Measurement of hydroxyl radicals catalyzed in the immediate vicinity of DNAa by metal-bleomycin complexes

Free Radical Biology and Medicine

Volumn 20, Issue 6, 1996, Pages 777-783

  Chakrabarti, Subrata ^a   Makrigiorgos, G Mike ^a,b   O'Brien, Kathryn ^a   Bump, Edward ^a   Kassis, Amin I ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD RADIATION ONCOLOGY PROGRAM   (United States)

Author keywords

Antibiotics; Ascorbate; Bleomycin; Fluorescence; Free radicals; Hydrogen peroxide; Hydroxyl radicals; Iron

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; ASCORBIC ACID; BLEOMYCIN; BLEOMYCIN DERIVATIVE; BLEOMYCIN IRON; BLEOMYCIN SULFATE; CARBOXYLIC ACID DERIVATIVE; COUMARIN DERIVATIVE; FREE RADICAL; HYDROGEN PEROXIDE; HYDROXYL RADICAL; METAL ION; POLYLYSINE; SCAVENGER;

ARTICLE; CARCINOGENICITY; CHROMATIN; DNA DAMAGE; DRUG CONJUGATION; DRUG DNA BINDING; FLUOROMETRY; LUNG TOXICITY; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL;

ANTIBIOTICS, ANTINEOPLASTIC; ASCORBIC ACID; BLEOMYCIN; COUMARINS; DIMETHYL SULFOXIDE; DNA; FERROUS COMPOUNDS; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; POLYLYSINE; SPECTROMETRY, FLUORESCENCE; SUCCINIMIDES;

LETHRINIDAE;

EID: 0029920863     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-5849(95)02160-4     Document Type: Article

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