Application of GC/MS-based metabonomic profiling in studying the therapeutic effects of Huangbai-Zhimu herb-pair (HZ) extract on streptozotocin-induced type 2 diabetes in mice

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 997, Issue , 2015, Pages 96-104

  Song, Lili ^a   Liu, Hongyue ^a   Wang, Yan ^a   Wang, Yuming ^a   Liu, Jinbiao ^b   Zhou, Zhensheng ^a   Chu, Huilun ^a   Zhuang, Pengwei ^a,c   Zhang, Yanjun ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b TIANJIN UNIVERSITY OF TECHNOLOGY   (China)

^c Tianjin Economic Technological Development Area   (China)

Author keywords

GC MS; Huangbai Zhimu herb pair; Type 2 diabetes; Urine metabonomics

Indexed keywords

BODY FLUIDS; CARBOXYLATION; FATTY ACIDS; GLUCOSE; METABOLISM; PALMITIC ACID; PHYSIOLOGY; PROPIONIC ACID; SATURATED FATTY ACIDS;

3-HYDROXYBUTYRIC ACID; FATTY ACID METABOLISM; GAS CHROMATOGRAPH MASS SPECTROMETERS; GC-MS; HERB PAIRS; METABONOMICS; TYPE 2 DIABETIC MELLITUS; TYPE-2 DIABETES;

MAMMALS;

3 HYDROXYBUTYRIC ACID; ANTIDIABETIC AGENT; CHINESE DRUG; DICARBOXYLIC ACID; GLUCOSE; GLYOXYLIC ACID; HUANGBAI ZHIMU HERB PAIR EXTRACT; PALMITIC ACID; PROPIONIC ACID; STARCH; STEARIC ACID; SUCROSE; UNCLASSIFIED DRUG; FATTY ACID; GLUCOSE BLOOD LEVEL; HERBACEOUS AGENT; HUANGBAI; SAPONIN; STREPTOZOCIN; ZHI-MU SAPONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CALORIE; CONTROLLED STUDY; FATTY ACID METABOLISM; GLUCOSE BLOOD LEVEL; LIPID DIET; MALE; MASS FRAGMENTOGRAPHY; METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; SUCROSE METABOLISM; THERAPY EFFECT; URINE; ANIMAL; C57BL MOUSE; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; METABOLOME; METABOLOMICS; NON INSULIN DEPENDENT DIABETES MELLITUS; PROCEDURES; REPRODUCIBILITY;

MUS;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DRUGS, CHINESE HERBAL; FATTY ACIDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MALE; METABOLOME; METABOLOMICS; MICE; MICE, INBRED C57BL; REPRODUCIBILITY OF RESULTS; SAPONINS; STREPTOZOCIN;

EID: 84934992813     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2015.05.003     Document Type: Article

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