A urine metabonomics study of chronic renal failure and intervention effects of total aglycone extracts of Scutellaria baicalensis in 5/6 nephrectomy rats

RSC Advances

Volumn 5, Issue 92, 2015, Pages 75612-75621

  Fang, Junwei ^a   Wang, Wenyu ^a,b   Sun, Shujun ^a   Wang, Yang ^a   Li, Qianhua ^a   Lu, Xiong ^a   Hao, Zhihui ^c   Zhang, Yongyu ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b MacroStat ^*  (China)

^c QINGDAO AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CHEMICAL ANALYSIS; DRUG PRODUCTS; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINE; MERCURY COMPOUNDS; METABOLISM; PATTERN RECOGNITION; UREA;

BLOOD UREA NITROGENS; CHRONIC RENAL FAILURE; MERCURIC CHLORIDE; METABOLIC PATHWAYS; SCUTELLARIA BAICALENSIS; SHAM OPERATIONS; THERAPEUTIC POTENTIALS; TRADITIONAL CHINESE MEDICINE;

RATS;

EID: 84941242198     PISSN: None     EISSN: 20462069     Source Type: Journal    
DOI: 10.1039/c5ra12710f     Document Type: Article

References (35)

1. A. M. Torres M. Mac Laughlin A. Muller A. Brandoni N. Anzai H. Endou Altered renal elimination of organic anions in rats with chronic renal failure Biochim. Biophys. Acta, Mol. Basis Dis. 2005 1740 29 37
2. J. R. Lu, H. Y. Han, J. Chen, C. X. Xiong, X. H. Wang, J. Hu, X. F. Chen and L. Ma, Protective Effects of Bu-Shen-Huo-Xue Formula against 5/6 Nephrectomy-Induced Chronic Renal Failure in Rats, J. Evidence-Based Complementary Altern. Med., 2014, 1, 589846
3. Z. H. Sha P. Fu L. Zhou W. X. Tang F. Liu J. Li Experimental Research on chronic renal failure induced by 5/6 nephrectomy Sichuan Journal of Zoology 2005 25 632 634
4. X. J. Gou Q. Tao Q. Feng J. H. Peng S. J. Sun H. J. Cao N. N. Zheng Y. Y. Zhang Y. Y. Hu P. Liu Urinary metabonomics characterization of liver fibrosis induced by CCl4 in rats and intervention effects of Xia Yu Xue Decoction J. Pharm. Biomed. Anal. 2013 74 62 65
5. L. L. Song H. Y. Liu Y. Wang et al. Application of GC/MS-based metabonomic profiling in studying the therapeutic effects of Huangbai-Zhimu herb-pair (HZ) extract on streptozotocin-induced type 2 diabetes in mice J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2015 997 96 104
6. H. L. Li Research progress of Scutellaria baicalensis Chemical Engineering & Equipment 2008 4 100 102
7. P. Parajuli N. Joshee A. M. Rimando S. Mittal A. K. Yadav In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids Planta Med. 2009 75 41 48
8. Y. Y. Zhang Y. Guo M. Onda K. Hahimoto Y. Ikeya M. Okada M. Maruno Four flavonoids from Scutellaria baicalensis Phytochemistry 1994 35 511 524
9. Y. Y. Zhang Y. Guo H. Ageta Y. Harigaya M. Onda K. Hahimoto Y. Ikeya M. Okada M. Maruno Studies on the constituents of roots of Scutellaria planipes Planta Med. 1997 63 536 539
10. J. Xing X. Y. Chen D. F. Zhong Absorption and enterohepatic circulation of baicalin in rats Life Sci. 2005 78 140 146
11. Q. M. Che X. L. Huang Y. M. Li K. Zhang H. Akao X. Hattori Studies on Metabolites of Baicalin in Human Urine China J. Chin. Mater. Med. 2001 26 768 7699
12. L. M. Ai X. P. Zhang B. H. Li Treatment status of chronic renal failure by traditional Chinese medicine Acta Chin. Med. Pharmacol. 2013 41 84 87
13. H. D. Xie K. Yang H. D. Mu S. D. Wei Y. Y. Zhang C. H. Liu The effect of extracted Scutellaria on renal interstitial fibrosis rats and its antioxidant mechanism Chinese Journal of Integrated Traditional and Western Nephrology 2009 10 240 242
14. R. Platt M. H. Roscoe F. W. Smith Experimental renal failure Clin. Sci. 1952 11 217 231
15. S. J. Sun, J. Y. Dai, J. W. Fang, X. J. Gou, H. J. Cao, N. N. Zheng, Y. Wang, W. Zhang, Y. Y. Zhang, W. Jia and Y. Y. Hu, Differences of Excess and Deficiency Zheng in Patients with Chronic Hepatitis B by Urinary Metabonomics, J. Evidence-Based Complementary Altern. Med., 2013, 1, 738245
16. X. Gao E. Pujos-Guillot J. F. Martin P. Galan C. Juste W. Jia J. L. Sebedio Metabolite analysis of human fecal water by gas chromatography/mass spectrometry with ethyl chloroformate derivatization Anal. Biochem. 2009 393 163 175
17. M. MacKinnon S. Shurraw A. Akbari G. A. Knoll J. Jaffey H. D. Clark Combination therapy with an angiotensin receptor blocker and an ACE inhibitor in proteinuric renal disease: a systematic review of the efficacy and safety data Am. J. Kidney Dis. 2006 48 8 20
18. X. J. Wang A. H. Zhang G. L. Yan W. J. Sun Y. Han H. Sun Metabonomics and Proteomics Annotate Therapeutic Properties of Geniposide: Targeting and Regulating Multiple Perturbed Pathways PLoS One 2013 8 800 802
19. J. Y. Gao Y. Y. Cheng Application of Metabolomics Technology in Renal Diseases Research Chinese Journal of Integrated Traditional and Western Nephrology 2011 12 466 470
20. X. J. Wang B. Yang A. H. Zhang H. Sun G. Yan Potential drug targets on insomnia and intervention effects of Jujuboside A through metabolic pathway analysis as revealed by UPLC/ESI-SYNAPT-HDMS coupled with pattern recognition approach J. Proteomics 2012 75 1411 1427
21. J. H. Shin J. Y. Yang B. Y. Jeon Y. J. Yoon S. N. Cho Y. H. Kang H. Ryu do G. S. Hwang (1)H NMR-based metabolomic profiling in mice infected with Mycobacterium tuberculosis J. Proteome Res. 2011 10 2238 2247
22. D. M. Wu J. Lu Y. L. Zheng Y. L. Z. Zhou Q. Shan D. F. Ma Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins Neurobiol. Learn. Mem. 2008 90 19 27
23. L. Ming X. Hua X. Ming J. Ding Q. Han H. Gang Impairments of astrocytes are involved in the d-galactose-induced brain aging Biochem. Biophys. Res. Commun. 2008 4 1082 1087
24. M. M. Steed S. C. Tyagi Mechanisms of cardiovascular remodeling in hyperhomocysteinemia Antioxid. Redox Signaling 2011 7 1927 1943
25. M. J. Sarnak A. S. Levey A. C. Schoolwerth J. Coresh B. Culleton L. L. Hamm P. A. McCullough B. L. Kasiske E. Kelepouris M. J. Klag P. Parfrey M. Pfeffer L. Raij D. J. Spinosa P. W. Wilson Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention, Circulation 2003 108 2154 2169
26. A. S. Go G. M. Chertow D. Fan C. E. McCulloch C. Y. Hsu Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization N. Engl. J. Med. 2004 351 1296 1305
27. J. Heinz S. Kropf C. Luley J. Dierkes Homocysteine as a risk factor for cardiovascular disease in patients treated by dialysis, a meta-analysis Am. J. Kidney Dis. 2009 54 478 489
28. L. Chen R. H. Jia C. J. Qiu G. Ding Hyperglycemia inhibits the uptake of dehydroascorbate in tubular epithelial cell Am. J. Nephrol. 2005 5 459 465
29. T. B. Zhou G. P. C. Drummen Y. H. Qin The controversial role of retinoic acid in fibrotic diseases: analysis of involved signaling pathways Int. J. Mol. Sci. 2012 1 226 243
30. R. P. Aguilar S. Genta L. Oliveros A. Anzulovich M. S. Gimenez S. S. Sanchez Vitamin A deficiency injures liver parenchyma and alters the expression of hepatic extracellular matrix J. Appl. Toxicol. 2009 29 214 222
31. T. B. Zhou Y. H. Qin Z. Y. Li H. L. Xu Y. J. Zhao F. Y. Lei All-trans retinoic acid treatment is associated with prohibit in expression in renal interstitial fibrosis rats Int. J. Mol. Sci. 2012 13 2769 2782
32. G. Dixon J. Nolan N. Mcclenaghan P. R. Flatt P. Newsholme A comparative study of amino acid consumption by rat islet cells and the clonal beta-cell line BRIN-BD11-the functional significance of l-alanine, J. Endocrinol. 2003 3 447 454
33. N. H. McClenaghan C. R. Barnett F. P. M. O'Harte P. R. Flatt Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRINBD11 pancreatic β-cell line J. Endocrinol. 1996 15 349 357
34. P. Manna S. K. Jain Phosphatidylinositol-3,4,5-triphosphate and Cellular Signaling: Implications for Obesity and Diabetes Cell. Physiol. Biochem. 2015 35 1253 1275
35. C. Pendaries H. Tronchere M. Plantavid B. Payrastre Phosphoinositide signaling disorders in human diseases FEBS Lett. 2003 546 25 31