GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures

Alcoholism: Clinical and Experimental Research

Volumn 39, Issue 9, 2015, Pages 1654-1664

  Lieberman, Richard ^a   Kranzler, Henry R ^c,d   Joshi, Pujan ^e   Shin, Dong Guk ^b,e   Covault, Jonathan ^a,b  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e University of Connecticut   (United States)

Author keywords

Alcohol Dependence; GABAA Receptor; GABRA2; Gene Expression; Induced Pluripotent Stem Cells

Indexed keywords

4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; 4 AMINOBUTYRIC ACID A RECEPTOR BETA1; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA1; ALCOHOL; MESSENGER RNA; 4 AMINOBUTYRIC ACID A RECEPTOR; GABRA2 PROTEIN, HUMAN; PROTEIN SUBUNIT;

ADULT; ALCOHOLISM; ALLELE; ARTICLE; AUTOPSY; BRAIN NERVE CELL; CHROMOSOME 4P; CHROMOSOME 4P12; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC RISK; GENOTYPE; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; NERVE CELL DIFFERENTIATION; NEXT GENERATION SEQUENCING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RNA SEQUENCE; ADOLESCENT; AGED; BIOSYNTHESIS; CELL CULTURE; CELL LINE; CHROMOSOME 4; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; NERVE CELL; NEURAL STEM CELL; PHYSIOLOGY; PROTEIN SUBUNIT; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALCOHOLISM; ALLELES; CELL LINE; CELLS, CULTURED; CHROMOSOMES, HUMAN, PAIR 4; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; NEURAL STEM CELLS; NEURONS; PROTEIN SUBUNITS; RECEPTORS, GABA-A; YOUNG ADULT;

EID: 84941168684     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12807     Document Type: Article

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