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Volumn 12, Issue 2, 2010, Pages 93-104

The cost-effectiveness of genetic testing strategies for Lynch syndrome among newly diagnosed patients with colorectal cancer

Author keywords

Cancer; Cost effectiveness analysis; Economic evaluation; Genetic testing; Genomics; HNPCC; Lynch syndrome

Indexed keywords

ADULT; ARTICLE; COLORECTAL CANCER; COST EFFECTIVENESS ANALYSIS; FAMILIAL CANCER; GENE SEQUENCE; GENETIC ANALYSIS; HEALTH CARE SYSTEM; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; PREVENTIVE HEALTH SERVICE;

EID: 77149122082     PISSN: 10983600     EISSN: None     Source Type: Journal    
DOI: 10.1097/GIM.0b013e3181cd666c     Document Type: Article
Times cited : (254)

References (51)
  • 1
    • 39649088738 scopus 로고    scopus 로고
    • Hereditary nonpolyposis colo-rectal cancer: Diagnostic strategies and their implications
    • Bonis PA, Trikalinos TA, Chung M, et al. Hereditary nonpolyposis colo-rectal cancer: diagnostic strategies and their implications. Evid Rep Technol Assess (Full Rep) 2007;150:1-180.
    • (2007) Evid Rep Technol Assess (Full Rep) , vol.150 , pp. 1-180
    • Bonis, P.A.1    Trikalinos, T.A.2    Chung, M.3
  • 2
    • 59849129653 scopus 로고    scopus 로고
    • EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome
    • Palomaki GE, McClain MR, Melillo S, Hampel HL, Thibodeau SN. EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome. Genet Med 2009;11:1-22.
    • (2009) Genet Med , vol.11 , pp. 1-22
    • Palomaki, G.E.1    McClain, M.R.2    Melillo, S.3    Hampel, H.L.4    Thibodeau, S.N.5
  • 3
    • 59849108362 scopus 로고    scopus 로고
    • Genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives
    • Recommendations from the EGAPP Working Group
    • Recommendations from the EGAPP Working Group. Genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives. Genet Med 2009;11:35-41.
    • (2009) Genet Med , vol.11 , pp. 35-41
  • 4
    • 0032555020 scopus 로고    scopus 로고
    • Incidence of hereditary nonpol-yposis colorectal cancer and the feasibility of molecular screening for the disease
    • Aaltonen LA, Salovaara R, Kristo P, et al. Incidence of hereditary nonpol-yposis colorectal cancer and the feasibility of molecular screening for the disease. N Engl J Med 1998;338:1481-1487.
    • (1998) N Engl J Med , vol.338 , pp. 1481-1487
    • Aaltonen, L.A.1    Salovaara, R.2    Kristo, P.3
  • 5
    • 20244386395 scopus 로고    scopus 로고
    • Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer
    • Pinol V, Castells A, Andreu M, et al. Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer. JAMA 2005;293:1986-1994.
    • (2005) JAMA , vol.293 , pp. 1986-1994
    • Pinol, V.1    Castells, A.2    Andreu, M.3
  • 6
    • 0034799747 scopus 로고    scopus 로고
    • The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer
    • Samowitz WS, Curtin K, Lin HH, et al. The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer. Gastroenterology 2001;121:830-838.
    • (2001) Gastroenterology , vol.121 , pp. 830-838
    • Samowitz, W.S.1    Curtin, K.2    Lin, H.H.3
  • 7
    • 77955053291 scopus 로고    scopus 로고
    • Recommendations to improve identification of hereditary and familial colorectal cancer in Europe
    • [published online ahead of print September 18, 2009] doi:10.1007/s10689- 009-9291-3
    • Vasen HF, Möslein G, Alonso A, et al. Recommendations to improve identification of hereditary and familial colorectal cancer in Europe [published online ahead of print September 18, 2009]. Fam Cancer doi:10.1007/s10689-009- 9291-3.
    • Fam Cancer
    • Vasen, H.F.1    Möslein, G.2    Alonso, A.3
  • 8
    • 45349096041 scopus 로고    scopus 로고
    • Accessed December 31, 2008
    • Cancer Facts and Figures 2008. Available at: http://www.cancer.org/ downloads/STT/2008CAFFfinalsecured.pdf. Accessed December 31, 2008.
    • (2008) Cancer Facts and Figures
  • 9
    • 70349212553 scopus 로고    scopus 로고
    • US Cancer Statistics Working Group Atlanta: US Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute, 2009 Accessed February 19, 2009
    • US Cancer Statistics Working Group. United States cancer statistics: 1999-2005 incidence and mortality web-based report. Atlanta: US Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute, 2009. Available at: www.cdc.gov/uscs. Accessed February 19, 2009.
    • United States Cancer Statistics: 1999-2005 Incidence and Mortality Web-based Report
  • 11
    • 17944362664 scopus 로고    scopus 로고
    • Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer)
    • Hampel H, Frankel WL, Martin E, et al. Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer). N Engl J Med 2005;352:1851-1860.
    • (2005) N Engl J Med , vol.352 , pp. 1851-1860
    • Hampel, H.1    Frankel, W.L.2    Martin, E.3
  • 12
    • 57449097359 scopus 로고    scopus 로고
    • Feasibility of screening for lynch syndrome among patients with colorectal cancer
    • Hampel H, Frankel WL, Martin E, et al. Feasibility of screening for lynch syndrome among patients with colorectal cancer. J Clin Oncol 2008;26: 5783-5788.
    • (2008) J Clin Oncol , vol.26 , pp. 5783-5788
    • Hampel, H.1    Frankel, W.L.2    Martin, E.3
  • 13
    • 65849172834 scopus 로고    scopus 로고
    • A literature review of assumptions on test characteristics and adherence in economic evaluations of colonoscopy and CT-colonography screening
    • van Gils P, van den Berg M, van Kranen H, de Wit AG. A literature review of assumptions on test characteristics and adherence in economic evaluations of colonoscopy and CT-colonography screening. Eur J Cancer 2009;45: 1554-1559.
    • (2009) Eur J Cancer , vol.45 , pp. 1554-1559
    • Van Gils, P.1    Van Den Berg, M.2    Van Kranen, H.3    De Wit, A.G.4
  • 14
    • 0037118705 scopus 로고    scopus 로고
    • Cost-effectiveness analyses of colorectal cancer screening: A systematic review for the U.S. Preventive Services Task Force
    • Pignone M, Saha S, Hoerger T, Mandelblatt J. Cost-effectiveness analyses of colorectal cancer screening: a systematic review for the US Preventive Services Task Force. Ann Intern Med 2002;137:96-104. (Pubitemid 34779153)
    • (2002) Annals of Internal Medicine , vol.137 , Issue.2 , pp. 96-104
    • Pignone, M.1    Saha, S.2    Hoerger, T.3    Mandelblatt, J.4
  • 15
    • 43849100718 scopus 로고    scopus 로고
    • Cost-effectiveness of capsule endos-copy in screening for colorectal cancer
    • Hassan C, Zullo A, Winn S, Morini S. Cost-effectiveness of capsule endos-copy in screening for colorectal cancer. Endoscopy 2008;40:414-421.
    • (2008) Endoscopy , vol.40 , pp. 414-421
    • Hassan, C.1    Zullo, A.2    Winn, S.3    Morini, S.4
  • 16
    • 0033779606 scopus 로고    scopus 로고
    • Cost-effectiveness of colonoscopy in screening for colorectal cancer
    • Sonnenberg A, Delco F, Inadomi JM. Cost-effectiveness of colonoscopy in screening for colorectal cancer. Ann Intern Med 2000;133:573-584. (Pubitemid 30778444)
    • (2000) Annals of Internal Medicine , vol.133 , Issue.8 , pp. 573-584
    • Sonnenberg, A.1    Delco, F.2    Inadomi, J.M.3
  • 17
    • 0035899935 scopus 로고    scopus 로고
    • Cost-effectiveness of microsatellite instability screening as a method for detecting hereditary nonpolyposis colorectal cancer
    • Ramsey SD, Clarke L, Etzioni R, Higashi M, Berry K, Urban N. Cost-effectiveness of microsatellite instability screening as a method for detecting hereditary nonpolyposis colorectal cancer. Ann Intern Med 2001;135:577-588.
    • (2001) Ann Intern Med , vol.135 , pp. 577-588
    • Ramsey, S.D.1    Clarke, L.2    Etzioni, R.3    Higashi, M.4    Berry, K.5    Urban, N.6
  • 18
    • 0142031151 scopus 로고    scopus 로고
    • An economic viewpoint on alternative strategies for identifying persons with hereditary nonpolyposis colorectal cancer
    • Ramsey SD, Burke W, Clarke L. An economic viewpoint on alternative strategies for identifying persons with hereditary nonpolyposis colorectal cancer. Genet Med 2003;5:353-363.
    • (2003) Genet Med , vol.5 , pp. 353-363
    • Ramsey, S.D.1    Burke, W.2    Clarke, L.3
  • 19
    • 34247484551 scopus 로고    scopus 로고
    • Cost-effectiveness of surveillance programs for families at high and moderate risk of hereditary non-polyposis colorectal cancer
    • Olsen KR, Bojesen SE, Gerdes AM, Lindorff-Larsen K, Bernstein IT. Cost-effectiveness of surveillance programs for families at high and moderate risk of hereditary non-polyposis colorectal cancer. Int J Technol Assess Health Care 2007;23:89-95.
    • (2007) Int J Technol Assess Health Care , vol.23 , pp. 89-95
    • Olsen, K.R.1    Bojesen, S.E.2    Gerdes, A.M.3    Lindorff-Larsen, K.4    Bernstein, I.T.5
  • 20
    • 39849083059 scopus 로고    scopus 로고
    • Cost-effectiveness evaluation of predictive molecular diagnostics using the example of hereditary non-polyposis colorectal cancer (HNPCC)
    • Hagen A, Hessabi HK, Gorenoi V, Schonermark MP. [Cost-effectiveness evaluation of predictive molecular diagnostics using the example of hereditary non-polyposis colorectal cancer (HNPCC).] Gesundheitswesen 2008; 70:18-27.
    • (2008) Gesundheitswesen , vol.70 , pp. 18-27
    • Hagen, A.1    Hessabi, H.K.2    Gorenoi, V.3    Schonermark, M.P.4
  • 21
    • 19944397798 scopus 로고    scopus 로고
    • Cost effectiveness of a new strategy to identify HNPCC patients
    • Kievit W, de Bruin JH, Adang EM, et al. Cost effectiveness of a new strategy to identify HNPCC patients. Gut 2005;54:97-102.
    • (2005) Gut , vol.54 , pp. 97-102
    • Kievit, W.1    De Bruin, J.H.2    Adang, E.M.3
  • 22
    • 0003469046 scopus 로고    scopus 로고
    • Gold MR, Siegel JE, Russell LB, Weinstein MC editors New York: Oxford University Press
    • Gold MR, Siegel JE, Russell LB, Weinstein MC, editors. Cost-effectiveness in health and medicine. New York: Oxford University Press, 1996.
    • (1996) Cost-effectiveness in Health and Medicine
  • 24
    • 0442293654 scopus 로고    scopus 로고
    • Cost-effectiveness versus cost-utility analysis of interventions for cancer: Does adjusting for health-related quality of life really matter?
    • Tengs TO. Cost-effectiveness versus cost-utility analysis of interventions for cancer: does adjusting for health-related quality of life really matter? Value Health 2004;7:70-78.
    • (2004) Value Health , vol.7 , pp. 70-78
    • Tengs, T.O.1
  • 25
    • 33745905025 scopus 로고    scopus 로고
    • Preference-based EQ-5D index scores for chronic conditions in the United States
    • Sullivan PW, Ghushchyan V. Preference-based EQ-5D index scores for chronic conditions in the United States. Med Decis Making 2006;26:410-420
    • (2006) Med Decis Making , vol.26 , pp. 410-420
    • Sullivan, P.W.1    Ghushchyan, V.2
  • 26
    • 0034653901 scopus 로고    scopus 로고
    • Quality of life in survivors of colorectal carcinoma
    • Ramsey SD, Andersen MR, Etzioni R, et al. Quality of life in survivors of colorectal carcinoma. Cancer 2000;88:1294-1303.
    • (2000) Cancer , vol.88 , pp. 1294-1303
    • Ramsey, S.D.1    Andersen, M.R.2    Etzioni, R.3
  • 28
    • 77149137122 scopus 로고    scopus 로고
    • Will knowledge of gene-based colorectal cancer disease risk influence quality of life and screening behavior?
    • Ramsey S, Blough D, McDermott C, et al. Will knowledge of gene-based colorectal cancer disease risk influence quality of life and screening behavior? Public Health Genomics 2010;13:1-12.
    • (2010) Public Health Genomics , vol.13 , pp. 1-12
    • Ramsey, S.1    Blough, D.2    McDermott, C.3
  • 29
    • 0037310758 scopus 로고    scopus 로고
    • Colorectal cancer screening and surveillance: Clinical guidelines and rationale-Update based on new evidence
    • Winawer S, Fletcher R, Rex D, et al. Colorectal cancer screening and surveillance: clinical guidelines and rationale-Update based on new evidence. Gastroenterology 2003;124:544-560.
    • (2003) Gastroenterology , vol.124 , pp. 544-560
    • Winawer, S.1    Fletcher, R.2    Rex, D.3
  • 30
    • 22944436125 scopus 로고    scopus 로고
    • Common methodological flaws in economic evaluations
    • Drummond M, Sculpher M. Common methodological flaws in economic evaluations. Med Care 2005;43:5-14.
    • (2005) Med Care , vol.43 , pp. 5-14
    • Drummond, M.1    Sculpher, M.2
  • 31
    • 49249104185 scopus 로고    scopus 로고
    • Interpretation of immu-nohistochemistry for mismatch repair proteins is only reliable in a specialized setting
    • Overbeek LI, Ligtenberg MJ, Willems RW, et al. Interpretation of immu-nohistochemistry for mismatch repair proteins is only reliable in a specialized setting. Am J Surg Pathol 2008;32:1246-1251.
    • (2008) Am J Surg Pathol , vol.32 , pp. 1246-1251
    • Overbeek, L.I.1    Ligtenberg, M.J.2    Willems, R.W.3
  • 32
    • 51549117737 scopus 로고    scopus 로고
    • Bethesda, MD, National Cancer Institute Accessed May 5, 2008
    • Ries L, Melbert D, Krapcho M, et al. SEER Cancer Statistics Review, 1975-2005. Bethesda, MD, National Cancer Institute. Available at: http:// seer.cancer.gov/csr/1975-2005/results-merged/sect-06-colon-rectum.pdf. Accessed May 5, 2008.
    • SEER Cancer Statistics Review 1975-2005
    • Ries, L.1    Melbert, D.2    Krapcho, M.3
  • 33
    • 14544300998 scopus 로고    scopus 로고
    • Systematic review of microsatellite instability and colorectal cancer prognosis
    • Popat S, Hubner R, Houlston RS. Systematic review of microsatellite instability and colorectal cancer prognosis. J Clin Oncol 2005;23:609-618.
    • (2005) J Clin Oncol , vol.23 , pp. 609-618
    • Popat, S.1    Hubner, R.2    Houlston, R.S.3
  • 34
    • 58449114490 scopus 로고    scopus 로고
    • Surveillance colonoscopy improves survival in a cohort of subjects with a single mismatch repair gene mutation
    • Stupart DA, Goldberg PA, Algar U, Ramesar R. Surveillance colonoscopy improves survival in a cohort of subjects with a single mismatch repair gene mutation. Colorectal Dis 2009;11:126-130.
    • (2009) Colorectal Dis , vol.11 , pp. 126-130
    • Stupart, D.A.1    Goldberg, P.A.2    Algar, U.3    Ramesar, R.4
  • 35
    • 28744458014 scopus 로고    scopus 로고
    • Family history assessment to detect increased risk for colorectal cancer: Conceptual considerations and a preliminary economic analysis
    • Ramsey SD, Burke W, Pinsky L, Clarke L, Newcomb P, Khoury MJ. Family history assessment to detect increased risk for colorectal cancer: conceptual considerations and a preliminary economic analysis. Cancer Epidemiol Biomarkers Prev 2005;14:2494-2500.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 2494-2500
    • Ramsey, S.D.1    Burke, W.2    Pinsky, L.3    Clarke, L.4    Newcomb, P.5    Khoury, M.J.6
  • 36
    • 38749113701 scopus 로고    scopus 로고
    • A prospective, multicenter, population-based study of BRAF mutational analysis for Lynch syndrome screening
    • Bessa X, Balleste B, Andreu M, et al. A prospective, multicenter, population-based study of BRAF mutational analysis for Lynch syndrome screening. Clin Gastroenterol Hepatol 2008;6:206-214.
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 206-214
    • Bessa, X.1    Balleste, B.2    Andreu, M.3
  • 37
    • 33745433790 scopus 로고    scopus 로고
    • Priorities among effective clinical preventive services: Methods
    • Maciosek MV, Edwards NM, Coffield AB, et al. Priorities among effective clinical preventive services: methods. Am J Prev Med 2006;31:90-96.
    • (2006) Am J Prev Med , vol.31 , pp. 90-96
    • MacIosek, M.V.1    Edwards, N.M.2    Coffield, A.B.3
  • 38
    • 34249655579 scopus 로고    scopus 로고
    • Lessons from cost-effectiveness research for United States public health policy
    • Grosse SD, Teutsch SM, Haddix AC. Lessons from cost-effectiveness research for United States public health policy. Annu Rev Public Health 2007;28:365-391.
    • (2007) Annu Rev Public Health , vol.28 , pp. 365-391
    • Grosse, S.D.1    Teutsch, S.M.2    Haddix, A.C.3
  • 39
    • 46949100710 scopus 로고    scopus 로고
    • Assessing cost effectiveness in health care: The history of the $50,000 per QALY threshold
    • Grosse SD. Assessing cost effectiveness in health care: the history of the $50,000 per QALY threshold. Exp Rev Pharmacoeconomics Outcome Res 2008;8:165-178.
    • (2008) Exp Rev Pharmacoeconomics Outcome Res , vol.8 , pp. 165-178
    • Grosse, S.D.1
  • 40
    • 41149171625 scopus 로고    scopus 로고
    • What does the value of modern medicine say about the $50, 000 per quality-adjusted life-year decision rule?
    • Braithwaite RS, Meltzer DO, King JT Jr, Leslie D, Roberts MS. What does the value of modern medicine say about the $50,000 per quality-adjusted life-year decision rule? Med Care 2008;46:349-356.
    • (2008) Med Care , vol.46 , pp. 349-356
    • Braithwaite, R.S.1    Meltzer, D.O.2    King Jr., J.T.3    Leslie, D.4    Roberts, M.S.5
  • 41
    • 41149134764 scopus 로고    scopus 로고
    • How much are Americans willing to pay for a quality-adjusted life year?
    • Weinstein MC. How much are Americans willing to pay for a quality-adjusted life year? Med Care 2008;46:343-345.
    • (2008) Med Care , vol.46 , pp. 343-345
    • Weinstein, M.C.1
  • 43
    • 58749101712 scopus 로고    scopus 로고
    • Population-based detection of Lynch syndrome in young colorectal cancer patients using microsatellite instability as the initial test
    • Schofield L, Watson N, Grieu F, et al. Population-based detection of Lynch syndrome in young colorectal cancer patients using microsatellite instability as the initial test. Int J Cancer 2009;124:1097-1102.
    • (2009) Int J Cancer , vol.124 , pp. 1097-1102
    • Schofield, L.1    Watson, N.2    Grieu, F.3
  • 44
    • 29144505362 scopus 로고    scopus 로고
    • Long term follow-up of HNPCC gene mutation carriers: Compliance with screening and satisfaction with counseling and screening procedures
    • Wagner A, van Kessel I, Kriege MG, et al. Long term follow-up of HNPCC gene mutation carriers: compliance with screening and satisfaction with counseling and screening procedures. Fam Cancer 2005;4:295-300.
    • (2005) Fam Cancer , vol.4 , pp. 295-300
    • Wagner, A.1    Van Kessel, I.2    Kriege, M.G.3
  • 45
    • 70350439453 scopus 로고    scopus 로고
    • Ten years after mutation testing for Lynch Syndrome: Cancer incidence and outcome in mutation-positive and mutation-negative family members
    • Järvinen HJ, Renkonen-Sinisalo L, Aktán-Collán K, Peltomäki P, Aaltonen LA, Mecklin JP. Ten years after mutation testing for Lynch Syndrome: cancer incidence and outcome in mutation-positive and mutation-negative family members. J Clin Oncol 2009;27:4793-4797.
    • (2009) J Clin Oncol , vol.27 , pp. 4793-4797
    • Järvinen, H.J.1    Renkonen-Sinisalo, L.2    Aktán-Collán, K.3    Peltomäki, P.4    Aaltonen, L.A.5    Mecklin, J.P.6
  • 46
    • 4644239263 scopus 로고    scopus 로고
    • Colon cancer screening practices following genetic testing for hereditary nonpolyposis colon cancer (HNPCC) mutations
    • Halbert CH, Lynch H, Lynch J, et al. Colon cancer screening practices following genetic testing for hereditary nonpolyposis colon cancer (HNPCC) mutations. Arch Intern Med 2004;164:1881-1887.
    • (2004) Arch Intern Med , vol.164 , pp. 1881-1887
    • Halbert, C.H.1    Lynch, H.2    Lynch, J.3
  • 47
    • 48249113933 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of prevention strategies for gynecologic cancers in Lynch syndrome
    • Kwon JS, Sun CC, Peterson SK, et al. Cost-effectiveness analysis of prevention strategies for gynecologic cancers in Lynch syndrome. Cancer 2008;113:326-335.
    • (2008) Cancer , vol.113 , pp. 326-335
    • Kwon, J.S.1    Sun, C.C.2    Peterson, S.K.3
  • 48
    • 70350090521 scopus 로고    scopus 로고
    • Calculation of risk of colo-rectal and endometrial cancer among patients with Lynch syndrome
    • Stoffel E, Mukherjee B, Raymond VM, et al. Calculation of risk of colo-rectal and endometrial cancer among patients with Lynch syndrome. Gas-troenterology 2009;137:1621-1627.
    • (2009) Gas-troenterology , vol.137 , pp. 1621-1627
    • Stoffel, E.1    Mukherjee, B.2    Raymond, V.M.3
  • 49
    • 20544467125 scopus 로고    scopus 로고
    • Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: Correction for ascertainment
    • Quehenberger F, Vasen HF, van Houwelingen HC. Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainment. J Med Genet 2005;42:491-496.
    • (2005) J Med Genet , vol.42 , pp. 491-496
    • Quehenberger, F.1    Vasen, H.F.2    Van Houwelingen, H.C.3
  • 50
    • 33745658837 scopus 로고    scopus 로고
    • Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer
    • Barnetson RA, Tenesa A, Farrington SM, et al. Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer. N Engl J Med 2006;354:2751-2763.
    • (2006) N Engl J Med , vol.354 , pp. 2751-2763
    • Barnetson, R.A.1    Tenesa, A.2    Farrington, S.M.3


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