Herbal medicine-related hepatotoxicity

World Journal of Hepatology

Volumn 7, Issue 19, 2015, Pages 2189-2193

  Stournaras, Evangelos ^a   Tziomalos, Konstantinos ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Cholestasis; Herbal medicines; Liver transplantation

Indexed keywords

EID: 84941134122     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v7.i19.2189     Document Type: Editorial

References (37)

1. De Smet PA. Herbal medicine in Europe-relaxing regulatory standards. N Engl J Med 2005; 352: 1176-1178 [PMID: 15788494 DOI: 10.1056/NEJMp048083]
2. Garcia-Alvarez A, Egan B, de Klein S, Dima L, Maggi FM, Isoniemi M, Ribas-Barba L, Raats MM, Meissner EM, Badea M, Bruno F, Salmenhaara M, Milà-Villarroel R, Knaze V, Hodgkins C, Marculescu A, Uusitalo L, Restani P, Serra-Majem L. Usage of plant food supplements across six European countries: findings from the PlantLIBRA consumer survey. PLoS One 2014; 9: e92265 [PMID: 24642692 DOI: 10.1371/journal.pone.0092265]
3. Cohen PA. Assessing supplement safety--the FDA's controversial proposal. N Engl J Med 2012; 366: 389-391 [PMID: 22276780 DOI: 10.1056/NEJMp1113325]
4. Radimer K, Bindewald B, Hughes J, Ervin B, Swanson C, Picciano MF. Dietary supplement use by US adults: data from the National Health and Nutrition Examination Survey, 1999-2000. Am J Epidemiol 2004; 160: 339-349 [PMID: 15286019 DOI: 10.1093/ aje/kwh207]
5. US Food and Drug Administration. Dietary Supplement Health and Education Act of 1994. [accessed 2015 May 10]. Available from: URL: http://www.gpo.gov/fdsys/pkg/BILLS-103s784es/pdf/ BILLS-103s784es.pdf
6. US Food and Drug Administration. Dietary Supplements. [accessed 2015 May 10]. Available from: URL: http: //www. fda.gov/Food/DietarySupplements/QADietarySupplements/ ucm191930.htm
7. Seeff LB, Bonkovsky HL, Navarro VJ, Wang G. Herbal products and the liver: a review of adverse effects and mechanisms. Gastroenterology 2015; 148: 517-532.e3 [PMID: 25500423 DOI: 10.1053/j.gastro.2014.12.004]
8. Saper RB, Phillips RS, Sehgal A, Khouri N, Davis RB, Paquin J, Thuppil V, Kales SN. Lead, mercury, and arsenic in US- and Indian-manufactured Ayurvedic medicines sold via the Internet. JAMA 2008; 300: 915-923 [PMID: 18728265 DOI: 10.1001/ jama.300.8.915]
9. Stickel F, Droz S, Patsenker E, Bögli-Stuber K, Aebi B, Leib SL. Severe hepatotoxicity following ingestion of Herbalife nutritional supplements contaminated with Bacillus subtilis. J Hepatol 2009; 50: 111-117 [PMID: 19010564 DOI: 10.1016/j.jhep.2008.08.017]
10. Ernst E. Adulteration of Chinese herbal medicines with synthetic drugs: a systematic review. J Intern Med 2002; 252: 107-113 [PMID: 12190885 DOI: 10.1046/j.1365-2796.2002.00999.x]
11. Björnsson ES, Bergmann OM, Björnsson HK, Kvaran RB, Olafsson S. Incidence, presentation, and outcomes in patients with drug-induced liver injury in the general population of Iceland. Gastroenterology 2013; 144: 1419-1425, 1425.e1-e3; quiz e19-e20 [PMID: 23419359 DOI: 10.1053/j.gastro.2013.02.006]
12. Navarro VJ, Barnhart H, Bonkovsky HL, Davern T, Fontana RJ, Grant L, Reddy KR, Seeff LB, Serrano J, Sherker AH, Stolz A, Talwalkar J, Vega M, Vuppalanchi R. Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network. Hepatology 2014; 60: 1399-1408 [PMID: 25043597 DOI: 10.1002/hep.27317]
13. Rossi S, Navarro VJ. Herbs and liver injury: a clinical perspective. Clin Gastroenterol Hepatol 2014; 12: 1069-1076 [PMID: 23924877 DOI: 10.1016/j.cgh.2013.07.030]
14. Goldberg DS, Forde KA, Carbonari DM, Lewis JD, Leidl KB, Reddy KR, Haynes K, Roy J, Sha D, Marks AR, Schneider JL, Strom BL, Corley DA, Lo Re V. Population-representative incidence of drug-induced acute liver failure based on an analysis of an integrated health care system. Gastroenterology 2015; 148: 1353-1361.e3 [PMID: 25733099 DOI: 10.1053/j. gastro.2015.02.050]
15. Andrade RJ, Lucena MI, Fernández MC, Pelaez G, Pachkoria K, García-Ruiz E, García-Muñoz B, González-Grande R, Pizarro A, Durán JA, Jiménez M, Rodrigo L, Romero-Gomez M, Navarro JM, Planas R, Costa J, Borras A, Soler A, Salmerón J, Martin-Vivaldi R. Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period. Gastroenterology 2005; 129: 512-521 [PMID: 16083708 DOI: 10.1053/j. gastro.2005.05.006]
16. Suk KT, Kim DJ, Kim CH, Park SH, Yoon JH, Kim YS, Baik GH, Kim JB, Kweon YO, Kim BI, Kim SH, Kim IH, Kim JH, Nam SW, Paik YH, Suh JI, Sohn JH, Ahn BM, Um SH, Lee HJ, Cho M, Jang MK, Choi SK, Hwang SG, Sung HT, Choi JY, Han KH. A prospective nationwide study of drug-induced liver injury in Korea. Am J Gastroenterol 2012; 107: 1380-1387 [PMID: 22733303 DOI: 10.1038/ajg.2012.138]
17. Chalasani NP, Hayashi PH, Bonkovsky HL, Navarro VJ, Lee WM, Fontana RJ. ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury. Am J Gastroenterol 2014; 109: 950-966; quiz 967 [PMID: 24935270 DOI: 10.1038/ajg.2014.131]
18. Timcheh-Hariri A, Balali-Mood M, Aryan E, Sadeghi M, Riahi-Zanjani B. Toxic hepatitis in a group of 20 male body-builders taking dietary supplements. Food Chem Toxicol 2012; 50: 3826-3832 [PMID: 22809474 DOI: 10.1016/j.fct.2012.07.006]
19. Benninger J, Schneider HT, Schuppan D, Kirchner T, Hahn EG. Acute hepatitis induced by greater celandine (Chelidonium majus). Gastroenterology 1999; 117: 1234-1237 [PMID: 10535888 DOI: 10.1016/S0016-5085(99)70410-5]
20. Nadir A, Reddy D, Van Thiel DH. Cascara sagrada-induced intrahepatic cholestasis causing portal hypertension: case report and review of herbal hepatotoxicity. Am J Gastroenterol 2000; 95: 3634-3637 [PMID: 11151906 DOI: 10.1016/S0002-9270(00)02179-1]
21. Fong TL, Klontz KC, Canas-Coto A, Casper SJ, Durazo FA, Davern TJ, Hayashi P, Lee WM, Seeff LB. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol 2010; 105: 1561-1566 [PMID: 20104221 DOI: 10.1038/ajg.2010.5]
22. Roytman MM, Pörzgen P, Lee CL, Huddleston L, Kuo TT, Bryant-Greenwood P, Wong LL, Tsai N. Outbreak of severe hepatitis linked to weight-loss supplement OxyELITE Pro. Am J Gastroenterol 2014; 109: 1296-1298 [PMID: 25091255 DOI: 10.1038/ajg.2014.159]
23. Schoepfer AM, Engel A, Fattinger K, Marbet UA, Criblez D, Reichen J, Zimmermann A, Oneta CM. Herbal does not mean innocuous: ten cases of severe hepatotoxicity associated with dietary supplements from Herbalife products. J Hepatol 2007; 47: 521-526 [PMID: 17692989 DOI: 10.1016/j.jhep.2007.06.014]
24. Fau D, Lekehal M, Farrell G, Moreau A, Moulis C, Feldmann G, Haouzi D, Pessayre D. Diterpenoids from germander, an herbal medicine, induce apoptosis in isolated rat hepatocytes. Gastroenterology 1997; 113: 1334-1346 [PMID: 9322529 DOI: 10.1053/ gast.1997.v113.pm9322529]
25. Lambert JD, Kennett MJ, Sang S, Reuhl KR, Ju J, Yang CS. Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice. Food Chem Toxicol 2010; 48: 409-416 [PMID: 19883714 DOI: 10.1016/j.fct.2009.10.030]
26. Mazzanti G, Menniti-Ippolito F, Moro PA, Cassetti F, Raschetti R, Santuccio C, Mastrangelo S. Hepatotoxicity from green tea: a review of the literature and two unpublished cases. Eur J Clin Pharmacol 2009; 65: 331-341 [PMID: 19198822 DOI: 10.1007/ s00228-008-0610-7]
27. Weston CF, Cooper BT, Davies JD, Levine DF. Veno-occlusive disease of the liver secondary to ingestion of comfrey. Br Med J (Clin Res Ed) 1987; 295: 183 [PMID: 3115370 DOI: 10.1136/bmj. 295.6591.183]
28. Russmann S, Lauterburg BH, Helbling A. Kava hepatotoxicity. Ann Intern Med 2001; 135: 68-69 [PMID: 11434754 DOI: 10.7326 /0003-4819-135-1-200107030-00036]
29. Lynch CR, Folkers ME, Hutson WR. Fulminant hepatic failure associated with the use of black cohosh: a case report. Liver Transpl 2006; 12: 989-992 [PMID: 16721764 DOI: 10.1002/lt. 20778]
30. Levitsky J, Alli TA, Wisecarver J, Sorrell MF. Fulminant liver failure associated with the use of black cohosh. Dig Dis Sci 2005; 50: 538-539 [PMID: 15810638 DOI: 10.1007/s10620-005-2470-7]
31. Ebrahim V, Albeldawi M, Chiang DJ. Acute liver injury associated with glucosamine dietary supplement. BMJ Case Rep 2012; 2012: pii: bcr2012007665 [PMID: 23239775 DOI: 10.1136/ bcr-2012-007665]
32. Blendon RJ, DesRoches CM, Benson JM, Brodie M, Altman DE. Americans' views on the use and regulation of dietary supplements. Arch Intern Med 2001; 161: 805-810 [PMID: 11268222 DOI: 10.1001/archinte.161.6.805]
33. Navarro VJ, Senior JR. Drug-related hepatotoxicity. N Engl J Med 2006; 354: 731-739 [PMID: 16481640 DOI: 10.1056/ NEJMra052270]
34. Roussel Uclaf Causality Assessment Method (RUCAM) in Drug Induced Liver Injury. [Accessed 2015 May 10]. Available from: URL: http://www.livertox.nih.gov/rucam.html
35. Chalasani N, Bonkovsky HL, Fontana R, Lee W, Stolz A, Talwalkar J, Reddy KR, Watkins PB, Navarro V, Barnhart H, Gu J, Serrano J. Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study. Gastroenterology 2015; 148: 1340-1352.e7 [PMID: 25754159 DOI: 10.1053/j.gastro.2015.03.006]
36. Rockey DC, Seeff LB, Rochon J, Freston J, Chalasani N, Bonacini M, Fontana RJ, Hayashi PH. Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method. Hepatology 2010; 51: 2117-2126 [PMID: 20512999 DOI: 10.1002/hep.23577]
37. Navarro VJ, Barnhart HX, Bonkovsky HL, Reddy KR, Seeff L, Serrano J, Talwalkar J, Vega M, Vuppalanchi R. 1364 Diagnosing Hepatotoxicity Attributable To Herbal & Dietary Supplements (HDS): Test-Retest Reliability of a Novel Causality Assessment Tool. J Hepatol 2012; 56: S536 [DOI: 10.1016/S0168- 8278(12)61 375-0]