Autocrine type I interferon amplifies dendritic cell responses to lipopolysaccharide via the nuclear factor-κB/p38 pathways

Scandinavian Journal of Immunology

Volumn 63, Issue 3, 2006, Pages 151-154

  Pollara, G ^a   Handley, M E ^a   Kwan, A ^a   Chain, B M ^a   Katz, D R ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD86 ANTIGEN; CYTOKINE; HLA DR ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

AUTOCRINE EFFECT; CELL ACTIVATION; CELL FUNCTION; CELL MATURATION; CELL STIMULATION; CELLULAR IMMUNITY; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME ACTIVATION; HUMAN; IMMUNE RESPONSE; INFECTION; MICROENVIRONMENT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; UPREGULATION;

ANTIGENS, CD86; CELL DIFFERENTIATION; DENDRITIC CELLS; HUMANS; INTERFERON TYPE I; LIPOPOLYSACCHARIDES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33644821748     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2006.01727.x     Document Type: Review

References (18)

1. Pollara G Kwan A Newton PJ Handley ME Chain BM Katz DR Dendritic cells in viral pathogenesis: protective or defective? Int J Exp Pathol 2005 86 187 204
2. Sporri R Reis e Sousa C Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function Nat Immunol 2005 6 163 70
3. Pollara G Jones M Handley ME et al. Herpes simplex virus type-1-induced activation of myeloid dendritic cells: the roles of virus cell interaction and paracrine type I IFN secretion J Immunol 2004 173 4108 19
4. Asselin-Paturel C Brizard G Chemin K et al. Type I interferon dependence of plasmacytoid dendritic cell activation and migration J Exp Med 2005 201 1157 67
5. Gautier G Humbert M Deauvieau F et al. A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells J Exp Med 2005 201 1435 46
6. Handley ME Thakker M Pollara G Chain BM Katz DR JNK activation limits dendritic cell maturation in response to reactive oxygen species by the induction of apoptosis Free Radic Biol Med 2005 38 1637 52
7. Gauzzi MC Canini I Eid P Belardelli F Gessani S Loss of type I IFN receptors and impaired IFN responsiveness during terminal maturation of monocyte-derived human dendritic cells J Immunol 2002 169 3038 45
8. Honda K Sakaguchi S Nakajima C et al. Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection Proc Natl Acad Sci USA 2003 100 10872 7
9. Yoshimura S Bondeson J Foxwell BM Brennan FM Feldmann M Effective antigen presentation by dendritic cells is NF-kappaB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines Int Immunol 2001 13 675 83
10. Ardeshna KM Pizzey AR Devereux S Khwaja A The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells Blood 2000 96 1039 46
11. Murphy TL Cleveland MG Kulesza P Magram J Murphy KM Regulation of interleukin 12 p40 expression through an NF-kappa B half-site Mol Cell Biol 1995 15 5258 67
12. Grumont R Hochrein H O'Keeffe M et al. c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription J Exp Med 2001 194 1021 32
13. Wang SW Pawlowski J Wathen ST Kinney SD Lichenstein HS Manthey CL Cytokine mRNA decay is accelerated by an inhibitor of p38-mitogen-activated protein kinase Inflamm Res 1999 48 533 8
14. Saccani S Pantano S Natoli G p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment Nat Immunol 2002 3 69 75
15. Liu J Cao S Herman LM Ma X Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-{gamma}-primed IL-12 production by IFN regulatory factor 1 J Exp Med 2003 198 1265 76
16. Blanco P Palucka AK Gill M Pascual V Banchereau J Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus Science 2001 294 1540 3
17. Luft T Luetjens P Hochrein H et al. IFN-{alpha} enhances CD40 ligand-mediated activation of immature monocyte-derived dendritic cells Int Immunol 2002 14 367 80
18. Kamath AT Sheasby CE Tough DF Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-{alpha}{beta} and IFN-{gamma} J Immunol 2005 174 767 76