Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails

Cell Research

Volumn 25, Issue 9, 2015, Pages 1013-1024

  Fu, Yanbin ^a   Huang, Chenwen ^a   Xu, Xinxiu ^b   Gu, Haifeng ^b   Ye, Youqiong ^a   Jiang, Cizhong ^a   Qiu, Zilong ^c   Xie, Xin ^a,b  

^a TONGJI UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

cardiac reprogramming; cardiomyocyte; chemical cocktail; fibroblast; small molecule compounds; transdifferentiation

Indexed keywords

4-(2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHALENYL)-1-PROPENYL)BENZOIC ACID; 6 [[2 [[4 (2,4 DICHLOROPHENYL) 5 (4 METHYL 1H IMIDAZOL 2 YL) 2 PYRIMIDINYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; ACTININ; BENZOIC ACID DERIVATIVE; CALCIUM; FORSKOLIN; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; REPSOX; RETINOID; TRANSCRIPTOME; TRANYLCYPROMINE; TROPONIN I; TROPONIN T;

ANIMAL; C57BL MOUSE; CARDIAC MUSCLE CELL; CELL CULTURE; CELL TRANSDIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; ELECTROPHYSIOLOGY; FIBROBLAST; METABOLISM; MOUSE; NUCLEAR REPROGRAMMING; PATCH CLAMP TECHNIQUE;

ACTININ; ANIMALS; BENZOATES; CALCIUM; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; CELLULAR REPROGRAMMING; COLFORSIN; ELECTROPHYSIOLOGICAL PHENOMENA; FIBROBLASTS; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PYRAZOLES; PYRIDINES; PYRIMIDINES; RETINOIDS; TRANSCRIPTOME; TRANYLCYPROMINE; TROPONIN I; TROPONIN T;

EID: 84940892376     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2015.99     Document Type: Article

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