메뉴 건너뛰기




Volumn 157, Issue 4, 2015, Pages 217-224

The peroxidase activity of bleomycin-Fe3+ is associated with damage to biological components

Author keywords

bleomycin Fe3+; compound I like species; hydroxyl radical; lipid hydroperoxide; peroxidase

Indexed keywords

ALCOHOL DEHYDROGENASE; BLEOMYCIN IRON; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LIPID HYDROPEROXIDE; PEROXIDASE; TETRAMETHYLBENZIDINE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; BENZIDINE DERIVATIVE; BLEOMYCIN; FERRIC ION; N,N,N',N'-TETRAMETHYLBENZIDINE;

EID: 84941132476     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvu063     Document Type: Article
Times cited : (5)

References (34)
  • 3
    • 0017094368 scopus 로고
    • A role for ferrous ion and oxygen in the degradation of DNA by bleomycin
    • Sausville, E.A., Peisach, J., and Horwitz, S.B. (1966) A role for ferrous ion and oxygen in the degradation of DNA by bleomycin. Biochem. Biophys. Res. Commun. 73, 814-822
    • (1966) Biochem. Biophys. Res. Commun. , vol.73 , pp. 814-822
    • Sausville, E.A.1    Peisach, J.2    Horwitz, S.B.3
  • 4
    • 0018149642 scopus 로고
    • Properties and products of the degradation of DNA by bleomycin and iron(II)
    • Sausville, E.A., Stein, R.E., Peisach, J., and Horwitz, S.B. (1966) Properties and products of the degradation of DNA by bleomycin and iron(II). Biochemistry 17, 2746-2754
    • (1966) Biochemistry , vol.17 , pp. 2746-2754
    • Sausville, E.A.1    Stein, R.E.2    Peisach, J.3    Horwitz, S.B.4
  • 5
    • 0019888660 scopus 로고
    • Activated bleomycin,A transient complex of drug, iron, and oxygen that degrades DNA
    • Burger, R.M., Peisach, J., and Horwitz, S.B. (1981) Activated bleomycin. A transient complex of drug, iron, and oxygen that degrades DNA. J. Biol. Chem. 256, 11636-11644
    • (1981) J. Biol. Chem. , vol.256 , pp. 11636-11644
    • Burger, R.M.1    Peisach, J.2    Horwitz, S.B.3
  • 6
    • 0025250121 scopus 로고
    • The role of redox-active metals in the mechanism of action of bleomycin
    • Petering, D.H., Byrnes, R.W., and Antholine, W.E. (1990) The role of redox-active metals in the mechanism of action of bleomycin. Chem. Biol. Interact. 73, 133-182
    • (1990) Chem. Biol. Interact , vol.73 , pp. 133-182
    • Petering, D.H.1    Byrnes, R.W.2    Antholine, W.E.3
  • 7
    • 0026793909 scopus 로고
    • Ascorbate both activates and inactivates bleomycin by free radical generation
    • Buettner, G.R. and Moseley, P.L. (1992) Ascorbate both activates and inactivates bleomycin by free radical generation. Biochemistry 31, 9784-9788
    • (1992) Biochemistry , vol.31 , pp. 9784-9788
    • Buettner, G.R.1    Moseley, P.L.2
  • 8
    • 0015609611 scopus 로고
    • A clinical review of bleomycin-a new antineoplastic agent
    • Blum, R.H., Carter, S.K., and Agre, A. (1973) A clinical review of bleomycin-a new antineoplastic agent. Cancer 31, 903-914
    • (1973) Cancer , vol.31 , pp. 903-914
    • Blum, R.H.1    Carter, S.K.2    Agre, A.3
  • 9
    • 0002746148 scopus 로고    scopus 로고
    • Bleomycins: A structural model for specificity, binding, and double strand cleavage
    • Stubbe, J., Kozarich, J.W., Wu, W., and Vanderwall, D.E. (1996) Bleomycins: a structural model for specificity, binding, and double strand cleavage. Acc. Chem. Res. 29, 322-330
    • (1996) Acc. Chem. Res. , vol.29 , pp. 322-330
    • Stubbe, J.1    Kozarich, J.W.2    Wu, W.3    Vanderwall, D.E.4
  • 10
    • 33748719327 scopus 로고
    • Mechanisms of bleomycin-induced DNA degradation
    • Stubbe, J. and Kozarich, J.W. (1987) Mechanisms of bleomycin-induced DNA degradation. Chem. Rev. 87, 1107-1136
    • (1987) Chem. Rev. , vol.87 , pp. 1107-1136
    • Stubbe, J.1    Kozarich, J.W.2
  • 11
    • 0000357885 scopus 로고    scopus 로고
    • Nucleic acid recognition by metal complexes of bleomycin
    • Claussen, C.A. and Long, E.C. (1999) Nucleic acid recognition by metal complexes of bleomycin. Chem. Rev. 99, 2797-2816
    • (1999) Chem. Rev. , vol.99 , pp. 2797-2816
    • Claussen, C.A.1    Long, E.C.2
  • 12
    • 1842426944 scopus 로고    scopus 로고
    • Bleomycins: New methods will allow reinvestigation of old issues
    • Chen, J. and Stubbe, J. (2004) Bleomycins: new methods will allow reinvestigation of old issues. Curr. Opin. Chem. Biol. 8, 175-181
    • (2004) Curr. Opin. Chem. Biol. , vol.8 , pp. 175-181
    • Chen, J.1    Stubbe, J.2
  • 13
    • 0020645721 scopus 로고
    • Moessbauer study of iron bleomycin and its activation intermediates
    • Burger, R.M., Kent, T.A., Horwitz, S.B., Muenck, E., and Peisach, J. (1983) Moessbauer study of iron bleomycin and its activation intermediates. J. Biol. Chem. 258, 1559-1564
    • (1983) J. Biol. Chem. , vol.258 , pp. 1559-1564
    • Burger, R.M.1    Kent, T.A.2    Horwitz, S.B.3    Muenck, E.4    Peisach, J.5
  • 14
    • 0034731019 scopus 로고    scopus 로고
    • Electronic structure of activated bleomycin, oxygen intermediates in heme versus non-heme iron
    • Neese, F., Zaleski, J.M., Zaleski, K.L., and Solomon, E.I. (2000) Electronic structure of activated bleomycin, oxygen intermediates in heme versus non-heme iron. J. Am. Chem. Soc. 122, 11703-11724
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 11703-11724
    • Neese, F.1    Zaleski, J.M.2    Zaleski, K.L.3    Solomon, E.I.4
  • 15
    • 0029920863 scopus 로고    scopus 로고
    • Measurement of hydroxyl radicals catalyzed in the immediate vicinity of DNA by metal-bleomycin complexes
    • Chakrabarti, S., Makrigiorgos, G.M., O'Brien, K., Bump, E., and Kassis, A.I. (1996) Measurement of hydroxyl radicals catalyzed in the immediate vicinity of DNA by metal-bleomycin complexes. Free Radic. Biol. Med. 20, 777-783
    • (1996) Free Radic. Biol. Med. , vol.20 , pp. 777-783
    • Chakrabarti, S.1    Makrigiorgos, G.M.2    O'Brien, K.3    Bump, E.4    Kassis, A.I.5
  • 16
    • 0023215796 scopus 로고
    • Oxygen radical formation and DNA damage due to enzymic reduction of bleomycin-iron(III)
    • Mahmutoglu, I., Scheulen, M.E., and Kappus, H. (1987) Oxygen radical formation and DNA damage due to enzymic reduction of bleomycin-iron(III). Arch. Toxicol. 60, 150-153
    • (1987) Arch. Toxicol. , vol.60 , pp. 150-153
    • Mahmutoglu, I.1    Scheulen, M.E.2    Kappus, H.3
  • 17
    • 0020058095 scopus 로고
    • Effect of DNA on the production of reduced oxygen by bleomycin and iron
    • Caspary, W.J., Lanzo, D.A., and Niziak, C. (1982) Effect of DNA on the production of reduced oxygen by bleomycin and iron. Biochemistry 21, 334-338
    • (1982) Biochemistry , vol.21 , pp. 334-338
    • Caspary, W.J.1    Lanzo, D.A.2    Niziak, C.3
  • 18
    • 0023213728 scopus 로고
    • ESR studies on the active intermediate in the enzymatic reduction of the iron-bleomycin complex
    • Tero-Kubota, S., Ikegami, Y., Sugioka, K., and Nakano, M. (1987) ESR studies on the active intermediate in the enzymatic reduction of the iron-bleomycin complex. Biochem. Int. 14, 879-887
    • (1987) Biochem. Int. , vol.14 , pp. 879-887
    • Tero-Kubota, S.1    Ikegami, Y.2    Sugioka, K.3    Nakano, M.4
  • 19
    • 0025767788 scopus 로고
    • Bleomycin-dependent damage to the bases in DNA is minor side reaction
    • Gajewski, E., Aruoma, O.I., Dizdaroglu, M., and Halliwell, B. (1991) Bleomycin-dependent damage to the bases in DNA is minor side reaction. Biochemistry 30, 2444-2448
    • (1991) Biochemistry , vol.30 , pp. 2444-2448
    • Gajewski, E.1    Aruoma, O.I.2    Dizdaroglu, M.3    Halliwell, B.4
  • 20
    • 0020055877 scopus 로고
    • Iron(II)-bleomycin,biochemical and spectral properties in the presence of radical scavengers
    • Rodriguez, L.O. and Hecht, O.S. (1982) Iron(II)-bleomycin. Biochemical and spectral properties in the presence of radical scavengers. Biochem. Biophys. Res. Commun. 104, 1470-1476
    • (1982) Biochem. Biophys. Res. Commun. , vol.104 , pp. 1470-1476
    • Rodriguez, L.O.1    Hecht, O.S.2
  • 21
    • 33845587527 scopus 로고    scopus 로고
    • Proton-shuffle mechanism of OO activation for formation of a high-valent oxo-iron species of bleomycin
    • Kumar, D., Hirao, H., Shaik, S., and Kozlowski, P.M. (2006) Proton-shuffle mechanism of O-O activation for formation of a high-valent oxo-iron species of bleomycin. J. Am. Chem. Soc. 128, 16148-16158
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 16148-16158
    • Kumar, D.1    Hirao, H.2    Shaik, S.3    Kozlowski, P.M.4
  • 22
    • 0021929902 scopus 로고
    • Chemical reactivities of bleomycin
    • Padbury, G. and Sligar, S.S. (1985) Chemical reactivities of bleomycin. J. Biol. Chem. 260, 7820-7823
    • (1985) J. Biol. Chem. , vol.260 , pp. 7820-7823
    • Padbury, G.1    Sligar, S.S.2
  • 25
    • 0024430918 scopus 로고
    • The role of iron in oxygen radical mediated lipid peroxidation
    • Minotti, G. and Aust, S.D. (1989) The role of iron in oxygen radical mediated lipid peroxidation. Chem. Biol. Interact. 71, 1-19
    • (1989) Chem. Biol. Interact. , vol.71 , pp. 1-19
    • Minotti, G.1    Aust, S.D.2
  • 26
    • 84878779954 scopus 로고    scopus 로고
    • Redox-derived damage-associated molecular patterns: Ligand function of lipid peroxidation adducts
    • Uchida, K. (2013) Redox-derived damage-associated molecular patterns: ligand function of lipid peroxidation adducts. Redox Biol. 12, 94-96
    • (2013) Redox Biol. , vol.12 , pp. 94-96
    • Uchida, K.1
  • 27
    • 0030796009 scopus 로고    scopus 로고
    • Mechanism of the oxidation of 3,5,30,50-tetramethylbenzidine by myeloperoxidase determined by transient-and steady-state kinetics
    • Marquez, L.A. and Dunford, H.B. (1997) Mechanism of the oxidation of 3,5,30,50-tetramethylbenzidine by myeloperoxidase determined by transient-and steady-state kinetics. Biochemistry 36, 9349-9355
    • (1997) Biochemistry , vol.36 , pp. 9349-9355
    • Marquez, L.A.1    Dunford, H.B.2
  • 28
    • 0020478887 scopus 로고
    • The horseradish peroxidase-catalyzed oxidation of 3,5,30,50-tetramethylbenzidine,free radical and chargetransfer complex intermediates
    • Josephy, P.D., Eling, T., and Mason, R.P. (1982) The horseradish peroxidase-catalyzed oxidation of 3,5,30,50-tetramethylbenzidine. Free radical and chargetransfer complex intermediates. J. Biol. Chem. 257, 3669-3675
    • (1982) J. Biol. Chem. , vol.257 , pp. 3669-3675
    • Josephy, P.D.1    Eling, T.2    Mason, R.P.3
  • 30
    • 0020659381 scopus 로고
    • Effects of iron, copper, cobalt, and their chelators on the cytotoxicity of bleomycin
    • Lin, P.S., Kwock, L., Hefter, K., and Misslbeck, G. (1983) Effects of iron, copper, cobalt, and their chelators on the cytotoxicity of bleomycin. Cancer Res. 43, 1049-1053
    • (1983) Cancer Res. , vol.43 , pp. 1049-1053
    • Lin, P.S.1    Kwock, L.2    Hefter, K.3    Misslbeck, G.4
  • 31
    • 0026545551 scopus 로고
    • On the mechanism of lipoxygenase-like action of bleomycin-iron complexes
    • Kikuchi, H. and Tetsuka, T. (1992) On the mechanism of lipoxygenase-like action of bleomycin-iron complexes. J. Antibiot. (Tokyo) 45, 548-555
    • (1992) J. Antibiot. (Tokyo) , vol.45 , pp. 548-555
    • Kikuchi, H.1    Tetsuka, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.