Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation

Biochemical and Biophysical Research Communications

Volumn 465, Issue 3, 2015, Pages 542-547

  Park, Jeong Su ^a   Kang, Dong Hoon ^b   Lee, Da Hyun ^a   Bae, Soo Han ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Ewha Womans University   (South Korea)

Author keywords

Autophagy; Fenofibrate; Keap1; Nrf2; p62; PPAR

Indexed keywords

FENOFIBRATE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN P62; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; ANTILIPEMIC AGENT; CYTOSKELETON PROTEIN; HEAT SHOCK PROTEIN; KEAP1 PROTEIN, MOUSE; NFE2L2 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL VIABILITY; DOWN REGULATION; EMBRYO; FATTY ACID OXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; ANIMAL; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; FIBROBLAST; METABOLISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FENOFIBRATE; FIBROBLASTS; HEAT-SHOCK PROTEINS; HYPOLIPIDEMIC AGENTS; MICE; NF-E2-RELATED FACTOR 2; REACTIVE OXYGEN SPECIES;

EID: 84940706308     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.08.056     Document Type: Article

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