Microglial interleukin-1β in the ipsilateral dorsal horn inhibits the development of mirror-image contralateral mechanical allodynia through astrocyte activation in a rat model of inflammatory pain

Pain

Volumn 156, Issue 6, 2015, Pages 1046-1059

  Choi, Hoon Seong ^a   Roh, Dae Hyun ^b   Yoon, Seo Yeon ^a   Moon, Ji Young ^a   Choi, Sheu Ran ^a   Kwon, Soon Gu ^a   Kang, Suk Yun ^c   Han, Ho Jae ^a   Kim, Hyun Woo ^d   Beitz, Alvin J ^e   Oh, Seog Bae ^a   Lee, Jang Hern ^a  

^a Seoul National University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^d Chungnam National University   (South Korea)

^e UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Astrocyte; Interleukin 1 ; Microglia; Mirror image pain

Indexed keywords

CARRAGEENAN; FLUOROCITRIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1BETA; MINOCYCLINE; CITRIC ACID; NERVE PROTEIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CARRAGEENAN-INDUCED INFLAMMATION; CELL ACTIVATION; CONTROLLED STUDY; HIND PAW; INFLAMMATORY PAIN; MALE; MECHANICAL ALLODYNIA; MECHANICAL STIMULATION; MICROGLIA; MIRROR IMAGE PAIN; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPINAL CORD DORSAL HORN; UPREGULATION; ANIMAL; CHEMICALLY INDUCED; COMPLICATION; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; HEMISPHERIC DOMINANCE; HYPERALGESIA; INFLAMMATION; METABOLISM; PAIN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPINAL CORD; SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; CARRAGEENAN; CITRATES; DISEASE MODELS, ANIMAL; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; HYPERALGESIA; INFLAMMATION; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; MALE; MICROGLIA; MINOCYCLINE; NERVE TISSUE PROTEINS; PAIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-1 TYPE I; SPINAL CORD; SPINAL CORD DORSAL HORN;

EID: 84940976909     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1097/j.pain.0000000000000148     Document Type: Article

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