Bacterial adhesion, intracellular survival and cytokine induction upon stimulation of mononuclear cells with planktonic or biofilm phase Staphylococcus epidermidis

FEMS Microbiology Letters

Volumn 330, Issue 1, 2012, Pages 56-65

  Spiliopoulou, Anastasia I ^a,b   Kolonitsiou, Fevronia ^a   Krevvata, Maria I ^a   Leontsinidis, Michalis ^c   Wilkinson, Thomas S ^b   Mack, Dietrich ^b   Anastassiou, Evangelos D ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b SWANSEA UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF PATRAS   (Greece)

Author keywords

Adhesion; Biofilm; Cytokines; Intracellular survival; Mononuclear cells; Planktonic; Staphylococcus epidermidis

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

BACTERIAL CELL; BACTERIAL SURVIVAL; BACTERIUM ADHERENCE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; LETTER; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; QUANTITATIVE ANALYSIS; STAPHYLOCOCCUS EPIDERMIDIS;

BACTERIAL ADHESION; BIOFILMS; CELLS, CULTURED; CYTOKINES; HUMAN EXPERIMENTATION; HUMANS; LEUKOCYTES, MONONUCLEAR; MICROBIAL VIABILITY; STAPHYLOCOCCUS EPIDERMIDIS;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS EPIDERMIDIS;

EID: 84859428367     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2012.02533.x     Document Type: Letter

References (35)

1. Aarag Fredheim EG, Granslo HN, Flægstad T, Figenschau Y, Rohde H, Sadovskaya I, Mollnes TE & Klingenberg C (2011) Staphylococcus epidermidis polysaccharide intercellular adhesin activates complement. FEMS Immunol Med Microbiol 63: 269-280.
2. Arciola CR, Baldassarri L & Montanaro L (2001) Presence of icaA and icaD genes and slime production in a collection of Staphylococcal strains from catheter-associated infections. J Clin Microbiol 39: 2151-2156.
3. Begun J, Gaiani JM, Rohde H, Mack D, Calderwood SB, Ausubel FM & Sifri CD (2007) Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses. PLoS Pathog 3: e57.
4. Cerca N, Martins S, Cerca F, Jefferson KK, Pier GB, Oliveira R & Azeredo J (2005) Comparative assessment of antibiotic susceptibility of coagulase-negative staphylococci in biofilm versus planktonic culture as assessed by bacterial enumeration or rapid XTT colorimetry. J Antimicrob Chemother 56: 331-336.
5. Cerca N, Jefferson KK, Oliveira R, Pier GB & Azeredo J (2006) Comparative antibody-mediated phagocytosis of Staphylocococcus epidermidis cells grown in a biofilm or in the planktonic state. Infect Immun 74: 4849-4855.
6. Christensen GD, Simpson WA, Bisno AL & Beachey EH (1982) Adherence of slime-producing strains of Staphylococcus epidermidis to smooth surfaces. Infect Immun 37: 318-326.
7. Ciornei CD, Novikov A, Beloin C, Fitting C, Caroff M, Ghigo JM, Cavaillon JM & Adib-Conquy M (2010) Biofilm-forming Pseudomonas aeruginosa bacteria undergo lipopolysaccharide structural modifications and induce enhanced inflammatory cytokine response in human monocytes. Innate Immun 16: 288-301.
8. de Silva GDI, Kantzanou M, Justice A, Massey RC, Wilkinson AR, Day NPJ & Peacock SJ (2002) The ica operon and biofilm production in coagulase-negative staphylococci associated with carriage and disease in a neonatal intensive care unit. J Clin Microbiol 40: 382-388.
9. Fallgren C, Andersson A & Ljungh A (2001) The role of glycosaminoglycan binding of Staphylococci in attachment to eukaryotic host cells. Curr Microbiol 43: 57-63.
10. Fey PD (2010) Modality of bacterial growth presents unique targets: how do we treat biofilm-mediated infections? Curr Opin Microbiol 13: 610-615.
11. Foster TJ (2005) Immune evasion by Staphylococci. Nature Rev Microbiol 3: 948-958.
12. Heilmann C, Schweitzer O, Gerke C, Vanittanakom N, Mack D & Götz F (1996) Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis. Mol Microbiol 20: 1083-1091.
13. Heinzelmann M, Herzig D, Swain B, Mercer-Jones M, Bergamini T & Polk H (1997) Phagocytosis and oxidative-burst response of planktonic Staphylococcus epidermidis RP62A and its non-slime-producing variant in human neutrophils. Clin Diagn Lab Immunol 4: 705-710.
14. Hogan D & Kolter R (2002) Why are bacteria refractory to antimicrobials? Curr Opin Microbiol 5: 472-477.
15. Koskela A, Nilsdotter-Augustinson A, Persson L & Soderquist B (2009) Prevalence of the ica operon and insertion sequence IS256 among Staphylococcus epidermidis prosthetic joint infection isolates. Eur J Clin Microbiol Infect Dis 28: 655-660.
16. Kristian SA, Birkenstock TA, Sauder U, Mack D, Götz F & Landmann R (2008) Biofilm formation induces C3a release and protects Staphylococcus epidermidis from IgG and complement deposition and from neutrophil-dependent killing. J Infect Dis 197: 1028-1035.
17. Mack D, Siemssen N & Laufs R (1992) Parallel induction of glucose of adherence and a polysaccharide antigen specific for plastic-adherent Staphylococcus epidermidis: evidence for functional relation to intercellular adhesion. Infect Immun 60: 2048-2057.
18. Mack D, Fischer W, Krokotsch A, Leopold K, Hartmann R, Egge H & Laufs R (1996) The intercellular adhesin involved in biofilm accumulation of Staphylococcus epidermidis is a linear β-1, 6-linked glucosaminoglycan: purification and structural analysis. J Bacteriol 178: 175-183.
19. Mack D, Bartscht K, Fischer C, Rohde H, De Grahl C, Dobinsky S, Horstkotte MA, Kiel K & Knobloch JK-M (2001) Genetic and biochemical analysis of Staphylococcus epidermidis biofilm accumulation in biofilms of Staphylococci. Methods in Enzymology Vol. 336 (R.J. Doyle, ed), pp. 215-239. Academic Press, San Diego, CA, 92101, USA.
20. Mack D, Davies A, Harris L, Rohde H, Horstkotte M & Knobloch J (2007) Microbial interactions in Staphylococcus epidermidis biofilms. Anal Bioanal Chem 387: 399-408.
21. Meja KK, Seldon PM, Nasuhara Y, Ito K, Barnes PJ, Lindsay MA & Giembycz MA (2000) p38 MAP kinase and MKK-1 co-operate in the generation of GM-CSF from LPS-stimulated human monocytes by an NF-kappa B-independent mechanism. Br J Pharmacol 131: 1143-1153.
22. Meluleni GJ, Grout M, Evans DJ & Pier GB (1995) Mucoid Pseudomonas aeruginosa growing in a biofilm in vitro are killed by opsonic antibodies to the mucoid exopolysaccharide capsule but not by antibodies produced during chronic lung infection in cystic fibrosis patients. J Immunol 155: 2029-2038.
23. Resch A, Rosenstein R, Nerz C & Götz F (2005) Differential gene expression profiling of Staphylococcus aureus cultivated under biofilm and planktonic conditions. Appl Environ Microbiol 71: 2663-2676.
24. Resch A, Leicht S, Saric M, Pásztor L, Jakob A, Götz F & Nordheim A (2006) Comparative proteome analysis of Staphylococcus aureus biofilm and planktonic cells and correlation with transcriptome profiling. Proteomics 6: 1867-1877.
25. Schommer NN, Christner M, Hentschke M, Ruckdeschel K, Aepfelbacher M & Rohde H (2011) Staphylococcus epidermidis uses distinct mechanisms of biofilm formation to interfere with phagocytosis and activation of mouse macrophage-like cells 774A.1. Infect Immun 79: 2267-2276.
26. Secor PR, James GA, Fleckman P, Olerud JE, McInnerney K & Stewart PS (2011) Staphylococcus aureus Biofilm and Planktonic cultures differentially impact gene expression, mapk phosphorylation, and cytokine production in human keratinocytes. BMC Microbiol 11: 143.
27. Shi Y, Liu CH, Roberts AI et al. (2006) Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know. Cell Res 16: 126-133.
28. Shiau AL & Wu CL (1998) The inhibitory effect of Staphylococcus epidermidis slime on the phagocytosis of murine peritoneal macrophages is interferon-independent. Microbiol Immunol 42: 33-40.
29. Singh R, Ray P, Das A & Sharma M (2010) Penetration of antibiotics through Staphylococcus aureus and Staphylococcus epidermidis biofilms. J Antimicrob Chemother 65: 1955-1958.
30. Stevens NT, Sadovskaya I, Jabbouri S, Sattar T, O'Gara JP, Humphreys H & Greene CM (2009) Staphylococcus epidermidis polysaccharide intercellular adhesin induces IL-8 expression in human astrocytes via a mechanism involving TLR2. Cell Microbiol 11: 421-432.
31. von Eiff C, Peters G & Heilmann C (2002) Pathogenesis of infections due to coagulase-negative staphylococci. Lancet Infect Dis 2: 677-685.
32. Vuong C & Otto M (2002) Staphylococcus epidermidis infections. Microbes Infect 4: 481-489.
33. Vuong C, Voyich JM, Fischer ER, Braughton KR, Whitney AR, Deleo FR & Otto M (2004) Polysaccharide intercellular adhesion (PIA) protects Staphylococcus epidermidis against major components of the human immune system. Cell Microbiol 6: 269-275.
34. Watnick P & Kolter R (2000) Biofilm, city of microbes. J Bacteriol 182: 2675-2679.
35. Ziebuhr W, Krimmer V, Rachid S, Lobner I, Gotz F & Hacker J (1999) A novel mechanism of phase variation of virulence in Staphylococcus epidermidis: evidence for control of the polysaccharide intercellular adhesin synthesis by alternating insertion and excision of the insertion sequence element IS256. Mol Microbiol 32: 345-350.