Ca2+ influx-mediated dilation of the endoplasmic reticulum and c-FLIPL downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells

Oncotarget

Volumn 6, Issue 25, 2015, Pages 21173-21192

  Jeong, Soo Ah ^a   Kim, In Young ^a   Lee, A Reum ^a   Yoon, Mi Jin ^a   Cho, Hyeseong ^a   Lee, Jong Soo ^b   Choi, Kyeong Sook ^a  

^a Ajou University School of Medicine   (South Korea)

^b Ajou University   (South Korea)

Author keywords

Apoptosis; C FLIPL; Ca2+; CDDO Me; Endoplasmic reticulum

Indexed keywords

2 CYANO 3, 12 DIOXOOLEANA 1, 9(11) DIEN C28 METHYL ESTER; ANTINEOPLASTIC AGENT; CALCIUM ION; CASPASE; FLICE INHIBITORY PROTEIN; REACTIVE OXYGEN METABOLITE; TRITERPENOID; UNCLASSIFIED DRUG; CALCIUM; CFLAR PROTEIN, HUMAN; METHYL 2-CYANO-3,12-DIOXOOLEAN-1,9-DIEN-28-OATE; OLEANOLIC ACID; SUPEROXIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CANCER CELL; CELL DAMAGE; CELL VACUOLE; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM DILATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; ANALOGS AND DERIVATIVES; BREAST NEOPLASMS; CELL SURVIVAL; CHEMISTRY; CYTOSOL; FEMALE; GENE EXPRESSION REGULATION; METABOLISM; MITOCHONDRION; PATHOLOGY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CALCIUM; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL LINE, TUMOR; CELL SURVIVAL; CYTOSOL; DOWN-REGULATION; ENDOPLASMIC RETICULUM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; OLEANOLIC ACID; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 84940746877     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4065     Document Type: Article

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