Putative common origin of two MLH1 mutations in Italian-Quebec hereditary non-polyposis colorectal cancer families

Clinical Genetics

Volumn 66, Issue 2, 2004, Pages 137-143

  Thiffault, I ^a,b   Foulkes, William D ^a,b,c,g   Marcus, V A ^a   Farber, D ^c   Kasprzak, L ^a   MacNamara, E ^c   Wong, N ^c   Hutter, P ^d   Radice, P ^e,f   Bertario, L ^e   Chong, G ^c  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d Institut Central des Hopitaux Valaisans   (Switzerland)

^e NATIONAL CANCER INSTITUTE   (Italy)

^f FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^g MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

Colorectal cancer; Founder mutation; HNPCC; Italian; MLH1; Quebec

Indexed keywords

PROTEIN MLH1;

ADULT; AGED; ARTICLE; CANADA; CANCER INCIDENCE; CHROMOSOME 3; COLORECTAL TUMOR; CONTROLLED STUDY; ETHNOLOGY; FAMILIAL CANCER; FEMALE; GENE IDENTIFICATION; GENE MUTATION; GENE SEGREGATION; HAPLOTYPE; HUMAN; INTERNATIONAL CLASSIFICATION OF DISEASES; ITALY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; CARRIER PROTEINS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; EVOLUTION, MOLECULAR; FOUNDER EFFECT; HAPLOTYPES; HUMANS; IMMUNOHISTOCHEMISTRY; ITALY; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PEDIGREE; QUEBEC; SEQUENCE ANALYSIS, DNA;

STAPHYLOCOCCUS PHAGE 3A;

EID: 4344627626     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2004.00274.x     Document Type: Article

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