Long-term endurance exercise in humans stimulates cell fusion of myoblasts along with fusogenic endogenous retroviral genes in vivo

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Frese, Sebastian ^a,b,c   Ruebner, Matthias ^d   Suhr, Frank ^a   Konou, Thierry M ^a   Tappe, Kim A ^a   Toigo, Marco ^c,e   Jung, Hans H ^b   Henke, Christine ^d   Steigleder, Ruth ^d   Strissel, Pamela L ^d   Huebner, Hanna ^d   Beckmann, Matthias W ^d   Van Der Keylen, Piet ^f   Schoser, Benedikt ^h   Schiffer, Thorsten ^a   Frese, Laura ^g   Bloch, Wilhelm ^a   Strick, Reiner ^d  

^a GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c ETH ZURICH   (Switzerland)

^d UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^e UNIVERSITY OF ZURICH   (Switzerland)

^f UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^g UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^h LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYCLIC AMP DEPENDENT PROTEIN KINASE; ERV3 PROTEIN; EXCITATORY AMINO ACID TRANSPORTER; EXCITATORY AMINO ACID TRANSPORTER 4; EXCITATORY AMINO ACID TRANSPORTER 5; MYOSIN HEAVY CHAIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOID X RECEPTOR ALPHA; TRANSCRIPTION FACTOR PAX7; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADOLESCENT; ARTICLE; BODY MASS; CELL FUSION; CONTROLLED STUDY; CYCLING; ENDURANCE TRAINING; ERV3 GENE; EXERCISE INTENSITY; GENE CONTROL; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LONG TERM EXPOSURE; MALE; MUSCLE BIOPSY; MUSCLE DEVELOPMENT; MUSCLE GROWTH; MYOBLAST; OSTEOCLAST; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RETROVIRIDAE; RNA ISOLATION; SARCOLEMMA; SATELLITE CELL; SYNCYTIN 2 GENE; SYNCYTIN 3 GENE; VIRUS GENE; CELL CULTURE; CYTOLOGY; ENDOGENOUS RETROVIRUS; ENDURANCE; EXERCISE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SKELETAL MUSCLE CELL; SKELETAL MUSCLE SATELLITE CELL; TIME FACTOR; ULTRAMICROTOMY; VIROLOGY;

ADOLESCENT; BICYCLING; CELL FUSION; CELLS, CULTURED; CRYOULTRAMICROTOMY; ENDOGENOUS RETROVIRUSES; EXERCISE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES, VIRAL; HUMANS; MALE; MUSCLE FIBERS, SKELETAL; MYOBLASTS; PHYSICAL ENDURANCE; REAL-TIME POLYMERASE CHAIN REACTION; SATELLITE CELLS, SKELETAL MUSCLE; TIME FACTORS;

EID: 84941299539     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132099     Document Type: Article

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