Protracted Developmental Trajectories of GABAA Receptor α1 and α2 Subunit Expression in Primate Prefrontal Cortex

Biological Psychiatry

Volumn 65, Issue 12, 2009, Pages 1015-1023

  Hashimoto, Takanori ^a,b   Nguyen, Quyen L ^a   Rotaru, Diana ^a   Keenan, Tanya ^a   Arion, Dominique ^a   Beneyto, Monica ^a   Gonzalez Burgos, Guillermo ^a   Lewis, David A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Adolescence; in situ hybridization; mIPSP; schizophrenia; western blot; working memory

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; MESSENGER RNA; UNCLASSIFIED DRUG;

AGE DETERMINATION; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN MATURATION; FEMALE; IN SITU HYBRIDIZATION; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; MONKEY; NEUROTRANSMISSION; NONHUMAN; PATCH CLAMP; POSTNATAL DEVELOPMENT; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SCHIZOPHRENIA; WESTERN BLOTTING; WORKING MEMORY;

ANIMALS; BLOTTING, WESTERN; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; IN SITU HYBRIDIZATION; KINETICS; MACACA MULATTA; MALE; MEMORY, SHORT-TERM; PATCH-CLAMP TECHNIQUES; PREFRONTAL CORTEX; RECEPTORS, GABA-A; RNA PROBES; RNA, MESSENGER; SEXUAL MATURATION;

EID: 67349277163     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2009.01.004     Document Type: Article

References (48)

1. Weinberger D.R., Berman K.F., and Zec R.F. Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Arch Gen Psychiatry 43 (1986) 114-124
2. Goldman-Rakic P.S. Working memory dysfunction in schizophrenia. J Neuropsychiatry Clin Neurosci 6 (1994) 348-357
3. Davidson M., Reichenberg A., Rabinowitz J., Weiser M., Kaplan Z., and Mark M. Behavioral and intellectual markers for schizophrenia in apparently healthy male adolescents. Am J Psychiatry 156 (1999) 1328-1335
4. Saykin A.J., Shtasel D.L., Gur R.E., Kester D.B., Mozley L.H., Stafiniak P., and Gur R.C. Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia. Arch Gen Psychiatry 51 (1994) 124-131
5. Green M.F. Schizophrenia from a Neurocognitive Perspective: Probing the Impenetrable Darkness (1998), Allyn and Bacon, Boston
6. Cosway R., Byrne M., Clafferty R., Hodges A., Grant E., Abukmeil S.S., et al. Neuropsychological change in young people at high risk for schizophrenia: Results from the first two neuropsychological assessments of the Edinburgh High Risk Study. Psychol Med 30 (2000) 1111-1121
7. Lewis D.A., and Lieberman J.A. Catching up on schizophrenia: Natural history and neurobiology. Neuron 28 (2000) 325-334
8. Diamond A. Normal development of prefrontal cortex from birth to young adulthood: Cognitive functions, anatomy and biochemistry. In: Stuss D.T., and Knight R.T. (Eds). Principles of Frontal Lobe Function (2002), Oxford University Press, London 466-503
9. Luna B., Garver K.E., Urban T.A., Lazar N.A., and Sweeney J.A. Maturation of cognitive processes from late childhood to adulthood. Child Devel 75 (2004) 1357-1372
10. Alexander G.E., and Goldman P.S. Functional development of the dorsolateral prefrontal cortex: An analysis utilizing reversible cryogenic depression. Brain Res 143 (1978) 233-249
11. Alexander G.E. Functional development of frontal association cortex in monkeys: Behavioral and electrophysiological studies. Neurosciences Res Prog Bull 20 (1982) 471-479
12. Crone E.A., Wendelken C., Donohue S., van Leijenhorst L., and Bunge S.A. Neurocognitive development of the ability to manipulate information in working memory. Proc Natl Acad Sci U S A 103 (2006) 9315-9320
13. Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 44 (1987) 660-669
14. Lewis D.A., and Levitt P. Schizophrenia as a disorder of neurodevelopment. Ann Rev Neurosci 25 (2002) 409-432
15. Lewis D.A., Hashimoto T., and Volk D.W. Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci 6 (2005) 312-324
16. Akbarian S., Kim J.J., Potkin S.G., Hagman J.O., Tafazzoli A., Bunney Jr. W.E., and Jones E.G. Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch Gen Psychiatry 52 (1995) 258-266
17. Volk D.W., Austin M.C., Pierri J.N., Sampson A.R., and Lewis D.A. Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia. Arch Gen Psychiatry 57 (2000) 237-245
18. 67) expression in schizophrenia and bipolar disorder. Arch Gen Psychiatry 57 (2000) 1061-1069
19. Hashimoto T., Bergen S.E., Nguyen Q.L., Xu B., Monteggia L.M., Pierri J.N., et al. Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. J Neurosci 25 (2005) 372-383
20. Hashimoto T., Arion D., Unger T., Maldonado-Aviles J.G., Morris H.M., Volk D.W., et al. Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia. Mol Psychiatry 13 (2008) 147-161
21. Straub R.E., Lipska B.K., Egan M.F., Goldberg T.E., Callicott J.H., Mayhew M.B., et al. Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. Mol Psychiatry 12 (2007) 854-869
22. Mohler H. GABA(A) receptor diversity and pharmacology. Cell Tissue Res 326 (2006) 505-516
23. Volk D.W., Pierri J.N., Fritschy J.-M., Auh S., Sampson A.R., and Lewis D.A. Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia. Cereb Cortex 12 (2002) 1063-1070
24. Fritschy J.-M., Paysan J., Enna A., and Mohler H. Switch in the expression of rat GABAA-receptor subtypes during postnatal development: An immunohistochemical study. J Neurosci 14 (1994) 5302-5324
25. Farrant M., and Nusser Z. Variations on an inhibitory theme: Phasic and tonic activation of GABA(A) receptors. Nat Rev Neurosci 6 (2005) 215-229
26. Hollrigel G.S., and Soltesz I. Slow kinetics of miniature IPSCs during early postnatal development in granule cells of the dentate gyrus. J Neurosci 17 (1997) 5119-5128
27. A blockade of prefrontal cortical neurons engaged by working memory. J Neurosci 20 (2000) 485-494
28. Sawaguchi T., Matsumura M., and Kubota K. Delayed response deficits produced by local injection of bicuculline into the dorsolateral prefrontal cortex in Japanese macaque monkeys. Exp Brain Res 75 (1989) 457-469
29. Cruz D.A., Eggan S.M., and Lewis D.A. Postnatal development of pre- and post-synaptic GABA markers at chandelier cell inputs to pyramidal neurons in monkey prefrontal cortex. J Comp Neurol 465 (2003) 385-400
30. Gonzalez-Burgos G., Kroener S., Zaitsev A.V., Povysheva N.V., Krimer L.S., Barrionuevo G., and Lewis D.A. Functional maturation of excitatory synapses in layer 3 pyramidal neurons during postnatal development of the primate prefrontal cortex. Cereb Cortex 18 (2008) 626-637
31. Weiland N.G., and Orchinik M. Specific subunit mRNAs of the GABAA receptor are regulated by progesterone in subfields of the hippocampus. Brain Res Mol Brain Res 32 (1995) 271-278
32. Biggio G., Follesa P., Sanna E., Purdy R.H., and Concas A. GABAA-receptor plasticity during long-term exposure to and withdrawal from progesterone. Int Rev Neurobiol 46 (2001) 207-241
33. Kralic J.E., Korpi E.R., O'Buckley T.K., Homanics G.E., and Morrow A.L. Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice. J Pharmacol Exp Ther 302 (2002) 1037-1045
34. Laurie D.J., Wisden W., and Seeburg P.H. The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development. J Neurosci 12 (1992) 4151-4172
35. Hornung J.-P., and Fritschy J.-M. Developmental profile of GABAA-receptors in the marmoset monkey: Expression of distinct subtypes in pre- and postnatal brain. J Comp Neurol. 367 (1996) 413-430
36. Kanaumi T., Takashima S., Iwasaki H., Mitsudome A., and Hirose S. Developmental changes in the expression of GABAA receptor alpha 1 and gamma 2 subunits in human temporal lobe, hippocampus and basal ganglia: An implication for consideration on age-related epilepsy. Epilepsy Res 71 (2006) 47-53
37. Houston C.M., Hosie A.M., and Smart T.G. Distinct regulation of beta2 and beta3 subunit-containing cerebellar synaptic GABAA receptors by calcium/calmodulin-dependent protein kinase II. J Neurosci 28 (2008) 7574-7584
38. Nusser Z., Sieghart W., Benke D., Fritschy J.-M., and Somogyi P. Differential synaptic localization of two major γ-aminobutyric acid type A receptor α subunits on hippocampal pyramidal cells. Proc Natl Acad Sci U S A 93 (1996) 11939-11944
39. A-receptor heterogeneity in the adult rat brain: Differential regional and cellular distribution of seven major subunits. J Comp Neurol 359 (1995) 154-194
40. Areceptors in the hippocampus. J Neurosci 22 (2002) 2513-2521
41. 2 subunit-containing GABAA receptors in synapses of hippocampal pyramidal cells of the rat. Eur J Neurosci 13 (2001) 428-442
42. Katagiri H., Fagiolini M., and Hensch T.K. Optimization of somatic inhibition at critical period onset in mouse visual cortex. Neuron 53 (2007) 805-812
43. Kisvarday Z.F., Beaulieu C., and Eysel U.T. Network of GABAergic large basket cells in cat visual cortex (Area 18): Implication for lateral disinhibition. J Comp Neurol. 327 (1993) 398-415
44. Bartos M., Vida I., and Jonas P. Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks. Nat Rev Neurosci 8 (2007) 45-56
45. Jensen O., Kaiser J., and Lachauz J.P. Human gamma-frequency oscillations associated with attention and memory. Trends Neurosci 30 (2007) 317-324
46. Uhlhaas P.J., Roux F., Singer W., Haenschel C., Sireteanu R., and Rodriguez E. Development of task-related neural synchrony reflects maturation and restructuring of cortical networks in humans. Soc Neuroscience Online Abstract 791 (2007) 11
47. Benes F.M., Vincent S.L., Marie A., and Khan Y. Up-regulation of GABA-A receptor binding on neurons of the prefrontal cortex in schizophrenic subjects. Neuroscience 75 (1996) 1021-1031
48. Lewis D.A., and Gonzalez-Burgos G. Neuroplasticity of neocortical circuits in schizophrenia. Neuropsychopharmacol Rev 33 (2008) 141-165