The actin regulator N-WASp is required for muscle-cell fusion in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 28, 2012, Pages 11211-11216

  Gruenbaum Cohen, Yael ^a   Harel, Itamar ^a   Umansky, Kfir Baruch ^a   Tzahor, Eldad ^a   Snapper, Scott B ^b   Shilo, Ben Zion ^a   Schejter, Eyal D ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Actin nucleation; Myotube formation

Indexed keywords

NEURAL WISKOTT ALDRICH SYNDROME PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FUSION; CELL MOTILITY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; INVERTEBRATE; MICROFILAMENT; MONONUCLEAR CELL; MORPHOGENESIS; MOUSE; MUSCLE DEVELOPMENT; MUSCLE MASS; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SKELETAL MUSCLE SATELLITE CELL; VERTEBRATE;

ACTINS; ANIMALS; CELL DIFFERENTIATION; CELL FUSION; CELLS, CULTURED; CROSSES, GENETIC; DROSOPHILA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HETEROZYGOTE; MICE; MICE, INBRED ICR; MODELS, BIOLOGICAL; MUSCLE DEVELOPMENT; MUSCLES; TIME FACTORS; WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL;

INVERTEBRATA; MAMMALIA; MUS; VERTEBRATA;

EID: 84863977654     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1116065109     Document Type: Article

References (39)

1. Rochlin K, Yu S, Roy S, Baylies MK (2010) Myoblast fusion: When it takes more to make one. Dev Biol 341:66-83.
2. Simionescu A, Pavlath GK (2011) Molecular mechanisms of myoblast fusion across species. Adv Exp Med Biol 713:113-135.
3. Bismuth K, Relaix F (2010) Genetic regulation of skeletal muscle development. Exp Cell Res 316:3081-3086.
4. Buckingham M (2006) Myogenic progenitor cells and skeletal myogenesis in vertebrates. Curr Opin Genet Dev 16:525-532.
5. Haralalka S, Abmayr SM (2010) Myoblast fusion in Drosophila. Exp Cell Res 316:3007-3013.
6. Onel SF, Renkawitz-Pohl R (2009) FuRMAS: Triggering myoblast fusion in Drosophila. Dev Dyn 238:1513-1525.
7. Richardson BE, Nowak SJ, Baylies MK (2008) Myoblast fusion in fly and vertebrates: New genes, new processes and new perspectives. Traffic 9:1050-1059. (Pubitemid 351916882)
8. Snapper SB, et al. (2001) N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility. Nat Cell Biol 3:897-904. (Pubitemid 32952254)
9. Cotta-de-Almeida V, et al. (2007) Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development. Proc Natl Acad Sci USA 104:15424-15429. (Pubitemid 47502933)
10. Tallquist MD, Weismann KE, Hellström M, Soriano P (2000) Early myotome specification regulates PDGFA expression and axial skeleton development. Development 127:5059-5070. (Pubitemid 32000664)
11. Chen JC, Mortimer J, Marley J, Goldhamer DJ (2005) MyoD-cre transgenic mice: a model for conditional mutagenesis and lineage tracing of skeletal muscle. Genesis 41:116-121.
12. Wamhoff BR, Sinha S, Owens GK (2007) Conditional mouse models to study developmental and pathophysiological gene function in muscle. Handb Exp Pharmacol 178:441-468.
13. Millard TH, Sharp SJ, Machesky LM (2004) Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex. Biochem J 380:1-17. (Pubitemid 38725724)
14. Engleka KA, et al. (2005) Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives. Dev Biol 280:396-406. (Pubitemid 40692140)
15. Buckingham M, et al. (2003) The formation of skeletal muscle: From somite to limb. J Anat 202:59-68. (Pubitemid 36503969)
16. Beauchamp JR, et al. (2000) Expression of CD34 and Myf5 defines the majority of quiescent adult skeletal muscle satellite cells. J Cell Biol 151:1221-1234.
17. Radice GL, et al. (1997) Developmental defects in mouse embryos lacking N-cadherin. Dev Biol 181:64-78. (Pubitemid 27079635)
18. Charrasse S, Meriane M, Comunale F, Blangy A, Gauthier-Rouvière C (2002) N-cadherindependent cell-cell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts. J Cell Biol 158:953-965. (Pubitemid 35001085)
19. Haralalka S, et al. (2011) Asymmetric Mbc, active Rac1 and F-actin foci in the fusion-competent myoblasts during myoblast fusion in Drosophila. Development 138:1551-1562.
20. Jin P, et al. (2011) Competition between Blown fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo. Dev Cell 20:623-638.
21. Massarwa R, Carmon S, Shilo BZ, Schejter ED (2007) WIP/WASp-based actin-polymerization machinery is essential for myoblast fusion in Drosophila. Dev Cell 12: 557-569. (Pubitemid 46523636)
22. Sohn RL, et al. (2009) A role for nephrin, a renal protein, in vertebrate skeletal muscle cell fusion. Proc Natl Acad Sci USA 106:9274-9279.
23. Vasyutina E, Martarelli B, Brakebusch C, Wende H, Birchmeier C (2009) The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse. Proc Natl Acad Sci USA 106:8935-8940.
24. Laurin M, et al. (2008) The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. Proc Natl Acad Sci USA 105:15446-15451.
25. Nowak SJ, Nahirney PC, Hadjantonakis AK, Baylies MK (2009) Nap1-mediated actin remodeling is essential for mammalian myoblast fusion. J Cell Sci 122:3282-3293.
26. Gildor B, Massarwa R, Shilo BZ, Schejter ED (2009) The SCAR and WASp nucleation-promoting factors act sequentially to mediate Drosophila myoblast fusion. EMBO Rep 10:1043-1050.
27. Kim S, et al. (2007) A critical function for the actin cytoskeleton in targeted exocytosis of prefusion vesicles during myoblast fusion. Dev Cell 12:571-586. (Pubitemid 46523641)
28. Mukherjee P, Gildor B, Shilo BZ, VijayRaghavan K, Schejter ED (2011) The actin nucleator WASp is required for myoblast fusion during adult Drosophila myogenesis. Development 138:2347-2357.
29. Richardson BE, Beckett K, Nowak SJ, Baylies MK (2007) SCAR/WAVE and Arp2/3 are crucial for cytoskeletal remodeling at the site of myoblast fusion. Development 134:4357-4367.
30. Schäfer G, et al. (2007) The Wiskott-Aldrich syndrome protein (WASP) is essential for myoblast fusion in Drosophila. Dev Biol 304:664-674. (Pubitemid 46527569)
31. Schröter RH, et al. (2004) kette and blown fuse interact genetically during the second fusion step of myogenesis in Drosophila. Development 131:4501-4509. (Pubitemid 39409691)
32. Sens KL, et al. (2010) An invasive podosome-like structure promotes fusion pore formation during myoblast fusion. J Cell Biol 191:1013-1027.
33. Duan R, Gallagher PJ (2009) Dependence of myoblast fusion on a cortical actin wall and nonmuscle myosin IIA. Dev Biol 325:374-385.
34. Abmayr SM, Pavlath GK (2012) Myoblast fusion: Lessons from flies and mice. Development 139:641-656.
35. Harel I, et al. (2009) Distinct origins and genetic programs of head muscle satellite cells. Dev Cell 16:822-832.
36. Ono Y, et al. (2011) BMP signalling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells. Cell Death Differ 18:222-234.
37. DeLaurier A, Schweitzer R, Logan M (2006) Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb. Dev Biol 299:22-34. (Pubitemid 44528397)
38. Tirosh-Finkel L, Elhanany H, Rinon A, Tzahor E (2006) Mesoderm progenitor cells of common origin contribute to the head musculature and the cardiac outflow tract. Development 133:1943-1953. (Pubitemid 43881260)
39. Aziz-Aloya RB, et al. (1998) Expression of AML1-d, a short human AML1 isoform, in embryonic stem cells suppresses in vivo tumor growth and differentiation. Cell Death Differ 5:765-773. (Pubitemid 28439117)