AuNP flares-capped mesoporous silica nanoplatform for MTH1 detection and inhibition

Biomaterials

Volumn 69, Issue , 2015, Pages 212-221

  Gao, Wen ^a,b   Cao, Wenhua ^a,b   Sun, Yuhui ^a,b   Wei, Xueping ^a,b   Xu, Kehua ^a,b   Zhang, Huaibin ^a,b   Tang, Bo ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG NORMAL UNIVERSITY   (China)

Author keywords

AuNP flares; Cancer theranostic; Detection; Inhibition; Mesoporous silica nanoparticle; MTH1

Indexed keywords

DISEASES; ENZYME INHIBITION; ERROR DETECTION; GOLD NANOPARTICLES; MESOPOROUS MATERIALS; NANOPARTICLES; SILICA; THERANOSTICS;

ANTI-CANCER THERAPIES; AUNP FLARES; CANCER THERANOSTIC; CAPPED MESOPOROUS SILICA; MESOPOROUS SILICA NANOPARTICLES; MTH1; RECOGNITION SEQUENCE; VULNERABILITY FACTORS;

SILICA NANOPARTICLES;

ANTINEOPLASTIC AGENT; CRIZOTINIB; CYANINE DYE; ENZYME; GOLD NANOPARTICLE; GOLD NANOPARTICLE CAPPED MESOPOROUS SILICA NANOPARTICLE; MESOPOROUS SILICA NANOPARTICLE; MESSENGER RNA; MUTT HOMOLOGUE 1; UNCLASSIFIED DRUG; 8-OXODGTPASE; DNA LIGASE; ENZYME INHIBITOR; GOLD; NANOPARTICLE; PHOSPHATASE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; SILICON DIOXIDE; SINGLE STRANDED DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER DIAGNOSIS; CANCER THERAPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG FORMULATION; DRUG PROTEIN BINDING; DRUG RELEASE; DRUG RESPONSE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; FLUORESCENCE; HELA CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HYBRIDIZATION; MALE; MOUSE; NONHUMAN; POROSITY; PRIORITY JOURNAL; RED LIGHT; RNA BINDING; TUMOR XENOGRAFT; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; GENETICS; NEOPLASMS; NUCLEOTIDE SEQUENCE; NUDE MOUSE; TUMOR CELL LINE;

ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; DNA REPAIR ENZYMES; DNA, SINGLE-STRANDED; ENZYME INHIBITORS; GOLD; HUMANS; MALE; MICE; MICE, NUDE; NANOPARTICLES; NEOPLASMS; PHOSPHORIC MONOESTER HYDROLASES; PYRAZOLES; PYRIDINES; RNA, MESSENGER; SILICON DIOXIDE;

EID: 84940772995     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.08.021     Document Type: Article

References (30)

1. Dawane J.S., Pandit V.A. Understanding redox homeostasis and its role in cancer. J. Clin. Diagn. Res. 2012, 6:1796-1802.
2. Oka S., Ohno M., Tsuchimoto D., Sakumi K., Furuichi M., Nakabeppu Y. Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs. EMBO J. 2008, 27:421-432.
3. Jorgenson T.C., Zhong W., Oberley T.D. Redox imbalance and biochemical changes in cancer. Cancer Res. 2013, 73:6118-6123.
4. Gad H., Koolmeister T., Jemth A.S., Eshtad S., Jacques S.A., Ström C.E., et al. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature 2014, 508:215-221.
5. Huber K.V.M., Salah E., Radic B., Gridling M., Elkins J.M., Stukalov A., et al. Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. Nature 2014, 508:222-227.
6. Oda H., Nakabeppu Y., Furuichi M., Sekiguchi M. Regulation of expression of the human MTH1 gene encoding 8-oxo-dGTPase. Alternative splicing of transcription products. J. Biol. Chem. 1997, 272:17843-17850.
7. Yoshimura D., Sakumi K., Ohno M., Sakai Y., Furuichi M., Iwai S., et al. An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress. J. Biol. Chem. 2003, 278:37965-37973.
8. Schmidt M.C., Mccartney R.R., Zhang X., Tillman T.S., Solimeo H., Lfl S.W., et al. Std1 and Mth1 proteins interact with the glucose sensors to control glucose-regulated gene expression in saccharomyces cerevisiae. Mol. Cell Biol. 1999, 19:4561-4571.
9. 3 nanoparticles for induction of cancer cell-specific apoptosis and real-time imaging. Biomaterials 2012, 33:3710-3718.
10. Lu H.-Y., Chang Y.-J., Fan N.-C., Wang L.-S., Lai N.-C., Yang C.-M., et al. Synergism through combination of chemotherapy and oxidative stress-induced autophagy in A549 lung cancer cells using redox-responsive nanohybrids: a new strategy for cancer therapy. Biomaterials 2015, 42:30-41.
11. Seferos D.S., Giljohann D.A., Hill H.D., Prigodich A.E., Mirkin C.A. Nano-flares: probes for transfection and mRNA detection in living cells. J. Am. Chem. Soc. 2007, 129:15477-15479.
12. Li N., Chang C., Pan W., Tang B. A multicolor nanoprobe for detection and imaging of tumor-related mRNAs in living cells. Angew. Chem. Int. Ed. 2012, 51:7426-7430.
13. Meng H., Mai W.X., Zhang H., Xue M., Xia T., Lin S., et al. Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo. ACS Nano 2013, 7:994-1005.
14. Climent E., Martínez-Máñez R., Sancenón F., Marcos M.D., Soto J., Maquieira A., et al. Controlled delivery using oligonucleotide-capped mesoporous silica nanoparticles. Angew. Chem. Int. Ed. 2010, 49:7281-7283.
15. Calvo A., Yameen B., Williams F.J., Soler-Illia G.J.A.A., Azzaroni O. Mesoporous films and polymer brushes helping each other to modulate ionic transport in nanoconfined environments. An interesting example of synergism in functional hybrid assemblies. J. Am. Chem. Soc. 2009, 131:10866-10868.
16. Mal N.K., Fujiwara M., Tanaka Y. Photocontrolled reversible release of guest molecules from coumarin-modified mesoporous silica. Nature 2003, 421:350-353.
17. Casasús R., Climent E., Marcos M.D., Martínez-Máñez R., Sancenón F., Soto J., et al. Dual aperture control on pH- and anion-driven supramolecular nanoscopic hybrid gate-like ensembles. J. Am. Chem. Soc. 2008, 130:1903-1907.
18. Saha S., Leung K.C.F., Nguyen T.D., Stoddart J.F., Zink J.I. Nanovalves. Adv. Funct. Mater. 2007, 17:685-693.
19. 2+-T base pairs mediated duplex DNA. J. Mater Chem. B 2013, 1:1552-1560.
20. Li N., Yu Z., Pan W., Han Y., Zhang T., Tang B. A near-infrared light-triggered nanocarrier with reversible DNA valves for intracellular controlled release. Adv. Funct. Mater. 2013, 23:2255-2262.
21. Ma M., Chen H., Chen Y., Wang X., Chen F., Cui X., et al. Au capped magnetic core/mesoporous silica shell nanoparticles for combined photothermo-/chemo-therapy and multimodal imaging. Biomaterials 2012, 33:989-998.
22. Muhammad F., Guo M., Qi W., Sun F., Wang A., Guo Y., et al. pH-triggered controlled drug release from mesoporous silica nanoparticles via intracelluar dissolution of ZnO nanolids. J. Am. Chem. Soc. 2011, 133:8778-8781.
23. Aznar E., Marcos M.D., Martínez-Máñez R., Sancenón F., Soto J., Amorós P., et al. pH- and photo-switched release of guest molecules from mesoporous silica supports. J. Am. Chem. Soc. 2009, 131:6833-6843.
24. Liu R., Zhang Y., Zhao X., Agarwal A., Mueller L.J., Feng P. pH-responsive nanogated ensemble based on gold-capped mesoporous silica through an acid-labile acetal linker. J. Am. Chem. Soc. 2010, 132:1500-1501.
25. Vivero-Escoto J.L., Slowing I.I., Wu C.W., Lin V.S. Photoinduced intracellular controlled release drug delivery in human cells by gold-capped mesoporous silica nanosphere. J. Am. Chem. Soc. 2009, 131:3462-3463.
26. Zikich D., Borovok N., Molotsky T., Kotlyar A. Synthesis and AFM characterization of poly(dG)-poly(dC)-gold nanoparticle conjugates. Bioconjugate Chem. 2010, 21:544-547.
27. Demers L.M., Mirkin C.A., Mucic R.C., Reynolds R.A., Letsinger R.L., Elghanian R., et al. A fluorescence-based method for determining the surface coverage and hybridization efficiency of thiol-capped oligonucleotides bound to gold thin films and nanoparticles. Anal. Chem. 2000, 72:5535-5541.
28. Kim J., Kim H.S., Lee N., Kim T., Kim H., Yu T., et al. Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery. Angew. Chem. Int. Ed. 2008, 47:8438-8441.
29. Fan C., Wang S., Hong J.W., Bazan G.C., Plaxco K.W., Heeger A.J. Beyond superquenching: hyper-efficient energy transfer from conjugated polymers to gold nanoparticles. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:6297-6310.
30. Seferos D.S., Prigodich A.E., Giljohann D.A., Patel P.C., Mirkin C.A. Polyvalent DNA nanoparticle conjugates stabilize nucleic acids. Nano Lett. 2009, 9:308-311.