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Volumn 112, Issue 35, 2015, Pages 11001-11006

IRF5 controls both acute and chronic inflammation

Author keywords

Acute inflammation; Arthritis; IRF5; Macrophages; Neutrophils

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CXCL1 CHEMOKINE; CXCL16 CHEMOKINE; CXCL3 CHEMOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON REGULATORY FACTOR 5; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; CHEMOKINE; INTERFERON REGULATORY FACTOR; IRF5 PROTEIN, MOUSE;

EID: 84940975251     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1506254112     Document Type: Article
Times cited : (117)

References (38)
  • 1
    • 38149138096 scopus 로고    scopus 로고
    • Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I
    • Helmick CG, et al.; National Arthritis Data Workgroup (2008) Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I. Arthritis Rheum 58(1):15-25.
    • (2008) Arthritis Rheum , vol.58 , Issue.1 , pp. 15-25
    • Helmick, C.G.1
  • 2
    • 0034545158 scopus 로고    scopus 로고
    • The pathogenesis and prevention of joint damage in rheumatoid arthritis: Advances from synovial biopsy and tissue analysis
    • Tak PP, Bresnihan B (2000) The pathogenesis and prevention of joint damage in rheumatoid arthritis: Advances from synovial biopsy and tissue analysis. Arthritis Rheum 43(12):2619-2633.
    • (2000) Arthritis Rheum , vol.43 , Issue.12 , pp. 2619-2633
    • Tak, P.P.1    Bresnihan, B.2
  • 3
    • 0035002353 scopus 로고    scopus 로고
    • Analysis of the cell infiltrate and expression of matrix metalloproteinases and granzyme B in paired synovial biopsy specimens from the cartilage-pannus junction in patients with RA
    • Smeets TJ, et al. (2001) Analysis of the cell infiltrate and expression of matrix metalloproteinases and granzyme B in paired synovial biopsy specimens from the cartilage-pannus junction in patients with RA. Ann Rheum Dis 60(6):561-565.
    • (2001) Ann Rheum Dis , vol.60 , Issue.6 , pp. 561-565
    • Smeets, T.J.1
  • 4
    • 0030066502 scopus 로고    scopus 로고
    • Synovial tissue macrophage populations and articular damage in rheumatoid arthritis
    • Mulherin D, Fitzgerald O, Bresnihan B (1996) Synovial tissue macrophage populations and articular damage in rheumatoid arthritis. Arthritis Rheum 39(1):115-124.
    • (1996) Arthritis Rheum , vol.39 , Issue.1 , pp. 115-124
    • Mulherin, D.1    Fitzgerald, O.2    Bresnihan, B.3
  • 5
    • 0033711724 scopus 로고    scopus 로고
    • Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis
    • Barrera P, et al. (2000) Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis. Arthritis Rheum 43(9):1951-1959.
    • (2000) Arthritis Rheum , vol.43 , Issue.9 , pp. 1951-1959
    • Barrera, P.1
  • 6
    • 84921813332 scopus 로고    scopus 로고
    • The multifactorial role of neutrophils in rheumatoid arthritis
    • Wright HL, Moots RJ, Edwards SW (2014) The multifactorial role of neutrophils in rheumatoid arthritis. Nat Rev Rheumatol 10(10):593-601.
    • (2014) Nat Rev Rheumatol , vol.10 , Issue.10 , pp. 593-601
    • Wright, H.L.1    Moots, R.J.2    Edwards, S.W.3
  • 7
    • 0019449852 scopus 로고
    • Polymorphonuclear granulocytes in rheumatic tissue destruction. III. An electron microscopic study of PMNs at the pannus-cartilage junction in rheumatoid arthritis
    • Mohr W, Westerhellweg H, Wessinghage D (1981) Polymorphonuclear granulocytes in rheumatic tissue destruction. III. an electron microscopic study of PMNs at the pannus-cartilage junction in rheumatoid arthritis. Ann Rheum Dis 40(4):396-399.
    • (1981) Ann Rheum Dis , vol.40 , Issue.4 , pp. 396-399
    • Mohr, W.1    Westerhellweg, H.2    Wessinghage, D.3
  • 8
    • 34547217463 scopus 로고    scopus 로고
    • Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis
    • Wittkowski H, et al. (2007) Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis. Ann Rheum Dis 66(8): 1020-1025.
    • (2007) Ann Rheum Dis , vol.66 , Issue.8 , pp. 1020-1025
    • Wittkowski, H.1
  • 9
    • 84876104421 scopus 로고    scopus 로고
    • NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis
    • Khandpur R, et al. (2013) NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci Transl Med 5(178):178ra40.
    • (2013) Sci Transl Med , vol.5 , Issue.178
    • Khandpur, R.1
  • 10
    • 84904394690 scopus 로고    scopus 로고
    • Macrophage activation and polarization: Nomenclature and experimental guidelines
    • Murray PJ, et al. (2014) Macrophage activation and polarization: Nomenclature and experimental guidelines. Immunity 41(1):14-20.
    • (2014) Immunity , vol.41 , Issue.1 , pp. 14-20
    • Murray, P.J.1
  • 11
    • 84888063933 scopus 로고    scopus 로고
    • Beyond stem cells: Self-renewal of differentiated macrophages
    • Sieweke MH, Allen JE (2013) Beyond stem cells: Self-renewal of differentiated macrophages. Science 342(6161):1242974.
    • (2013) Science , vol.342 , Issue.6161
    • Sieweke, M.H.1    Allen, J.E.2
  • 12
    • 84911016319 scopus 로고    scopus 로고
    • High-dimensional analysis of the murine myeloid cell system
    • Becher B, et al. (2014) High-dimensional analysis of the murine myeloid cell system. Nat Immunol 15(12):1181-1189.
    • (2014) Nat Immunol , vol.15 , Issue.12 , pp. 1181-1189
    • Becher, B.1
  • 13
    • 84940988389 scopus 로고    scopus 로고
    • Gene expression during the generation and activation of mouse neutrophils: Implication of novel functional and regulatory pathways
    • Ericson JA, et al.; ImmGen Consortium (2014) Gene expression during the generation and activation of mouse neutrophils: Implication of novel functional and regulatory pathways. PLoS One 9(10):e108553.
    • (2014) PLoS One , vol.9 , Issue.10
    • Ericson, J.A.1
  • 14
    • 84919688020 scopus 로고    scopus 로고
    • Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice
    • Misharin AV, et al. (2014) Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice. Cell Reports 9(2):591-604.
    • (2014) Cell Reports , vol.9 , Issue.2 , pp. 591-604
    • Misharin, A.V.1
  • 15
    • 79951671510 scopus 로고    scopus 로고
    • IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
    • Krausgruber T, et al. (2011) IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol 12(3):231-238.
    • (2011) Nat Immunol , vol.12 , Issue.3 , pp. 231-238
    • Krausgruber, T.1
  • 18
    • 57349153093 scopus 로고    scopus 로고
    • Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis
    • Egan PJ, van Nieuwenhuijze A, Campbell IK, Wicks IP (2008) Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis. Arthritis Rheum 58(12):3720-3729.
    • (2008) Arthritis Rheum , vol.58 , Issue.12 , pp. 3720-3729
    • Egan, P.J.1    Van Nieuwenhuijze, A.2    Campbell, I.K.3    Wicks, I.P.4
  • 19
    • 0031975866 scopus 로고    scopus 로고
    • Neutrophils are major contributors to intraparenchymal lung IL-1 beta expression after hemorrhage and endotoxemia
    • Parsey MV, Tuder RM, Abraham E (1998) Neutrophils are major contributors to intraparenchymal lung IL-1 beta expression after hemorrhage and endotoxemia. J Immunol 160(2):1007-1013.
    • (1998) J Immunol , vol.160 , Issue.2 , pp. 1007-1013
    • Parsey, M.V.1    Tuder, R.M.2    Abraham, E.3
  • 20
    • 84894040510 scopus 로고    scopus 로고
    • B cells: Depletion or functional modulation in rheumatic diseases
    • Dorner T, Lipsky PE (2014) B cells: Depletion or functional modulation in rheumatic diseases. Curr Opin Rheumatol 26(2):228-236.
    • (2014) Curr Opin Rheumatol , vol.26 , Issue.2 , pp. 228-236
    • Dorner, T.1    Lipsky, P.E.2
  • 21
    • 77953368347 scopus 로고    scopus 로고
    • Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus
    • Savitsky DA, Yanai H, Tamura T, Taniguchi T, Honda K (2010) Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus. Proc Natl Acad Sci USA 107(22):10154-10159.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.22 , pp. 10154-10159
    • Savitsky, D.A.1    Yanai, H.2    Tamura, T.3    Taniguchi, T.4    Honda, K.5
  • 22
    • 0030809822 scopus 로고    scopus 로고
    • Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice
    • Boring L, et al. (1997) Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. J Clin Invest 100(10): 2552-2561.
    • (1997) J Clin Invest , vol.100 , Issue.10 , pp. 2552-2561
    • Boring, L.1
  • 23
    • 33847340251 scopus 로고    scopus 로고
    • Quantitative analysis of eosinophil chemotaxis tracked using a novel optical device: TAXIScan
    • Nitta N, Tsuchiya T, Yamauchi A, Tamatani T, Kanegasaki S (2007) Quantitative analysis of eosinophil chemotaxis tracked using a novel optical device: TAXIScan. J Immunol Methods 320(1-2):155-163.
    • (2007) J Immunol Methods , vol.320 , Issue.1-2 , pp. 155-163
    • Nitta, N.1    Tsuchiya, T.2    Yamauchi, A.3    Tamatani, T.4    Kanegasaki, S.5
  • 24
    • 0041766160 scopus 로고    scopus 로고
    • Air-pouch models of inflammation and modifications for the study of granuloma-mediated cartilage degradation
    • Colville-Nash P, Lawrence T (2003) Air-pouch models of inflammation and modifications for the study of granuloma-mediated cartilage degradation. Methods Mol Biol 225:181-189.
    • (2003) Methods Mol Biol , vol.225 , pp. 181-189
    • Colville-Nash, P.1    Lawrence, T.2
  • 26
    • 84937542228 scopus 로고    scopus 로고
    • GM-CSF mouse bone marrow cultures comprise a heterogeneous population of CD11c(+)MHCII(+) macrophages and dendritic cells
    • Helft J, et al. (2015) GM-CSF mouse bone marrow cultures comprise a heterogeneous population of CD11c(+)MHCII(+) macrophages and dendritic cells. Immunity 42(6): 1197-1211.
    • (2015) Immunity , vol.42 , Issue.6 , pp. 1197-1211
    • Helft, J.1
  • 27
    • 84922546751 scopus 로고    scopus 로고
    • IRF5:RelA interaction targets inflammatory genes in macrophages
    • Saliba DG, et al. (2014) IRF5:RelA interaction targets inflammatory genes in macrophages. Cell Reports 8(5):1308-1317.
    • (2014) Cell Reports , vol.8 , Issue.5 , pp. 1308-1317
    • Saliba, D.G.1
  • 28
    • 80555133279 scopus 로고    scopus 로고
    • IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation
    • Rider P, et al. (2011) IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation. J Immunol 187(9):4835-4843.
    • (2011) J Immunol , vol.187 , Issue.9 , pp. 4835-4843
    • Rider, P.1
  • 29
    • 84857712400 scopus 로고    scopus 로고
    • The CD14(bright) CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population
    • Rossol M, Kraus S, Pierer M, Baerwald C, Wagner U (2012) The CD14(bright) CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population. Arthritis Rheum 64(3):671-677.
    • (2012) Arthritis Rheum , vol.64 , Issue.3 , pp. 671-677
    • Rossol, M.1    Kraus, S.2    Pierer, M.3    Baerwald, C.4    Wagner, U.5
  • 30
    • 84930571997 scopus 로고    scopus 로고
    • Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity
    • Dalmas E, et al. (2015) Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity. Nat Med 21(6):610-618.
    • (2015) Nat Med , vol.21 , Issue.6 , pp. 610-618
    • Dalmas, E.1
  • 31
    • 84860351105 scopus 로고    scopus 로고
    • Pleiotropic IFN-dependent and -independent effects of IRF5 on the pathogenesis of experimental lupus
    • Xu Y, et al. (2012) Pleiotropic IFN-dependent and -independent effects of IRF5 on the pathogenesis of experimental lupus. J Immunol 188(8):4113-4121.
    • (2012) J Immunol , vol.188 , Issue.8 , pp. 4113-4121
    • Xu, Y.1
  • 32
    • 84866556348 scopus 로고    scopus 로고
    • Monocytes from Irf5-/- mice have an intrinsic defect in their response to pristane-induced lupus
    • Yang L, Feng D, Bi X, Stone RC, Barnes BJ (2012) Monocytes from Irf5-/- mice have an intrinsic defect in their response to pristane-induced lupus. J Immunol 189(7): 3741-3750.
    • (2012) J Immunol , vol.189 , Issue.7 , pp. 3741-3750
    • Yang, L.1    Feng, D.2    Bi, X.3    Stone, R.C.4    Barnes, B.J.5
  • 33
    • 49449103579 scopus 로고    scopus 로고
    • The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature
    • Coelho FM, et al. (2008) The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature. Arthritis Rheum 58(8):2329-2337.
    • (2008) Arthritis Rheum , vol.58 , Issue.8 , pp. 2329-2337
    • Coelho, F.M.1
  • 34
    • 47249141669 scopus 로고    scopus 로고
    • CXCR2-specific chemokines mediate leukotriene B4-dependent recruitment of neutrophils to inflamed joints in mice with antigen-induced arthritis
    • Grespan R, et al. (2008) CXCR2-specific chemokines mediate leukotriene B4-dependent recruitment of neutrophils to inflamed joints in mice with antigen-induced arthritis. Arthritis Rheum 58(7):2030-2040.
    • (2008) Arthritis Rheum , vol.58 , Issue.7 , pp. 2030-2040
    • Grespan, R.1
  • 35
    • 84887557925 scopus 로고    scopus 로고
    • Role of neutrophils in systemic autoimmune diseases
    • Kaplan MJ (2013) Role of neutrophils in systemic autoimmune diseases. Arthritis Res Ther 15(5):219.
    • (2013) Arthritis Res Ther , vol.15 , Issue.5 , pp. 219
    • Kaplan, M.J.1
  • 36
    • 84862132098 scopus 로고    scopus 로고
    • Irf5-deficient mice are protected from pristane-induced lupus via increased Th2 cytokines and altered IgG class switching
    • Feng D, et al. (2012) Irf5-deficient mice are protected from pristane-induced lupus via increased Th2 cytokines and altered IgG class switching. Eur J Immunol 42(6): 1477-1487.
    • (2012) Eur J Immunol , vol.42 , Issue.6 , pp. 1477-1487
    • Feng, D.1
  • 37
    • 15044345461 scopus 로고    scopus 로고
    • Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
    • Takaoka A, et al. (2005) Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 434(7030):243-249.
    • (2005) Nature , vol.434 , Issue.7030 , pp. 243-249
    • Takaoka, A.1


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