Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma

Oncotarget

Volumn 6, Issue 25, 2015, Pages 21718-21729

  Faria, Claudia C ^a,b,c   Agnihotri, Sameer ^a   Mack, Stephen C ^a   Golbourn, Brian J ^a   Diaz, Roberto J ^a   Olsen, Samantha ^a   Bryant, Melissa ^a   Bebenek, Matthew ^a   Wang, Xin ^a   Bertrand, Kelsey C ^a   Kushida, Michelle ^a   Head, Renee ^a   Clark, Ian ^a   Dirks, Peter ^a   Smith, Christian A ^a   Taylor, Michael D ^a   Rutka, James T ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b HOSPITAL DE SANTA MARIA   (Portugal)

^c INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

Author keywords

Alsterpaullone; Connectivity map; Group 3 medulloblastoma; Piperlongumine

Indexed keywords

ALSTERPAULLONE; FLUNARIZINE; PIPERLONGUMINE; PLANT MEDICINAL PRODUCT; ROTTLERIN; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; ACETOPHENONE DERIVATIVE; ANTINEOPLASTIC AGENT; BENZAZEPINE DERIVATIVE; BENZOPYRAN DERIVATIVE; CYCLIN DEPENDENT KINASE; INDOLE DERIVATIVE; MYC PROTEIN; MYC PROTEIN, HUMAN; PIPERLONGUMININE; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; COMPUTER MODEL; CONTROLLED STUDY; DOWN REGULATION; DRUG IDENTIFICATION; DRUG SCREENING; DRUG TARGETING; GENE EXPRESSION; GROUP 3 MEDULLOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; MEDULLOBLASTOMA; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; ONCOGENE MYC; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN NEOPLASMS; CANCER TRANSPLANTATION; CELL LINE; CHEMISTRY; GENE EXPRESSION PROFILING; GENOMICS; METABOLISM; METASTASIS; PROGNOSIS;

ACETOPHENONES; ANIMALS; ANTINEOPLASTIC AGENTS; BENZAZEPINES; BENZOPYRANS; BRAIN NEOPLASMS; CELL LINE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASES; DIOXOLANES; DRUG SCREENING ASSAYS, ANTITUMOR; FLUNARIZINE; GENE EXPRESSION PROFILING; GENOMICS; HUMANS; INDOLES; MEDULLOBLASTOMA; MICE; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-MYC; RNA;

EID: 84940758213     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4304     Document Type: Article

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