Synovial tissue macrophage populations and articular damage in rheumatoid arthritis

Arthritis and Rheumatism

Volumn 39, Issue 1, 1996, Pages 115-124

  Mulherin, Diarmuid ^a   Fitzgerald, Oliver ^a   Bresnihan, Barry ^a  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTHROPATHY; ARTICLE; CELL POPULATION; CLINICAL ARTICLE; DISEASE ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVIUM;

ADULT; AGED; ANTIGENS, CD; ANTIGENS, CD14; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CARTILAGE, ARTICULAR; CELL COUNT; FEMALE; FOLLOW-UP STUDIES; HUMANS; MACROPHAGES; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SYNOVIAL MEMBRANE; TREATMENT OUTCOME;

EID: 0030066502     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780390116     Document Type: Article

References (53)

1. Harris ED: Rheumatoid arthritis: pathophysiology and implications for therapy. N Engl J Med 322:1277-1289, 1990
2. Zvaifler NJ: Etiology and pathogenesis of rheumatoid arthritis. In, Arthritis and Allied Conditions. Twelfth edition. Edited by DJ McCarty, WJ Koopman. Philadelphia, Lea & Febiger, 1993
3. Ishikawa H, Ziff M: Electron microscopic observations of immunoreactive cells in the rheumatoid synovial membrane. Arthritis Rheum 19:1-14, 1976
4. Kobayashi I, Ziff M: Electron microscopic studies of the cartilage-pannus junction in rheumatoid arthritis. Arthritis Rheum 18:475-483, 1975
5. Allard SA, Bayliss MT, Maini RN: The synovium-cartilage junction of the normal human knee: implications for joint destruction and repair. Arthritis Rheum 33:1170-1179, 1990
6. Panayi GS: The immunopathogenesis of rheumatoid arthritis. Br J Rheumatol 32 (Suppl 1):4-14, 1993
7. Firestein GS, Zvaifler NJ: How important are T cells in chronic rheumatoid synovitis? (editorial). Arthritis Rheum 33:768-773, 1990
8. Zvaifler NJ, Firestein GS: Pannus and pannocytes: alternative models of joint destruction in rheumatoid arthritis. Arthritis Rheum 37:783-789, 1994
9. Isaacs JD, Watts RA, Hazleman BL, Hale G, Keogan MT, Cobbold SP, Waldmann H: Humanised monoclonal antibody therapy for rheumatoid arthritis. Lancet 340:748-752, 1992
10. Kirkham BW, Thien F, Pelton BK, Pitzalis C, Amlot P, Denman AM, Panayi GS: Chimeric CD7 monoclonal antibody therapy in rheumatoid arthritis. J Rheumatol 19:1348-1352, 1992
11. Horneff G, Sack U, Kalden JR, Emmrich F, Burmester GR: Reduction of monocyte-macrophage activation markers upon anti-CD4 treatment. Decreased levels of IL-1, IL-6, neopterin and soluble CD14 in patients with rheumatoid artritis. Clin Exp Immunol 91:207-213, 1993
12. Moreland LW, Bucy RP, Tilden A, Pratt PW, LoBuglio AF, Khazaeli M, Everson MP, Daddona P, Ghrayeb J, Kilgarriff C, Sanders ME, Koopman WJ: Use of a chimeric monoclonal anti-CD4 antibody in patients with refractory rheumatoid arthritis. Arthritis Rheum 36:307-318, 1993
13. Van der Lubbe PA, Reiter C, Breedveld FC, Krüger K, Schattenkirchner M, Sanders ME, Riethmùller G: Chimeric CD4 monoclonal antibody cM-T412 as a therapeutic approach to rheumatoid arthritis. Arthritis Rheum 36:1375-1379, 1993
14. Ropes MW, Bennett GA, Cobb S, Jacox R, Jessar RA: 1958 revision of diagnostic criteria for rheumatoid arthritis. Bull Rheum Dis 9:175-176, 1958
15. Rooney M, Whelan A, Feighery C, Bresnihan B: Changes in lymphocyte infiltration of the synovial membrane and the clinical course of rheumatoid arthritis. Arthritis Rheum 32:361-369, 1989
16. Rooney M, Whelan A, Feighery C, Bresnihan B: The immunohistologic features of synovitis, disease activity and in vitro IgM rheumatoid factor synthesis by blood mononuclear cells in rheumatioid arthritis. J Rheumatol 16:459-467, 1989
17. Soden M, Rooney M, Whelan A, Feighery C, Bresnihan B: Immunohistological analysis of the synovial membrane: search for predictors of the clinical course in rheumatoid arthritis. Ann Rheum Dis 50:673-676, 1991
18. Ritchie DM, Boyle JA, McInnes JM, Jasani MK, Dalakos TG, Grieveson P, Buchanan WW: Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis. Q J Med 37:393-406, 1968
19. Mallya RK, Mace BEW: The assessment of disease activity in rheumatoid arthritis using multivariate analysis. Rheumatol Rehabil 20:14-17, 1981
20. Larsen A, Dale K, Eek M: Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films. Acta Radiol Diagn 18:481-491, 1977
21. Dawes PT: Radiological assessment of outcome in rheumatoid arthritis. Br J Rheumatol 27 (Suppl 1):21-36, 1988
22. Poulter LW, Duke O, Hobbs S, Janossy G, Panayi G: Histochemical discrimination of HLA-DR positive cell populations in the normal and arthritic synovial lining. Clin Exp Immunol 48:381-388, 1982
23. Muirden KD, Mills KW: Do lymphocytes protect the rheumatoid joint? Br Med J 4:219-221, 1971
24. Yanni G, Whelan A, Feighery C, Bresnihan B: Synovial tissue macrophages and joint erosion in rheumatoid arthritis. Ann Rheum Dis 53:39-44, 1994
25. Scott DL, Coulton BL, Popert AJ: Long term progression of joint damage in rheumatoid arthritis. Ann Rheum Dis 45:373-378, 1986
26. Scott DL, Grindulis KA, Struthers GR, Coulton BL, Popert AJ, Bacon PA: Progression of radiological changes in rheumatoid arthritis. Ann Rheum Dis 43:8-17, 1984
27. Sany J, Kaliski S, Couret M, Cuchacovich M, Daures J-P: Radiologic progression during intramuscular methotrexate treatment of rheumatoid arthritis. J Rheumatol 17:1636-1641, 1990
28. Weinblatt ME, Kaplan H, Germain BF, Block S, Solomon SD, Merriman RC, Wolfe F, Wall B, Anderson L, Gall E, Torretti D, Weissman B: Methotrexate in rheumatoid arthritis: a five-year prospective multicenter study. Arthritis Rheum 37:1492-1498, 1994
29. Paulus HE, Machleder HI, Levine S, Yu DTY, MacDonald NS: Lymphocyte involvement in rheumatoid arthritis: studies during thoracic duct drainage. Arthritis Rheum 20:1249-1262, 1977
30. Tanay A, Field EH, Hoppe RT, Strober S: Long-term followup of rheumatoid arthritis patients treated with total Lymphoid irradiation. Arthritis Rheum 30:1-10, 1987
31. Soden M, Hassan J, Scott DL, Hanly JG, Moriarty M, Whelan A, Feighery C, Bresnihan B: Lymphoid irradiation in intractable rheumatoid arthritis: long-term followup of patients treated with 750 rads or 2,000 rads. Arthritis Rheum 32:523-530, 1989
32. Walters MT, Smith JL, Moore K, Evans PR, Cawley MID: An investigation of the action of disease modifying antirheumatic drugs on the rheumatoid synovial membrane: reduction in T lymphocyte subpopulations and HLA-DP and DQ antigen expression after gold or penicillamine therapy. Ann Rheum Dis 46:7-16, 1987
33. Yanni G, Nabil M, Farahat MR, Poston RN, Panayi GS: Intramuscular gold decreases cytokine expression and macrophage numbers in the rheumatoid synovial membrane. Ann Rheum Dis 53:315-322, 1994
34. Revell PA: Synovial lining cells. Rheumatol Int 9:49-51, 1989
35. Klareskog L, Forsum U, Malmnäs Tjernlund U, Kabelitz D, Wigren A: Appearance of anti-HLA-DR-reactive cells in normal and rheumatoid synovial tissue. Scand J Immunol 14:183-192, 1981
36. Bröker BM, Edwards JCW, Fanger MW, Lydyard PM: The prevalence and distribution of macrophages bearing Fc γRI, Fc γRII, and Fc γRIII in synovium. Scand J Rheumatol 19:123-135, 1990
37. Burmester GR, Dimitriu-Bona A, Waters SJ, Winchester RJ: Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens and antigens associated with monocytes/macrophages and fibroblasts. Scand J Immunol 17:69-82, 1983
38. Hogg N, Palmer DG, Revell PA: Mononuclear phagocytes of normal and rheumatoid synovial membrane identified by monoclonal antibodies. Immunology 56:673-681, 1985
39. Greywoode GIN, McCarthy SP, McGee JOD: Labelling of cells of the mononuclear phagocyte system in routinely processed archival biopsy specimens with monoclonal antibody EBM/11. J Clin Pathol 43:992-996, 1990
40. Wilkinson LS, Pitsillides AA, Worrall JG, Edwards JCW: Light microscopic characterization of the fibroblast-like synovial intimal cell (synoviocyte). Arthritis Rheum 35:1179-1184, 1992
41. Poulter LW, Campbell DA, Munro C, Janossy G: Discrimination of human macrophages and dendritic cells by means of monoclonal antibodies. Scand J Immunol 24:351-357, 1986
42. Backé E, Schwarting R, Gerdes J, Ernst M, Stein H: Ber-MAC3: new monoclonal antibody that defines a monocyte/ macrophage differentiation antigen. J Clin Pathol 44:936-945, 1991
43. Salisbury AK, Duke O, Poulter LW: Macrophage-like cells of the pannus area in rheumatoid arthritic joints. Scand J Rheumatol 16:263-272, 1987
44. Wilkinson LS, Worrall JG, Sinclair HD, Edwards JCW: Immunohistological reassessment of accessory cell populations in normal and diseased human synovium. Br J Rheumatol 29:259-263, 1990
45. Firestein GS, Zvaifler NJ: Down regulation of human monocyte differentiation antigens by interferon γ. Cell Immunol 104:343-54, 1987
46. McCachren SS, Haynes BF, Niedel JE: Localization of collagenase mRNA in rheumatoid arthritis synovium by in situ hybridization histochemistry. J Clin Immunol 10:19-27, 1990
47. Wood NC, Dickens E, Symons JA, Duff GW: In situ hybridization of interleukin-1 in CD14-positive cells in rheumatoid arthritis. Clin Immunol Immunopathol 62:295-300, 1992
48. MacNaul KL, Hutchinson NI, Parsons JN, Bayne EK, Tocci MJ: Analysis of IL-1 and TNF-α gene expression in human rheumatoid synoviocytes and normal monocytes by in situ hybridization. J Immunol 145:4154-4166, 1990
49. Field M, Chu C, Feldmann M, Maini RN: Interleukin-6 localisation in the synovial membrane in rheumatoid arthritis. Rheumatol Int 11:45-50, 1991
50. Firestein GS, Paine MM: Stromelysin and tissue inhibitor of metalloproteinases gene expression in rheumatoid arthritis synovium. Am J Pathol 140:1309-1314, 1992
51. Chu CQ, Field M, Allard S, Abney E, Feldmann M, Maini RN: Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: implications for the role of cytokines in cartilage destruction and repair. Br J Rheumatol 31:653-661, 1992
52. Firestein GS, Paine MM, Boyle DL: Mechanisms of methotrexate action in rheumatoid arthritis: selective decrease in synovial collagenase gene expression. Arthritis Rheum 37:193-200, 1994
53. Elliot MJ, Maini RN, Feldmann M, Kalden JR, Antoni C, Smolen JS, Leeb B, Breedveld FC, Macfarlane JD, Bijl H, Woody JN: Randomised double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor a (cA2) versus placebo in rheumatoid arthritis. Lancet 344:1105-1110, 1994