Incidence of Late Rectal and Urinary Toxicities After Three-Dimensional Conformal Radiotherapy and Intensity-Modulated Radiotherapy for Localized Prostate Cancer

International Journal of Radiation Oncology Biology Physics

Volumn 70, Issue 4, 2008, Pages 1124-1129

  Zelefsky, Michael J ^a   Levin, Emily J ^a   Hunt, Margie ^a   Yamada, Yoshiya ^a   Shippy, Alison M ^a   Jackson, Andrew ^a   Amols, Howard I ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Dose escalation; IMRT; Prostate cancer; Radiotherapy; Toxicity

Indexed keywords

DOSIMETERS; HEALTH RISKS; RADIOTHERAPY; THREE DIMENSIONAL; TOXICITY; TUMORS;

DOSE ESCALATION; PROSTATE CANCER; RADIATION DOSE;

ONCOLOGY;

ANTIANDROGEN;

ADULT; AGED; ARTICLE; CANCER INCIDENCE; CANCER RADIOTHERAPY; COMPUTER ASSISTED RADIOTHERAPY; CONTROLLED STUDY; GASTROINTESTINAL SYMPTOM; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE; RECTUM DISEASE; URINARY DYSFUNCTION;

AGED; AGED, 80 AND OVER; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PROCTITIS; PROSTATIC NEOPLASMS; RADIATION INJURIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; RADIOTHERAPY, INTENSITY-MODULATED; RECTUM; TIME FACTORS; URINARY BLADDER; UROGENITAL SYSTEM;

EID: 39749192109     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.11.044     Document Type: Article

References (20)

1. Pollack A., Zagars G.K., Smith L.G., et al. Preliminary results of a randomized radiotherapy dose-escalation study comparing 70 Gy with 78 Gy for prostate cancer. J Clin Oncol 18 (2000) 3904-3911
2. Zietman A.L., DeSilvio M.L., Slater J.D., et al. Comparison of conventional-dose vs high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: A randomized controlled trial. JAMA 294 (2005) 1233-1239
3. Peeters S.T.H., Heemsbergen W.D., Koper P.C.M., et al. Dose-response in radiotherapy for localized prostate cancer: Results of the Dutch multicenter randomized Phase III trial comparing 68 Gy of radiotherapy with 78 Gy. J Clin Oncol 24 (2006) 1990-1996
4. Dearnaley D.P., Sydes M.R., Graham J.D., et al. Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: First results from the MRC RT01 randomised controlled trial. Lancet Oncol 8 (2007) 475-487
5. Zelefsky M.J., Leibel S.A., Gaudin P.B., et al. Dose escalation with three-dimensional conformal radiation therapy affects the outcome in prostate cancer. Int J Radiat Oncol Biol Phys 41 (1998) 491-500
6. Zelefsky M.J., Hunt M.A., Fuks Z., et al. Long-term distant metastases-free survival and cause-specific survival outcomes after high dose conformal radiotherapy for clinically localized prostate cancer. Int J Radiat Oncol Biol Phys 66 (2006) S9
7. Jacob R., Hanlon A.L., Horwitz E.M., et al. The relationship of increasing radiotherapy dose to reduced distant metastases and mortality in men with prostate cancer. Cancer 100 (2004) 538-543
8. Pilepich M.M.V., Krall J.J.M., Sause W.W.T., et al. Correlation of radiotherapeutic parameters and treatment related morbidity in carcinoma of the prostate-analysis of RTOG study 75-06. Int J Radiat Oncol Biol Phys 13 (1987) 351-357
9. Smit W.W.G., Helle P.P.A., van Putten W.W.L., et al. Late radiation damage in prostate cancer patients treated by high dose external radiotherapy in relation to rectal dose. Int J Radiat Oncol Biol Phys 18 (1990) 23-29
10. Hanks G.E., Hanlon A.L., Schultheiss T.E., et al. Dose escalation with 3D conformal treatment: Five year outcomes, treatment optimization, and future directions. Int J Radiat Oncol Biol Phys 41 (1998) 501-510
11. Zelefsky M.J., Cowen D., Fuks Z., et al. Long term tolerance of high dose three-dimensional conformal radiotherapy in patients with localized prostate carcinoma. Cancer 85 (1999) 2460-2468
12. Zelefsky M.J., Chan H., Hunt M., et al. Long-term outcome of high dose intensity modulated radiation therapy for patients with clinically localized prostate cancer. J Urol 176 (2006) 1415-1419
13. Gardner B.G., Zietman A.L., Shipley W.U., et al. Late normal tissue sequelae in the second decade after high dose radiation therapy with combined photons and conformal protons for locally advanced prostate cancer. J Urol 167 (2002) 123-126
14. Burman C., Chui C.S., Kutcher G., et al. Planning, delivery, and quality assurance of intensity-modulated radiotherapy using dynamic multileaf collimator: A strategy for large-scale implementation for the treatment of carcinoma of the prostate. Int J Radiat Oncol Biol Phys 39 (1997) 863-873
15. Schultheiss T.E., Hanks G.E., Hunt M.A., et al. Incidence of and factors related to late complications in conformal and conventional radiation treatment of cancer of the prostate. Int J Radiat Oncol Biol Phys 54 (2002) 442-449
16. Denham J.W., O'Brien P.C., Dunstan R.H., et al. Is there more than one late radiation proctitis syndrome?. Radiother Oncol 32 (1995) 643-649
17. O'Brien P.C., Franklin C.I., Poulsen M.G., et al. Acute symptoms, not rectally administered sucralfate, predict for late radiation proctitis: Longer term follow-up of a Phase III trial-Trans-Tasman Radiation Oncology Group. Int J Radiat Oncol Biol Phys 54 (2002) 442-449
18. Vargas C., Martinez A., Kestin L.L., et al. Dose-volume analysis of predictors for chronic rectal toxicity after treatment of prostate cancer with adaptive image-guided radiotherapy. Int J Radiat Oncol Biol Phys 62 (2005) 1297-1308
19. Heemsbergen W.D., Peeters S.T.H., Koper P.C.M., et al. Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer patients: consequential late damage. Int J Radiat Oncol Biol Phys 66 (2006) 3-10
20. Heemsbergen W.D., Hoofeman M.S., Hart G.A., et al. Gastrointestinal toxicity and its relation to dose distributions in the anorectal region of prostate cancer patients treated with radiotherapy. Int J Radiat Oncol Biol Phys 61 (2005) 1011-1018