eIF4E/Fmr1 double mutant mice display cognitive impairment in addition to ASD-like behaviors

Neurobiology of Disease

Volumn 83, Issue , 2015, Pages 67-74

  Huynh, Thu N ^a   Shah, Manan ^a   Koo, So Yeon ^a   Faraud, Kirsten S ^a   Santini, Emanuela ^a   Klann, Eric ^a  

^a NEW YORK UNIVERSITY   (United States)

Author keywords

Autism spectrum disorders; Cognition; EIF4E; Fragile X syndrome; Genetic models; Protein synthesis; Rodent behavior

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN; INITIATION FACTOR 4E; EIF4E PROTEIN, MOUSE; FMR1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; FRAGILE X SYNDROME; KNOCKOUT MOUSE; LEARNING DISORDER; MALE; MOUSE; MOUSE MODEL; MUTANT MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TRANSGENIC MOUSE; ANIMAL; ANIMAL BEHAVIOR; ANXIETY; C57BL MOUSE; CONDITIONED REFLEX; DISEASE MODEL; FEAR; GENETICS; HIPPOCAMPUS; HUMAN RELATION; MEMORY; METABOLISM; MUTATION; PHYSIOLOGY; PSYCHOLOGY;

ANIMALS; ANXIETY; AUTISM SPECTRUM DISORDER; BEHAVIOR, ANIMAL; COGNITION DISORDERS; CONDITIONING, CLASSICAL; DISEASE MODELS, ANIMAL; EUKARYOTIC INITIATION FACTOR-4E; FEAR; FRAGILE X MENTAL RETARDATION PROTEIN; HIPPOCAMPUS; INTERPERSONAL RELATIONS; MALE; MEMORY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTATION;

EID: 84940944528     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2015.08.016     Document Type: Article

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