고
    • Escalated-dose versus control-dose conformal radiotherapy for prostate cancer: long-term results from the MRC RT01 randomised controlled trial
    • Dearnaley D.P., Jovic G., Syndikus I., et al. Escalated-dose versus control-dose conformal radiotherapy for prostate cancer: long-term results from the MRC RT01 randomised controlled trial. Lancet Oncol 2014, 15(4):464-473.
    • (2014) Lancet Oncol , vol.15 , Issue.4 , pp. 464-473
    • Dearnaley, D.P.1    Jovic, G.2    Syndikus, I.3
  • 8
    • 33847388792 scopus 로고    scopus 로고
    • Randomised trial of standard 2D radiotherapy (RT) versus intensity-modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy
    • Breast Technology Group
    • Donovan E., Bleakley N., Denholm E., et al. Randomised trial of standard 2D radiotherapy (RT) versus intensity-modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. Radiother Oncol 2007, 82(3):254-264. Breast Technology Group.
    • (2007) Radiother Oncol , vol.82 , Issue.3 , pp. 254-264
    • Donovan, E.1    Bleakley, N.2    Denholm, E.3
  • 9
    • 84894452493 scopus 로고    scopus 로고
    • Randomized controlled trial of intensity-modulated radiotherapy for early breast cancer: 5-year results confirm superior overall cosmesis
    • Mukesh M.B., Barnett G.C., Wilkinson J.S., et al. Randomized controlled trial of intensity-modulated radiotherapy for early breast cancer: 5-year results confirm superior overall cosmesis. J Clin Oncol 2013, 31(36):4488-4495.
    • (2013) J Clin Oncol , vol.31 , Issue.36 , pp. 4488-4495
    • Mukesh, M.B.1    Barnett, G.C.2    Wilkinson, J.S.3
  • 10
    • 79151484611 scopus 로고    scopus 로고
    • PARSPORT trial management group. Parotid-sparing intensity-modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial
    • Nutting C.M., Morden J.P., Harrington K.J., et al. PARSPORT trial management group. Parotid-sparing intensity-modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial. Lancet Oncol 2011, 12(2):127-136.
    • (2011) Lancet Oncol , vol.12 , Issue.2 , pp. 127-136
    • Nutting, C.M.1    Morden, J.P.2    Harrington, K.J.3
  • 11
    • 33750357039 scopus 로고    scopus 로고
    • Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a randomized controlled clinical trial
    • Pow E.H., Kwong D.L., McMillan A.S., et al. Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a randomized controlled clinical trial. Int J Radiat Oncol Biol Phys 2006, 66(4):981-991.
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , Issue.4 , pp. 981-991
    • Pow, E.H.1    Kwong, D.L.2    McMillan, A.S.3
  • 12
    • 40949149466 scopus 로고    scopus 로고
    • Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies
    • Veldeman L., Madani I., Hulstaert F., De Meerleer G., Mareel M., De Neve W. Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies. Lancet Oncol 2008, 9(4):367-375.
    • (2008) Lancet Oncol , vol.9 , Issue.4 , pp. 367-375
    • Veldeman, L.1    Madani, I.2    Hulstaert, F.3    De Meerleer, G.4    Mareel, M.5    De Neve, W.6
  • 13
    • 39749192109 scopus 로고    scopus 로고
    • Incidence of late rectal and urinary toxicities after three-dimensional conformal radiotherapy and intensity-modulated radiotherapy for localized prostate cancer
    • Zelefsky M.J., Levin E.J., Hunt M., et al. Incidence of late rectal and urinary toxicities after three-dimensional conformal radiotherapy and intensity-modulated radiotherapy for localized prostate cancer. Int J Radiat Oncol Biol Phys 2008, 70(4):1124-1129.
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , Issue.4 , pp. 1124-1129
    • Zelefsky, M.J.1    Levin, E.J.2    Hunt, M.3
  • 14
    • 84941321707 scopus 로고    scopus 로고
    • [accessed 03.06.15].
    • Cancer Research UK Research Strategy 2014. Available at: [accessed 03.06.15]. http://www.cancerresearchuk.org/sites/default/files/cruk_strategy.pdf.
    • (2014)
  • 15
    • 0001515617 scopus 로고
    • Erfahrungen über die Verträglichkeitsgrenze für Röntgenstrahlen und deren Nutzanwendung zur Verhütung von Schäden
    • Holthusen H. Erfahrungen über die Verträglichkeitsgrenze für Röntgenstrahlen und deren Nutzanwendung zur Verhütung von Schäden. Strahlentherapie 1936, 57:254-269.
    • (1936) Strahlentherapie , vol.57 , pp. 254-269
    • Holthusen, H.1
  • 16
    • 0016786321 scopus 로고
    • Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity
    • Taylor A.M., Harnden D.G., Arlett C.F., et al. Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity. Nature 1975, 258:427-429.
    • (1975) Nature , vol.258 , pp. 427-429
    • Taylor, A.M.1    Harnden, D.G.2    Arlett, C.F.3
  • 17
    • 0018837288 scopus 로고
    • Survey of radiosensitivity in a variety of human cell strains
    • Arlett C.F., Harcourt S.A. Survey of radiosensitivity in a variety of human cell strains. Cancer Res 1980, 40(3):926-932.
    • (1980) Cancer Res , vol.40 , Issue.3 , pp. 926-932
    • Arlett, C.F.1    Harcourt, S.A.2
  • 18
    • 0025381093 scopus 로고
    • In vitro radiosensitivity of human diploid fibroblasts derived from women with unusually sensitive clinical responses to definitive radiation therapy for breast cancer
    • Loeffler J.S., Harris J.R., Dahlberg W.K., Little J.B. In vitro radiosensitivity of human diploid fibroblasts derived from women with unusually sensitive clinical responses to definitive radiation therapy for breast cancer. Radiat Res 1990, 121:227-231.
    • (1990) Radiat Res , vol.121 , pp. 227-231
    • Loeffler, J.S.1    Harris, J.R.2    Dahlberg, W.K.3    Little, J.B.4
  • 19
    • 0025071030 scopus 로고
    • An instance of clinical radiation morbidity and cellular radiosensitivity, not associated with ataxia-telangiectasia
    • Plowman P.N., Bridges B.A., Arlett C.F., Hinney A., Kingston J.E. An instance of clinical radiation morbidity and cellular radiosensitivity, not associated with ataxia-telangiectasia. Br J Radiol 1990, 63:624-628.
    • (1990) Br J Radiol , vol.63 , pp. 624-628
    • Plowman, P.N.1    Bridges, B.A.2    Arlett, C.F.3    Hinney, A.4    Kingston, J.E.5
  • 20
    • 0019208703 scopus 로고
    • Radiosensitivity in vitro of human fibroblasts derived from patients with a severe skin reaction to radiation therapy
    • Smith K.C., Hahn G.M., Hoppe R.T., Earle J.D. Radiosensitivity in vitro of human fibroblasts derived from patients with a severe skin reaction to radiation therapy. Int J Radiat Oncol Biol Phys 1980, 6:1573-1575.
    • (1980) Int J Radiat Oncol Biol Phys , vol.6 , pp. 1573-1575
    • Smith, K.C.1    Hahn, G.M.2    Hoppe, R.T.3    Earle, J.D.4
  • 21
    • 0023745128 scopus 로고
    • Sensitivity of cultured cells to gamma radiation in a patient exhibiting marked in vivo radiation sensitivity
    • Woods W.G., Byrne T.D., Kim T.H. Sensitivity of cultured cells to gamma radiation in a patient exhibiting marked in vivo radiation sensitivity. Cancer 1988, 62:2341-2345.
    • (1988) Cancer , vol.62 , pp. 2341-2345
    • Woods, W.G.1    Byrne, T.D.2    Kim, T.H.3
  • 22
    • 84960962997 scopus 로고
    • Action of x-rays on mammalian cells
    • Puck T.T., Marcus P.I. Action of x-rays on mammalian cells. J Exp Med 1956, 103:653-666.
    • (1956) J Exp Med , vol.103 , pp. 653-666
    • Puck, T.T.1    Marcus, P.I.2
  • 23
    • 0022502910 scopus 로고
    • Re-evaluation of in vitro radiosensitivity of human fibroblasts of different genetic origins
    • Erratum Int J Radiat Biol 1986;50(6):1129
    • Deschavanne P.J., Debieu D., Fertil B., Malaise E.P. Re-evaluation of in vitro radiosensitivity of human fibroblasts of different genetic origins. Int J Radiat Biol 1986, 50(2):279-293. Erratum Int J Radiat Biol 1986;50(6):1129.
    • (1986) Int J Radiat Biol , vol.50 , Issue.2 , pp. 279-293
    • Deschavanne, P.J.1    Debieu, D.2    Fertil, B.3    Malaise, E.P.4
  • 24
    • 0023744051 scopus 로고
    • Survival of human diploid skin fibroblasts from normal individuals after X-irradiation
    • Little J.B., Nove J., Strong L.C., Nichols W.W. Survival of human diploid skin fibroblasts from normal individuals after X-irradiation. Int J Radiat Biol 1988, 54:899-910.
    • (1988) Int J Radiat Biol , vol.54 , pp. 899-910
    • Little, J.B.1    Nove, J.2    Strong, L.C.3    Nichols, W.W.4
  • 25
    • 0023630928 scopus 로고
    • Initial slope of radiation survival curves is characteristic of the origin of primary and established cultures of human tumor cells and fibroblasts
    • Malaise E.P., Fertil B., Deschavanne P.J., Chavaudra N., Brock W.A. Initial slope of radiation survival curves is characteristic of the origin of primary and established cultures of human tumor cells and fibroblasts. Radiat Res 1987, 111:319-333.
    • (1987) Radiat Res , vol.111 , pp. 319-333
    • Malaise, E.P.1    Fertil, B.2    Deschavanne, P.J.3    Chavaudra, N.4    Brock, W.A.5
  • 26
    • 0026708350 scopus 로고
    • Improving radiotherapy cure rates by predicting normal tissue tolerance from in vitro cellular radiation sensitivity
    • Burnet N.G., Nyman J., Turesson I., Wurm R., Yarnold J.R., Peacock J.H. Improving radiotherapy cure rates by predicting normal tissue tolerance from in vitro cellular radiation sensitivity. Lancet 1992, 339:1570-1571.
    • (1992) Lancet , vol.339 , pp. 1570-1571
    • Burnet, N.G.1    Nyman, J.2    Turesson, I.3    Wurm, R.4    Yarnold, J.R.5    Peacock, J.H.6
  • 27
    • 0028584219 scopus 로고
    • The relationship between cellular radiation sensitivity and tissue response to radiotherapy may provide the basis for individualising radiotherapy schedules
    • Burnet N.G., Nyman J., Turesson I., Wurm R., Yarnold J.R., Peacock J.H. The relationship between cellular radiation sensitivity and tissue response to radiotherapy may provide the basis for individualising radiotherapy schedules. Radiother Oncol 1994, 33:228-238.
    • (1994) Radiother Oncol , vol.33 , pp. 228-238
    • Burnet, N.G.1    Nyman, J.2    Turesson, I.3    Wurm, R.4    Yarnold, J.R.5    Peacock, J.H.6
  • 28
    • 0027376513 scopus 로고
    • Prospective comparison of in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients
    • Geara F.B., Peters L.J., Ang K.K., Wike J.L., Brock W.A. Prospective comparison of in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients. Int J Radiat Oncol Biol 1993, 27:1173-1179.
    • (1993) Int J Radiat Oncol Biol , vol.27 , pp. 1173-1179
    • Geara, F.B.1    Peters, L.J.2    Ang, K.K.3    Wike, J.L.4    Brock, W.A.5
  • 29
    • 0027932166 scopus 로고
    • Evidence for a positive correlation between in vitro radiosensitivity of normal human skin fibroblasts and the occurrence of subcutaneous fibrosis after radiotherapy
    • Johansen J., Bentzen S.M., Overgaard J., Overgaard M. Evidence for a positive correlation between in vitro radiosensitivity of normal human skin fibroblasts and the occurrence of subcutaneous fibrosis after radiotherapy. Int J Radiat Oncol Biol Phys 1994, 66:407-412.
    • (1994) Int J Radiat Oncol Biol Phys , vol.66 , pp. 407-412
    • Johansen, J.1    Bentzen, S.M.2    Overgaard, J.3    Overgaard, M.4
  • 30
    • 0034194449 scopus 로고    scopus 로고
    • Cellular radiosensitivity and complication risk after curative radiotherapy
    • Peacock J., Ashton A., Bliss J., et al. Cellular radiosensitivity and complication risk after curative radiotherapy. Radiother Oncol 2000, 55(2):173-178.
    • (2000) Radiother Oncol , vol.55 , Issue.2 , pp. 173-178
    • Peacock, J.1    Ashton, A.2    Bliss, J.3
  • 31
    • 0035450979 scopus 로고    scopus 로고
    • Lymphocyte radiosensitivity is a significant prognostic factor for morbidity in carcinoma of the cervix
    • West C.M., Davidson S.E., Elyan S.A., et al. Lymphocyte radiosensitivity is a significant prognostic factor for morbidity in carcinoma of the cervix. Int J Radiat Oncol Biol Phys 2001, 51(1):10-15.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , Issue.1 , pp. 10-15
    • West, C.M.1    Davidson, S.E.2    Elyan, S.A.3
  • 33
    • 67651083729 scopus 로고    scopus 로고
    • Elevation of plasma TGF-beta1 during radiation therapy predicts radiation-induced lung toxicity in patients with non-small-cell lung cancer: a combined analysis from Beijing and Michigan
    • Zhao L., Wang L., Ji W., et al. Elevation of plasma TGF-beta1 during radiation therapy predicts radiation-induced lung toxicity in patients with non-small-cell lung cancer: a combined analysis from Beijing and Michigan. Int J Radiat Oncol Biol Phys 2009, 74(5):1385-1390.
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , Issue.5 , pp. 1385-1390
    • Zhao, L.1    Wang, L.2    Ji, W.3
  • 34
    • 0028168685 scopus 로고
    • Changes in plasma TGF beta levels during pulmonary radiotherapy as a predictor of the risk of developing radiation pneumonitis
    • Anscher M.S., Murase T., Prescott D.M., et al. Changes in plasma TGF beta levels during pulmonary radiotherapy as a predictor of the risk of developing radiation pneumonitis. Int J Radiat Oncol Biol Phys 1994, 30(3):671-676.
    • (1994) Int J Radiat Oncol Biol Phys , vol.30 , Issue.3 , pp. 671-676
    • Anscher, M.S.1    Murase, T.2    Prescott, D.M.3
  • 35
    • 0035879570 scopus 로고    scopus 로고
    • Predicting the risk of symptomatic radiation-induced lung injury using both the physical and biologic parameters V(30) and transforming growth factor beta
    • Fu X.L., Huang H., Bentel G., et al. Predicting the risk of symptomatic radiation-induced lung injury using both the physical and biologic parameters V(30) and transforming growth factor beta. Int J Radiat Oncol Biol Phys 2001, 50(4):899-908.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , Issue.4 , pp. 899-908
    • Fu, X.L.1    Huang, H.2    Bentel, G.3
  • 38
    • 0034109911 scopus 로고    scopus 로고
    • Comparison of DNA repair protein expression and activities between human fibroblast cell lines with different radiosensitivities
    • Carlomagno F., Burnet N.G., Turesson I., et al. Comparison of DNA repair protein expression and activities between human fibroblast cell lines with different radiosensitivities. Int J Cancer 2000, 85(6):845-849.
    • (2000) Int J Cancer , vol.85 , Issue.6 , pp. 845-849
    • Carlomagno, F.1    Burnet, N.G.2    Turesson, I.3
  • 39
    • 44349146591 scopus 로고    scopus 로고
    • Aberrant CDKN1A transcriptional response associates with abnormal sensitivity to radiation treatment
    • Badie C., Dziwura S., Raffy C., et al. Aberrant CDKN1A transcriptional response associates with abnormal sensitivity to radiation treatment. Br J Cancer 2008, 98:1845-1851.
    • (2008) Br J Cancer , vol.98 , pp. 1845-1851
    • Badie, C.1    Dziwura, S.2    Raffy, C.3
  • 40
    • 67749124619 scopus 로고    scopus 로고
    • Constitutive gene expression profile segregates toxicity in locally advanced breast cancer patients treated with high-dose hyperfractionated radical radiotherapy
    • Henriquez Hernandez L.A., Lara P.C., Pinar B., et al. Constitutive gene expression profile segregates toxicity in locally advanced breast cancer patients treated with high-dose hyperfractionated radical radiotherapy. Radiat Oncol 2009, 4:17.
    • (2009) Radiat Oncol , vol.4 , pp. 17
    • Henriquez Hernandez, L.A.1    Lara, P.C.2    Pinar, B.3
  • 41
    • 79251597054 scopus 로고    scopus 로고
    • A radiation-induced gene expression signature as a tool to predict acute radiotherapy-induced adverse side effects
    • Mayer C., Popanda O., Greve B., et al. A radiation-induced gene expression signature as a tool to predict acute radiotherapy-induced adverse side effects. Cancer Lett 2011, 302:20-28.
    • (2011) Cancer Lett , vol.302 , pp. 20-28
    • Mayer, C.1    Popanda, O.2    Greve, B.3
  • 42
    • 27144513287 scopus 로고    scopus 로고
    • CD4 and CD8 T-lymphocyte apoptosis can predict radiation-induced late toxicity: a prospective study in 399 patients
    • Ozsahin M., Crompton N.E., Gourgou S., et al. CD4 and CD8 T-lymphocyte apoptosis can predict radiation-induced late toxicity: a prospective study in 399 patients. Clin Cancer Res 2005, 11(20):7426-7433.
    • (2005) Clin Cancer Res , vol.11 , Issue.20 , pp. 7426-7433
    • Ozsahin, M.1    Crompton, N.E.2    Gourgou, S.3
  • 43
    • 84922449020 scopus 로고    scopus 로고
    • Late side-effects after curative intent radiotherapy: identification of hypersensitive patients for personalized strategy
    • Bourgier C., Lacombe J., Solassol J., et al. Late side-effects after curative intent radiotherapy: identification of hypersensitive patients for personalized strategy. Crit Rev Oncol Hematol 2015, 93(3):312-319.
    • (2015) Crit Rev Oncol Hematol , vol.93 , Issue.3 , pp. 312-319
    • Bourgier, C.1    Lacombe, J.2    Solassol, J.3
  • 44
    • 0030474646 scopus 로고    scopus 로고
    • Prognostic factors for acute and late skin reactions in radiotherapy patients
    • Turesson I., Nyman J., Holmberg E., Odén A. Prognostic factors for acute and late skin reactions in radiotherapy patients. Int J Radiat Oncol Biol Phys 1996, 36:1065-1075.
    • (1996) Int J Radiat Oncol Biol Phys , vol.36 , pp. 1065-1075
    • Turesson, I.1    Nyman, J.2    Holmberg, E.3    Odén, A.4
  • 45
    • 0036139437 scopus 로고    scopus 로고
    • Deterministic rather than stochastic factors explain most of the variation in the expression of skin telangiectasia after radiotherapy
    • Safwat A., Bentzen S.M., Turesson I., Hendry J.H. Deterministic rather than stochastic factors explain most of the variation in the expression of skin telangiectasia after radiotherapy. Int J Radiat Oncol Biol Phys 2002, 52(1):198-204.
    • (2002) Int J Radiat Oncol Biol Phys , vol.52 , Issue.1 , pp. 198-204
    • Safwat, A.1    Bentzen, S.M.2    Turesson, I.3    Hendry, J.H.4
  • 46
    • 0031737611 scopus 로고    scopus 로고
    • Describing patients' normal tissue reactions: concerning the possibility of individualising radiotherapy dose prescriptions based on potential predictive assays of normal tissue radiosensitivity. Steering Committee of the BioMed2 European Union Concerted Action Programme on the Development of Predictive Tests of Normal Tissue Response to Radiation Therapy
    • Burnet N.G., Johansen J., Turesson I., Nyman J., Peacock J.H. Describing patients' normal tissue reactions: concerning the possibility of individualising radiotherapy dose prescriptions based on potential predictive assays of normal tissue radiosensitivity. Steering Committee of the BioMed2 European Union Concerted Action Programme on the Development of Predictive Tests of Normal Tissue Response to Radiation Therapy. Int J Cancer 1998, 79:606-613.
    • (1998) Int J Cancer , vol.79 , pp. 606-613
    • Burnet, N.G.1    Johansen, J.2    Turesson, I.3    Nyman, J.4    Peacock, J.H.5
  • 47
    • 2642525186 scopus 로고    scopus 로고
    • Chromosomal radiosensitivity and low penetrance predisposition to cancer
    • Scott D. Chromosomal radiosensitivity and low penetrance predisposition to cancer. Cytogenet Genome Res 2004, 104:365-370.
    • (2004) Cytogenet Genome Res , vol.104 , pp. 365-370
    • Scott, D.1
  • 48
    • 0033358577 scopus 로고    scopus 로고
    • Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer?
    • Roberts S.A., Spreadborough A.R., Bulman B., Barber J.B., Evans D.G., Scott D. Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer?. Am J Hum Genet 1999, 65:784-794.
    • (1999) Am J Hum Genet , vol.65 , pp. 784-794
    • Roberts, S.A.1    Spreadborough, A.R.2    Bulman, B.3    Barber, J.B.4    Evans, D.G.5    Scott, D.6
  • 49
    • 27644479261 scopus 로고    scopus 로고
    • G(2) chromosomal radiosensitivity in Danish survivors of childhood and adolescent cancer and their offspring
    • Curwen G.B., Winther J.F., Tawn E.J., et al. G(2) chromosomal radiosensitivity in Danish survivors of childhood and adolescent cancer and their offspring. Br J Cancer 2005, 93:1038-1045.
    • (2005) Br J Cancer , vol.93 , pp. 1038-1045
    • Curwen, G.B.1    Winther, J.F.2    Tawn, E.J.3
  • 50
    • 78049517448 scopus 로고    scopus 로고
    • The heritability of G2 chromosomal radiosensitivity and its association with cancer in Danish cancer survivors and their offspring
    • Curwen G.B., Cadwell K.K., Winther J.F., et al. The heritability of G2 chromosomal radiosensitivity and its association with cancer in Danish cancer survivors and their offspring. Int J Radiat Biol 2010, 86:986-995.
    • (2010) Int J Radiat Biol , vol.86 , pp. 986-995
    • Curwen, G.B.1    Cadwell, K.K.2    Winther, J.F.3
  • 51
    • 44149120922 scopus 로고    scopus 로고
    • Evidence for significant heritability of apoptotic and cell cycle responses to ionising radiation
    • Finnon P., Robertson N., Dziwura S., et al. Evidence for significant heritability of apoptotic and cell cycle responses to ionising radiation. Hum Genet 2008, 123:485-493.
    • (2008) Hum Genet , vol.123 , pp. 485-493
    • Finnon, P.1    Robertson, N.2    Dziwura, S.3
  • 52
    • 34447305483 scopus 로고    scopus 로고
    • Heritability of susceptibility to ionizing radiation-induced apoptosis of human lymphocyte subpopulations
    • Schmitz A., Bayer J., Dechamps N., Goldin L., Thomas G. Heritability of susceptibility to ionizing radiation-induced apoptosis of human lymphocyte subpopulations. Int J Radiat Oncol Biol Phys 2007, 68:1169-1177.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 1169-1177
    • Schmitz, A.1    Bayer, J.2    Dechamps, N.3    Goldin, L.4    Thomas, G.5
  • 53
    • 33745728456 scopus 로고    scopus 로고
    • Mutagen sensitivity has high heritability: evidence from a twin study
    • Wu X., Spitz M.R., Amos C.I., et al. Mutagen sensitivity has high heritability: evidence from a twin study. Cancer Res 2006, 66:5993-5996.
    • (2006) Cancer Res , vol.66 , pp. 5993-5996
    • Wu, X.1    Spitz, M.R.2    Amos, C.I.3
  • 54
    • 19544379326 scopus 로고    scopus 로고
    • Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms
    • Girard P.M., Kysela B., Harer C.J., Doherty A.J., Jeggo P.A. Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms. Hum Mol Genet 2004, 13:2369-2376.
    • (2004) Hum Mol Genet , vol.13 , pp. 2369-2376
    • Girard, P.M.1    Kysela, B.2    Harer, C.J.3    Doherty, A.J.4    Jeggo, P.A.5
  • 55
    • 0025345637 scopus 로고
    • Sensitivity of human diploid fibroblast cell strains from various genetic disorders to acute and protracted radiation exposure
    • Little J.B., Nove J. Sensitivity of human diploid fibroblast cell strains from various genetic disorders to acute and protracted radiation exposure. Radiat Res 1990, 123:87-92.
    • (1990) Radiat Res , vol.123 , pp. 87-92
    • Little, J.B.1    Nove, J.2
  • 56
    • 58949092475 scopus 로고    scopus 로고
    • Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype
    • Barnett G.C., West C.M.L., Dunning A.M., et al. Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype. Nat Rev Cancer 2009, 9(2):134-142.
    • (2009) Nat Rev Cancer , vol.9 , Issue.2 , pp. 134-142
    • Barnett, G.C.1    West, C.M.L.2    Dunning, A.M.3
  • 57
    • 84920023936 scopus 로고    scopus 로고
    • Radiogenomics: the search for genetic predictors of radiotherapy response
    • Kerns S.L., West C.M., Andreassen C.N., et al. Radiogenomics: the search for genetic predictors of radiotherapy response. Future Oncol 2014, 10(15):2391-2406.
    • (2014) Future Oncol , vol.10 , Issue.15 , pp. 2391-2406
    • Kerns, S.L.1    West, C.M.2    Andreassen, C.N.3
  • 58
    • 39749142193 scopus 로고    scopus 로고
    • Genetic markers for prediction of normal tissue toxicity after radiotherapy
    • Alsner J., Andreassen C.N., Overgaard J. Genetic markers for prediction of normal tissue toxicity after radiotherapy. Semin Radiat Oncol 2008, 18:126-135.
    • (2008) Semin Radiat Oncol , vol.18 , pp. 126-135
    • Alsner, J.1    Andreassen, C.N.2    Overgaard, J.3
  • 59
    • 67649198795 scopus 로고    scopus 로고
    • Genetic variation in normal tissue toxicity induced by ionizing radiation
    • Popanda O., Marquardt J.U., Chang-Claude J., Schmezer P. Genetic variation in normal tissue toxicity induced by ionizing radiation. Mutat Res 2009, 667:58-69.
    • (2009) Mutat Res , vol.667 , pp. 58-69
    • Popanda, O.1    Marquardt, J.U.2    Chang-Claude, J.3    Schmezer, P.4
  • 60
    • 84864868856 scopus 로고    scopus 로고
    • A replicated association between polymorphisms near TNFα and risk for adverse reactions to radiotherapy
    • Talbot C.J., Tanteles G.A., Barnett G.C., et al. A replicated association between polymorphisms near TNFα and risk for adverse reactions to radiotherapy. Br J Cancer 2012, 107(4):748-753.
    • (2012) Br J Cancer , vol.107 , Issue.4 , pp. 748-753
    • Talbot, C.J.1    Tanteles, G.A.2    Barnett, G.C.3
  • 61
    • 84855321526 scopus 로고    scopus 로고
    • Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study
    • Barnett G.C., Coles C.E., Elliott R.M., et al. Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study. Lancet Oncol 2012, 13(1):65-77.
    • (2012) Lancet Oncol , vol.13 , Issue.1 , pp. 65-77
    • Barnett, G.C.1    Coles, C.E.2    Elliott, R.M.3
  • 62
    • 84871182048 scopus 로고    scopus 로고
    • Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity
    • Barnett G.C., Elliott R.M., Alsner J., et al. Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity. Radiother Oncol 2012, 105(3):289-295.
    • (2012) Radiother Oncol , vol.105 , Issue.3 , pp. 289-295
    • Barnett, G.C.1    Elliott, R.M.2    Alsner, J.3
  • 63
    • 78549233654 scopus 로고    scopus 로고
    • Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer
    • Kerns S.L., Ostrer H., Stock R., et al. Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys 2010, 78(5):1292-1300.
    • (2010) Int J Radiat Oncol Biol Phys , vol.78 , Issue.5 , pp. 1292-1300
    • Kerns, S.L.1    Ostrer, H.2    Stock, R.3
  • 64
    • 84881475896 scopus 로고    scopus 로고
    • Genome-wide association study identifies a region on chromosome 11q14.3 associated with late rectal bleeding following radiation therapy for prostate cancer
    • Kerns S.L., Stock R.G., Stone N.N., et al. Genome-wide association study identifies a region on chromosome 11q14.3 associated with late rectal bleeding following radiation therapy for prostate cancer. Radiother Oncol 2013, 107(3):372-376.
    • (2013) Radiother Oncol , vol.107 , Issue.3 , pp. 372-376
    • Kerns, S.L.1    Stock, R.G.2    Stone, N.N.3
  • 65
    • 84856395883 scopus 로고    scopus 로고
    • Standardized Total Average Toxicity (STAT) score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies
    • Barnett G.C., West C.M.L., Coles C.E., et al. Standardized Total Average Toxicity (STAT) score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies. Int J Radiat Oncol Biol Phys 2012, 82(3):1065-1074.
    • (2012) Int J Radiat Oncol Biol Phys , vol.82 , Issue.3 , pp. 1065-1074
    • Barnett, G.C.1    West, C.M.L.2    Coles, C.E.3
  • 66
    • 84902545584 scopus 로고    scopus 로고
    • A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity
    • Barnett G.C., Thompson D., Fachal L., et al. A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity. Radiother Oncol 2014, 111(2):178-185.
    • (2014) Radiother Oncol , vol.111 , Issue.2 , pp. 178-185
    • Barnett, G.C.1    Thompson, D.2    Fachal, L.3
  • 67
    • 84905580203 scopus 로고    scopus 로고
    • A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1
    • Fachal L., Gómez-Caamaño A., Barnett G.C., et al. A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1. Nat Genet 2014, 46(8):891-894.
    • (2014) Nat Genet , vol.46 , Issue.8 , pp. 891-894
    • Fachal, L.1    Gómez-Caamaño, A.2    Barnett, G.C.3
  • 68
    • 69949163710 scopus 로고    scopus 로고
    • Genetic variants and normal tissue toxicity after radiotherapy: a systematic review
    • Andreassen C.N., Alsner J. Genetic variants and normal tissue toxicity after radiotherapy: a systematic review. Radiother Oncol 2009, 92:299-309.
    • (2009) Radiother Oncol , vol.92 , pp. 299-309
    • Andreassen, C.N.1    Alsner, J.2
  • 71
    • 33646914155 scopus 로고    scopus 로고
    • Genetic predictors of adverse radiotherapy effects: the Gene-PARE project
    • Ho A.Y., Atencio D.P., Peters S., et al. Genetic predictors of adverse radiotherapy effects: the Gene-PARE project. Int J Radiat Oncol Biol Phys 2006, 65:646-655.
    • (2006) Int J Radiat Oncol Biol Phys , vol.65 , pp. 646-655
    • Ho, A.Y.1    Atencio, D.P.2    Peters, S.3
  • 72
    • 34548662650 scopus 로고    scopus 로고
    • Haplotype-based analysis of genes associated with risk of adverse skin reactions after radiotherapy in breast cancer patients
    • Suga T., Ishikawa A., Kohda M., et al. Haplotype-based analysis of genes associated with risk of adverse skin reactions after radiotherapy in breast cancer patients. Int J Radiat Oncol Biol Phys 2007, 69:685-693.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 685-693
    • Suga, T.1    Ishikawa, A.2    Kohda, M.3
  • 73
    • 84871202486 scopus 로고    scopus 로고
    • Association of a XRCC3 polymorphism and rectum mean dose with the risk of acute radio-induced gastrointestinal toxicity in prostate cancer patients
    • Fachal L., Gómez-Caamaño A., Peleteiro P., et al. Association of a XRCC3 polymorphism and rectum mean dose with the risk of acute radio-induced gastrointestinal toxicity in prostate cancer patients. Radiother Oncol 2012, 105(3):321-328.
    • (2012) Radiother Oncol , vol.105 , Issue.3 , pp. 321-328
    • Fachal, L.1    Gómez-Caamaño, A.2    Peleteiro, P.3
  • 74
    • 84896080866 scopus 로고    scopus 로고
    • STROGAR - STrengthening the Reporting Of Genetic Association studies in Radiogenomics
    • Kerns S.L., Ruysscher D.D., Andreassen C.N., et al. STROGAR - STrengthening the Reporting Of Genetic Association studies in Radiogenomics. Radiother Oncol 2014, 110(1):182-188.
    • (2014) Radiother Oncol , vol.110 , Issue.1 , pp. 182-188
    • Kerns, S.L.1    Ruysscher, D.D.2    Andreassen, C.N.3
  • 75
    • 84928761946 scopus 로고    scopus 로고
    • Prediction of breast cancer risk based on profiling with common genetic variants
    • djv036
    • Mavaddat N., Pharoah P.D., Michailidou K., et al. Prediction of breast cancer risk based on profiling with common genetic variants. J Natl Cancer Inst 2015, 107(5). djv036.
    • (2015) J Natl Cancer Inst , vol.107 , Issue.5
    • Mavaddat, N.1    Pharoah, P.D.2    Michailidou, K.3
  • 76
    • 80053563437 scopus 로고    scopus 로고
    • Genetics and genomics of radiotherapy toxicity: towards prediction
    • West C.M., Barnett G.C. Genetics and genomics of radiotherapy toxicity: towards prediction. Genome Med 2011, 3(8):52.
    • (2011) Genome Med , vol.3 , Issue.8 , pp. 52
    • West, C.M.1    Barnett, G.C.2
  • 77
    • 84857565239 scopus 로고    scopus 로고
    • Genome-wide association studies and prediction of normal tissue toxicity
    • West C.M., Dunning A.M., Rosenstein B.S. Genome-wide association studies and prediction of normal tissue toxicity. Semin Radiat Oncol 2012, 22:91-99.
    • (2012) Semin Radiat Oncol , vol.22 , pp. 91-99
    • West, C.M.1    Dunning, A.M.2    Rosenstein, B.S.3
  • 78
    • 0029928295 scopus 로고    scopus 로고
    • Normal tissue radiosensitivity - how important is it?
    • Burnet N.G., Wurm R., Nyman J., Peacock J.H. Normal tissue radiosensitivity - how important is it?. Clin Oncol 1996, 8:25-34.
    • (1996) Clin Oncol , vol.8 , pp. 25-34
    • Burnet, N.G.1    Wurm, R.2    Nyman, J.3    Peacock, J.H.4
  • 79
    • 20244364373 scopus 로고
    • Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a randomized trial of the EORTC cooperative group of radiotherapy
    • Horiot J.C., Le Fur R., N'Guyen T., et al. Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a randomized trial of the EORTC cooperative group of radiotherapy. Radiother Oncol 1992, 25(4):231-241.
    • (1992) Radiother Oncol , vol.25 , Issue.4 , pp. 231-241
    • Horiot, J.C.1    Le Fur, R.2    N'Guyen, T.3
  • 80
    • 38149102436 scopus 로고    scopus 로고
    • Question of dose, fractionation and technique: ingredients for testing hypofractionation in prostate cancer - the CHHiP trial
    • Khoo V.S., Dearnaley D.P. Question of dose, fractionation and technique: ingredients for testing hypofractionation in prostate cancer - the CHHiP trial. Clin Oncol (R Coll Radiol) 2008, 20(1):12-14.
    • (2008) Clin Oncol (R Coll Radiol) , vol.20 , Issue.1 , pp. 12-14
    • Khoo, V.S.1    Dearnaley, D.P.2
  • 81
    • 67651087472 scopus 로고    scopus 로고
    • To bleed or not to bleed. A prediction based on individual gene profiling combined with dose-volume histogram shapes in prostate cancer patients undergoing three-dimensional conformal radiation therapy
    • Valdagni R., Rancati T., Ghilotti M., et al. To bleed or not to bleed. A prediction based on individual gene profiling combined with dose-volume histogram shapes in prostate cancer patients undergoing three-dimensional conformal radiation therapy. Int J Radiat Oncol Biol Phys 2009, 74(5):1431-1440.
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , Issue.5 , pp. 1431-1440
    • Valdagni, R.1    Rancati, T.2    Ghilotti, M.3
  • 82
    • 78651478579 scopus 로고    scopus 로고
    • Development, external validation and clinical usefulness of a practical prediction model for radiation-induced dysphagia in lung cancer patients
    • Dehing-Oberije C., De Ruysscher D., Petit S., et al. Development, external validation and clinical usefulness of a practical prediction model for radiation-induced dysphagia in lung cancer patients. Radiother Oncol 2010, 97:455-461.
    • (2010) Radiother Oncol , vol.97 , pp. 455-461
    • Dehing-Oberije, C.1    De Ruysscher, D.2    Petit, S.3
  • 83
    • 76449113556 scopus 로고    scopus 로고
    • Accurate accumulation of dose for improved understanding of radiation effects in normal tissue
    • Jaffray D.A., Lindsay P.E., Brock K.K., Deasy J.O., Tomé W.A. Accurate accumulation of dose for improved understanding of radiation effects in normal tissue. Int J Radiat Oncol Biol Phys 2010, 76(3 Suppl.):S135-S139.
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , Issue.3 , pp. S135-S139
    • Jaffray, D.A.1    Lindsay, P.E.2    Brock, K.K.3    Deasy, J.O.4    Tomé, W.A.5
  • 84
    • 84907494208 scopus 로고    scopus 로고
    • Random variation in rectal position during radiotherapy for prostate cancer is up to three times higher than that predicted from prostate motion
    • Scaife J.E., Harrison K., Romanchikova M., et al. Random variation in rectal position during radiotherapy for prostate cancer is up to three times higher than that predicted from prostate motion. Br J Radiol 2014, 87(1042):20140343.
    • (2014) Br J Radiol , vol.87 , Issue.1042 , pp. 20140343
    • Scaife, J.E.1    Harrison, K.2    Romanchikova, M.3
  • 85
    • 84941321708 scopus 로고    scopus 로고
    • Accumulated dose volumes to the rectum are different from those planned in approximately 80% of patients treated with helical tomotherapy for prostate cancer
    • Scaife J., Harrison K., Romanchikova M., Thomas S., Jena R., Burnet N.G. Accumulated dose volumes to the rectum are different from those planned in approximately 80% of patients treated with helical tomotherapy for prostate cancer. Clin Oncol 2015, 27(3):e3-e4.
    • (2015) Clin Oncol , vol.27 , Issue.3 , pp. e3-e4
    • Scaife, J.1    Harrison, K.2    Romanchikova, M.3    Thomas, S.4    Jena, R.5    Burnet, N.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.