Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network

Hepatology

Volumn 60, Issue 4, 2014, Pages 1399-1408

  Navarro, Victor J ^a   Barnhart, Huiman ^b   Bonkovsky, Herbert L ^c   Davern, Timothy ^d   Fontana, Robert J ^e   Grant, Lafaine ^f   Reddy, K Rajender ^g   Seeff, Leonard B ^a   Serrano, Jose ^h   Sherker, Averell H ^h   Stolz, Andrew ⁱ   Talwalkar, Jayant ^j   Vega, Maricruz ^a   Vuppalanchi, Raj ^k  

^a EINSTEIN MEDICAL CENTER   (United States)

^b DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^c LEVINE CANCER INSTITUTE   (United States)

^d CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

ⁱ UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^j MAYO CLINIC   (United States)

^k INDIANA UNIVERSITY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; DIET SUPPLEMENTATION; DIFFERENTIAL DIAGNOSIS; FEMALE; HERBAL MEDICINE; HOSPITALIZATION; HUMAN; JAUNDICE; LIVER CELL DAMAGE; LIVER INJURY; LIVER TOXICITY; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRACTICE GUIDELINE; PRIORITY JOURNAL; TOXIC HEPATITIS; UNITED STATES; ADVERSE EFFECTS; AGED; DIETARY SUPPLEMENT; DRUG-INDUCED LIVER INJURY; INCIDENCE; MIDDLE AGED; MORTALITY; PROSPECTIVE STUDY; RETROSPECTIVE STUDY;

HERBACEOUS AGENT;

ADULT; AGED; DIETARY SUPPLEMENTS; DRUG-INDUCED LIVER INJURY; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; INCIDENCE; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; UNITED STATES;

EID: 84926447989     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27317     Document Type: Article

References (37)

1. Bailey RL, Gahche JJ, Lentino CV, Dwyer JT, Engel JS, Thomas PR, et al. Dietary supplement use in the United States, 2003-2006. J Nutr 2011;141:261-266.
2. Picciano MF, Dwyer JT, Radimer KL, Wilson DH, Fisher KD, Thomas PR, et al. Dietary supplement use among infants, children, and adolescents in the United States, 1999-2002. Arch Pediatr Adolesc Med 2007;161:978-985.
3. Radimer K, Bindewald B, Hughes J, Ervin B, Swanson C, Picciano MF. Dietary supplement use by US adults: data from the National Health and Nutrition Examination Survey, 1999-2000. Am J Epidemiol 2004;160:339-349.
4. Bailey, RL, Gahche JJ, Miller PE, Thomas PR, Dwyer JT. Why US adults use dietary supplements. JAMA Intern Med 2013;173:355-361.
5. Foote JA, Murphy SP, Wilkens LR, Hankin JH, Henderson BE, Kolonel LN. Factors associated with dietary supplement use among healthy adults of five ethnicities: the Multiethnic Cohort Study. Am J Epidemiol 2003;157:888-897.
6. Block G, Jensen CD, Norkus EP, Dalvi TB, Wong LG, McManus JF, Hudes ML. Usage patterns, health, and nutritional status of long-term multiple dietary supplement users: a cross-sectional study. Nutr J 2007;6:30.
7. Snyder FJ, Dundas ML, Kirkpatrick C, Neill KS. Use and safety perceptions regarding herbal supplements: a study of older persons in southeast Idaho. J Nutr Elder 2009;28:81-95.
8. U.S. Food and Drug Administration. Dietary supplements. Available at: http://www.fda.gov/Food/DietarySupplements/default.htm. Accessed May 7, 2013.
9. U.S. Food and Drug Administration. FDA investigates acute hepatitis illnesses potentially linked to products labeled OxyElite Pro. Available at: http://www.fda.gov/Food/RecallsOutbreaksEmergencies/Outbreaks/ucm370849.htm. Accessed November 16, 2013.
10. Fontana RJ, Watkins PB, Bonkovsky HL, Chalasani N, Davern T, Serrano J, Rochon J; DILIN Study Group. Rationale, design and conduct of the Drug Induced Liver Injury Network prospective study. Drug Saf 2009;32:55-68.
11. Chalasani N, Fontana RJ, Bonkovsky HL, Watkins PB, Davern T, Serrano J, et al.; Drug Induced Liver Injury Network (DILIN). Causes, clinical features, and outcomes from a prospective study of drug induced liver injury in the United States. Gastroenterology 2008;135:1924-1934, 1934.e1-4.
12. Danan G, Benichou C. Causality assessment of adverse reactions to drugs-I. A novel method based on the conclusions of international consensus meetings; application to drug-induced liver injuries. J Clin Epidemiol 1993;46:1323-1330.
13. Andrade RJ, Lucena MI, Fernández MC, Pelaez G, Pachkoria K, García-Ruiz E, et al.; Spanish Group for the Study of Drug-Induced Liver Disease. Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10 year period. Gastroenterology 2005;129:512-521.
14. Bjornsson E, Bergman OM, Bjornsson HK, Kyaran RB, Olafsson S. Incidence, presentation, and outcomes in patients with drug-induced liver injury in the general population of Iceland. Gastroenterology 2013;144:1419-1425.
15. Eisenberg DM, Kessler RC, Foster C, Norlock FE, Calkins DR, Delbanco TL. Unconventional medicine in the United States: prevalence, costs, and patterns of use. NEJM 1993;328:246-252.
16. Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, Van Rompay M, Kessler RC. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national study. JAMA 1998;280:1569-1575.
17. Ervin RB, Wright JD, Kennedy-Stephenson J. Use of dietary supplements in the United States, 1988-1994. Vital Health Stat 1999;11:i-iii, 1-14.
18. Nahin RL, Barnes PM, Stussman BJ, Bloom B. Costs of complementary and alternative medicine (CAM) and frequency of visits to CAM practitioners: United States, 2007. National health statistics reports; no. 18. Hyattsville, MD: National Center for Health Statistics, 2009.
19. Lindstrom A, Ooyen C, Lynch ME, Blumenthal M. Herb supplement sales increase 5.5% in 2012: herbal supplement sales rise for the 9th consecutive year: turmeric sales jump 40% in herbal channel. HerbalGram 2013;99:60-65.
20. Martin DJ, Partridge BJ, Shields W. Hepatotoxicity associated with the dietary supplement N.O.-XPLODE. Ann Int Med 2013:159:7:503-504.
21. Ishak KG, Hepatic lesions caused by anabolic and contraceptive steroids. Semin Liver Dis 1981;1:116-128.
22. Singh V, Rudraraju M, Carey EJ, Byrne TJ, Vargas HE, Williams JE, et al. Severe hepatotoxicity caused by a Methasteron-containing performance-enhancing supplement. J Clin Gastroenterol 2009;43:287.
23. Timchec-Hariri A, Balali-Mood M, Aryan E, Sadeghi M, Riahi-Zanjani B. Toxic hepatitis in a group of 20 male body-builders taking dietary supplements. Food Chem Toixicol 2012;50:3826-3832.
24. Buttner A. Thieme D. Side effects of anabolic androgenic steroids: pathological findings and structure-activity relationships. Handb Exp Pharmacol 2010;195:459-484.
25. Urban TJ, Shen Y, Stolz A, Chalasani N, Fontana RJ, Rochon J, et.al.; Drug-Induced Liver Injury Network; DILIGEN; EUDRAGENE; Spanish DILI Registry; International Serious Adverse Events Consortium. Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics 2012;22:784-795.
26. Lucena MI, Molokhia M, Shen Y, Urban TJ, Aithal GP, Andrade RJ, et al.; Spanish DILI Registry; EUDRAGENE; DILIN; DILIGEN; International SAEC. Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology 2011;141:338-347.
27. Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A, et al.; Shen Y, Pe'er I, Floratos A, HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat Genet 2009;41:816-819.
28. Kneifel W, Czech E, Kopp B. Microbial contamination of medicinal plants. Planta Med 2000;68:5-15.
29. Stickel F, Droz S, Patsenker E, Bogli-Stuber K, Aebi B, Leib SL. Severe hepatotoxicity following ingestion of Herbalife contaminated with Bacillus subtilis. J Hepatol 2009;50:111-117.
30. Miller GM, Streipp R. A study of western pharmaceuticals contained within samples of Chinese herbal/patent medicines collected from New York City's Chinatown. Leg Med (Tokyo) 2007;9:258-264.
31. Guns ES, Goldenberg SL, Brown PN. Mass spectral analysis of PC-SPES confirms the presence of diethylstilbestrol. Can J Urol 2002;9:1684-1688.
32. Oh WK, Small EJ. Complementary and alternative therapies in prostate cancer. Semin Oncol 2002;29:575-584.
33. Gray SL, Lackey BR, Tate PL, Riley MB, Camper ND. Mycotoxins in root extracts of American and Asian ginseng bind estrogen receptors alpha and beta. Exp Biol Med 2004;229:560-568.
34. Saper RB, Phillips RS, Sehgal A, Khouri N, Davis RB, Paquin J. Lead, mercury, and arsenic in US- and Indian-manufactured Ayurvedic medicines sold via the internet. JAMA 2008;300:915-923.
35. Wong MK, Tan P, Wee YC. Heavy metals in some Chinese herbal plants. Biol Trace Elem 1993;36:135-142.
36. Koh HL, Woo SO. Chinese propriety medicine in Singapore: regulatory control of toxic heavy metals and undeclared drugs. Drug Saf 2000;23:351-362.
37. Au AM, Ko R, Boo FO, Hsu R, Perez G, Yang Z. Screening methods for drugs and heavy metals in Chinese patent medicines. Bull Environ Contam Toxicol 2000;65:112-119.