Exaggerated translation causes synaptic and behavioural aberrations associated with autism

Nature

Volumn 493, Issue 7432, 2013, Pages 411-415

  Santini, Emanuela ^a   Huynh, Thu N ^a   MacAskill, Andrew F ^a   Carter, Adam G ^a   Pierre, Philippe ^b,c,d   Ruggero, Davide ^e   Kaphzan, Hanoch ^a,f   Klann, Eric ^a  

^a NEW YORK UNIVERSITY   (United States)

^b CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^c INSERM   (France)

^d CNRS   (France)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF HAIFA   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 4E;

BRAIN; GENE EXPRESSION; GENETIC VARIATION; HERITABILITY; INHIBITOR; MENTAL HEALTH; MOLECULAR ANALYSIS; NERVOUS SYSTEM DISORDER; PATHOLOGY; POLYMORPHISM; PROTEIN; RODENT; SYMPTOM;

ANIMAL EXPERIMENT; ARTICLE; AUTISM; BEHAVIOR DISORDER; CONTROLLED STUDY; CORPUS STRIATUM; HIPPOCAMPUS; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; SOCIAL INTERACTION; SYNAPTIC TRANSMISSION; TRANSLATION REGULATION;

ANIMALS; AUTISTIC DISORDER; BEHAVIOR, ANIMAL; DENDRITES; EUKARYOTIC INITIATION FACTOR-4E; EUKARYOTIC INITIATION FACTOR-4G; FEMALE; HIPPOCAMPUS; INFUSIONS, INTRAVENTRICULAR; MALE; MICE; MICE, TRANSGENIC; NEOSTRIATUM; NEURONAL PLASTICITY; NITRO COMPOUNDS; PREFRONTAL CORTEX; PROTEIN BIOSYNTHESIS; RNA CAPS; SYNAPSES; THIAZOLES;

EUKARYOTA; MUS; MUS MUSCULUS;

EID: 84872617263     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11782     Document Type: Article

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