(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation

EMBO Reports

Volumn 16, Issue 9, 2015, Pages 1114-1130

  Fiesel, Fabienne C ^a   Ando, Maya ^a   Hudec, Roman ^a   Hill, Anneliese R ^a   Castanedes Casey, Monica ^a   Caulfield, Thomas R ^a   Moussaud Lamodière, Elisabeth L ^a   Stankowski, Jeannette N ^a   Bauer, Peter O ^a   Lorenzo Betancor, Oswaldo ^a   Ferrer, Isidre ^b,c   Arbelo, José M ^d   Siuda, Joanna ^e   Chen, Li ^f   Dawson, Valina L ^f,g,h   Dawson, Ted M ^f,g,h   Wszolek, Zbigniew K ⁱ   Ross, Owen A ^a   Dickson, Dennis W ^a   Springer, Wolfdieter ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^d HOSPITAL UNIVERSITARIO INSULAR DE GRAN CANARIA   (Spain)

^e MEDICAL UNIVERSITY OF SILESIA   (Poland)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g ADRIENNE HELIS MALVIN MEDICAL RESEARCH FOUNDATION   (United States)

^h Diana Helis Henry Medical Research Foundation   (United States)

ⁱ MAYO CLINIC   (United States)

Author keywords

early onset Parkinson's disease; mitophagy; Parkin; phosphorylated ubiquitin; PINK1

Indexed keywords

PARKIN; PHOSPHOSPECIFIC ANTIBODY; PHOSPHOTRANSFERASE; PINK1 KINASE; UBIQUITIN; UNCLASSIFIED DRUG; ANTIBODY; BIOLOGICAL MARKER; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ARTICLE; BRAIN CELL CULTURE; CATALYSIS; CELL FRACTIONATION; CELL GRANULE; CONTROLLED STUDY; CROSS REACTION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; ENZYME ACTIVITY; FIBROBLAST; GENE MUTATION; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR WEIGHT; MOUSE; NERVE CELL; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; ANIMAL; BRAIN; CYTOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; MITOCHONDRION; MITOPHAGY; MUTATION; PARKINSON DISEASE; PHOSPHORYLATION; PHYSIOLOGY; UBIQUITINATION; ULTRASTRUCTURE;

ANIMALS; ANTIBODIES; BIOMARKERS; BRAIN; FIBROBLASTS; HELA CELLS; HUMANS; MICE; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MUTATION; NEURONS; PARKINSON DISEASE; PHOSPHORYLATION; PROTEIN KINASES; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84940776745     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201540514     Document Type: Article

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